Inhibitory effects of α-viniferin and resveratrol on the L-dopa oxidase activity of tyrosinase

Medical Science Research

Volumn 26, Issue 4, 1998, Pages 235-237

  Kang, Bo Seong ^a   Shin, Nam Ho ^b   Lee, Seung Ho ^a   Min, Kyung Rak ^a   Kim, Youngsoo ^a  

^a Chungbuk National University   (South Korea)

^b Yeungnam University   (South Korea)

Author keywords

viniferin; L dopa oxidase activity; Mixed type inhibitor; Resveratrol; Tyrosinase

Indexed keywords

ALPHA VINIFERIN; CATECHOL OXIDASE; ENZYME INHIBITOR; MELANIN; MONOPHENOL MONOOXYGENASE; RESVERATROL; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG POTENCY; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME KINETICS; HYPERPIGMENTATION; MELANOGENESIS; SKIN COLOR;

EID: 0031919448     PISSN: 02698951     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Hearing VJ, Tsukamoto K. Enzymatic control of pigmentation in mammals. FASEB J 1991; 5:2902-2909.
2. Iwata M, Corn T, Iwata S, Everett MA, Fuller BB. The relationship between tyrosinase activity and skin color in human foreskins. / Invest Dermatol 1990; 95:9-15.
3. lozumi K, Hoganson GE, Pennella R, Everett MA, Fuller BB. Role of tyrosinase as the determinant of pigmentation in cultured human melanocytes. J Invest Dermatol 1993; 100:806-811.
4. Lee S-H, Shin H-H, Rang S-H, Park JS, Chung SR, Min KR. et al. Alpha-viniferin : a prostaglandin H2 synthase inhibitor from root of Carat humilis. Planta Med (in press).
5. Matsuda H, Nakamura S, Kubo M. Studies of cuticle drugs from natural sources. II. Inhibitory effects of Prunus plants or melanin biosynthesis. Biol Pharm Bull 1994; 17:1417-1420.
6. Kitanaka S, Ikezawa T, Yasukawa K, Yaraanouchi S, Takido M, Sung KH, et al. (+)-a-Viniferin, an anti-inflammatory compound from Caragana chamlagu Root. Chem Pharm Bull 1990; 28:432-435.
7. Kulanthaivel P, Janzen WP, Ballas LM, Jiang JB, Hu C-Q, Darges JW et al. Naturally occurring protein kinase C inhibitors; II Isolation of oligomeric stilbenes from Caragana sinica. Planta Med 1995; 61:41-44.
8. Kurihara H, Kawabata J, Ichikawa S, Mishima M, Mizutani J. Oligostilbenes from Carex kobomugi. Phytochem 1991; 30:649-653.
9. Jang M, Cai L, Udeani GO, Slowing KV, Thomas CF, Beecher CWW et al. Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science 1997; 275:218-220.
10. Shin NH, Ryu SY, Lee H, Min KR, Kim Y. Inhibitory effects of hydroxystilbenes on cyclooxygenase from sheep seminal vesicles. Planta Med 1997; 63:1-2.
11. Chen JS, Wei C, Rolla RS, Otwell WS, Balaban MO, Marshall MR. Inhibitory effect of kojic acid on some plant and crustacean polyphenol oxidases. J Agric Food Chem 1991; 39:1396-1401.
12. Shirota S, Miyazaki K, Aiyama R, Ichioka M, Yokokura T. Tyrosinase inhibitors from crude drugs. Biol Pharm Bull 1994; 17:266-269.
13. Canabes J, Garcia-Canovas F, Tudela J, Lozano JA, Garcia-Carmona F. L-Mimosine, a slow-binding inhibitor of mushroom tyrosinase. Phytochem 1987; 26:917-919.
14. Valrero E, Garcia-Moreno M, Varon R, Garcia-Carmona F. Time dependent inhibition of grape polyphenol oxidase by tropolone. J Agric Food Chem 1991; 39:1043-1046.
15. Schallreuter KU, Wood JW. A possible mechanism of action for azelaic acid in the human epidermis. Arch Dermatol Res 1990; 282:168-171.