Comparison of roxithromycin with cefixime in the treatment of adults with community-acquired pneumonia

Journal of Antimicrobial Chemotherapy

Volumn 41, Issue SUPPL. B, 1998, Pages 75-80

  Salvarezza, C R ^a   Mingrone, H ^b   Fachinelli, H ^c   Kijanczuk, S ^d  

^a Clinica del Torax   (Argentina)

^b HOSPITAL F J MUÑIZ   (Argentina)

^c Hospital Ferroviario   (Argentina)

^d UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

CEFIXIME; ROXITHROMYCIN;

ADULT; ANTIBIOTIC THERAPY; ARTICLE; BACTERIUM DETECTION; CLINICAL EXAMINATION; CLINICAL TRIAL; COMMUNICABLE DISEASE; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFICACY; DRUG TOLERABILITY; FEMALE; HAEMOPHILUS INFLUENZAE; HUMAN; MAJOR CLINICAL STUDY; MALE; MORAXELLA CATARRHALIS; PNEUMONIA; RADIODIAGNOSIS; RANDOMIZED CONTROLLED TRIAL; SERODIAGNOSIS; SPUTUM; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PNEUMONIAE;

ADOLESCENT; ADULT; ANTI-BACTERIAL AGENTS; CEFIXIME; CEFOTAXIME; CEPHALOSPORINS; COMMUNITY-ACQUIRED INFECTIONS; FEMALE; HUMANS; MALE; MIDDLE AGED; PNEUMONIA, BACTERIAL; PNEUMONIA, PNEUMOCOCCAL; ROXITHROMYCIN; STREPTOCOCCUS PNEUMONIAE;

EID: 0031923697     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/41.suppl_2.75     Document Type: Article

References (18)

1. Woodhead, M. A., Macfarlane, J. T., McCracken, J. S., Rose, D. H. & Finch, R. G. (1987). Prospective study of the aetiology and outcome of pneumonia in the community. Lancet i, 671-4.
2. Fang, G. D., Fine, M., Orloff, J., Arisumi, D., Yu, V. L., Kapoor, W. et al. (1990). New and emerging etiologies for community acquired pneumonia with implications for therapy. A prospective multicentre study of 359 cases. Medicine 69, 307-16.
3. Fick, R. B. & Reynolds, H. Y. (1983). Changing spectrum of pneumonia - news media creation or clinical reality? American Journal of Medicine 74, 1-8.
4. Pechere, J.-C. & Auckenthaler, R. (1987). In-vitro activity of roxithromycin against respiratory and skin pathogens. Journal of Antimicrobial Chemotherapy 20, Suppl. B, 1-5.
5. Markham, A. & Faulds, A. (1994). Roxithromycin. An update of its antimicrobial activity, pharmacokinetic properties and therapeutic use. Drugs 48, 297-326.
6. Birkett, D. J., Robson, R. A., Grgurinovich, N. & Tonkin, A. (1990). Single oral dose pharmacokinetics of erythromycin and roxithromycin and the effects of chronic dosing. Therapeutic Drug Monitoring 12, 65-71.
7. Rimoldi, R., Mangiarotti, P., De Rose, V., Nonis, A., Bertoletti, R. & Grassi, G. G. (1988). Penetration of roxithromycin into bronchial secretions. British Journal of Clinical Practice 42, Suppl. 55, 74-7.
8. Boccazzi, A. & Langer, M. (1991). Penetration of roxithromycin into bronchial secretions. Chemotherapy 37, 303-9.
9. Campbell, G. D. (1994). Overview of community-acquired pneumonia. Prognosis and clinical features. Medical Clinics of North America 78, 1035-48.
10. Moroni, M., Franzetti, F. & Antinori, S. (1992). Antibiotic therapy in bronchopulmonary infections. Annals of the Italian Medical Interns 7, 86S-93S.
11. Drach, F. S. & Bryant, R. E. (1993). Spotting the pneumococcus in today's pneumonia milieu. Journal of Respiratory Diseases 14, 198-216.
12. Davies, B. I. & Maeson, F. P. V. (1990). Treatment of Branhamella catarrhalis infections. Journal of Antimicrobial Chemotherapy 25, 1-7.
13. Thom, D. H., Grayston, J. T., Wang, S. P., Kuo, C. C. & Altman, J. (1990). Chlamydia pneumoniae strain TWAR, Mycoplasma pneumoniae, and viral infections in acute respiratory disease in a university student health clinic population. American Journal of Epidemiology 132, 248-56.
14. Karalus, N. C., Garrett, J. E., Lang, S. D. R., Leng, R. A., Kostalas, G. N., Cursons, R. T. M. et al. (1995). Roxithromycin 150 mg b.i.d. versus amoxycillin 500 mg/clavulanic acid 125 mg t.i.d. for the treatment of lower respiratory tract infections in general practice. Infection 23, Suppl. 1, S15-20.
15. Williams, J. D. & Sefton, A. M. (1993). Comparison of macrolide antibiotics. Journal of Antimicrobial Chemotherapy 31, Suppl.C, 11-26.
16. Nilsen, O. G. (1995). Pharmacokinetics of macrolides. Comparison of plasma, tissue and free concentrations with special reference to roxithromycin. Infection 23, Suppl. 1, 5-9.
17. Odenholt-Tornqvist, I., Löwdin, E. & Cars, O. (1995). Postantibiotic effects and postanlibiotic sub-MIC effects of roxithromycin, clarithromycin, and azithromycin on respiratory tract pathogens. Antimicrobial Agents and Chemotherapy 39, 221-6.
18. Gentry, L. O. (1987). Roxithromycin, a new macrolide antibiotic, in the treatment of infections in the lower respiratory tract: an overview. Journal of Antimicrobial Chemotherapy 20, Suppl. B, 145-52.