Datin, a yeast poly(dA:DT)-binding protein, behaves as an activator of the wild-type ILV1 promoter and interacts synergistically with Reb1p

Molecular and General Genetics

Volumn 258, Issue 1-2, 1998, Pages 95-103

  Moreira, J M A ^a   Remacle, J E ^b,c   Kielland Brandt, M C ^b   Holmberg, S ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b CARLSBERG LABORATORY   (Denmark)

^c UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Basal transcriptional activation; Eukaryotic promoters; Gene regulation; Poly(dA:dT)

Indexed keywords

DATIN; DNA BINDING PROTEIN; NUCLEOTIDE BINDING PROTEIN; POLY(DEOXYADENYLATE DEOXYTHYMIDYLATE); TRANS ACTING FACTOR; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CONTROLLED STUDY; GENE ACTIVATION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PROTEIN INTERACTION; STRUCTURAL GENE; TRANSCRIPTION REGULATION; YEAST;

BASE SEQUENCE; DNA-BINDING PROTEINS; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; FUNGAL PROTEINS; GENE EXPRESSION REGULATION; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; POLY DA-DT; PROMOTER REGIONS (GENETICS); SACCHAROMYCES CEREVISIAE PROTEINS; THREONINE DEHYDRATASE;

EUKARYOTA;

EID: 0031922423     PISSN: 00268925     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004380050711     Document Type: Article

References (37)

1. Alexeev DG, Lipanov AA, Skuratovskii IY (1987) Poly (dA) poly(dT) is a B-type double helix with a distinctively narrow minor groove. Nature 325:821-823
2. Amann E, Brosius J (1985) 'ATG vectors' for regulated high-level expression of cloned genes in Escherichia coli. Gene 40:183-190
3. Arndt KT, Fink GR (1986) GCN4 protein, a positive transcription factor in yeast binds general control promoters at all 5′-TGACTC-3′ sequences. Proc Natl Acad Sci USA 83:8516-8520
4. Ausubel FM, Brent R, Kingston RE, Moore DD, Smith JA, Seidmann JG, Struhl K (eds) (1987) Current protocols in molecular biology. Wiley-Interscience, New York
5. Behe MJ (1995) An overabundance of long oligopurine tracts occurs in the genomes of simple and complex eukaryotes. Nucleic Acids Res 23:689-695
6. Brandi CJ, Struhl K (1990) A nucleosome-positioning sequence is required for GCN4 to activate transcription in the absence of a TATA element. Mol Cell Biol 10:4256-4265
7. Brandi CJ, Martens JA, Liaw PC-Y, Furlanetto AM, Wobbe CR (1992) TATA-binding protein activates transcription when upstream of a GCN4-binding site in a novel yeast promoter. J Biol Chem 267:20943-20952
8. Buchman AR, Kornberg RD (1990) A yeast ARS-binding protein activates transcription synergistically in combination with other weak activating factors. Mol Cell Biol 10:887-897
9. G and functions as a powerful auxiliary gene activator. Genes Dev 4:503-514
10. Chen W, Tabor S, Struhl K (1987) Distinguishing between mechanisms of eukaryotic transcriptional activation with bacteriophage T7 RNA polymerase. Cell 50:1047-1055
11. Dammann R, Lucchini R, Koller T, Sogo JM (1993) Chromatin structures and transcription of rDNA in yeast Saccharomyces cerevisiae. Nucleic Acids Res 21:2331-2338
12. Fedor MJ, Lue NF, Kornberg RD (1988) Statistical positioning of nucleosomes by specific protein-binding to an upstream activating sequence in yeast. J Mol Biol 204:109-127
13. Graham IR, Chambers A (1994) A Reblp-binding site is required for efficient activation of the yeast RAP1 gene, but multiple binding sites for Raplp are not essential. Mol Microbiol 12:931-940
14. Guarente L, Ptashne M (1981) Fusion of Escherichia coli lacZ to the cytochrome c gene of Saccharomyces cerevisiae. Proc Natl Acad Sci USA 78: 2199-2203
15. Holmberg S, Petersen JGL (1988) Regulation of isoleucine-valine biosynthesis in Saccharomyces cerevisiae. Curr Genet 13:207-217
16. Ito H, Fukuda Y, Murata K, Kimura A (1983) Transformation of intact yeast cells treated with alkali cations. J Bacteriol 153:163-168
17. Iyer V, Struhl K (1995) Poly(dA:dT), a ubiquitous promoter element that stimulates transcription via its intrinsic DNA structure. EMBO J 14:2570-2579
18. Ju Q, Morrow BE, Warner JR (1990) REB1, a yeast DNA-binding protein with many targets, is essential for cell growth and bears some resemblance to the oncogene myb. Mol Cell Biol 10:5226-5234
19. Lang WH, Reeder RH (1993) The REB1 site is an essential component of a terminator for RNA polymerase I in Saccharomyces cerevisiae. Mol Cell Biol 13:649-658
20. Liaw PCY, Brandl CJ (1994) Denning the sequence specificity of the Saccharomyces cerevisiae DNA binding protein REB1p by selecting binding sites from random-sequence oligonucleotides. Yeast 10:771-787
21. Losa R, Omari S, Thoma F (1990) Poly(dA)-poly(dT)-rich sequences are not sufficient to exclude nucleosome formation in a constitutive yeast promoter. Nucleic Acids Res 18:3495-3502
22. Lue NF, Buchman AR, Kornberg RD (1989) Activation of yeast RNA polymerase II transcription by a thymidine-rich upstream element in vitro. Proc Natl Acad Sci USA 86:486-490
23. Maniatis T, Fritsch EF, Sambrook J (1982) Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York
24. Miller JH (1972) Experiments in molecular genetics. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York
25. Miozzari G, Niederberger P, Hütter R (1978) Tryptophan biosynthesis in Saccharomyces cerevisae: control of the flux through the pathway. J Bacteriol 134:48-59
26. Morrow BE, Johnson SP, Warner JR (1989) Proteins that bind to the yeast rDNA enhancer. J Biol Chem 264:9061-9068
27. Morrow BE, Johnson SP, Warner JR (1993) The rRNA enhancer regulates rRNA transcription in Saccharomyces cerevisiae. Mol Cell Biol 13:1283-1289
28. Nelson HCM, Finch JT, Luisi BF, Klug A (1987) The structure of an oligo(dA)-oligo(dT) tract and its biological implications. Nature 330:221-226
29. Reardon BJ, Winters RS, Gordon D, Winter E (1993) A peptide motif that recognizes A-T tracts in DNA. Proc Natl Acad Sci USA 90:11327-11331
30. Reardon BJ, Gordon D, Ballard MJ, Winter E (1995) DNA binding properties of the Saccharomyces cerevisiae DAT1 gene product. Nucleic Acids Res 23:4900-4906
31. Remade JE, Holmberg S (1992) A REB1-binding site is required for GCN4-independent ILV1 basal level transcription and can be functionally replaced by an ABF1-binding site. Mol Cell Biol 12:5516-5526
32. Sarkar G, Sommer SS (1990) The "megaprimer" method of sitedirected mutagenesis. Biotechniques 8:404-407
33. Scott EW, Baker HV (1993) Concerted action of the transcriptional activators REB1, RAB1, and GCR1 in the high-level expression of the glycolytic gene TPI. Mol Cell Biol 13:543-550
34. Struhl K (1985) Naturally occurring poly(dA-dT) sequences are upstream promoter elements for constitutive transcription in yeast. Proc Natl Acad Sci USA 82:8419-8423
35. Thiry-Blaise LM, Loppes R (1990) Deletion analysis of the ARG4 promoter of Saccharomyces cerevisiae: a poly(dA-dT) stretch involved in gene transcription. Mol Gen Genet 223:474-480
36. Wang H, Nicholson PR, Stillman DJ (1990) Identification of a Saccharomyces cerevisiae DNA-binding protein involved in transcriptional regulation. Mol Cell Biol 10:1743-1753
37. Winter E, Varshavsky A (1989) A DNA binding protein that recognizes oligo(dA)-oligo(dT) tracts. EMBO J 8:1867-1877