Acute effects of hormone replacement with tibolone on myocardial ischaemia in women with angina

International Journal of Clinical Practice

Volumn 52, Issue 3, 1998, Pages 155-157

  Lloyd, G W L ^a,b   Patel, N R ^a   McGing, E A ^a   Cooper, A F ^a   Kamalvand, K ^a   Jackson, G ^a  

^a ST THOMAS HOSPITAL   (United Kingdom)

^b GUY'S AND ST THOMAS' NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANABOLIC AGENT; TIBOLONE;

ADULT; ANGINA PECTORIS; ARTICLE; CLINICAL ARTICLE; CORONARY ARTERY DISEASE; FEMALE; HEART MUSCLE ISCHEMIA; HEART RATE; HORMONE SUBSTITUTION; HUMAN; ORAL DRUG ADMINISTRATION; POSTMENOPAUSE; PRIORITY JOURNAL; ST SEGMENT DEPRESSION; SYSTOLIC BLOOD PRESSURE; TREADMILL EXERCISE;

ANABOLIC AGENTS; ANGINA PECTORIS; ELECTROCARDIOGRAPHY; ESTROGEN REPLACEMENT THERAPY; EXERCISE; FEMALE; HUMANS; MIDDLE AGED; MYOCARDIAL ISCHEMIA; NORPREGNENES; TIME FACTORS;

EID: 0031920731     PISSN: 13685031     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Stampfer MJ, Colditz GA, Willett WC et al. Post menopausal estrogen therapy and cardiovascular disease: ten year follow up from the nurses health study. N Engl J Med 1991; 325: 756-762.
2. Grodstein F, Stampfer MJ, Manson JE et al. Post menopausal estrogen and progestin use and the risk of cardiovascular disease. N Engl J Med 1996; 335(7): 435-461.
3. Sullivan JM, Zwaag RV, Lemp GF et al. Postmenopausal estrogen use and coronary atherosclerosis. Ann Intern Med 1988; 108: 358-363.
4. Rosano GM, Sarrel PM, Poole-Wilson PA, Collins P. Beneficial effects of oestrogen on exercise-induced myocardial ischaemia in women with coronary artery disease. Lancet 1993; 342: 133-135.
5. Rosano GM, Sarrel PM, Chierchia SL et al. Medroxyprogesterone but not natural progesterone reverses the beneficial effect of estradiol 17-beta on exercise induced myocardial ischemia. Circulation 1996; 91: 1-18 (Abstract).
6. Beale C, Rosano GM, Collins P. Chronic estrogen therapy improves exercise time to myocardial ischemia in postmenopausal women with coronary artery disease. JACC 1997; 29: 198a (Abstract).
7. Ross LA, Alder EM. Tibolone and climacteric symptoms. Maturitas 1995; 21: 127-136.
8. Lindsay R, McKhart D, Krauss RM. Prospective double blind trial of synthetic steroid (Org OD 14) for preventing postmenopausal osteoporosis. BMJ 1980; 280: 1207-1209.
9. Hardiman P, Nihoyannopoulos P, Kicovic P, Ginsburg J. Cardiovascular effects of Org OD 14, a new steroidal therapy for climacteric symptoms. Maturitas 1991; 13: 235-242.
10. Walker I, Davidson JF, Richards A et al. The effect of the synthetic steroid ORG OD 14 on fibrinolysis and blood lipids in postmenopausal women. Thromb Haemost 1985; 53: 303-305.
11. Rymer J, Crook D, Sidhu M et al. Effects of tibolone on serum concentrations of lipoprotein (a) in postmenopausal women. Acta Endocrinol 1993; 128: 259-262.
12. Gilligan DM, Quyyumi AA, Cannon RO. Effects of physiological levels of estrogen on coronary vasomotor function in postmenopausal women. Circulation 1994; 89: 2545-2551.
13. Collins P, Rosano GM, Sarrel PM, et al. 17-β-estradiol attenuates acetylcholine-induced coronary arterial constriction in women but not men with coronary heart disease. Circulation 1995; 92: 24-28.
14. Collins P, Beale C, Rosano GM. Oestrogen as a calcium blocker. Eur Heart J 1996; 17: 27-31.
15. Jiang C, Sarrel PM, Lindsay D et al. Endothelium-independent relaxation of rabbit coronary artery by 17β-oestradiol in vitro. Br J Pharmacol 1991; 104: 1033-1037.
16. 2+ currents in A7r5 vascular smooth muscle cell line. Am J Physiol 1994; 266: C975-C980.
17. Schray-utz B, Zeiher AM, Busse R. Expression of constitutive NO synthetase in cultured endothelial cells is enhanced by 17β-estradiol. Circulation 1993; 88: 1-80 (Abstract).
18. Collins P, Shay J, Jiang C, Moss J. Nitric oxide accounts for dose dependent estrogen-mediated coronary relaxation following acute estrogen withdrawal. Circulation 1994; 90: 1964-1968.
19. Lehmann ED, Hopkins KD, Parker JR et al. Aortic distensibility in postmenopausal women receiving tibolone. Br J Radiol 1994; 67: 701-705.