Effect of streptolysin-O on rat hepatic acetyl coenzyme-a: Arylamine N- acetyltransferase and cytochrome P-450 2b1/2 activities ex vivo

Immunopharmacology and Immunotoxicology

Volumn 20, Issue 1, 1998, Pages 159-171

  Drobitch, Robert K ^a   Divakaruni, Prisanna ^a   Svensson, Craig K ^a  

^a WAYNE STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBENZOIC ACID; ARYLAMINE ACETYLTRANSFERASE; CYTOCHROME P450; DRUG METABOLIZING ENZYME; DRUG VEHICLE; EXOTOXIN; IMMUNOSTIMULATING AGENT; PROCAINAMIDE; STREPTOLYSIN O; SULFADIMIDINE; TOLBUTAMIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG ACETYLATION; DRUG EFFECT; DRUG HYDROXYLATION; ENZYME ACTIVITY; HEMOLYSIS; IMMUNOSTIMULATION; INTRAPERITONEAL DRUG ADMINISTRATION; LIVER CYTOSOL; LIVER MICROSOME; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STREPTOCOCCUS GROUP A; XENOBIOTIC METABOLISM;

ANIMALIA; STREPTOCOCCUS GROUP A; STREPTOCOCCUS SP. 'GROUP A';

EID: 0031918675     PISSN: 08923973     EISSN: None     Source Type: Journal    
DOI: 10.3109/08923979809034815     Document Type: Article

References (27)

1. Zidek, Z., Friebova, M., Janku, I. and Elis, J., Influence of sex and Freund's adjuvant on liver N-acetyltransferase activity and elimination of sulfadimidine in urine of rats, Biochem. Pharmacol., 26:69, 1977.
2. du Souich, P. A. and Courteau, H., Induction of acetylating capacity with Complete Freund's Adjuvant and hydrocortisone in the rabbit, Drug Metab. Dispos., 9:279, 1981.
3. Svensson, C. K. and Knowlton, P. W., Effect of the immunomodulator tilorone on the in vivo acetylation of procainamide in the rat, Pharm. Res. 6:477, 1989.
4. Drobitch, R. K., Tomilo, M. and Svensson, C. K., Immunomodulation and drug acetylation. Effect of the immunomodulator tilorone on hepatic, renal and blood N-acetyltransferase activity and on hepatic cytosolic acetyl CoA content, Biochem. Pharmacol., 43:1643, 1992.
5. Hadasova, E., Brysova, V. and Guida, O., Study of the acetylation activity in various species in vivo and its affection by streptolysin O, J. Pharmacol., 17:181, 1986.
6. Hadasova, E., Siegmund, W., Franke, G., Schneider, T., Beyrich, A., Bleyer, H. and Hubner, G., Drug oxidation and N-acetylation in rats pretreated with subtoxic doses of streptolysin O, Biochem. Pharmacol. 42:702, 1991.
7. Wannamaker, L. W., Streptococcal toxins, Rev. Infect. Dis., 5(Suppl 4):S723, 1983.
8. Renton, K. W. and Mannering, G J., Depression of hepatic cytochrome P-450-dependent monooxygenase systems with administration of interferon inducing agents, Biochem. Biophys. Res. Commun., 73:343, 1976.
9. Mannering, G. J., Renton, K. W., El Azhary, R. and Deloria, L. B., Effects of interferon-inducing agents on hepatic cytochrome P-450 drug metabolizing systems, Ann. N. Y. Acad. Sci., 350:314, 1980.
10. Mannering, G. J. and Deloria, L. B , The pharmacology and toxicology of the interferons: An overview, Ann. Rev. Pharmacol. Toxicol. 26:455, 1986.
11. Veronese, M. E., McManus, M. E., Laupattarakasem, P., Miners, J. O. and Birkett, D. J., Tolbutamide hydroxylation by human, rabbit and rat liver microsomes and by purified forms of cytochrome P-450, Drug Metab. Dispos., 18:356, 1990.
12. Rahman, S., Rebeyrotte, P., Halpern, B. and Besluau, D., Kinetics of streptolysin O reactivation by different thiols, Biochim. Biophys. Acta., 177: 658, 1969.
13. Gupta, R. K., Mehrotra, R. M. L. and Chaturvedi, U. C., Cardiotoxicity of Streptolysin 'O' in rats, Indian J. Med. Res., 61:1584, 1973.
14. Gupta, R. K., Antistreptolysin O response to streptolysin O in rats, Indian J. Pathol. Microbiol., 24:213, 1981.
15. Liu, L.-L., Knowlton, P. W. and Svensson, C. K., Effect of amiodarone on the disposition of procainamide in the rat, J. Pharm. Sci., 77:662, 1988.
16. 2-receptor antagonists on rat liver cytosolic Acetyl CoA:Arylamine N-acetyltransferase activity, Drug Metab. Dispos., 20:74, 1992.
17. Bradford, M. M., A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding, Anal. Biochem., 72: 248, 1976.
18. Lowry, O. H., Rosebrough, N. J., Farr, A. L. and Randall, R. J., Protein measurement with the Folin phenol reagent, J. Biol. Chem., 193:265, 1951.
19. Back, D.J., Sutcliffe, F. and Tjia, J. F., Tolbutamide as a model drug for the study of enzyme induction and enzyme inhibition in the rat, Br. J. Pharmacol., 81:557, 1984.
20. Guengerich, F. P., Dannan, G.A., Wright, S. T., Martin, V.V. and Kaminsky, L. S., Purification and characterization of liver microsomal cytochrome P450. Electrophoretic, spectral, catalytic, and immunochemical properties and inducibility of eight isozymes isolated from rats treated with phenobarbital or β-naphthoflavone, Biochemistry, 21:6019, 1982.
21. Armstrong, S. G. and Renton, K. W., Mechanism of hepatic cytochrome P450 modulation during Listeria monocytogenes infection in mice, Mol. Pharmacol., 43:542, 1993.
22. Renton, K. W. and Mannering, G.J., Depression of hepatic cytochrome P-450 dependent monooxygenase system by administered tilorone {2,7-bis[2- (diethylamino)ethoxy]fluoren- 9-one dihydrochloride}, Drug Metab. Dispos., 4:223, 1976.
23. Ansher, S. S., Puri, R. K., Thompson, W. C. and Habig, W. H., The effects of interleukin-2 and α-interferon administration on hepatic drug metabolism in mice, Cancer Res., 52:262, 1992.
24. Chen, Y. L., Florentin, I., Batt, A. M., Ferrari, L., Giroud, J. P. and Chauvelot-Moachon, L.,. Effect of interleukin-6 on cytochrome P450-dependent mixed-function oxidases in the rat, Biochem. Pharmacol. 44:137, 1992.
25. Hadasova, E., Siegmund, W., Walter, R., Scheuch, E. and Franke, G., Effects of streptolysin O, picibanil (OK 432) and Interferon α-2A on cytochrome P-450-dependent monooxygenases and arylamine N-acetyltransferase in rat liver. Immunopharmacol. Immunotoxicol., 17:283, 1995.
26. Walter, R., Siegmund, W. and Scheuch, E., Effects of interferon gamma and streptolysin O on hepatic procainamide N-acetyltransferase and various microsomal cytochrome P-450-dependent monooxygenases in rats, Immunopharmacol. Immunotoxicol., 18:571, 1996.
27. Walter, R., Hadasova, E., Scheuch, E. and Siegmund, W., Effects of streptolysin O, polyriboinosinic-polyribocytidylic acid and combinations with cyclophosphamide on the hepatic arylamine N-acetyltransferase and cytochrome P-450-dependent monooxygenases in rats, Pharmazie, 51: 498, 1996.