Cellular proliferation and UCP content in brown adipose tissue of cold- exposed aging Fischer 344 rats

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 274, Issue 1 43-1, 1998, Pages

  Florez Duquet, Maria ^a   Horwitz, Barbara A ^a   McDonald, Roger B ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Insulin like growth factor I; Nonshivering thermogenesis; Norepinephrine

Indexed keywords

NORADRENALIN; SOMATOMEDIN C; UNCOUPLING PROTEIN;

ADOLESCENT; AGED; AGING; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BROWN ADIPOSE TISSUE; CELL PROLIFERATION; COLD EXPOSURE; CONTROLLED STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; THERMOGENESIS;

EID: 0031916153     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.1998.274.1.r196     Document Type: Article

References (48)

1. Boss, O., S. Samec, A. Paoloni-Giacobino, C. Rossier, A. Dulloo, J. Seydoux, P. Muzzin, and J.-P. Giacobino. Uncoupling protein-e: a new member of the mitochondrial carrier family with tissue-specific expression. FEBS Lett. 408: 39-42, 1997.
2. 3 adrenoceptors. J. Biol. Chem. 267: 2006-2013, 1992.
3. Bukowiecki, L., A. J. Collet, N. Follea, G. Guay, and L. Jahjah. Brown adipose tissue hyperplasia: a fundamental mechanism of adaptation to cold and hyperphagia. Am. J. Physiol. 242 (Endocrinol. Metab. 5): E353-E359, 1982.
4. Bukowiecki, L. J., A. Geloen, and A. J. Collet. Proliferation and differentiation of brown adipocytes from interstitial cells during cold acclimation. Am. J. Physiol. 250 (Cell Physiol. 19): C880-C887, 1986.
5. Cameron, I. L., and R. E. Smith. Cytological responses of brown fat tissue in cold-exposed rats. J. Cell Biol. 23: 89-100, 1964.
6. Cristofalo, V. J., and R. J. Pignolo. Cell culture as a model. In: Handbook of Physiology. Aging. Bethesda, MD: Am. Physiol. Soc., 1995, sect. 11, chapt. 4, p. 53-82.
7. Daughaday, W. H., I. K. Mariz, and S. L. Blethen. Inhibition of access of bound somatomedin to membrane receptor and immunobinding sites. Acomparison of radioreceptor and radioimmunoassay of somatomedin in native and acid-ethanol extracted serum. J. Clin. Endocrinol. Metab. 51: 781-788, 1980.
8. Eiffert, K. C., J. S. Stern, B. A. Horwitz, L. M. Larkin, and R. B. McDonald. Effect of age and high sucrose diet on 2-deoxyglucose uptake in perfused hindlimb. J. Gerontol. B Bio. Med. Sci. 48: B206-B212, 1993.
9. Fleury, C., M. Meverova, S. Collins, S. Raimbault, O. Champigny, C. Levi-Meyrues, F. Bouillard, M. Seidin, R. S. Surwit, D. Ricquier, and C. Warden. Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia. Nat. Genet. 15: 269-272, 1997.
10. Gabaldon, A. M., M. L. Florez-Duquet, J. S. Hamilton, R. B. McDonald, and B. A. Horwitz. Effects of age and gender on brown fat and skeletal muscle metabolic responses to cold in F344 rats. Am. J. Physiol. 268 (Regulatory Integrative Comp. Physiol. 37): R931-R941, 1995.
11. Geloen, A., A. J. Collet, and L. J. Bukowiecki. Role of sympathetic innervation in brown adipocyte proliferation. Am. J. Physiol. 263 (Regulatory Integrative Comp. Physiol. 32): R1176-R1181, 1992.
12. Geloen, A., A. J. Collet, G. Guay, and L. J. Bukowiecki. β-Adrenergic stimulation of brown adipocyte proliferation. Am. J. Physiol. 254 (Cell Physiol. 23): C175-C182, 1988.
13. Girardier, L., and J. Seydoux. Neural control of brown adipose tissue. In: Brown Adipose Tissue, edited by P. Trayhurn and D. G. Nicholls. London: Arnold, 1986, p. 122-151.
14. Harada, E., Y. Habara, and T. Kanno. Cold acclimation in insulin secretion of isolated perfused pancreas of the rat. Am. J. Physiol. 242 (Endocrinol. Metab. 5): E360-E367, 1982.
15. Himms-Hagen, J. Brown adipose tissue thermogenesis: interdisciplinary studies. FASEB J. 4: 2890-2898, 1990.
16. Horan, M. A., R. A. Little, N. J. Rothwell, and M. J. Stock. Changes in body composition, brown adipose tissue activity and thermogenic capacity in BN/BiRij rats undergoing senescence. Exp. Gerontol. 23: 455-461, 1988.
17. Horwitz, B. A., R. B. McDonald, and A. M. Gabaldon. Aging and gender effects on adrenergic-stimulated respiration of brown adipocytes from F344 rats. FASEB J. 10: A220, 1996.
18. Horwitz, B.A., R. B. McDonald, and J. S. Stern. Thermoregulation in older mammals: altered thermogenesis during cold exposure. In: Milestones in Environmental Physiology, edited by M. K Yousef. The Hague, The Netherlands: SPB Academic, 1989, p. 43-51.
19. Kawate, R., M. I. Talan, and B. T. Engel. Aged C57BL/6J mice respond to cold with increased sympathetic nervous activity to interscapular brown adipose tissue. J. Gerontol. B Bio. Med. Sci. 48: B180-B183, 1993.
20. Klaus, S., M. Ely, D. Encke, and G. Heldmaier. Functional assessment of white and brown adipocyte development and energy metabolism in cell culture. Dissociation of terminal differentiation and thermogenesis in brown adipocytes. J. Cell Sci. 108: 3171-3180, 1995.
21. Kozak, U. C., and L. P. Kozac. Norepinephrine-dependent selection of brown adipocyte cell lines. Endocrinology 134: 906-913, 1994.
22. Larkin, L. M., B. Horwitz, K. Eiffert, and R. B. McDonald. Adrenergic stimulated skeletal muscle glycogenolysis in perfused hindlimbs of young and old male Fischer 344 rats. Am. J. Physiol. 266 (Regulatory Integrative Comp. Physiol. 35): R749-R755, 1994.
23. Larkin, L. M., B. A. Horwitz, and R. B. McDonald. Effect of cold on serum substrate and glycogen concentration in young and old Fischer 344 rats. Exp. Gerontol. 27: 179-190, 1992.
24. Lean, M. E. J., W. J. Branch, W. P. T. James, G. Jennings, and M. Ashwell. Measurement of rat brown-adipose-tissue mitochondrial uncoupling protein by radioimmunoassay: increased concentration after cold acclimation. Biosci. Rep. 3: 61-71, 1983.
25. Lowry, O. H., N. J. Rosenbrough, A. L. Farr, and R. J. Randal. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193: 265-275, 1951.
26. Marko, O., M. A. Cascieri, N. Ayad, C. D. Strader, and M. R. Candelore. Isolation of a preadipocyte line from rat bone marrow and differentiation to adipocytes. Endocrinology 136: 4582-4588, 1995.
27. Martin, G., C. Sprague, and C. Epstein. Replicative life-span of cultivated human cells: effects of donor's age, tissue, and genotype. Lab. Invest. 23: 86-91, 1970.
28. Martin, G. M., C. E. Ogburn, and C. A. Sprague. Effects of age on cell division capacity. In: Aging: a Challenge to Science and Society: Biology, edited by D. Danon, N. W. Shock, and M. Marois. Oxford, UK: Oxford Univ. Press, 1981, p. 124-135.
29. McDonald, R. B. Effect of age and diet on glucose tolerance in Sprague-Dawley rats. J. Nutr. 120: 598-601, 1990.
30. McDonald, R. B., C. Day, K. Carlson, J. S. Stern, and B. A. Horwitz. Effect of age and gender on thermoregulation. Am. J. Physiol. 257 (Regulatory Integrative Comp. Physiol. 26): R700-R704, 1989.
31. McDonald, R. B., M. Florez-Duquet, C. Murtagh-Mark, and B. A. Horwitz. Relationship between cold-induced thermoregulation and spontaneous rapid body weight loss of aging F344 rats. Am. J. Physiol. 271 (Regulatory Integrative Comp. Physiol. 40): R1115-R1122, 1996.
32. McDonald, R. B., J. S. Hamilton, and B. A. Horwitz. Influence of age and gender on brown adipose tissue norepinephrine turnover. Proc. Soc. Exp. Biol. Med. 204: 117-121, 1993.
33. McDonald, R. B., J. S. Hamilton, J. S. Stern, and B. A. Horwitz. Regional blood flow of exercise-trained younger and older cold-exposed rats. Am. J. Physiol. 256 (Regulatory Integrative Comp. Physiol. 25): R1069-R1075, 1989.
34. McDonald, R. B., B. A. Horwitz, J. S. Hamilton, and J. S. Stern. Cold- and norepinephrine-induced thermogenesis in younger and older Fischer 344 rats. Am. J. Physiol. 254 (Regulatory Integrative Comp. Physiol. 23): R457-R462, 1988.
35. McDonald, R. B., C. M. Murtagh, and B. A. Horwitz. Age and gender effects of glucose utilization in skeletal muscle and brown adipose tissue of cold-exposed rats. Proc. Soc. Exp. Biol. Med. 207: 102-109, 1994.
36. Mooradian, A. D., and P. J. Scarpace. β-Adrenergic receptor activity of cerebral microvessels is reduced in aged rats. Neurochem. Res. 16: 447-451, 1991.
37. Nedergaard, J., G. Bronnikov, V. Golozoubova, S. Rehnmark, T. Bengtsson, H. Thonberg, A. Jacobsson, and B. Cannon. Brown adipocyte differentiation: an innate switch in adrenergic receptor endowment and in adrenergic response. In: Obesity in Europe 1993, edited by H. Ditschuneit, F. A. Gries, H. Hauner, V. Schusdziarra, and J. G. Wechsler. London: Libbey, 1994, p. 73-80.
38. Park, I. R. A., and J. Himms-Hagen. Neural influences on trophic changes in brown adipose tissue during cold acclimation. Am. J. Physiol. 255 (Regulatory Integrative Comp. Physiol. 24): R874-R881, 1988.
39. Rheinwald, J. G., and H. Green. Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinizing colonies from single cells. Cell 6: 331-344, 1975.
40. Scarpace, P. J., D. T. Lowenthal, and N. Tumer. Influence of exercise and age on myocardial β-adrenergic receptor properties. Exp. Gerontol. 27: 169-177, 1992.
41. Scarpace, P. J., M. Matheny, and S. E. Borst. Thermogenesis and mitochondrial GDP binding with age in response to the novel agonist CGP-12177A. Am. J. Physiol. 262 (Endocrinol. Metab. 25): E185-E190, 1992.
42. Scarpace, P. J., A. D. Mooradian, and J. E. Morley. Age-associated decrease in beta-adrenergic receptors and adenylate cyclase activity in rat brown adipose tissue. J. Gerontol. B Bio. Med. Sci. 43: B65-B70, 1988.
43. Shu, Y., and P. J. Scarpace. Forskolin binding sites and G-protein immunoreactivity in rat hearts during aging. J. Cardiovasc. Pharmacol. 23: 188-193, 1994.
44. Sugawa, M., and T. May. Age-related alteration in signal transduction: involvement of the cAMP cascade. Brain Res. 618: 57-62, 1993.
45. Vallerand, A. L., J. Lupien, and L. J. Bukowiecki. Cold exposure reverses the diabetogenic effects of high-fat feeding. Diabetes 35: 329-334, 1986.
46. Wilson, P. D., and M. A. Dillingham. Age-associated decrease in vasopressin-induced renal water transport: a role for adenylate cyclase and G protein malfunction. Gerontology 38: 315-321, 1992.
47. Yamashita, H., S. Oh-ishi, T. Kizaki, J. Nagasawa, D. Saitoh, Y. Ohira, and H. Ohno. Insulin stimulates the expression of basic fibroblast growth factor in rat brown adipocyte primary culture. Eur. J. Cell Biol. 68: 8-13, 1995.
48. Yamashita, H., M. Yamamoto, T. Ookawara, Y. Sato, N. Ueno, and H. Ohno. Discordance between thermogenic activity and expression of uncoupling protein in brown adipose tissue of old rats. J. Gerontol. B Bio. Med. Sci. 49: B54-B59, 1994.