Synthesis of some 3-arylamino-5-aryloxymethyl[1,2,4]triazole derivatives and their antimicrobial activity

Pharmaceutica Acta Helvetiae

Volumn 72, Issue 5, 1998, Pages 285-290

  Demirayak, Şeref ^a   Benkli, Kadriye ^a   Güven, Kiymet ^b  

^a ANADOLU UNIVERSITY   (Turkey)

^b Faculty of Science   (Turkey)

Author keywords

3 Amino 1,2,4 triazole; Antimicrobial activity; Hydrazide; Thiourea

Indexed keywords

3 ARYLAMINO 5 ARYLOXYMETHYL[1,2,4]TRIAZOLE DERIVATIVE; ANTIBIOTIC AGENT; ANTIFUNGAL AGENT; CHLORAMPHENICOL; FLUCONAZOLE; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIFUNGAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; DRUG SYNTHESIS; INFRARED SPECTROMETRY; MASS SPECTROMETRY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE;

ANTI-INFECTIVE AGENTS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; SPECTROPHOTOMETRY, ULTRAVIOLET; STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZOLES;

EID: 0031915144     PISSN: 00316865     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0031-6865(97)00035-6     Document Type: Article

References (17)

1. Allen, C.F.H., VanAllan, J., Bachmann, W.E., Mac Naughton, N.W., 1955. 2-Amino-6-methylbenzothiazole. Org. Slynth. Coll. 3, 76.
2. 1 Isolamtidin und analoge. Arch. Pharm. 320, 608.
3. Demirayak, Ş., Evren, N., Ertan, M., 1990. Synthesis of [(4-phenyl-5-aryloxymethyl-4H-1,2,4-triazole-3-yl)thiol]-acetic acid or 2-propanoic acid and their ethyl ester derivatives as possible anti-inflammatory agents. Acta Pharm. Turc. 32, 35.
4. Dodson, R.M., Ross, F., 1950. Preparation of 2-alkylthioimidazoles. J. Am. Chem. Soc. 72, 1478.
5. Feierabend, J., Schubert, B., 1978. Comparative investigation of the action of several chlorosis-inducing herbicides on the biogenesis of chloroplasts and leaf microbodies. Pharm. Physiol. 61, 1017.
6. Finegold, S.M., Martin, W.J., Scott, E.G., 1978. Bailey and Scott's Diagnostic Microbiology. C.V. Mosby Company, St. Louis.
7. Inamori, M., Horii, T., Shimazu, T., Tugaya, M., 1988. Phenyltriazole Derivatives as Insecticides and their Preparation. Eur. Pat. EP 285,893 (C.A: 110:154303c).
8. Jennings, A.L., Boggs, J.E., 1964. Mass spectrometry for structure determination. Simple nitrogen heterocycles. J. Org. Chem. 29, 2065.
9. 2-receptor antagonists. J. Med. Chem. 28, 1628.
10. Lythgoe, D.J., Ramsden, C.A., 1994. 4-Unsubstituted 5-amino and 5-unsubstituted 4-aminoimidazoles. Adv. Heterocyclic Chem. 61, 1.
11. Ram, V.J., 1978. R(+)-1,2-bis(4-substituted-1,2,4-triazohne-5-thione-3-yl)glycol and related compounds as potential pesticides. Arch. Pharm. 311, 968.
12. Ram, V.J., Pandey, H.N., 1974. Synthesis of 5-membered heterocycles and related compounds. Chem. Pharm. Bull. 22, 2778.
13. Rasmussen, C.R., Villani, F.J., Weaner, L.E., Reynolds, B.E., Hood, A.R., Hecker, L.R., Nortey, S.O., Hanslin, A., Costanzo, M.J., Powell, E.T., Molinari, A.J., 1988a. Improved procedures for the preparation of cycloalkyl-, arylalkyl- and arylthioureas. Synthesis, 456.
14. Rasmussen, C.R., Villani, F.J., Reynolds, B.E., Plampin, J.N., Hood, A.R., Hecker, L.R., Nortey, S.O., Hanslin, A., Costanzo, M.J., Howse, R.M., Molinari, A.J., 1988b. A versatile synthesis of novel N,N,N″-trisubstituted guanidines. Synthesis, 460.
15. Reader, S.C.J., Carroll, B., Robertson, W.R., Lambert, A., 1987. Assessment of the biopotency of anti-thyroid drugs using porcine thyroid cells. Biochem. Pharmacol. 36, 1825-1828.
16. Sidwell, R.W., Huffman, J.H., Khare, G.P., Allen, L.B., Witkowski, J.T., Robins, R.K., 1972. Broad-spectrum antiviral activity of virazole: 1-β-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide. Science 177, 705.
17. Yale, H.L., Losee, K., Martins, J., Holsing, M., Perry, F.M., Bernstein, J., 1953. Chemotherapy of experimental tuberculosis. (V). Isonicotinic acid hydrazide and related compounds. J. Am. Chem. Soc. 75, 1933.