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Volumn 76, Issue 1, 1998, Pages 31-37

Inhibition of delayed rectifier K+ current by dofetilide and E-4031 differentially affects electrical cardiac responses to vagus stimulation in anesthetized dogs

Author keywords

Disopyramide; Dofetilide; E 4031; Parasympathetic nervous system; Refractory period

Indexed keywords

1 [2 (6 METHYL 2 PYRIDYL)ETHYL] 4 (4 METHYLSULFONYLAMINOBENZOYL)PIPERIDINE; DISOPYRAMIDE; DOFETILIDE;

EID: 0031915716     PISSN: 00215198     EISSN: None     Source Type: Journal    
DOI: 10.1254/jjp.76.31     Document Type: Article
Times cited : (6)

References (30)
  • 1
    • 0025676658 scopus 로고
    • Channel specificity in antiarrhythmic drug action: Mechanism of potassium channel block and its role in suppressing and aggravating cardiac arrhythmias
    • Colatsky TJ, Follmer CH and Starmer CF: Channel specificity in antiarrhythmic drug action: Mechanism of potassium channel block and its role in suppressing and aggravating cardiac arrhythmias. Circulation 82, 2235-2242 (1990)
    • (1990) Circulation , vol.82 , pp. 2235-2242
    • Colatsky, T.J.1    Follmer, C.H.2    Starmer, C.F.3
  • 4
    • 2642619678 scopus 로고
    • Effects of a novel class 3 antiarrhythmic agent, E-4031, on ventricular arrhythmias
    • Sawada K, Nomoto K and Hiraoka M: Effects of a novel class 3 antiarrhythmic agent, E-4031, on ventricular arrhythmias. Jpn Circ J 52, 919 (1988)
    • (1988) Jpn Circ J , vol.52 , pp. 919
    • Sawada, K.1    Nomoto, K.2    Hiraoka, M.3
  • 5
    • 0026021522 scopus 로고
    • Effects of the new class III antiarrhythmic drug E-4031 on myocardial contractility and electrophysiological parameters
    • Wettwer E, Scholtysik G, Schaad A, Himmel H and Ravens U: Effects of the new class III antiarrhythmic drug E-4031 on myocardial contractility and electrophysiological parameters. J Cardiovasc Pharmacol 17, 480-487 (1991)
    • (1991) J Cardiovasc Pharmacol , vol.17 , pp. 480-487
    • Wettwer, E.1    Scholtysik, G.2    Schaad, A.3    Himmel, H.4    Ravens, U.5
  • 6
    • 0025351245 scopus 로고
    • + current: Differential sensitivity to block by class III antiarrhythmic agents
    • + current: Differential sensitivity to block by class III antiarrhythmic agents. J Gen Physiol 96, 195-215 (1990)
    • (1990) J Gen Physiol , vol.96 , pp. 195-215
    • Sanguinetti, M.C.1    Jurkiewicz, N.K.2
  • 7
    • 0025978588 scopus 로고
    • + current is composed of two currents in guinea pig atrial cells
    • + current is composed of two currents in guinea pig atrial cells. Am J Physiol 260, H393-H399 (1991)
    • (1991) Am J Physiol , vol.260
    • Sanguinetti, M.C.1    Jurkiewicz, N.K.2
  • 10
    • 0030087726 scopus 로고    scopus 로고
    • Selective inhibition by a class III antiarrhythmic agent, E-4031, of the negative chronotropic response to parasympathetic stimulation in anesthetized dogs
    • Imamura H, Furukawa Y, Nakano H, Kasama M, Hoyano Y and Chiba S: Selective inhibition by a class III antiarrhythmic agent, E-4031, of the negative chronotropic response to parasympathetic stimulation in anesthetized dogs. J Pharmacol Exp Ther 276, 467-472 (1996)
    • (1996) J Pharmacol Exp Ther , vol.276 , pp. 467-472
    • Imamura, H.1    Furukawa, Y.2    Nakano, H.3    Kasama, M.4    Hoyano, Y.5    Chiba, S.6
  • 11
    • 0001312699 scopus 로고
    • Nonuniform distribution of vagal effects on the atrial refractory period
    • Alessi R, Nusynowitz M, Abildskov JA and Moe GK: Nonuniform distribution of vagal effects on the atrial refractory period. Am J Physiol 194, 406-410 (1958)
    • (1958) Am J Physiol , vol.194 , pp. 406-410
    • Alessi, R.1    Nusynowitz, M.2    Abildskov, J.A.3    Moe, G.K.4
  • 12
    • 0002424968 scopus 로고
    • Cardiac vagal activity, myocardial ischemia and sudden death
    • Edited by Zipes DP and Jalife J, WB Saunders Co, Philadelphia
    • De Ferrari GM, Vanoli E and Schwartz PJ: Cardiac vagal activity, myocardial ischemia and sudden death. In Cardiac Electrophysiology: From Cell to Bedside, Edited by Zipes DP and Jalife J, pp 422-434, WB Saunders Co, Philadelphia (1995)
    • (1995) Cardiac Electrophysiology: From Cell to Bedside , pp. 422-434
    • De Ferrari, G.M.1    Vanoli, E.2    Schwartz, P.J.3
  • 13
    • 0002334850 scopus 로고
    • Pharmacology of a new anti-arrhythmic agent, γ-diisopropylamino-α-phenyl-α-(2-pyridyl)-butyramide (SC-7031)
    • Mokler CM and Van Arman CG: Pharmacology of a new anti-arrhythmic agent, γ-diisopropylamino-α-phenyl-α-(2-pyridyl)-butyramide (SC-7031). J Pharmacol Exp Ther 136, 114-124 (1962)
    • (1962) J Pharmacol Exp Ther , vol.136 , pp. 114-124
    • Mokler, C.M.1    Van Arman, C.G.2
  • 14
    • 0017700919 scopus 로고
    • Dual effect of disopyramide on atrial and atrioventricular conduction and refractory periods
    • Birkhead JS and Vaughan Williams EM: Dual effect of disopyramide on atrial and atrioventricular conduction and refractory periods. Br Heart J 39, 657-660 (1977)
    • (1977) Br Heart J , vol.39 , pp. 657-660
    • Birkhead, J.S.1    Vaughan Williams, E.M.2
  • 15
    • 0019137402 scopus 로고
    • Anti-cholinergic effects of disopyramide and quinidine on guinea pig myocardium: Mediation by direct muscarinic receptor blockade
    • Mirro MJ, Manalan AS, Bailey JC and Watanabe AM: Anti-cholinergic effects of disopyramide and quinidine on guinea pig myocardium: Mediation by direct muscarinic receptor blockade. Circ Res 47, 855-865 (1980)
    • (1980) Circ Res , vol.47 , pp. 855-865
    • Mirro, M.J.1    Manalan, A.S.2    Bailey, J.C.3    Watanabe, A.M.4
  • 16
    • 0013950768 scopus 로고
    • Functional distribution of the peripheral cardiac sympathetic pathways
    • Levy MN, Ng ML and Zieske H: Functional distribution of the peripheral cardiac sympathetic pathways. Circ Res 19, 650-661 (1966)
    • (1966) Circ Res , vol.19 , pp. 650-661
    • Levy, M.N.1    Ng, M.L.2    Zieske, H.3
  • 18
    • 0025762512 scopus 로고
    • Negative chronotropic effect of a novel class III antiarrhythmic drug, UK-68,798, devoid of β-blocking action on isolated guinea pig atria
    • Yang T, Tande PM and Refsum H: Negative chronotropic effect of a novel class III antiarrhythmic drug, UK-68,798, devoid of β-blocking action on isolated guinea pig atria. Br J Pharmacol 103, 1417-1420 (1991)
    • (1991) Br J Pharmacol , vol.103 , pp. 1417-1420
    • Yang, T.1    Tande, P.M.2    Refsum, H.3
  • 19
    • 0025994279 scopus 로고
    • Cardiac electrophysiologic and inotropic actions of new and potent methanesulfonanilide class III antiarrhythmic agents in anesthetized dogs
    • Wallace AA, Stupienski RF, Brookes LM, Selnick HG, Claremon DA and Lynch JJ Jr: Cardiac electrophysiologic and inotropic actions of new and potent methanesulfonanilide class III antiarrhythmic agents in anesthetized dogs. J Cardiovasc Pharmacol 18, 687-695 (1991)
    • (1991) J Cardiovasc Pharmacol , vol.18 , pp. 687-695
    • Wallace, A.A.1    Stupienski, R.F.2    Brookes, L.M.3    Selnick, H.G.4    Claremon, D.A.5    Lynch Jr., J.J.6
  • 20
    • 0026620880 scopus 로고
    • Effects of WAY-123,398, a new class III antiarrhythmic agent, on cardiac refractoriness and ventricular fibrillation threshold in anesthetized dogs: A comparison with UK-68,798, E-4031, and dl-sotalol
    • Spinelli W, Parsons RW and Colatsky TJ: Effects of WAY-123,398, a new class III antiarrhythmic agent, on cardiac refractoriness and ventricular fibrillation threshold in anesthetized dogs: a comparison with UK-68,798, E-4031, and dl-sotalol. J Cardiovasc Pharmacol 20, 913-922 (1992)
    • (1992) J Cardiovasc Pharmacol , vol.20 , pp. 913-922
    • Spinelli, W.1    Parsons, R.W.2    Colatsky, T.J.3
  • 21
    • 0028935894 scopus 로고
    • Effects of delayed rectifier current blockade by E-4031 on impulse generation in single sinoatrial nodal myocytes of the rabbit.
    • Verheijck EE, Ginneken ACG, Bourier J and Bouman LN: Effects of delayed rectifier current blockade by E-4031 on impulse generation in single sinoatrial nodal myocytes of the rabbit. Circ Res 76, 607-615 (1995)
    • (1995) Circ Res , vol.76 , pp. 607-615
    • Verheijck, E.E.1    Ginneken, A.C.G.2    Bourier, J.3    Bouman, L.N.4
  • 22
    • 0018830078 scopus 로고
    • Electrophysiological effects of disopyramide and quinidine on guinea pig atria and canine cardiac Purkinje fibers: Dependence on underlying cholinergic tone
    • Mirro MJ, Watanabe AM and Bailey JC: Electrophysiological effects of disopyramide and quinidine on guinea pig atria and canine cardiac Purkinje fibers: Dependence on underlying cholinergic tone. Circ Res 46, 660-668 (1980)
    • (1980) Circ Res , vol.46 , pp. 660-668
    • Mirro, M.J.1    Watanabe, A.M.2    Bailey, J.C.3
  • 23
    • 0024593814 scopus 로고
    • Anti-cholinergic effects of quinidine, disopyramide, and procainamide in isolated atrial myocytes: Mediation by different molecular mechanisms
    • Nakajima T, Kurachi Y, Ito H, Takikawa R and Sugimoto T: Anti-cholinergic effects of quinidine, disopyramide, and procainamide in isolated atrial myocytes: Mediation by different molecular mechanisms. Circ Res 64, 297-303 (1989)
    • (1989) Circ Res , vol.64 , pp. 297-303
    • Nakajima, T.1    Kurachi, Y.2    Ito, H.3    Takikawa, R.4    Sugimoto, T.5
  • 25
    • 0029057635 scopus 로고
    • Anti-cholinergic effects of class III antiarrhythmic drugs in guinea pig atrial cells: Different molecular mechanisms
    • Mori K, Hara Y, Saito T, Masuda Y and Nakaya H: Anti-cholinergic effects of class III antiarrhythmic drugs in guinea pig atrial cells: different molecular mechanisms. Circulation 91, 2834-2843 (1995)
    • (1995) Circulation , vol.91 , pp. 2834-2843
    • Mori, K.1    Hara, Y.2    Saito, T.3    Masuda, Y.4    Nakaya, H.5
  • 26
    • 0026640423 scopus 로고
    • + current in cardiac myocytes by dofetilide
    • + current in cardiac myocytes by dofetilide. J Pharmacol Exp Ther 262, 809-817 (1992)
    • (1992) J Pharmacol Exp Ther , vol.262 , pp. 809-817
    • Carmeliet, E.1
  • 27
    • 0028085035 scopus 로고
    • Voltage dependence of cardiac delayed rectifier block by methanesulfonamide class III antiarrhythmic agents
    • Krafte DS and Volberg WA: Voltage dependence of cardiac delayed rectifier block by methanesulfonamide class III antiarrhythmic agents. J Cardiovasc Pharmacol 23, 37-41 (1994)
    • (1994) J Cardiovasc Pharmacol , vol.23 , pp. 37-41
    • Krafte, D.S.1    Volberg, W.A.2
  • 29
    • 0019521314 scopus 로고
    • Effect of autonomic blockade on ventricular refractoriness and atrioventricular conduction in man: Evidence supporting a direct cholinergic action on ventricular muscle refractoriness
    • Prytowsky EN, Jackman WM, Rinkenberger RL, Heger JJ and Zipes DP: Effect of autonomic blockade on ventricular refractoriness and atrioventricular conduction in man: evidence supporting a direct cholinergic action on ventricular muscle refractoriness. Circ Res 49, 511-518 (1981)
    • (1981) Circ Res , vol.49 , pp. 511-518
    • Prytowsky, E.N.1    Jackman, W.M.2    Rinkenberger, R.L.3    Heger, J.J.4    Zipes, D.P.5
  • 30
    • 0025164907 scopus 로고
    • Class III antiarrhythmic agents have a lot of potential but a long way to go: Reduced effectiveness and dangers of reverse use dependence
    • Hondeghem LM and Snyders DJ: Class III antiarrhythmic agents have a lot of potential but a long way to go: Reduced effectiveness and dangers of reverse use dependence. Circulation 81, 686-690 (1990)
    • (1990) Circulation , vol.81 , pp. 686-690
    • Hondeghem, L.M.1    Snyders, D.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.