Polymorphism of motilin gene in patients with Crohn's disease

Digestive Diseases and Sciences

Volumn 43, Issue 4, 1998, Pages 715-719

  Annese, Vito ^a   Piepoli, Ada ^a   Andriulli, Angelo ^a   Napolitano, Grazia ^a   Bisceglia, Luigi ^a   Zelante, Leopoldo ^a   Gasparini, Paolo ^a  

^a CASA SOLLIEVO DELLA SOFFERENZA HOSPITAL   (Italy)

Author keywords

Crohn's disease; Inflammatory bowel disease; Motilin; Ulcerative colitis

Indexed keywords

MOTILIN; NEUTROPHIL CYTOPLASMIC ANTIBODY;

ADULT; AMINO ACID SUBSTITUTION; ANTIBODY DETECTION; ARTICLE; CROHN DISEASE; DNA DETERMINATION; DNA POLYMORPHISM; FEMALE; GENE FREQUENCY; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN VARIANT; ULCERATIVE COLITIS;

ADULT; ALLELES; ANTIBODIES, ANTINEUTROPHIL CYTOPLASMIC; CASE-CONTROL STUDIES; COLITIS, ULCERATIVE; CROHN DISEASE; FEMALE; HUMANS; MALE; MOTILIN; POLYMORPHISM, GENETIC; VARIATION (GENETICS);

EID: 0031924901     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1018897510504     Document Type: Article

References (29)

1. Yang H, Rotter JI: Genetics of inflammatory bowel disease. In. Inflammatory Bowel Disease. From the Bench to the Bedside. SR Targan, F Shanahan (eds). Baltimore, Williams & Wilkins, 1994, pp 32-64
2. Sugimura K, Asakura H, Mizuki N, Inoue M, Hibi T, Yagita A, Tsuji K: Analysis of genes within the HLA region affecting susceptibility to ulcerative colitis. Hum Immunol 36:112-118, 1993
3. Toyoda H, Wang SJ, Yang HY, Redford A, Magalong D, Tyan D, McElree CK, Pressman SR, Shanahan F, Targan SR: Distinct association of HLA class II genes with inflammatory bowel diseases. Gastroenterology 104:741-748, 1993
4. Gardener KR, Crockard AD, Halliday MI, Rowlands BJ: Class II major histocompatibility complex antigen expression on peripheral blood monocytes in patients with inflammatory bowel disease. Gut 35:511-516, 1994
5. Nakajima A, Matsuhashi N, Kodama T, Yazaki Y, Takazoe M, Kimura A: HLA-linked susceptibility and resistance genes in Crohn's disease. Gastroenterology 109:1462-1467, 1995
6. Reishagen M, Loeliger C, Kuehnl P, Weiss U, Manfras BJ, Adler G, Boehm BO: HLA class II gene frequencies in Crohn's disease: A population based analysis in Germany. Gut 38:538-542, 1996
7. Danzè PM, Colombel JF, Jacquot S, Loste MN, Heresbach D, Ategbo S, Khamassi S, Pèrichon B, Semana G, Charron D, Cèzard JP: Association of HLA class II genes with susceptibility to Crohn's disease. Gut 39:69-72, 1996
8. Duerr RH, Neigut DA: Molecular defined HLA-DR2 alleles in ulcerative colitis and an antincutrophil cytoplasmic antibody-positive subgroup. Gastroenterology 108:423-427, 1995
9. Yang H, Rotter JI, Toyoda H, Landers C, Tyran D, McElree CK, Targan SR: Ulcerative colitis: A genetically heterogeneous disorder defined by genetic (HLA class II) and subclinical (antineutrophil cytoplasmatic antibodies markers). J Clin Invest 92:1080-1084, 1993
10. Yang H, Targan SR, Toyoda H, Tyan D, Landers C, McElree CK, Rotter JI: Exploring the mode of inheritance of ANCA + and ANCA-ulcerative colitis in the HLA locus. Gastroenterology 104:A804, 1993
11. Annese V, Piepoli A, Napolitano G, Perri F, Caruso N, Ciavarella G, Andriulli A: Are HLA and pANCA markers of genetic heterogeneity in ulcerative colitis? Gastroenterology 108:A771, 1995
12. Masuda H, Nakamura Y, Tanaka T, Hayakawa S: Distinct relationship between HLA-DR genes and intractability of ulcerative colitis. Am J Gastroenterol 89:1957-1962, 1994
13. Sandborn WJ, Landers CJ, Tremaine WJ, Targan SR: The presence of antineutrophil cytoplasmatic antibodies correlates with pouchitis after ileal pouch-anal anastomosis for ulcerative colitis. Gastroenterology 104:A774, 1993
14. Cohen Tervaert JW, Kallenberg GGM: Anti-neutrophil cytoplasmatic antibodies (ANCA) in sera from patients with inflammatory bowel disease. Relation to disease pattern and disease activity. Dig Dis Sci 39:545-549, 1994
15. Gasparini P, Grifa A, Savasta S, Merlo I, Bisceglia L, Totaro A, Zelante L: The motilin gene: Subregional localisation, tissue expression, DNA poly-morphisms and exclusion as a candidate gene for the HLA-associated immotile cylia syndrome. Hum Genet 94:671-674, 1994
16. Vantrappen G, Janssens J, Peeters TL, Bloom SR, Christofides MC, Hellemans J: Motilin and the interdigestive migrating motor complex in man. Dig Dis Sci 24:437-500, 1979
17. Peeters TL, Vantrappen G, Janssens J: Fasting plasma motilin levels are related to the interdigestive motility complex. Gastroenterology 79:716-719, 1980
18. Annese V, Bassotti G, Napolitano G, Usai P, Andriulli A, Vantrappen G: Gastrointestinal motility disorders in patients with inactive Crohn's disease. Scand J Gastroenterol 1997 32:1107-1117, 1997
19. Boyum A: Separation of leucocytes from blood and bone marrow. Scand J Clin Invest 21:31-50, 1988
20. Wiik A: Delineation of a standard procedure for indirect immuno-fluorescence detection of ANCA. APMIS 97(suppl 6):12-13, 1988
21. Sambrook J, Fritsch EF, Maniatis F: Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, New York, Cold Spring Harbor Laboratory Press, 1989
22. Annese V, Lombardi G, Piepoli A, Perri F, Caruso N, Napolitano G, Arfili L, Andriulli A: Clinical heterogeneity of inflammatory bowel disease (IBD) in relation to the presence of antineutrophil cytoplasmatic antibodies. Gastroenterology 110:A854, 1996
23. Patel RT, Stokes R, Birch C, Ibbotson J, Keighley MRB: Influence of total colectomy on serum antineutrophil cytoplasmatic antibodies in inflammatory bowel disease. Br J Surg 81:724-726, 1994
24. Vasiliauskas EA, Plevy SE, Landers CJ, Binder SW, Ferguson DM, Yang H, Rotter JI, Vidrich A, Targan SR: Perinuclear antineutrophil cytoplasmatic antibodies in patients with Crohn's disease define a clinical subgroup. Gastroenterology 110:1810-1819, 1996
25. Plevy SE, Targan SR, Yang H, Fernandez D, Rotter JI, Toyoda H: Tumor necrosis factor microsatellites define a Crohn's disease-associated haplotype on chromosome 6. Gastroenterology 110:1053-1060, 1996
26. Vlasuk GP, Inouye S, Ito H, Itakura K, Inouye M: Effects of the complete removal of basic amino acid residues from the signal peptide on secretion of lipoprotein in Escherichia coli. J Biol Chem 258:7141-7148, 1983
27. Hortin G, Boime I: Inhibition of preprotein processing in ascites tumor lysates by incorporation of a leucine analog. Proc Natl Acad Sci USA 77:1356-1360, 1980
28. Poitras P: Motilin. In: Dockray GJ, Walsh JH (eds). Gut Peptides: Biochemistry and Physiology. New York, Raven Press, 1993, pp 261-303
29. Annese V, Vantrappen G: Gall stones in Crohn's disease: Another hypothesis. Gut 35:1676, 1994 (letter)