Intravenous injection with antisense oligodeoxynucleotides against angiotensinogen decreases blood pressure in spontaneously hypertensive rats

Hypertension

Volumn 31, Issue 5, 1998, Pages 1166-1170

  Makino, Naoki ^a   Sugano, Masahiro ^a   Ohtsuka, Shoji ^a   Sawada, Shojiro ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

Angiotensin II; Angiotensinogen; Antisense elements; Blood pressure; Genetics; Rats, inbred SHR

Indexed keywords

ANGIOTENSIN; ANGIOTENSINOGEN; ANTISENSE OLIGODEOXYNUCLEOTIDE; ASIALOGLYCOPROTEIN; MESSENGER RNA; OLIGODEOXYNUCLEOTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; INTRAVENOUS DRUG ADMINISTRATION; LIVER; NONHUMAN; PRIORITY JOURNAL; RAT; SPONTANEOUSLY HYPERTENSIVE RAT;

EID: 0031920005     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.31.5.1166     Document Type: Article

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