Cellular mechanisms of cardiac mechano-electric feedback in a mathematical model

Canadian Journal of Cardiology

Volumn 14, Issue 1, 1998, Pages 111-119

  Kohl, Peter ^a   Day, Kathryn ^a   Noble, Denis ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Cardiac electrophysiology; Computer model; Mechano electric feedback

Indexed keywords

CALCIUM ION; ION CHANNEL; TROPONIN C;

ARTICLE; CALCIUM CELL LEVEL; COMPUTER SIMULATION; DIASTOLE; EXCITATION CONTRACTION COUPLING; HEART ELECTROPHYSIOLOGY; HEART MUSCLE POTENTIAL; MATHEMATICAL MODEL; MUSCLE ISOMETRIC CONTRACTION; SARCOLEMMA; SARCOMERE LENGTH; SARCOPLASMIC RETICULUM; SYSTOLE;

ANIMALS; CALCIUM CHANNELS; ELECTROPHYSIOLOGY; FEEDBACK; HEART CONDUCTION SYSTEM; HEART RATE; HUMANS; MATHEMATICS; MECHANORECEPTORS; MODELS, CARDIOVASCULAR; MODELS, THEORETICAL; MYOCARDIUM;

EID: 0031920081     PISSN: 0828282X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Kohi P. Mechano-electric feedback: impact on heart rhythm. Futura 1995;10:240-52.
2. Lab MJ. Contraction-excitation feedback in myocardium. Physiological basis and clinical relevance. Circ Res 1982;50:757-66.
3. Pennington JE, Taylor J, Lown B. Chest thump for reverting ventricular tachycardia. N Engl J Med 1970;283:1192-5.
4. Blinks JR. Positive chronotropic effect of increasing right aerial pressure in the isolated mammalian heart. Am J Physiol 1956;186:299-303.
5. Hansen DE, Borganelli M, Stacy GP Jr, Taylor LK. Dose-dependent inhibition of stretch-induced arrhythmias by gadolinium in isolated canine ventricles. Evidence for a unique mode of antiarrhythmic action. CircRes 1991;69:820-31.
6. White E, Le Guennec JY, Nigretto JM, Cannier F, Argibay JA, Gamier D. The effects of increasing cell length on auxotonic contractions; membrane potentials and intracellular calcium transients in single guinea-pig ventricular myocytes. Exp Physiol 1993:78:65-78.
7. Kodama I, Arai A, Toyama J. Mechanical regulation of pacemaking activity in the sinoatrial node: roles of stretch-sensitive channels and calcium dynamics. Heart Vessels 1995;9:212-3.
8. Noble D. OXSOFT HEART Program Manual v4.8. Oxford: Oxsoft Ltd, 1997.
9. Sachs F. Modeling mechanical-electrical transduction in the heart. In: Mow Van C, Guliac F, Tran-son-Tray R, Hochmuth R, eds. Cell Mechanics and Cellular Engineering. New York: Springer Verlag, 1994:308-28.
10. Kohl P, Varghese A, Dekanski J, Noble D, Winslow RL. Computational study of the impact of cardiac mechanosensitive fibroblasts on heart rhythm. Exp Clin Cardiol 1996;l:80-6.
11. Noble D. The development of mathematical models of the heart. Chaos Solitons Fractals 1995;5:321-33.
12. ks and length- and tension-dependent processes. Can J Cardiol 1998;14:123-134.
13. Franz MR, Cima R, Wang D, Profitt D, Kurz R. Electrophysiological effects of myocardial stretch and mechanical determinants of stretch-activated arrhythmias. Circulation 1992;86:968-78.
14. Craelius W, Chen V, el-Sherif N. Stretch activated ion channels in ventricular myocytes. Biosci Rep 1988;8:407-14.
15. Craelius W. Stretch-activation of rat cardiac myocytes. Exp Physiol 1993;78:411-23.
16. Ruknudin A, Sachs F, Bustamante JO. Stretch-activated ion channels in tissue-cultured chick heart. Am J Physiol 1993;264:H960-72.
17. 2+ loading of sarcoplasmic reticulum in rat ventricular myocyte. Cardiovasc Res 1992;26:865-70.
18. Zabel M, Coller B, Franz MR. Amplitude and polarity of stretch-induced systolic and diastolic voltage changes depend on the timing of stretch: a means to characterize stretch-activated channels in the intact heart. PACE 1993;16:886.
19. Fabiato A, Fabiato F. Dependence of the contractile activation of skinned cardiac cells on the sarcomere length. Nature 1975;256:54-6.
20. Hilgemann DW, Noble D. Excitation-contraction coupling and extracellular calcium transients in rabbit atrium: reconstruction of basic cellular mechanisms. Proc R Soc Lond B Biol Sei 1987;230:163-205.