Risedronate gastrointestinal absorption is independent of site and rate of administration

Pharmaceutical Research

Volumn 15, Issue 2, 1998, Pages 228-232

  Mitchell, David Y ^a   Eusebio, Rachelle A ^b   Dunlap, Lisa E ^b   Pallone, Karen A ^b   Nesbitt, John D ^b   Russell, Darrell A ^b   Clay, Marian E ^b   Bekker, Pirow J ^b  

^a PROCTER AND GAMBLE PHARMACEUTICALS   (United States)

^b NONE

Author keywords

Administration rate; Bisphosphonate; Gastrointestinal absorption; Gastrointestinal site; Pharmacokinetics; Risedronate

Indexed keywords

RISEDRONIC ACID;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG INFUSION; DRUG SCREENING; DRUG URINE LEVEL; GASTROINTESTINAL ABSORPTION; HEADACHE; HUMAN; HUMAN EXPERIMENT; INTRADUODENAL DRUG ADMINISTRATION; INTRAGASTRIC DRUG ADMINISTRATION; MALE; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; STOMACH INTUBATION;

AREA UNDER CURVE; CALCIUM CHANNEL BLOCKERS; DOSAGE FORMS; DUODENUM; ETIDRONIC ACID; HUMANS; ILEUM; INTESTINAL ABSORPTION; MALE; STOMACH;

EID: 0031917670     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1011910517200     Document Type: Article

References (22)

1. W. K. Sietsema, F. H. Ebetino, A. M. Salvagno and J. A. Bevan. Drugs Exp. Clin. Res. 15:389-396 (1989).
2. P. Bekker, A. Licata, S. Harris, H. Genant, P. Charles and C. Johnston. J. Bone Miner. Res. 11(Suppl 1):M658 (1996).
3. A. Chines, P. J. Bekker, P. Clarke and D. Hosking. J. Bone Miner. Res. 11(Suppl 1):M760 (1996).
4. C. Roux, P. Ravaud, M. Cohen-Solal, M. C. De Vernejoul, S. Guillemant, B. Cherruau, P. Delmas, M. Dougados and B. Amor. Bone. 15:41-49 (1994).
5. C. A. Reasner, M. D. Stone, D. J. Hosking, A. Ballah and G. Mundy. J. Clin. Endocrinol. Metab. 77:1067-1071 (1993).
6. D. Y. Mitchell, R. A. Eusebio, M. A. Heise, K. A. Pallone, M. E. Clay, D. A. Russell and C. W. Melson. J. Bone Miner. Res. 11:S347 (1996).
7. D. Y. Mitchell, R. A. Eusebio, L. E. Dunlap, D. A. Russell, M. E. Clay and P. J. Bekker. Pharm. Res. 13:S458 (1996).
8. D. Mitchell, R. Eusebio, K. Pallone, M. Clay, D. Russell and G. Thompson. Clin. Pharm. Ther. 61:155 (1997).
9. J. H. Lin. Bone. 18:75-85 (1996).
10. W. A. Ritschel. Methods Find. Exp. Clin. Pharmacol. 13:313-336 (1991).
11. R. P. Gural, V. S. Chung, R. P. Shewsbury and L. W. Dittert. J. Pharm. Pharmacol. 37:443-445 (1985).
12. J. H. Lin, I. W. Chen and F. A. deLuna. J. Pharm. Sci. 83:1741-1746 (1994).
13. B. J. Gertz, S. D. Holland, W. F. Kline, B. K. Matuszweski, A. Freeman, H. Quan, K. C. Lasseter, J. C. Mucklow and A. G. Porras. Clin. Pharmacol. Ther. 58:288-298 (1995).
14. X. Boulenc, C. Roques, H. Joyeux, Y. Berger and G. Fabre. Int. J. Pharmacol. 123:13-24 (1995).
15. X. Boulenc, T. Breul, J.-C. Gautier, P. Saudemon, H. Joyeux, C. Roques, Y. Berger and G. Fabre. Int. J. Pharmacol. 123:71-83 (1995).
16. T. T. Kararli. Biopharm. Drug Dispos. 16:351-380 (1995).
17. G. J. Yakatan, W. J. Poynor, R. L. Talbert, B. F. Floyd, C. L. Slough, R. S. Ampulski and J. J. Benedict. Clin. Pharmacol. Ther. 31:402-410 (1982).
18. J. Y. L. Reginster. Bone. 13:351-354 (1992).
19. B. J. Gertz, S. D. Holland, W. F. Kline, B. K. Matuszewski and A. G. Porras. Osteoporosis Int. Suppl 3:S13-S16 (1993).
20. L. Hyldstrup, G. Fleisch and S. A. Hauffe. Calcif. Tissue Int. 53:297-300 (1993).
21. J. E. Compston. Brit. Med. J. 309:711-715 (1994).
22. S. E. Papapoulos. In R. Marcus, D. Feldman and J. Kelsey (Eds), Osteoporosis, Academic Press, San Diego pp 1209-1234 (1996).