The 3' part of the immunoglobulin χ locus of the mouse

European Journal of Immunology

Volumn 28, Issue 5, 1998, Pages 1458-1466

  Kirschbaum, Thomas ^a   Pourrajabi, Soheil ^a   Zocher, Ines ^a   Schwendinger, Jürgen ^a   Heim, Verena ^a   Röschenthaler, Franz ^a   Kirschbaum, Verena ^a   Zachau, Hans G ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

Contig; Immunoglobulin V genes; Mouse

Indexed keywords

ARTICLE; COSMID; GENE LOCUS; GENE REARRANGEMENT; IMMUNOGLOBULIN GENE; MOLECULAR CLONING; PRIORITY JOURNAL; YEAST ARTIFICIAL CHROMOSOME;

EID: 0031922445     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-4141(199805)28:05<1458::AID-IMMU1458>3.0.CO;2-5     Document Type: Article

References (40)

1. Kofler, R., Geley, S., Kofler, H. and Helmberg, A., Mouse variable-region gene families: complexity, polymorphism and use in non-autoimmune responses. Immunol. Rev. 1992. 128: 1-17.
2. Max, E. E., Immunoglobulins. Molecular Genetics, In Paul, W. (Ed.). Fundamental Immunology, 3rd Edn. Raven Press, New York 1993, pp 315-382.
3. Zocher, I., Röschenthaler, F., Kirschbaum, T., Schäble, K. F., Hörlein, R., Fleischmann, B., Kofler, R., Geley, S., Hameister, H. and Zachau, H. G., Clustered and interspersed gene families in the mouse immunoglobulin (greek small letter script kappa) locus. Eur. J. Immunol. 1995. 25: 3326-3331.
4. Kirschbaum, T., Jaenichen, R. and Zachau, H. G., The mouse immunoglobulin (greek small letter script kappa) locus contains about 140 variable gene segments. Eur. J. Immunol. 1996. 26: 1613-1620.
5. George, J. B., Li, S. and Garrard, W. T., Yeast artificial chromosome contigs reveal that distal variable-region genes reside at least 3 megabases from the joining regions in the murine immunoglobulin (greek small letter script kappa). locus. Proc. Natl. Acad. Sci. USA 1995. 92: 12421-12425.
6. Schupp, I. W., Schlake, T., Kirschbaum, T., Zachau, H. G. and Boehm, T., A yeast artificial chromosome contig spanning the mouse immunoglobulin kappa light chain locus. Immunogenetics 1997. 45: 180-187.
7. George, J. B., Li, S. and Garrard, W. T., The murine immunoglobulin kappa locus: new insights into genome organisation and expression. In Capra, J. D. and Zanetti, M. (Eds.) The Antibodies Vol. 4. Gordon and Breach/Hardwood Academic Publishers, San Diego 1998, in press.
8. Shizuya, H., Birren, B., Kim, U.-J., Mancino, V., Slepak, T., Tachiiri, Y. and Simon, M., Cloning and stable maintenance of 300-kilobase-pair fragments of human DNA in Escherichia coli using an F-factor-based vector. Proc. Natl. Acad. Sci. USA 1992. 89: 8794-8797.
9. Venter, J. C., Smith, H. O. and Hood, L., A new strategy for genome sequencing. Nature 1996. 381: 364-366.
10. Zachau, H. G., The human immunoglobulin (greek small letter script kappa) genes. In Honjo, T. and Alt, F. W. (Eds.) Immunoglobulin Genes, 2nd Edn. Academic Press, London 1995, pp 173-191.
11. Weigert, M., Gatmaitan, L., Loh, E., Schilling, J. and Hood, L., Rearrangement of genetic information may produce immunoglobulin diversity. Nature 1978. 276: 785-790.
12. Cory, S., Tyler, B. M. and Adams, J. M., Sets of immunoglobulin V kappa genes homologous to ten cloned V kappa sequences: implications for the number of germ-line V kappa genes. J. Mol. Appl. Genet. 1982. 1: 103-116.
13. Heinrich, G., Traunecker, A. and Tonegawa, S., Somatic mutation creates diversity in the major group of mouse immunoglobulin (greek small letter script kappa) light chains. J. Exp. Med. 1984. 159:417-435.
14. Alanen, A. and Weiss, S., Sequence and linkage of the V(greek small letter script kappa)21A and G germ-line gene segments in the mouse. Eur. J. Immunol. 1989. 19: 1961-1963.
15. D'Hoostelaere, L. A., Huppi, K., Mock, B., Mallett, C. and Potter, M., The Ig (greek small letter script kappa) L chain allelic groups among the Ig (greek small letter script kappa) haplotypes and Ig (greek small letter script kappa) crossover populations suggest a gene order. J. Immunol. 1988. 141: 652-661.
16. Zimmerer, E. J. and Passmore, H. C., Structural and genetic properties of the EB recombinational hotspot in the mouse. Immunogenetics 1991. 33: 132-140.
17. Harada, K. and Yamagishi, H., Lack of feedback inhibition of V(greek small letter script kappa) gene rearrangement by productively rearranged alleles. J. Exp. Med. 1991. 173: 409-415.
18. Seidman, J. G., Nau, M. M., Norman, B., Kwan, S.-P., Scharff, M. and Leder, P., Immunoglobulin V/J recombination is accompanied by deletion of joining site and variable region segments. Proc. Natl. Acad. Sci. USA 1980. 77: 6022-6026.
19. Feddersen, R. M. and Van Ness, B. G., Double recombination of a single immunoglobulin (greek small letter script kappa)-chain allele: implications for the mechanism of rearrangement. Proc. Natl. Acad. Sci. USA 1985. 82: 4793-4797.
20. Hoechtl, J. and Zachau, H. G., A novel type of aberrant recombination in immunoglobulin genes and its implications for V-J joining mechanism. Nature 1983. 302: 260-263.
21. Müller, B., Stappert, H. and Reth, M., A physical map and analysis of the murine C kappa-RS region show the presence of a conserved element. Eur. J. Immunol. 1990. 20: 1409-1411.
22. Kroemer, G., Helmberg, A., Bernot, A., Auffray, C. and Kofler, R., Evolutionary relationship between human and mouse immunoglobulin kappa light chain variable region genes, Immunogenetics 1991. 33: 42-49.
23. Shefner, R., Mayer, R., Kaushik, A., D'Eustachio, P., Bona, C. and Diamond, B., Identification of a new V(greek small letter script kappa) gene family that is highly expressed in hybridomas from an autoimmune strain. J. Immunol. 1990. 145: 1609-1614.
24. Barnes, W. M., PCR amplification of up to 35-kb DNA with high fidelity and high yield from lambda bacteriophage templates. Proc. Natl. Acad. Sci. USA 1994. 91: 2216-2220.
25. Hawley, R. G., Shulman, M. J., Murialdo, H., Gibson, D. M. and Hozumi, N., Mutant immunoglobulin genes have repetitive DNA elements inserted into their intervening sequences. Proc. Natl. Acad. Sci. USA 1982. 79: 7425-7429.
26. Shlomchik, M. J., Marshak-Rothstein, A., Wolfowicz, C. B., Rothstein, T. L. and Weigert, M. G., The role of clonal selection and somatic mutation in autoimmunity. Nature 1987. 328: 805-811.
27. Co, M. S., Avdalovic, N. M., Caron, P. C., Avdalovic, M. V., Scheinberg, D. A. and Queen, C., Chimeric and humanized antibodies with specificity for the CD33 antigen. J. Immunol. 1992. 148: 1149-1154.
28. Weissenhorn, W., Chen, Y.-H., Reiter, C., Federle, C., Weiss, E. H., Riethmüller, G. and Rieber, E. P., Structural diversity of monoclonal CD4 antibodies and their capacity to block the HIV gp120/CD4 interaction. Hybridoma 1996. 15: 117-124.
29. Ibrahim, S. M., Weigert, M. Basu, C., Erikson, J. and Radic, M. Z., Light chain contribution to specificity in anti-DNA antibodies. J. Immunol. 1995. 155: 3223-3233.
30. Clarke, S. H., Huppi, K., Ruezinsky, D., Staudt, L., Gerhard, W. and Weigert, M., Inter- and intraclonal diversity in the antibody response to influenza hemagglutinin. J. Exp. Med. 1985. 161: 687-704.
31. 1 mice. J. Exp. Med. 1992. 176: 761-779.
32. Misplon, J. A., Wood, T., Harvath, L. and Epstein, S. L., Antibody repertoire in the response to a protein antigen. J. Immunol. 1994. 152: 2778-2787.
33. S mice. J. Immunol. 1994. 152: 667-675.
34. Lawler, A. M., Kearney, J. F., Kuehl, M. and Gearhart, P. J., Early rearrangements of genes encoding murine immunoglobulin (greek small letter script kappa) chains, unlike genes encoding heavy chains, use variable gene segments dispersed throughout the locus. Proc. Natl. Acad. Sci. USA 1989. 86: 6744-6747.
35. Sherman, M. A., Deans, R. J. and Bölger, M. B., Haloperidol binding to monoclonal antibodies. J. Biol. Chem. 1988. 263: 4059-4063.
36. Clarke, S. and McCray, S., A shared (greek small letter script kappa) reciprocal fragment and a high frequency of secondary J(greek small letter script kappa)5 rearrangements among influenza hemagglutinin specific B cell hybridomas. J. Immunol. 1991. 146: 343-349.
37. Kavaler, J., Caton, A. J., Staudt, L. M., Schwartz, D. and Gerhard, W., A set of closely related antibodies dominates the primary antibody response to the antigenic site CB of the A/PR/8/34 influenza virus hemagglutinin. J. Immunol. 1990. 145: 2312-2321.
38. Clarke, S. H., Staudt, L. M., Kavaler, J., Schwartz, D., Gerhard, W. U. and Weigert, M. G., V region gene usage and somatic mutation in the primary and secondary responses to influenza virus hemagglutinin. J. Immunol. 1990. 144: 2795-2801.
39. Diaw, L., Magnac, C., Pritsch, O., Buckle, M., Alzari, P. M. and Dighiero, G., Structural and affinity studies of IgM polyreactive natural antibodies. J. Immunol. 1997. 158: 968-976.
40. Apel, T. W., Scherer, A., Adachi, T., Auch, D., Ayane, M. and Reth, M., The ribose 5-phosphate isomerase-encoding gene is located immediately downstream from that encoding murine immunoglobulin (greek small letter script kappa). Gene 1995. 156: 191-197.