Nephrotoxic potential of antiinfective drugs as assessed by tissue-specific proteinuria of renal antigens

International Journal of Clinical Pharmacology and Therapeutics

Volumn 36, Issue 3, 1998, Pages 152-158

  Scherberich, J E ^a   Mondorf, W A ^b  

^a Abteilung fur Neurologie Stroke Unit Stad Krankenhaus Munchen Harlaching   (Germany)

^b NONE

Author keywords

Antibiotics; Human kidney; Image analysis; Nephrotoxicity; Proteinuria; Tissue proteinuria; Tubular antigens

Indexed keywords

AMIKACIN; AMINOGLYCOSIDE; ANTIBIOTIC AGENT; CEFALOTIN; CEFAZEDONE; CEFAZOLIN; CEFUROXIME; CEPHALOSPORIN DERIVATIVE; GENTAMICIN; MEMBRANE PROTEIN; NETILMICIN; SISOMICIN; TOBRAMYCIN;

ADOLESCENT; ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRUSH BORDER; CONTROLLED STUDY; DRUG POTENCY; HUMAN; HUMAN EXPERIMENT; IMAGE ANALYSIS; INTRAMUSCULAR DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; KIDNEY TUBULE CELL; MAJOR CLINICAL STUDY; MALE; NEPHROTOXICITY; NONHUMAN; NORMAL HUMAN; PROTEIN SYNTHESIS; PROTEIN URINE LEVEL; PROTEINURIA; RAT; TISSUE SPECIFICITY;

EID: 0031917986     PISSN: 09461965     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Chow AW, Azar RM 1994 Glycopeptides and nephrotoxicity. Intensive Care Med 4 (Suppl): 23-29
2. Gallose AM et al 1995 Aminoglycosides: single or multiple daily dosing? A meta-analysis on efficacy and safety. Eur J Clin Pharmacol 48: 39-43
3. Heinert G et al 1985 Use of quantitative enzyme-histochemical and morphometric image analysis in renal allografts in predicting the outcome after perfusion and cold storage. In: Lubec G, Campese V (eds) Advances in Noninvasive Nephrology. Libbey, London, pp 67-72
4. Kaloyanides GJ 1994 Antibiotic-related nephrotoxicity. Nephrol Dial Transplant 9 (Suppl 4): 130-134
5. Kasama R, Sorbello A 1996 Renal and electrolyte complications associated with antibiotic therapy. Am Fam Physician 53: 227-232
6. Melnick JZ, Baum M, Thompson JR 1994 Aminoglycoside-induced Fanconi syndrome. Am J Kidney Dis 23: 118-122
7. Mondorf WA et al 1984 Brush border enzymes and drug nephrotoxicity. In: Solez K, Whelton A (eds) Acute Renal Failure. Marcel Dekker, New York, pp 281-298
8. Mondorf AW, Scherberich JE, Hess H, Schoeppe W 1981 Differences in renal tolerance of aminoglycosides and their combinations with cephalosporins and cephalosporins with loop diuretics. Curr Chemother Immunother 12: 837-839
9. Pospishil YO, Antonovich TM 1996 Antibiotic-associated nephropathy. Pol J Pathol 47: 13-17
10. Scherberich JE 1989 Immunological and ultrastructural analysis of loss of tubular membrane-bound enzymes in patients with renal damage. Clin Chim Acta 185: 271-282
11. Scherberich JE et al 1989 Routine diagnosis with PhastSystem compared to conventional electrophoresis: automated sodium dodecyl sulfate-polyacrylamide gel electrophoresis, silver staining, and Western blotting of urinary proteins. Electrophoresis 10: 38-62
12. Scherberich JE, Wolf G, Schoeppe W 1993 Shedding and repair of renal cell membranes following drug induced nephrotoxicity in humans. Eur J Clin Pharmacol 44 (Suppl 1): 33-38
13. Scherberich JE, Wolf G 1994 Disintegration and recovery of kidney membrane proteins: consequence of acute and chronic renal failure. Kidney Int 46 (Suppl 47): 52-57
14. Schneider M et al 1996 Acute renal failure in cardiac surgical patients, potentiated by gentamicin and calcium. Anaesth Intensive Care 24: 647-650