Protection against developmental deficiencies by a lipophilic VIP analogue

Neurochemical Research

Volumn 23, Issue 5, 1998, Pages 689-693

  Gozes, Illana ^a   Bachar, Michal ^a   Bardea, Amos ^a   Davidson, Ariane ^a   Rubinraut, Sara ^b   Fridkin, Mati ^b  

^a TEL AVIV UNIVERSITY   (Israel)

^b WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Cholinergic blockade; Developmental milestones; Hypoxia; Learning and memory; Vasoactive intestinal peptide

Indexed keywords

ETHYLCHOLINE MUSTARD AZIRIDINIUM; STEARYL NLE VASOACTIVE INTESTINAL POLYPEPTIDE; UNCLASSIFIED DRUG; VASOACTIVE INTESTINAL POLYPEPTIDE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHOLINERGIC RECEPTOR BLOCKING; COGNITION; CONTROLLED STUDY; DEVELOPMENTAL DISORDER; GROWTH RETARDATION; HYPOXIA; LEARNING; MAZE TEST; NEUROPROTECTION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; SPATIAL MEMORY;

AGING; ANIMALS; ANOXIA; AZIRIDINES; CHOLINE; MALE; MAZE LEARNING; MEMORY; MENTAL RETARDATION; NEUROMUSCULAR BLOCKING AGENTS; NEUROTOXINS; RATS; SPACE PERCEPTION; VASOACTIVE INTESTINAL PEPTIDE;

EID: 0031921669     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1022494907001     Document Type: Article

References (35)

1. Said, S. I., and Mutt, V. 1970. Polypeptide with broad biological activity: isolation from small intestine. Science 169:1217-1218.
2. Cottrell, G. A., Veldhuis, H. D., Rostene, W. H., and De Kloet, E. R. 1984. Behavioral actions of vasoactive intestinal peptide (VIP). Neuropeptides 4:331-341.
3. Flood, J. F., Garland, J. S., and Morley, J. E. 1990. Vasoactive intestinal peptide (VIP): an amnestic neuropeptide. Peptides 11: 933-938.
4. Glowa, J. R., Panlilio, L. V., Brenneman, D. E., Gozes, I., Fridkin, M., and Hill, J. M. 1992. Learning impairment following intracerebral administration of the HIV envelope protein gp120 or a VIP antagonist. Brain Res. 570:49-53.
5. Gozes, I., Glowa, J., Brenneman, D. E., McCune, S. K., Lee, E., and Westphal, H. 1993. Learning and sexual deficiencies in transgenic mice carrying a chimeric vasoactive intestinal peptide gene. J. Mol. Neurosci. 4:185-193.
6. Gozes, I., Bardea, A., Reshef, A., Zamostiano, R., Zhukovsky, S., Rubinraut, S., Fridkin, M., and Brenneman, D. E. 1996. Novel Neuroprotective strategy for Alzheimer's disease: inhalation of a fatty neuropeptide. Proc. Natl. Acad. Sci. USA. 93:427-432.
7. Takashima, A., Maeda, Y., and Itoh, S. 1993. Influence of chronic intracerebroventricular infusion of vasoactive intestinal peptide (VIP) on memory processes in Morris water pool test in the rat. Peptides 14:1073-1078.
8. Yamaguchi, Y., and Kobayashi, H. 1994. Effects of vasoactive intestinal peptide (VIP) on scopolamine-induced amnesia in the rat. Neuropeptides 26:153-158.
9. Gozes, I., Meltzer, E., Rubinraut, S., Brenneman, D. E., and Fridkin, M. 1989. Vasoactive intestinal peptide potentiate sexual behavior: Inhibition by novel antagonist. Endocrinology 125:2945-2949.
10. Gressens, P., Hill, J. M., Paindaveine, B., Gozes, I., Fridkin, M., and Brenneman, D. E. 1994. Severe microcephaly induced by blockade of vasoactive intestinal peptide function in the primitive neuroepithelium of the mouse. J. Clin. Invest. 94:2020-2027.
11. Hill, J. M., Mervis, R. F., Politi, J., McCune, S. K., Gozes, I., Fridkin, M., and Brenneman, D. E. 1994. Blockade of VIP during neonatal development induces neuronal damage and increases VIP and VIP receptors in brain. Ann. N.Y. Acad. Sci. 739:211-225
12. Hill, J. M., Gozes, I., Hill, J. L., Fridkin, M., and Brenneman, D. E. 1991. Vasoactive intestinal peptide antagonist retards the development of neonatal behaviors in the rat. Peptides. 12:187-192.
13. Gozes, I., Lilling, G., Glazer, R., Ticher, A., Ashkenazi, I. E., Davidson, A., Rubinraut, S., Fridkin, M., and Brenneman, D. E. 1995. Superactive lipophilic peptides discriminate multiple VIP receptors. J. Pharmacol. Exper. Therap. 273:161-167.
14. Fatatis, A., Holtzclaw, L. A., Avidor, R., Brenneman, D. E., and Russell, J. T. 1994. VIP increases intracellular calcium in astroglia: synergism with alpha-adrenergic receptors. Proc. Natl. Acad. Sci. USA. 91:2036-2040.
15. Chik, C. L., Young, I., and Ho, A. K. 1991. Differential involvement of the arachidonic acid cascade on the alpha 1-adrenergic potentiation of vasoactive intestinal peptide-versus beta-adrenergic-stimulated cyclic AMP and cyclic GMP accumulation in rat pinealocytes. J. Neurochem. 57:1534-1539.
16. Magistretti, P. J., Sorg, O., Yu, N., Martin, J. L., and Pellerin, L. 1993. Neurotransmitters regulate energy metabolism in astrocytes: implications for the metabolic trafficking between neural cells. Dev. Neurosci. 15:306-312.
17. Brenneman, D. E., Eiden, L. E., and Siegel, R. E. 1985. Neuropeptide regulation of neuronal development in spinal cord cultures. Peptides 6:35-39.
18. Masuo, Y., Matsumoto, Y., Tokito, F., Tsuda, M., and Fujino, M. 1993. Effects of vasoactive intestinal polypeptide (VIP) and pituitary adenylate cyclase activating polypeptide (PACAP) on the spontaneous release of acetylcholine from the rat hippocampus by brain microdialysis. Brain Res. 611:207-215.
19. Gozes, I., Reshef, A., Salah, D., Rubinraut, S., and Fridkin, M. 1994. Stearyl-Norleucine-VIP a novel VIP analogue for noninvasive impotence treatment. Endocrinology. 134:2121-2125.
20. Speiser, Z., Amitzi-Zonder, J., Ashkenazi, R., Giter, S., and Cohen, S. 1990. Central catecholaminergic dysfunction and behavioral disorders following hypoxia in adult rats. Behav. Brain Res. 37:19-27.
21. Armstrong, J. N., and Pappas, B. A. 1991. The histopathological, behavioral and neurochemical effect of ethylcholine mustard aziridinum (AF64A) in the neonatal rat. Develop. Brain Res. 61:249-257.
22. Fisher, A., Brandeis, R., Pittel, Z., Karton, I., Sapir, M., Dachir, S., Levy, A., and Heldman, E. 1989. (+-)-cis-2-methyl-spiro (1.3-oxathiolane 5.3′) quinuclidine (AF102B): a new M1 agonist attenuates cognitive dysfunction in AF64A-treated rats. Neurosci. Lett. 102:325-331.
23. Moos, W. H., Davis, R. E., and Schwartz, R. D. 1989. A simplified procedure for preparing the cholinergic neurotoxin Ethyl- 1 - (2 -hydroxy ethyl) aziridinium ion (AF64A). Organic Prep. Proc. Int. 21:315.
24. Brenneman, D. E., and Eiden, L. E. 1986. Vasoactive intestinal peptide and electrical activity influence neuronal survival. Proc. Natl. Acad. Sci. USA 83:1159-1162.
25. Gozes, I., and Brenneman, D. E. 1993. Neuropeptides as growth and differentiation factors in general and VIP in particular. J. Mol. Neurosci. 4:1-9.
26. Royston, M. C., Mann, D., Pickering-Brown, S., Owen, F., Perry, R., Raghaven, R., Khin-Nu, C., Tyrer, S., Day, K., and Crook, R. 1994. Apolipoprotein E epsilon 2 allele promotes longevity and protects patients with Down's syndrome from dementia. Neuroreport 5:2583-2585.
27. Gozes, I., Shachter, P., Shani, Y., and Giladi, E. 1988. Vasoactive intestinal peptide gene expression from embryos to aging rats. Neuroendocrinology 47:27-31.
28. Gozes, I., Shani, Y., and Rostene, W. H. 1987. Developmental expression of the VIP-gene in brain and intestine. Mol. Brain Res. 2:137-148.
29. Levy Holtzman, R., Malach, R., and Gozes, I. 1989. Disruption of the optic pathway during development affects vasoactive intestinal peptide mRNA expression. The New Biologist 1:215-221.
30. Agoston, D. V., Eiden, L. E., Brenneman, D. E., and Gozes, I. 1991. Spontaneous electrical activity regulates vasoactive intestinal peptide expression in dissociated spinal cord cell cultures. Mol. Brain Res. 10:235-240.
31. Kashiba, H., Senba, E., Kawai, Y., Ueda, Y., and Tohyama, M. 1992. Axonal blockade induces the expression of vasoactive intestinal polypeptide and galanin in rat dorsal root ganglion neurons. Brain Res. 577:19-28.
32. Glazer, R., and Gozes, I. 1994. Diurnal oscillation in vasoactive intestinal peptide gene expression independent of environmental light entraining. Brain Res. 644:164-168.
33. Brenneman, D. E., Gozes, I. A femtomolar-acting neuroprotective peptide. J. Clin. Invest. 97:2299-2307; 1996.
34. Said, S. I. Molecules that protect: The defense of neurons and other cells. J. Clin. Invest. 97:2163-2164; 1996.
35. Wurtman, R. J., Corkin, S., and Growdon, J. H. 1996. The Neurobiology of Alzheimer's disease. Ann NY Acad. Sci. 777, 1-439.