Elevated biliary calmodulin during gallstone formation. The role of bile acids

Digestive Diseases and Sciences

Volumn 43, Issue 1, 1998, Pages 170-177

  Moser, A James ^b   Karam, Joseph A ^b   Giurgiu, Dan I ^b   Weber, Philip A ^b   Abedin, Zahidur R ^b   Roslyn, Joel J ^b   Abedin, Mohammad Z ^a  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b NONE

Author keywords

Bile acids; Calmodulin; Gallstones; Phospholipids; Prairie dog; Secretion

Indexed keywords

BILE ACID; CALCIUM ION; CALMODULIN; CHOLESTEROL; PHOSPHOLIPID; RECEPTOR PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE ACID SYNTHESIS; BILE LEVEL; CANNULATION; CHOLECYSTECTOMY; CHOLELITHIASIS; CHOLESTEROL INTAKE; COMMON BILE DUCT; CONTROLLED STUDY; DIET; GALLSTONE FORMATION; HYDROPHOBICITY; MALE; NONHUMAN; PHOSPHOLIPID SYNTHESIS; PRIORITY JOURNAL; RADIOIMMUNOASSAY;

ANIMALS; BILE; CALMODULIN; CHOLELITHIASIS; CHOLESTEROL; GALLBLADDER; LIVER; MALE; PHOSPHOLIPIDS; SCIURIDAE; TAUROCHOLIC ACID;

EID: 0031915331     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1018852810678     Document Type: Article

References (47)

1. Cheung WY: Calmodulin plays a pivotal role in cellular regulation. Science 207:19-27, 1980
2. Schulman H, Greengard P: Stimulation of brain membrane protein phosphorylation by calcium and an endogenous heat-stable protein. Nature 271:478-479, 1978
3. 2+-calmodulin regulates basal gallbladder absorption. Surgery 114:300-307, 1993
4. 2+-calmodulin-dependent phosphorylation and dephosphorylation of rat parotid secretion granules. Biochem Biophys Res Commun 215(1):75-81, 1995
5. 2+ ionophores. Biochemistry 30(35):8598-8604, 1991
6. Boyer JL, Soroka CJ: Vesicle targeting to the apical domain regulates bile excretory function in isolated rat hepatocyte couplets. Gastroenterology 109(5):1600-1611, 1995
7. Brenneman DE, Connor WE, Forker EL, DenBesten L: The formation of abnormal bile and cholesterol gallstones from dietary cholesterol in the prairie dog. J Clin Invest 51:1495-1503, 1972
8. Roslyn JJ, Conter RL, DenBesten L: Altered gallbladder concentration of biliary lipids during early cholesterol gallstone formation. Dig Dis Sci 32:609-614, 1987
9. Lee SP: Enhanced fluid transport across gallbladder mucosa in experimental cholelithiasis. Am J Physiol 3:E575-E578, 1978
10. La Morte WW, Schoetz DJ Jr, Birkett DH, Williams LF Jr: The role of the gallbladder in the pathogenesis of cholesterol gallstones. Gastroenterology 77:580-592, 1979
11. Conter RL, Roslyn JJ, Porter-Fink V, DenBesten L: Gallbladder absorption increases during early cholesterol gallstone formation. Am J Surg 151:184-191, 1986
12. Singhal AK, Cohen BI, Finver-Sadowsky J, McSherry CK, Mosbach EH: Role of hydrophilic bile acids and of sterols on cholelithiasis in the hamster. J Lipid Res 25:564-570, 1964
13. Abedin MZ, Giurgiu DIN, Karam JA, Abedin ZR, Roslyn JJ: Calmodulin activity is altered during gallstone formation. Gastroenterology 108:A1021, 1995 (abstract)
14. Swell L, Entenman C, Leong GF, Holloway RJ: Bile acids and lipid metabolism. IV. Influence of bile acids on biliary and liver organelle phospholipids and cholesterol. Am J Physiol 215:1390-1396, 1968
15. Downling RH, Mack E, Small DM: Biliary lipid secretion and bile composition after acute and chronic interruption of the enterohepatic circulation in the rhesus monkey. IV. Primate biliary physiology. J Clin Invest 50:1917-1926, 1971
16. Carulli N, Loria T, Bertoletti M, Ponz deLeon M, Menozzi D, Medici G, Piccagli I: Effects of acute changes in bile acid pool composition on biliary lipid composition. J Clin Invest 74:614-624, 1984
17. DenBesten L, Safaie-Shirazi S, Connor WE, Bell S: Early changes in bile composition and gallstone formation induced by a high cholesterol diet in prairie dogs. Gastroenterology 66:1036-1045, 1974
18. Roslyn JJ, Thompson JE Jr, DenBesten L: Anesthesia for prairie dogs. Lab Anim Sci 29:542-544, 1979
19. Anderegg C, Flaschka H, Sallman R, Schwarzenback GM: Metallindikatoren IV: Ein auf erdkaliionen ansprechendes phtalein und seine analytische Verwendung. Helv Chim Acta 37:113-120, 1951
20. Connerty H, Briggs A: Determination of serum calcium by means of orthocresolphthalein complexone. Am J Clin Pathol 45:290-296, 1966
21. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ: Protein measurement with the Folin phenol reagent. J Biol Chem 193:265-275, 1951
22. Röschlau P, Bernt E, Gruber W: Cholesterol and esterified cholesterol. In Methods of Enzymatic Analysis, Vol 4. New York, Academic Press, 1974, pp 1890-1893
23. Dryer RL, Tammes AR, Routh JI: The determination of phosphorus and phosphatase with N-phenyl-p-phenylenediamine. J Biol Chem 225:177-183, 1957
24. Iwata T, Yamasaki K: Enzymatic determination and TLC of bile acids in blood. J Biochem (Tokyo) 56:424-429, 1969
25. Carey MC: Critical tables for calculating the cholesterol saturation of native bile. J Lipid Res 19:945-955, 1978
26. Nakayama F, Nakagaki M: Class separation of bile lipids by thin-layer chromatography. J Chromatogr 183:287-293, 1980
27. Abedin MZ, Strichartz SD, Festekdjian S, Roslyn JJ: Increased Biliary calcium in cholesterol and pigment gallstone disease: the role of altered bile acid composition. Lipids 24(7):572-578, 1989
28. Chafouleas JG, Dedman JR, Munjaal RP, Means AR: Calmodulin: development and application of a sensitive radioimmunoassay. J Biol Chem 254(20):10262-10267, 1979
29. Vladutriu GD: Calmodulin quantitation in cystic fibrosis. IRCS Med Sci 12:515-516, 1984
30. Wallace RW, Cheung WY: Calmodulin: production of an antibody in rabbit and development of a radioimmunoassay. J Biol Chem 254(14):6564-6571, 1979
31. Wolf P, Hall C, Kilbourn JP: Determination of calcitonin and calmodulin by immuniperoxidase in the cystic fibrosis lung. Clin Invest 89:327-330, 1980
32. Gnegy ME, Erickson RP, Markovac J: Increased calmodulin in cultured skin fibroblasts from patients with cystic fibrosis. Biochem Med 26:294-298, 1981
33. Jebbink MCCW, Heijerman HGM, Masclee AAM, Lamers CBHW: Gallbladder disease in cystic fibrosis. Neth J Med 41:123-126, 1992
34. Roy CC, Weber AM, Morin CL, Combes JC, Nusslé D, Megevand A, Lasalle R: Abnormal biliary lipid composition in cystic fibrosis. Effect of pancreatic enzymes. N Engl J Med 297:1302-1305, 1977
35. Erlinger S: Cystic Fibrosis: bile secretion. Br Med Bull 48(4):860-876, 1992
36. Tera H: Stratification of human gallbladder bile in vivo. Acta Chir Scand Suppl 256:1, 1960
37. Schoenfield LJ, Sjoevall J: Bile acids and cholesterol in guinea pigs with induced gallstones. Am J Physiol 211:1069-1074, 1966
38. Klinkspoor JH, Kuver R, Savard CE, Oda D, Azzouz H, Tytgat GN, Groen AK, Lee SP: Model bile and bile salts accelerate mucin secretion by cultured dog gallbladder epithelial cells. Gastroenterology 109(1):264-274, 1995
39. Means AR, Putkey JA, Simmen RC, Berchtold MW: In Neurobiology: Molecular Biological Approaches to Understanding Neuronal Function and Development. P O'Lague (ed). New York, Alan R. Liss, 1985, pp 169-177
40. Rasmussen CD, Means AR: Calmodulin is involved in regulation of cell cycle progression. EMBO J 6(13):3961-3968, 1987
41. Ribar TJ, Jan CR, Augustine GJ, Means AR: Defective glycolysis and calcium signaling underlie impaired insulin secretion in a transgenic mouse. J Biol Chem 270(48):28688-26895, 1995
42. Cohen DE, Leonard MR, Carey MC: In vitro evidence that phospholipid secretion into bile may be coordinated intracellularly by the combined actions of bile salts and the specific phosphatidylcholine transfer protein of liver. Biochemistry 34:9975-9980, 1994
43. Chamberlain LH, Roth D, Morgan A, Burgoyne RD: Distinct effects of alpha-SNAP, 14-3-3 proteins, and calmodulin on priming and triggering of regulated exocytosis. J Cell Biol 130(5):1063-1070, 1995
44. Gardner B, Chenouda MS: Studies of bile acid secretion by isolated rat hepatocytes. J Lipid Res 19:985-991, 1978
45. Oude Elferink RPJ, Ottenhoff R, van Wijland M, Smit JJM, Schinkel AH, Groen AK: Regulation of biliary lipid secretion by mdr2 p-glycoprotein in the mouse. J Clin Invest 95:31-38, 1995
46. Secknus R, Yamashita G, Ginanni-Coorradini S, Chernosky A, Williams C, Hays L, Secknus MA, Holzbach RT: Purification and characterization of a novel 15 kd cholesterol crystallization inhibitor protein in bile. J Lab Clin Med 127(2):169-178, 1996
47. Lipsett PA, Hildreth J, Kaufman HS, Lillemoe KD, Pitt HA: Human gallstones contain pronucleating nonmucin glycoproteins that are immunoglobulins. Ann Surg 219(1):25-33, 1994