Tachykinin receptors are present on human monocytes and play a role in rheumatoid arthritis

Journal of Chemotherapy

Volumn 10, Issue 2, 1998, Pages 150-152

  Brunelleschi, S ^a   Colangelo, D ^a   Bordin, G ^b   Viano, I ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b MAGGIORE DELLA CARITÀ HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROKININ A; NEUROKININ A [4-10][8 BETA ALANINE]; NEUROKININ B; SENKTIDE; SUBSTANCE P; SUBSTANCE P DERIVATIVE; SUPEROXIDE; TACHYKININ RECEPTOR; TACHYKININ RECEPTOR AGONIST;

ADULT; AGED; CELL ISOLATION; CLINICAL ARTICLE; CLINICAL TRIAL; CONFERENCE PAPER; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG RECEPTOR BINDING; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; MONOCYTE; RHEUMATOID ARTHRITIS;

EID: 0031920751     PISSN: 1120009X     EISSN: None     Source Type: Journal    
DOI: 10.1179/joc.1998.10.2.150     Document Type: Conference Paper

References (10)

1. Mousli M, Bronner C, Bueb JL, Tschirhart E, Gies JP, Landry Y. Activation of rat peritoneal mast cells by substance P and mastoparan. J Pharmac Exp Ther 1989: 250: 329-335.
2. Payan DG, Brewster DR, Goetzl EJ. Specific stimulation of human T lymphocytes by substance P. J Immunol 1983; 131: 1613-5.
3. Brunelleschi S, Tarli S, Giotti A, Fantozzi R. Priming effects of mammalian tachykinins on human neutrophils. Life Sci 1991; 48: PL1-5.
4. 1 receptors. Br J Pharmacol 1990; 100: 417-20.
5. Brunelleschi S, Guidotto S, Viano I et al. Tachykinin activation of human alveolar macrophages in tobacco smoke and sarcoidosis: a phenotypical and functional study. Neuropeptides 1996; 30: 456-64.
6. Lotz M, Vaughan JH, Carson DA. Effects of neuropeptides on production of inflammatory cytokines by human monocytes. Science 1988; 241: 1218-21.
7. 1 protein, calcium, phospholipase D, MAP kinase and IL-6 production. J Immunol 1994; 153: 3691-99.
8. Levine JD, Clark R, Devor M, Helms C, Moskowitz MA, Bausbaum AI. Intraneural substance P contributes to the severity of experimental arthritis. Science 1984; 226: 547-9.
9. Lotz M, Carson DA, Vaughan JH. Substance P activation of rheumatoid synoviocytes: neural pathway in the pathogenesis of arthritis. Science 1987; 235: 893-5.
10. Devillier P, Weill BJ, Menkes CJ, Pradelles P, Renoux M. Elevated levels of tachykinin-like activity in joint fluid from patients with rheumatic inflammatory diseases. N Engl J Med 1986; 314: 1323.