The primary and final effector mechanisms required for kinin-induced epithelial chloride secretion

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 274, Issue 3 37-3, 1998, Pages

  Cuthbert, Alan W ^a   Huxley, Clare ^b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Cystic fibrosis transmembrane conductance regulator; Kinin B2 receptors; Yeast artificial chromosome

Indexed keywords

BRADYKININ B2 RECEPTOR; CHLORIDE CHANNEL; CHLORIDE ION; KALLIDIN; KININ;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHLORIDE TRANSPORT; CONTROLLED STUDY; CYSTIC FIBROSIS; DIARRHEA; GENE TRANSFER; INTESTINE MUCOSA; MOUSE; NONHUMAN; PRIORITY JOURNAL; YEAST ARTIFICIAL CHROMOSOME;

EID: 0031922792     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.1998.274.3.g578     Document Type: Article

References (30)

1. Anderson, M. P., R. J. Gregory, S. Thompson, D. W. Souza, P. Sucharita, R. C. Mulligan, A. E. Smith, and M. J. Welsh. Demonstration that CFTR is a chloride channel by alteration of its anion selectivity. Science 253: 202-205, 1991.
2. Bear, C. E., C. Li, N. Kartner, R. J. Bridges, T. J. Jenson, M. Ramjeesing, and J. R. Riordan. Purification and functional reconstitution of the cystic fibrosis transmembrane conductance regulator (CFTR). Cell 68: 809-818, 1992.
3. Berschneider, H. M., M. R. Knowles, R. G. Azizkhan, R. C. Boucher, N. A. Tobey, R. C. Orlando, and D. W. Powell. Altered intestinal chloride transport in cystic fibrosis. FASEB J. 10: 2625-2629, 1988.
4. 2 bradykinin receptor gene in mice eliminates bradykinin action on smooth muscle and neurones. J. Biol. Chem. 270: 13706-13710, 1995.
5. 2+. Am. J. Physiol. 264 (Gastrointest. Liver Physiol. 27): G325-G333, 1993.
6. Cuthbert, A. W., C. Egleme, H. Greenwood, M. E. Hickman, S. C. Kirkland, and L. J. MacVinish. Calcium- and cyclic AMP-dependent chloride secretion in human colonic epithelia. Br. J. Pharmacol. 91: 503-515, 1987.
7. Cuthbert, A. W., J. Halstead, R. Ratcliff, W. H. Colledge, and M. J. Evans. The genetic advantage hypothesis in cystic fibrosis: a murine study. J. Physiol. (Lond.) 482: 449-454, 1995.
8. Cuthbert, A. W., P. V. Halushka, D. Kessel, H. S. Margolius, and W. C. Wise. Kinin effects on chloride secretion do not require eicosanoid synthesis. Br. J. Pharmacol. 83: 549-554, 1984.
9. Cuthbert, A. W., P. V. Halushka, H. S. Margolius, and J. S. Spayne. Mediators of the secretory responses to kinins. Br. J. Pharmacol. 82: 597-607, 1984.
10. Cuthbert, A. W., L. J. MacVinish, M. E. Hickman, R. Ratcliff, W. H. Colledge, and M. J. Evans. Ion transporting activity in the murine colonic epithelium of normal and cystic fibrosis animals. Pflug. Arch 428: 508-515, 1994.
11. Cuthbert, A. W., L. J. MacVinish, and R. J. Pickles. Antagonism of kinin effects on epithelia by Hoe 140: apparent competitive and non-competitive interactions. Br. J. Pharmacol. 107: 797-802, 1992.
12. - channel by protein kinase A corrected by insertion of CFTR. Nature 358: 581-584, 1992.
13. Gaginella, T. S., and J. F. Kachur. Kinins as mediators of intestinal secretion. Am. J. Physiol. 256 (Gastrointest. Liver Physiol. 19): G1-G15, 1989.
14. Grubb, B. R. Ion transport across the jejunum in normal and cystic fibrosis mice. Am. J. Physiol. 268 (Gastrointest. Liver Physiol. 31): G505-G513, 1995.
15. Henderson, R. M., M. L. J. Ashford, L. J. MacVinish, and A. W. Cuthbert. Chloride channels and anion fluxes in a human colonic epithelium. Br. J. Pharmacol. 106: 109-114, 1992.
16. Hoult, J. R. S., and J. A. Phillips. Kinin-induced prostaglandin release in rat colon does not display serosal-mucosal "sidedness" after epithelial removal. Br. J. Pharmacol. 88: 3-5, 1986.
17. 2+ interactions affecting epithelial chloride secretion in human cultured colonic epithelia. Br. J. Pharmacol. 108: 462-468, 1993.
18. - secretion in the intestine. Nature 299: 256-259, 1982.
19. Manson, A. L., A. E. O. Trezise, L. J. MacVinish, K. D. Kasschau, N. Birchall, V. Episkopou, G. Vassaux, M. J. Evans, W. H. Colledge, A. W. Cuthbert, and C. Huxley. Complementation of null CF mice with a human CFTR YAC transgene. EMBO J. 16: 4238-4249, 1997.
20. 1 receptors: a review. Immunopharmacology 30: 1-26, 1995.
21. Naclerio, R. M., D. Proud, L. M. Lichtenstein, A. Kagey-Sobotka, J. O. Hendley, J. Sorrentino, and J. M. Gwaltney. Kinins are generated during experimental rhinovirus colds. J. Infect. Dis. 157: 133-142, 1988.
22. 1 receptors in the endothelium from juvenile pig carotid artery (Abstract). Proc. Int. Kinin Symp. 14th Denver 1995, p. L41.
23. Pruneau, D., J. M. Luccarini, E. Defrene, J. L. Paquet, and P. Belichard. Pharmacological evidence for a single bradykinin B2 receptor in the guinea-pig. Br. J. Pharmacol. 116: 2106-2112, 1995.
24. Ratcliff, R., M. J. Evans, A. W. Cuthbert, L. J. MacVinish, D. Foster, J. Anderson, and W. H. Colledge. Production of a severe cystic fibrosis mutation in mice. Nat. Genet. 4: 35-41, 1993.
25. Schweibert, E. M., M. E. Egan, T. Hwang, S. B. Fulmer, S. S. Allen, G. R. Cutting, and W. B. Guggino. CFTR regulates outwardly rectifying chloride channels through an autocrine mechanism involving ATP. Cell 81: 1063-1073, 1995.
26. Sweiry, J. H., and H. J. Binder. Characterisation of aldosterone induced potassium secretion in rat distal colon. J. Clin. Invest. 83: 844-851, 1989.
27. Watson, S., and S. Arkinstall. The G-Protein Linked Receptor, Facts Book. London: Academic, 1994, p. 67-70.
28. + channels in a chloride secreting epithelium. Am. J. Physiol. 244 (Renal Fluid Electrolyte Physiol. 13): F639-F645, 1983.
29. Wolsing, D. H., and J. S. Rosenbaum. Bradykinin stimulated inositol phosphate production in NG108-15 cells is mediated by a small proportion of binding sites which rapidly desensitise. J. Pharmacol. Exp. Ther. 257: 621-633, 1991.
30. Zeitlin, I. J., and A. N. Smith. Mobilisation of tissue kallikrein in inflammatory disease of the colon. Gut 14: 133-138, 1973.