Positive and negative regulation of Easter, a member of the serine protease family that controls dorsal-ventral patterning in the Drosophila embryo

Development

Volumn 125, Issue 7, 1998, Pages 1261-1267

  Misra, Sima ^a   Hecht, Peter ^a,c   Maeda, Robert ^a   Anderson, Kathryn V ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Weill Cornell Graduate School of Biomedical Sciences   (United States)

^c WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

Dorsal ventral patterning; Easter; Serine protease; Serpin; Zymogen

Indexed keywords

ENZYME PRECURSOR; LIGAND; SERINE PROTEINASE; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOCHEMISTRY; DEVELOPMENTAL GENETICS; DROSOPHILA; EMBRYO; EMBRYO PATTERN FORMATION; GENETIC ORGANIZATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ANIMALIA; ARACHNIDA; HEXAPODA;

EID: 0031924060     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Anderson, K. V., Jürgens, G. and Nüsslein-Volhard, C. (1985). Establishment of dorsal-ventral polarity in the Drosophila embryo: genetic studies on the role of the Toll gene product. Cell 42, 779-789.
2. Anderson, K. V. and Nüsslein-Volhard, C. (1984). Information for the dorsal-ventral pattern of the Drosophila embryo is stored as maternal mRNA. Nature 311, 223-227.
3. Anderson, K. V. and Nüsslein-Volhard, C. (1986). Dorsal-group genes of Drosophila. In Gametogenesis and the Early Embryo (ed. J. Gall), pp. 177-194. New York: Alan Liss.
4. Chasan, R. and Anderson, K. V. (1989). The role of easter, an apparent serine protease, in organising the dorsal-ventral pattern of the Drosophila embryo. Cell 56, 391-400.
5. Chasan, R., Jin, Y. and Anderson, K. V. (1992). Activation of the easter zymogen is regulated by rive other genes to define dorsal-ventral polarity in the Drosophila embryo. Development 115, 607-616.
6. Coleman, S., Drahn, B., Petersen, G., Stolorov, J. and Kraus, K. (1995). A Drosophila male accessory gland protein that is a member of the serpin superfamily of proteinase inhibitors is transferred to females during mating. Insect Biochem. Mol. Biol. 25, 203-207.
7. DeLotto, R. and Spierer, P. (1986). A gene required for the specification of dorsal-ventral pattern in Drosophila appears to encode a serine protease. Nature 323, 688-692.
8. Golembo, M., Schweitze, R. R., Freeman, M. and Shilo, B. Z. (1996). Argos transcription is induced by the Drosophila EGF receptor pathway to form an inhibitory feedback loop. Development 122, 223-230.
9. Hashimoto, C., Gerttula, S. and Anderson, K.V. (1991). Plasma membrane localization of the Toll protein in the syncytial Drosophila embryo: importance of transmembrane signaling for dorsal-ventral pattern formation. Development 111, 1021-1028.
10. Hecht, P. (1993). Ph.D. thesis. University of California, Berkeley.
11. Hecht, P. M. and Anderson, K. V. (1992). Extracellular proteases and embryonic pattern formation. Trends in Cell Biology 2, 197-202.
12. Hecht, P. M. and Anderson, K. V. (1993). Genetic characterization of tube and pelle, genes required for signaling between Toll and dorsal in the specification of the dorsal-ventral pattern of the Drosophila embryo. Genetics 135, 405-417.
13. Hong, C. C. and Hashimoto, C. (1995). An unusual mosaic protein with a protease domain, encoded by the nudel gene, is involved in defining embryonic dorsoventral polarity in Drosophila. Cell 82, 785-794.
14. Jiang, H., Wang, Y. and Kanost, M. R. (1994). Mutually exclusive exon use and reactive center diversity in insect serpins. J. Biol. Chem. 269, 55-58.
15. Jin, Y. (1991). Ph.D. thesis. University of California, Berkeley.
16. Jin, Y. and Anderson, K.V. (1990). Dominant and recessive alleles of the Drosophila easter gene are point mutations at conserved sites in the serine protease domain. Cell 60, 873-881.
17. Konrad, K. and Marsh, J. L. (1990). The gastrulation defective (gd) gene displays homology to serine proteases. A. Conf. Dros. Res. 31, 43-44.
18. Laskowski, M. and Kato, I. (1980). Protein inhibitors of proteinases. Ann. Rev. Biochem. 49, 593-626.
19. Morisato, D. and Anderson, K. V. (1994). The spätzle gene encodes a component of the extracellular signaling pathway establishing the dorsal-ventral pattern of the Drosophila embryo. Cell 76, 677-688.
20. Morisato, D. and Anderson, K. V. (1995). Signaling pathways that establish the dorsal-ventral pattern of the Drosophila embryo. Ann. Rev. Genetics 29, 371-399.
21. Nüsslein-Volhard, C. (1979). Materal effect mutations that alter the spatial coordinates of the embryo of Drosophila melanogaster. Symp. Soc. Dev. Biol. 37, 185-211.
22. Potempa, J., Korzus, E. and Travis, J. (1994). The serpin superfamily of proteinase inhibitors: structure, function and regulation. J. Biol Chem. 269, 15957-15960.
23. Roth, S., Stein, D. and Nüsslein-Volhard, C. (1989). A gradient of nuclear localization of the dorsal protein determines dorsoventral pattern in the Drosophila embryo. Cell 59, 1189-1202.
24. Roth, S., Hiromi, Y., Godt, D. and Nüsslein-Volhard, C. (1991) cactus, a maternal gene required for proper formation of the dorsoventral morphogen gradient in Drosophila embryos. Development 112, 371-388.
25. Rushlow, C. A., Han, K., Manley, J. L. and Levine, M. (1989). The graded distribution of the dorsal morphogen is initiated by selective nuclear transport in Drosophila. Cell 59, 1165-1177.
26. Schneider, D. S., Jin, Y., Morisato, D. and Anderson, K. V (1994). A processed form of the Spätzle protein defines dorsal-ventral polarity in the Drosophila embryo. Development 120, 1243-1250.
27. Smith, C. L. and DeLotto, R. (1994). Ventralizing signal determined by protease activation in Drosophila embryogenesis. Nature 368, 548-551.
28. Smith, C. L., Giordano, H. and DeLotto, R. (1994). Mutational analysis of the Drosophila snake protease: an essential role for domains within the proenzyme polypeptide chain. Genetics 136, 1355-1365.
29. Smith, C. L., Giordano, H., Schwartz, M. and DeLotto, R. (1995). Spatial regulation of Drosophila snake protease activity in the generation of dorsal-ventral polarity. Development 121, 4127-4135.
30. Stein, D., Roth, S., and Nüsslein-Volhard, C. (1991). The polarity of the dorsoventral axis of the Drosophila embryo is defined by an extracellular signal. Cell 65, 725-735.
31. Steward, R. (1989). Relocalization of the dorsal protein from the cytoplasm to the nucleus correlates with its function. Cell 59, 1179-1188.
32. Towbin, H., Staehelin, T. and Gordon, J. (1979). Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and applications. Proc. Natl. Acad. Sci. USA 76, 4350-4354.