Lithium during pregnancy: Drug effects and their therapeutic implications

CNS Drugs

Volumn 9, Issue 4, 1998, Pages 261-269

  Yonkers, Kimberly A ^a,b   Little, Bertis B ^a   March, Dana ^a,b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LITHIUM;

ANIMAL MODEL; ARTICLE; BREAST FEEDING; CHEMICAL TERATOGENESIS; CLINICAL TRIAL; CONGENITAL HEART MALFORMATION; CONTROLLED STUDY; DRUG EFFECT; EBSTEIN ANOMALY; EMBRYO DEVELOPMENT; FEMALE; FETUS DEVELOPMENT; HUMAN; MAJOR CLINICAL STUDY; MANIC DEPRESSIVE PSYCHOSIS; MOUSE; NONHUMAN; PERINATAL DRUG EXPOSURE; POSTNATAL DEVELOPMENT; PRACTICE GUIDELINE; PRIORITY JOURNAL; RAT; RISK BENEFIT ANALYSIS; TOXICITY TESTING;

EID: 0031920796     PISSN: 11727047     EISSN: None     Source Type: Journal    
DOI: 10.2165/00023210-199809040-00002     Document Type: Article

References (59)

1. Goodwin FK, Jamison KR. Manic depressive illness. New York: Oxford University Press, Inc., 1990
2. Guscott R, Taylor L. Lithium prophylaxis in recurrent affective illness: efficacy, effectiveness and efficiency. Br J Psychiatry 1994; 164: 741-6
3. Rybakowski J. Chlopocka-Wozniak M, Kapelski Z, et al. The relative prophylactic efficacy of lithium against manic and depressive recurrences in bipolar patients. Int Pharmacopsychiatry 1980; 15: 86-90
4. Peselow ED, Fieve RR, Difiglia C, et al. Lithium prophylaxis of bipolar illness. The value of combination treatment. BMJ 1994; 164: 208-14
5. Suppes T, Baldessarini RJ, Faedda GL, et al. Risk of recurrence following discontinuation of lithium treatment in bipolar disorder. Arch Gen Psychiatry 1991; 48: 1082-8
6. Robins LN, Helzer JE, Weissman MM, et al. Lifetime prevalence of specific disorders in three sites. Arch Gen Psychiatry 1984; 41: 949-58
7. Kessler RC, McGonagle KA, Zhao S, et al. Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States. Results from the National Comorbidity Survey. Arch Gen Psychiatry 1994; 51: 8-19
8. Smithberg M, Dixit PK. Teratogenic effects of lithium in mice. Teratology 1982; 26: 239-46
9. Johansen K, Ulrich K. Preliminary studies of the possible teratogenic effect of lithium. Acta Psychiatr Scand 1969; 207 Suppl.: 91-5
10. Trautner EM, Pennycuik PR, Morris RJH, et al. The effects of prolonged sub-toxic lithium ingestion on pregnancy in rats. Aust J Exp Biol 1958; 36: 305-22
11. Gralla EJ, Mellhenny HM. Studies in pregnant rats, rabbits and monkeys with lithium carbonate. Toxicol Appl Pharmacol 1972; 21: 428-33
12. Marathe MR, Thomas GP. Embryotoxicity and teratogenicity of lithium carbonate in Wistar rat. Toxicol Lett 1986; 34: 115-20
13. Wright TL, Hoffman LH, Davies J. Teratogenic effects of lithium in rats. Teratology 1970; 4: 151-6
14. Johansen KT. Lithium teratogenicity. Lancet 1971 May 15; 1: 1026-7
15. Hansen DK, Walker RC, Grafton TF. Effect of lithium carbonate on mouse and rat embryos in vitro. Teratology 1990; 41: 155-60
16. Schluter G. Effects of lithium carmine and lithium carbonate on the prenatal development of mice. Naunyn Schmiedebergs Arch Pharmacol 1971; 270: 56-64
17. Bass AD, Yntema CL, Hammond WS, et al. Studies on the mechanism by which sulfadiazine affects the survival of the mammalian embryo. J Pharmacol Exp Ther 1950; 101: 362-7
18. Loevy HT. Lithium ion in cleft palate teratogenesis in CD-1 mice (37653). Proc Soc Exp Biol Med 1973; 144: 644-6
19. Szabo KT. Teratogenic effect of lithium carbonate in the fetal mouse. Nature 1970; 225: 73-5
20. Kelley KW, McGlone JJ, Froseth JA. Lithium toxicity in pregnant swine. Proc Soc Exp Biol Med 1978; 158: 123-7
21. Wright TL, Hoffman LH, Davies J. Teratogenic effects of lithium in rats. Teratology 1971; 4: 151-6
22. Goldfield MD, Weinstein MR. Lithium carbonate in obstetrics: guidelines for clinical use. Am J Obstet Gynecol 1973; 116 (1): 15-22
23. Schou M, Goldfield MD, Weinstein MR, et al. Lithium and pregnancy. I. Report from the register of lithium babies. BMJ 1973; 2: 135-6
24. Weinstein MR, Goldfield MD. Cardiovascular malformations with lithium use during pregnancy. Am J Psychiatry 1975; 132: 529-31
25. Nora JJ, Nora AH, Toews WH. Lithium, Ebstein's anomaly, and other congenital heart defects. Lancet 1974 Sep 7; 1: 594-5
26. Schou M. Lithium treatment during pregnancy, delivery, and lactation: an update. J Clin Psychiatry 1990; 51 (10): 410-3
27. Weinstein MR. Lithium treatment of women during pregnancy and the post-delivery period. In: Johnson FN, editor. Handbook of lithium therapy. Lancaster: MTP Press, 1980: 421-9
28. Correa-Villasenor A, Ferenez C, Neill CA, et al. The Baltimore-Washington Infant Study Group. Teratology 1994; 50 (2): 137-47
29. Kallen B, Tandberg A. Lithium and pregnancy: A cohort study on manic-depressive women. Acta Psychiatr Scand 1983; 68: 134-9
30. Jacobson SJ, Jones K, Johnson K, et al. Prospective multicentre study of pregnancy outcome after lithium exposure during first trimester. Lancet 1992; 339: 530-3
31. Zalzstein B, Koren G, Einarson T, et al. A case-control study on the association between first trimester exposure to lithium and Ebstein's anomaly. Am J Cardiol 1990; 65: 817-8
32. Edmonds LD, Oakley GP. Ebstein's anomaly and maternal lithium exposure during pregnancy. Teratology 1990; 41: 551-2
33. Kallen B. Comments on teratogen update: lithium. Teratology 1988; 38: 597
34. Czeizel A, Racz J. Evaluation of drug intake during pregnancy in the Hungarian case-control surveillance of congenital anomalies. Teratology 1990; 42: 505-12
35. Moore JA. An assessment of lithium using the IEHR evaluative process for assessing human development and reproductive toxicity of agents. Reprod Toxicol 1995; 9: 175-210
36. Cohen LS, Friedman JM, Jefferson JW, et al. A re-evaluation of risk of in utero exposure to lithium. JAMA 1994; 271 (2): 146-50
37. Jefferson JW, Greist JH, Ackerman DL, et al. Lithium encyclopedia for clinical practice. 2nd ed. Washington, DC: American Psychiatric Press, Inc., 1987
38. Woody JN, London WL, Wilbanks GDJ. Lithium toxicity in a newborn. Pediatrics 1971; 47 (1 Pt 1): 94-6
39. Wilbanks GD, Bressler B, Peete JCH, et al. Toxic effects of lithium carbonate in a mother and newborn infant. JAMA 1970; 213 (5): 865-7
40. Mackay AVP, Loose R, Glen AIM. Labour on lithium [letter]. BMJ 1976; 10: 878
41. Mizrahi EM, Hobbs JF, Goldsmith DI. Nephrogenic diabetes insipidus in transplacental lithium intoxication. J Pediatr 1979; 94 (3): 493-5
42. Krause S, Ebbesen F, Lange AP. Polyhydramnios with maternal lithium treatment. Obstet Gynecol 1990; 75: 504-6
43. Nars PW, Girard J. Clinical memorandum. Lithium carbonate intake during pregnancy leading to large goiter in a premature infant. Am J Dis Child 1977; 131: 924-5
44. Arnon RG, Marin-Garcia J, Peeden JN. Tricuspid valve regurgitation and lithium carbonate toxicity in a newborn infant. Am J Dis Child 1981; 135: 941-3
45. Filtenborg JA. Persistent pulmonary hypertension after lithium intoxication in the newborn. Eur J Pediatr 1982; 138: 321-3
46. Morrell P, Sutherland GR, Buamah PK, et al. Lithium toxicity in a neonate. Arch Dis Child 1983; 58: 539-41
47. Stevens D, Burman D, Midwinter A. Transplacental lithium poisoning. Lancet 1974 Sep 7; 1: 595
48. Troyer WA, Pereira GR, Lannon RA, et al. Association of maternal lithium exposure and premature delivery. J Perinatol 1993; XIII (2): 123-7
49. Allan ID, Desai G, Tynan MJ. Prenatal echocardiographic screening for Ebstein's anomaly for mothers on lithium therapy. Lancet 1982; II: 875-6
50. Schou M, Amdisen A. Lithium and pregnancy. III. Lithium ingestion by children breast-fed by women on lithium treatment. BMJ 1973; 21: 138
51. Buist A, Norman TR, Dennerstein L. Breastfeeding and the use of psychotropic medication: a review. J Affect Disord 1990; 19: 197-206
52. Tunnessen WW, Hertz CG. Toxic effects of lithium in newborn infants: a commentary. J Pediatr 1972; 81: 804-7
53. Schou M. What happened later to the lithium babies? A follow-up study of children born without malformations. Acta Psychiatr Scand 1976; 54: 193-7
54. Faedda GL, Tondo L, Baldessarini RJ, et al. Outcome after rapid vs gradual discontinuation of lithium treatment in bipolar disorders. Arch Gen Psychiatry 1993; 50: 448-54
55. Altshuler LL, Cohen L, Szuba MP, et al. Pharmacologic management of psychiatric illness during pregnancy: dilemmas and guidelines. Am J Psychiatry 1996; 153: 592-606
56. Kumur R, Isaacs S, Meltzer E. Recurrent post-partum psychosis. A model for prospective clinical investigation. Br J Psychiatry 1983; 142: 618-20
57. Stewart DE. Prophylactic lithium in postpartum affective psychosis. J Nerv Ment Dis 1988; 176 (8): 485-9
58. Schou M, Amdisen A, Steenstrup OR. Lithium and pregnancy. II. Hazards to women given lithium during pregnancy and delivery. BMJ 1973; 2: 137-8
59. Lier L, Kastrup M, Rafaelsen OJ. Psychiatric illness in relation to pregnancy and childbirth. II. Diagnostic profiles, psychosocial and perinatal aspects. Nord Psykiatr Tidsskr 1989; 43: 535-42