IL-4- and IL-5-positive T lymphocytes, eosinophils, and mast cells in allergen-induced late-phase cutaneous reactions in atopic subjects

Journal of Allergy and Clinical Immunology

Volumn 101, Issue 2 I, 1998, Pages 222-230

  Barata, Luis T ^a   Ying, Sun ^a   Meng, Qiu ^a   Barkans, Julia ^a   Rajakulasingam, Karalasingam ^a   Durham, Stephen R ^a   Kay, A Barry ^a  

^a IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

Author keywords

Allergic inflammation; Interleukin; mRNA; Protein; Skin

Indexed keywords

ALLERGEN; CD3 ANTIGEN; INTERLEUKIN 4; INTERLEUKIN 5;

ADULT; ALLERGIC REACTION; ARTICLE; ATOPY; CLINICAL ARTICLE; EOSINOPHIL; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INFLAMMATORY CELL; MACROPHAGE ACTIVATION; MALE; MAST CELL; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSITIZATION; SKIN MANIFESTATION; T LYMPHOCYTE ACTIVATION;

EID: 0031924658     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-6749(98)70387-2     Document Type: Article

References (33)

1. + lymphocytes, activated eosinophils and the magnitude of the allergen-induced late phase skin reaction in man. J Immunol 1988;141:4158-64.
2. Gaga M, Frew AJ, Varney V, Kay AB. Eosinophil activation and T lymphocyte infiltration in allergen-induced late phase reaction and classical delayed-type hypersensitivity. J Immunol 1991;147:816-22.
3. Dolovich J, Hargreave FE, Chalmers R, Shier KJ, Gauldie J, Bienenstock J. Late cutaneous allergic responses in isolated IgE-dependent reaction. J Allergy Clin Immunol 1973;52:38-46.
4. Solley GO, Gleich GJ, Jordan RE, Schroeter AL. The late phase of the immediate wheal and flare skin reaction: its dependence upon IgE antibodies. J Clin Invest 1976;58:408-20.
5. Kay AB, Ying S, Varney V, Durham SR, Moqbel R, Wardlaw AJ, et al. Messenger RNA expression of the cytokine gene cluster, IL-3, IL-4, IL-5, and GM-CSF, in allergen-induced late-phase reactions in atopic subjects. J Exp Med 1991;173:775-8.
6. Tsicopoulos A, Hamid Q, Haczku A, Jacobson MR, Durham SR, North J, et al. Kinetics of cells infiltration and cytokine messenger RNA expression after intradermal challenge with allergen and tuberculin in the same atopic individuals. J Allergy Clin Immunol 1994;94:764-72.
7. Ying S, Durham SR, Jacobson MR, Rak S, Masuyama K, Lowhagen O, et al. T lymphocytes and mast cells express messenger RNA for interleukin-4 in the nasal mucosa in allergen-induced rhinitis. Immunology 1994;82:200-6.
8. Ying S, Durham SR, Barkans J, Masuyama K, Jacobson MR, Rak S, et al. T cells are the principal source of interleukin-5 mRNA in allergen-induced rhinitis. Am J Respir Cell Mol Biol 1993;9:356-60.
9. Ying S, Durham SR, Corrigan CJ, Hamid Q, Kay AB. Phenotype of cells expressing mRNA for TH2-type (interleukin 4 and interleukin 5) and TH1-type (interleukin 2 and Interferon γ) cytokines in bronchoalveolar lavage and bronchial biopsies from atopic asthmatics and normal control subjects. Am J Respir Cell Mol Biol 1995;12:477-87.
10. Bradding P, Roberts JA, Britten KM, Montefort S, Djukanovic R, Mueller R, et al. Interleukin-4, -5 and -6 and tumor necrosis factor-a in normal and asthmatic airways: evidence for the human mast cell as a source of these cytokines. Am J Respir Cell Mol Biol 1994;10: 471-80.
11. Bradding P, Feather IH, Wilson S, Barding PG, Heusser CH, Holgate ST, et al. Immunolocalization of cytokines in the nasal mucosa of normal and perennial rhinitis subjects. J Immunol 1993; 151:3853-65.
12. Kita H, Weiler DA, Abu-Ghazaleh R, Sanderson CJ, Gleich GJ. Release of granule proteins from eosinophils cultured with IL-5. J Immunol 1992;149:629-35.
13. Moqbel R, Ying S, Barkans J, Newman TM, Kimmitt P, Wakelin M, et al. Identification of messenger RNA for IL-4 in human eosinophils with granule localization and release of the translated product. J Immunol 1995;155:4939-47.
14. Ying S, Meng Q, Barata TL, Corrigan CJ, Barkans J, Assoufi B, et al. Human eosinophils express messenger RNA encoding RANTES and store and release biologically active RANTES protein. Eur J Immunol 1996;26:70-6.
15. Humbert M, Durham SR, Ying S, Kimmitt P, Bakans J, Assoufi B, et al. IL-4 and IL-5 mRNA and protein in bronchial biopsies from patients with atopic and nonatopic asthma: evidence against 'intrinsic' asthma being a distinct immunopathologic entity. Am J Respir Crit Care Med 1996;154:1497-1504.
16. Hansel TT, de Vries UM, Iff MT, Rihs S, Wandzilak M, Betz S, et al. An improved immunomagnetic procedure for the isolation of high purified human blood eosinophils. J Immunol Method 1991; 145:105-12.
17. Winqvist I, Olofsson T, Olsson I. Mechanisms for eosinophil degranulation: release of the eosinophil cationic protein. Immunol 1984; 51:1-8.
18. Abu-Ghazaleh RI, Fujisawa T, Mestecky J, Kyle RA, Gleich GJ. IgA-induced eosinophil degranulation. J Immunol 1989;142:2393-400.
19. Chomocyzynski P, Sacchi N. Single step method of RNA isolation by acid guanidium thiocyanate phenol-chloroform extraction. Annu Biochem 1987;162:156-9.
20. Doi S, Gemou-Engesaeth V, Kay AB, Corrigan CJ. Polymerase chain reaction quantification of cytokine messenger RNA expression in peripheral blood mononuclear cells of patients with severe asthma: effect of glucocorticoid therapy. Clin Exp Allergy 1994;24: 854-67.
21. Bradding P, Okayama Y, Howarth PH, Church MK, Holgate ST. Heterogeneity of human mast cells based on cytokine content. J Immunol 1995;155:297-307.
22. Bos JD, Hagenaars C, Das PK, Krieg SR, Voorn WJ, Kapsenberg ML. Predominance of 'memory' T cells (CD4 +, Cdw29 +) over 'naive' T cells (CD4+, CD45R+) in both normal and diseased human skin. Arch Dermatol Res 1989;281:24-30.
23. Bos JD, Kapsenberg ML. The skin immune system: progress in cutaneous biology. Immunol Today 1993;14:75-8.
24. Craig SS, Schecher NM, Schwartz LB. Ultrastructural analysis of maturing human T and TC mast cells in situ. Lab Invest 1989;60: 147-57.
25. Irani AM, Craig SS, DeBlois G, Elson CO, Schechter NM, Schwartz LB. Deficiency of the tryptase-positive, chymase-negative mast cell type in gastrointestinal mucosa of patients with defective T lymphocyte function. J Immunol 1987;138:4381-6.
26. Nonaka M, Nonaka R, Woolley K, Adelroth E, Miura K, Okhawara Y, et al. Distinct immunohistochemical localization of IL-4 in human inflamed airway tissue: IL-4 is localized to eosinophils in vivo and is released by peripheral blood eosinophils. J Immunol 1995;155:3234-44.
27. Dubucquoi S, Desreumaux P, Janin A, Klein O, Goldman M, Tavernier J, et al. Interleukin 5 synthesis by eosinophils: association with granules and immunoglobulin-dependent secretion. J Exp Med 1994;179:703-8.
28. Soussi Gounni A, Lamkhioued B, Ochiai K, Tanaka Y, Delaporate E, Capron A, et al. High-affinity IgE receptor on eosinophils is involved in defense against parasites. Nature 1994;367:183-6.
29. + eosinophils in human atopic skin. Eur J Immunol 1997;27:1236-41.
30. + cells. Adv Immunol 1993;53:1-29.
31. van Reijsen FC, Bruijnzeel-Koomen CAFM, Kalthoff FS, Maggi E, Romagnani S, Westland JKT, et al. Skin-derived aeroallergen-specific T-cell clones of Th2 phenotype in patients with atopic dermatitis. J Allergy Clin Immunol 1992;90:182-92.
32. + T cell lines in atopic asthmatics, and atopic and non-atopic controls. Eur J Immunol 1995;25:2727-31.
33. + T cells, eosinophils and mast cells in bronchial biopsies obtained from atopic and non-atopic (intrinsic) asthmatics. J Immunol 1997;158:3539-44.