Occupancy of dipeptidyl peptidase IV activates an associated tyrosine kinase and triggers an apoptotic signal in human hepatocarcinoma cells

Hepatology

Volumn 27, Issue 4, 1998, Pages 934-942

  Gaetaniello, Lucia ^a   Fiore, Michele ^a   De Filippo, Sergio ^a   Pozzi, Nicola ^a   Tamasi, Sonia ^a   Pignata, Claudio ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CD45 ANTIGEN; DIPEPTIDYL PEPTIDASE IV; ORTHOVANADIC ACID; PHOSPHATASE; PROTEIN TYROSINE KINASE;

ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HEP 2 CELL; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; LIVER CELL CARCINOMA; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

ANTIGENS, CD26; ANTIGENS, CD45; APOPTOSIS; CARCINOMA, HEPATOCELLULAR; HUMANS; LIVER NEOPLASMS; PHOSPHOLIPASE C; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; TUMOR CELLS, CULTURED; TYROSINE;

EID: 0031925072     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.510270407     Document Type: Article

References (3)

1. Heike M, Mobius U, Knuth A, Meuer S, Meyer Zum Buschenfelde KH. Tissue distribution of the T cell activation antigen Tal. Serological, immunohistochemical and biochemical investigations. Clin Exp Immunol 1988;74:431-434.
2. Torimoto Y, Dang NH, Tanaka T, Prado C, Schlossman SF, Morimoto C. Biochemical characterization of CD26 (dipeptidyl peptidase IV): functional comparison of distinct epitopes recognised by various anti-CD26 monoclonal antibodies. Mol Immunol 1992;29:183-192.
3. Morimoto C, Torimoto Y, Levinson G, Rudd CE, Schrieber M, Dang NH, Letvin NL. 1F7, a novel surface molecule, involved in helper function of CD4 cells. J Immunol 1989;143:3430-3439.