Folate and neural tube defects: Recommendations from a Danish working group

Danish Medical Bulletin

Volumn 45, Issue 2, 1998, Pages 213-217

  Rasmussen, Lone Banke ^a   Andersen, Niels Lyhne ^a   Andersson, Grethe ^a   Lange, Aksel P ^a   Rasmussen, Karsten ^a   Skak Iversen, Lene ^a   Skovby, Flemming ^a   Ovesen, Lars ^a  

^a DANISH VETERINARY AND FOOD ADMINISTRATION   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

HUMAN; MATERNAL NUTRITION; MATERNAL WELFARE; NEURAL TUBE DEFECT; PATIENT COUNSELING; REVIEW; VITAMIN INTAKE;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CHILD; CHILD, PRESCHOOL; DENMARK; DIETARY SUPPLEMENTS; FEMALE; FOLIC ACID; FOOD, FORTIFIED; GESTATIONAL AGE; HUMANS; INCIDENCE; MALE; MIDDLE AGED; NEURAL TUBE DEFECTS; PREGNANCY; RANDOMIZED CONTROLLED TRIALS; RISK FACTORS;

EID: 0031922618     PISSN: 09078916     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (39)

1. Nørgaard-Pedersen B, Bagger P, Bang J, Fischer-Rasmussen W, Gad C, Hasch E et al. Maternal-serum-alphafetoprotein screening for fetal malformations in 28,062 pregnancies. Acta Obstet Gynecol Scand 1985; 64: 511-4.
2. Haase J, Green A, Hauge M, Holm NV, Mathiasen H. A cohort study of neural tube defects (NTD) in Denmark covering the first seven years of life. Childs Nerv Syst 1987; 3: 117-20.
3. Jacobsen P. Regional variations in neural tube defects and alfa-fetoprotein screening in Denmark. Acta Obstet Gynecol Scand 1996; 75: 620-3.
4. Andersen NL, Fagt S, Groth MV, Hartkopp HB, Møller A, Ovesen L et al. Danskernes kostvaner 1995. Publikation nr. 235. København: Levnedsmiddelstyrelsen, 1996.
5. Sandström B, Aro A, Becker W, Lyhne N, Pedersen JI, Pórsdóttir I, Nordiske näringsrekommendationer 1996. København: Nordisk Ministerråd, Nordisk Forlagshus, Nord 1996; 28.
6. Sauberlich HE, Kretsch MJ, Skala JH, Johnson HL, Taylor PC. Folate requirement and metabolism in nonpregnam women. Am J Clin Nutr 1987; 46: 1016-28.
7. Gregory JF. Bioavailability of folate. Eur J Clin Nutr 1997; 51 (suppl 1): S54-9.
8. Steegers-Theunissen RP. Folate metabolism and neural tube defects: a review. Eur J Obstet Gynecol Reprod Biol 1995; 61: 39-48.
9. MRC Vitamin Study Research Group. Prevention of neural tube defects; results of the Medical Research Council Vitamin Study. Lancet 1991; 338: 131-7.
10. Czeizel AE, Dudás I. Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation. N Engl J Med 1992; 327: 1832-5.
11. Kirke PN, Molloy AM, Daly LE, Burke H, Weir DG, Scott JM. Maternal plasma folate and vitamin B12 are independent risk factors for neural tube defects. Q J Med 1993; 86: 703-8.
12. Daly LE, Kirke PN, Molloy A, Weir DG, Scott JM. Folate levels and neural tube defects. Implication for prevention. JAMA 1995; 274: 1698-702.
13. Mills JL, McPartlin JM, Kirke PN, Lee YJ, Conley MR, Weir DG et al. Homocysteine metabolism in pregnancies complicated by neural tube defects. Lancet 1995; 345: 149-51.
14. Steegers-Theunissen RP, Boers GH, Blom HJ, Nijhuis JG, Thomas CM, Borm GF et al. Neural tube defects and elevated homocysteine levels in amniotic fluid. Am J Obstet Gynecol 1995; 172: 1436-41.
15. Friel JK, Frecker M, Fraser FC. Nutritional patterns of mothers of children with neural tube defects in Newfoundland. Am J Med Genet 1995; 55: 195-9.
16. Laurence KM, James N, Miller M, Campbell H. Increased risk of recurrence of pregnancies complicated by fetal neural tube defects in mothers receiving poor diets, and possible benefit of dietary counselling. BMJ 1980; 281: 1592-4.
17. Shaw GM, Velie EM, Schaffer D. Risk of neural tube defect-affected pregnancies among obese women. JAMA 1996; 275; 1093-6.
18. Werler MM, Louik C, Shapiro S, Mitchell AA. Prepregnant weight in relation to risk of neural tube defects. JAMA 1996; 275: 1089-92.
19. Holmes LB. Spina bifida: anticonvulsants and other maternal influences. Ciba Foundation Symposium 181. Neural tube defects. Chiehester: John Wiley & Sons, 1994: 232-44.
20. Dickinson CJ, Does folic acid harm people with vitamin B12 deficiency? Q J Med 1995; 88: 357-64.
21. Nexø E, Hansen M, Rasmussen K, Lindgren A, Gräsbeck R. How to diagnose cobalamin deficiency. Scand J Clin Lab Invest 1994; 54 (suppl 219): 61-76.
22. Sheeny TW. Folic acid: lack of toxicity. Lancet 1973; I: 37.
23. Jennings E. Folic acid as a cancer-preventing agent. Med Hypotheses 1995; 45: 297-303.
24. Rosen F, Nichol CA. Inhibition of the growth of an amethopterin-refractory tumor by dietary restriction of folic acid. Cancer Res 1962; 22: 495-500.
25. Childers JM, Chu J, Voigt L, Feigl P, Tamimi HK, Franklin EW et al. Chemo prevention of cervical cancer with folic acid: a phase III Southwest Oncology Group study. Cancer Epidemiol Biomark Prev 1995; 4: 155-9.
26. Stampfer MJ, Malinow MR. Can lowering homocysteine levels reduced cardiovascular risk? N Engl J Med 1995; 332: 328-9.
27. Ubbink JB, Vermaak WJH, Merwe A, Becker PJ, Delport R, Potgieter HC. Vitamin requirements for the treatment of hyperhomocysteinemia in humans. J Nutr 1994; 124: 1927-33.
28. Eto I, Krumdieck CL. Role of vitamin B12 and folate deficiencies in carcinogenesis, Adv Exp Med Biol 1986; 206: 313-30.
29. Heimburger DC. Localized deficiencies of folic acid in aerodigestive tissues. Ann NY Acad Sci 1992: 87-93.
30. Mason JB. Folate and colonic carcinogenesis: searching for a mechanistic understanding. J Nutr Biochem 1994; 5: 170-5.
31. Butterworth CE, Hatch KD, Macaluso M, Cole P, Sauberlic HE, Soong S et al. Folate deficiency and cervical dysplasia. JAMA 1992; 267: 528-33.
32. Ferraroni M, La Vecchia C. D'Avanzo B, Negri E, Franceschi S, Decarli A. Selected micronutrient intake and risk of colorectal cancer. Br J Cancer 1994; 70: 1150-5.
33. Giovannucci E, Rimm EB, Ascherio EB, Stampfer MJ, Colditz G, Willett WC. Alcohol, low-methionine-low-folate diets, and risk of colon cancer in men. J Natl Cancer Inst 1995; 87: 265-73.
34. Holmes-Siedle M, Dennis J, Lindenbaum RH, Galliard A. Long term effects of periconceptional multivitamin supplements for prevention of neural tube defects: a seven to 10 year follow up. Arch Dis Child 1992; 67: 1436-41.
35. Scholl TO, Hediger ML, Schall JI, Khoo C, Fischer RL. Dietary and serum folate: their influence on the outcome of pregnancy. Am J Clin Nutr 1996; 63: 520-5.
36. Rothman KJ, Moore LL, Singer MR, Nguyen UDT, Mannino S, Milunsky A. Teratogenicity of high vitamin A intake. N Engl J Med 1995; 333: 1369-73.
37. Hine RJ. What practitioners need to know about folic acid. J Am Diet Assoc 1996; 96: 451-2.
38. Clark NAC, Fisk NM. Minimal compliance with the Department of Health recommendation for routine folate prophylaxis to prevent fetal neural tube defects. Br J Obstet Gynaecol 1994; 101:709-10.
39. Czeizel AE. Nutritional supplementation and prevention of congenital abnormalities. Curr Opin Obstet Gynecol 1995; 7: 88-94.