Arginine, fish oil, and donor-specific transfusions independently improve cardiac allograft survival in rats given subtherapeutic doses of cyclosporin

Journal of Parenteral and Enteral Nutrition

Volumn 22, Issue 3, 1998, Pages 152-155

  Alexander, J Wesley ^a   Levy, Adam ^b   Custer, David ^a   Valente, John F ^a   Babcock, George ^a   Ogle, Cora K ^a   Schroeder, Timothy J ^a  

^a UNIVERSITY OF CINCINNATI MEDICAL CENTER   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; CYCLOSPORIN A; FISH OIL; IMMUNOSUPPRESSIVE AGENT;

ALLOGRAFT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIET SUPPLEMENTATION; DIET THERAPY; GRAFT REJECTION; GRAFT SURVIVAL; HEART TRANSPLANTATION; IMMUNOSUPPRESSIVE TREATMENT; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; ORGAN TRANSPLANTATION; PRIORITY JOURNAL; RAT; SUBCUTANEOUS DRUG ADMINISTRATION; TREATMENT OUTCOME;

EID: 0031924822     PISSN: 01486071     EISSN: None     Source Type: Journal    
DOI: 10.1177/0148607198022003152     Document Type: Article

References (27)

1. Levy AE, Alexander JW: Nutritional immunomodulation enhances cardiac allograft survival in rats treated with donor specific transfusion and CsA. Transplantation 60:812-815, 1995
2. Ono K, Lindsey ES: Improved technique of heart transplantation in rats. J Thorac Cardiovasc Surg 57:225-229, 1969
3. Alexander JW, MacMillan BG, Stinnett JD, et al: Beneficial effects of aggressive protein feeding in severely burned children. Ann Surg 192:505-517, 1980
4. Gianotti L, Alexander JW, Pyles T, et al: Arginine-supplemented diets improve survival in gut-derived sepsis and peritonitis by modulating bacterial clearance: The role of nitric oxide. Ann Surg 217:644-654, 1993
5. Ogle CK, Ogle JD, Mao J-X, et al: Effect of glutamine on phagocytosis and bacterial killing by normal and patient neutrophils. JPEN 18:128-133, 1994
6. Gianotti L, Alexander JW, Gennari R, et al: Oral glutamine decreases bacterial translocation and improves survival in experimental gut-origin sepsis. JPEN 14:69-74, 1995
7. Gianotti L, Alexander JW, Pyles T, et al: Dietary fatty acids modulate host bactericidal response, microbial translocation and survival following blood transfusion and thermal injury. Clin Nutr 15:291-296, 1996
8. Gottschlich MM, Jenkins M, Warden GD, et al: Differential effects of three enteral dietary regimens on selected outcome variables in burn patients. JPEN 14:225-236, 1990
9. Daly JM, Weintraub FN, Shou J, et al: Enterai nutrition during multimodality therapy in upper gastrointestinal cancer patients. Ann Surg 221:327-38, 1995
10. Moore FA, Moore EE, Kudsk KA, et al: Clinical benefits of an immune-enhancing diet for early postinjury enteral feeding. J Trauma 37:607-615, 1994
11. Bower RH, Cerra FB, Bershadsky B, et al: Early enteral administration of a formula (Impact) supplemented with arginine, nucleotides, and fish oil in intensive care patients: Results of a multicenter, prospective, randomized, clinical trial. Crit Care Med 23:436-449, 1995
12. Keinen M: European multicenter study in postoperative cancer patients. J Crit Care Nutr 3:22-23, 1995
13. Daly JM, Lieberman MD, Goldfine J, et al: Enterai nutrition with supplemental arginine, RNA, and omega-3 fatty acids in patients after operation: Immunologic, metabolic, and clinical outcome. Surgery 112:56-67, 1992
14. Kudsk, KA, Minard G, Croce MA, et al: A randomized trial of isonitrogenous enteral diets following severe trauma: An immune-enhancing diet (IED) reduces septic complications. Ann Surg 224:531-543, 1996
15. Mossman TR, Coffman RL: Th1 and Th2 cells: Different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol 7:145-173, 1989
16. Lowry RP, Takeuchi T: The Th-1, Th-2 paradigm of transplantation tolerance: Cellular and molecular mechanisms. IN Transplantation Tolerance Induction, Alexander JW, Good RA (eds). RA Landes Co, Springer, New York, 1966, pp 91-111, 1966
17. Levy A, Alexander JW: Administration of intragraft IL-4 prolongs cardiac allograft survival in rats treated with DST/CsA. Transplantation 60:405-406, 1995
18. Frede SE, Valente J, Alexander JW, et al: The relationship of blood transfusion and immunosuppression with the Th1/Th2 paradigm. Transplant Proc 29:1153-1154, 1997
19. Babcock GF, Alexander JW: The effects of blood transfusions on the cytokine production of Th1 and Th2 lymphocytes in the mouse. Transplantation 61:465-468, 1996
20. Reynolds JV, Daly JM, Zhang S, et al: Immunomodulatory mechanisms of arginine. Surgery 104:142-151, 1988
21. Madden HP, Breslin RJ, Wasserkrug HL, et al: Stimulation of T-cell immunity by arginine enhances survival in peritonitis. J Surg Res 44:658-663, 1988
22. Gianotti L, Alexander JW, Pyles T, et al: Arginine-supplemented diets improve survival in gut-derived sepsis and peritonitis by modulating bacterial clearance: The role of nitric oxide. Ann Surg 217:644-654, 1993
23. Saito H, Trocki O, Wang SL, et al: Metabolic and immune effects of dietary arginine supplementation after burn. Arch Surg 122:784-789, 1987
24. Taylor-Robinson AW, Liew FY, Severn A, et al: Regulation of the immune response by nitric oxide differentially produced by T helper type 1 and T helper type 2 cells. Eur J Immunol 24:980-984, 1994
25. van der Heide JJ, Bilo HJ, Donker JM, et al: Effect of dietary fish oil on renal function and rejection in Cyclosporirie-treated recipients of renal transplants. N Engl J Med 329:769-773, 1993
26. Shapiro AC, Wu D, Meydari SN: Eicosanoids derived from arachidonic and eicosapentaenoic acids inhibit T cell proliferative response. Prostaglandins 45:222-240, 1993
27. Hummel DS: Dietary lipids and immune function. Prog Food Nutr Sci 17:287-329, 1993