메뉴 건너뛰기




Volumn 97, Issue 2, 1998, Pages 211-218

Toward a new frontier in myocardial reperfusion therapy: Emerging platelet preeminence

Author keywords

Coronary thrombus; Fibrinolytic theraphy; Myocardial referfusion; Platelets; Thrombolytic theraphy

Indexed keywords

ABCIXIMAB; ACETYLSALICYLIC ACID; ANTITHROMBOCYTIC AGENT; EPTIFIBATIDE; FIBRINOGEN RECEPTOR ANTAGONIST; HEPARIN; HIRUDIN; LAMIFIBAN; LEFRADAFIBAN; ORBOFIBAN; SIBRAFIBAN; TICLOPIDINE; TIROFIBAN; TISSUE PLASMINOGEN ACTIVATOR; UNCLASSIFIED DRUG; WARFARIN; XEMILOFIBAN;

EID: 0031914990     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.97.2.211     Document Type: Review
Times cited : (273)

References (78)
  • 1
    • 0022640774 scopus 로고
    • Effectiveness of intravenous thrombolytic treatment in acute myocardial infarction
    • Gruppo Italiano per lo Studio della Streptochinasi nell'Infarto Miocardico (GISSI). Effectiveness of intravenous thrombolytic treatment in acute myocardial infarction. Lancet. 1986;1:397-401.
    • (1986) Lancet , vol.1 , pp. 397-401
  • 2
    • 0023805341 scopus 로고
    • Randomized trial of intravenous strep to kinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction
    • ISIS-2 (Second International Study of Infarct Survival) Collaborative Group. Randomized trial of intravenous strep to kinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction. Lancet. 1988;2:349-360.
    • (1988) Lancet , vol.2 , pp. 349-360
  • 3
    • 0028039957 scopus 로고
    • Indications for fibrinolytic therapy in suspected acute myocardial infarction: Collaborative overview of early mortality and major morbidity results from all randomized trials of more than 1000 patients
    • Fibrinolytic Therapy Trialists' (FTT) Collaborative Group. Indications for fibrinolytic therapy in suspected acute myocardial infarction: collaborative overview of early mortality and major morbidity results from all randomized trials of more than 1000 patients. Lancet. 1994;343:311-22.
    • (1994) Lancet , vol.343 , pp. 311-322
  • 4
    • 0029804941 scopus 로고    scopus 로고
    • ACC/AHA guidelines for the management of patients with acute myocardial infarction: Executive summary: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Acute Myocardial Infarction)
    • Ryan TJ, Anderson JL, Amman EM, Braniff BA, Brooks NH, Califf RM, Hillis LD, Hiratzka LF, Rapaport E, Teigel BJ, Russell RO, Smith EE, Weaver WD. ACC/AHA guidelines for the management of patients with acute myocardial infarction: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Acute Myocardial Infarction). Circulation. 1996;94:2341-2350.
    • (1996) Circulation , vol.94 , pp. 2341-2350
    • Ryan, T.J.1    Anderson, J.L.2    Amman, E.M.3    Braniff, B.A.4    Brooks, N.H.5    Califf, R.M.6    Hillis, L.D.7    Hiratzka, L.F.8    Rapaport, E.9    Teigel, B.J.10    Russell, R.O.11    Smith, E.E.12    Weaver, W.D.13
  • 5
    • 0027424433 scopus 로고
    • The effects of tissue plasminogen activator, streptokinase, or both on coronary artery patency, ventricular function, and survival after acute myocardial infarction
    • GUSTO Angiographie Investigators. The effects of tissue plasminogen activator, streptokinase, or both on coronary artery patency, ventricular function, and survival after acute myocardial infarction. N Engl J Med. 1993;329:1615-1622.
    • (1993) N Engl J Med , vol.329 , pp. 1615-1622
  • 6
    • 0028914981 scopus 로고
    • The link between the angiographie substudy and mortality outcomes in a large randomized trial of myocardial reperfusion: The importance of early and complete infarct artery reperfusion
    • Simes RJ, Topol EJ, Holmes DR, White HD, Rutsch WR, Vahanian A, Simoons ML, Morris D, Betriu A, Califf RM, Ross AM, for the GUSTO-I Investigators. The link between the angiographie substudy and mortality outcomes in a large randomized trial of myocardial reperfusion: the importance of early and complete infarct artery reperfusion. Circulation. 1995;91:1923-1928.
    • (1995) Circulation , vol.91 , pp. 1923-1928
    • Simes, R.J.1    Topol, E.J.2    Holmes, D.R.3    White, H.D.4    Rutsch, W.R.5    Vahanian, A.6    Simoons, M.L.7    Morris, D.8    Betriu, A.9    Califf, R.M.10    Ross, A.M.11
  • 7
    • 0027240597 scopus 로고
    • An international randomized trial comparing four thrombolytic strategies for acute myocardial infarction
    • The GUSTO Investigators. An international randomized trial comparing four thrombolytic strategies for acute myocardial infarction. N Engl J Med. 1993;329:673-682.
    • (1993) N Engl J Med , vol.329 , pp. 673-682
  • 9
    • 0030879325 scopus 로고    scopus 로고
    • An international, randomized comparison of reteplase with alteplase for acute myocardial infarction
    • GUSTO-III Investigators. An international, randomized comparison of reteplase with alteplase for acute myocardial infarction. N Engl J Med. 1997;337:1118-1123.
    • (1997) N Engl J Med , vol.337 , pp. 1118-1123
  • 10
    • 0030908055 scopus 로고    scopus 로고
    • A clinical trial comparing primary coronary angioplasty with tissue plasminogen activator and recomhinant himdin with heparin for acute myocardial infarction
    • The GUSTO II Angioplasty Substudy Investigators. A clinical trial comparing primary coronary angioplasty with tissue plasminogen activator and recomhinant himdin with heparin for acute myocardial infarction. N Engl J Med. 1997;336:1621-1928.
    • (1997) N Engl J Med , vol.336 , pp. 1621-1928
  • 13
    • 0027392814 scopus 로고
    • Immediate angioplasty compared with the administration of a thrombolytic agent followed by conservative treatment for myocardial infarction
    • Gibbons RJ, Holmes DR, Reeder GS, Bailey KR, Hopfenspirger MR, Gersh B. Immediate angioplasty compared with the administration of a thrombolytic agent followed by conservative treatment for myocardial infarction. N Engl J Med. 1993;328:685-691.
    • (1993) N Engl J Med , vol.328 , pp. 685-691
    • Gibbons, R.J.1    Holmes, D.R.2    Reeder, G.S.3    Bailey, K.R.4    Hopfenspirger, M.R.5    Gersh, B.6
  • 14
    • 0345513777 scopus 로고    scopus 로고
    • Primary coronary angioplasty vs. intravenous thrombolysis for treatment of acute myocardial infarction: A quantitative overview of their comparative effectiveness
    • In press
    • Weaver WD, Simes RJ, Betriu A, et al. Primary coronary angioplasty vs. intravenous thrombolysis for treatment of acute myocardial infarction: a quantitative overview of their comparative effectiveness. JAMA. In press.
    • JAMA
    • Weaver, W.D.1    Simes, R.J.2    Betriu, A.3
  • 15
    • 0029085210 scopus 로고
    • Direct angioplasty in acute myocardial infarction: State of the art and current controversies
    • 1.3
    • Horrigan MG, Topol EJ. Direct angioplasty in acute myocardial infarction: state of the art and current controversies. Cardiol Clin. 1995;1.3:321-338.
    • (1995) Cardiol Clin , pp. 321-338
    • Horrigan, M.G.1    Topol, E.J.2
  • 16
    • 0023224587 scopus 로고
    • A randomized trial of immediate versus delayed elective angioplasty after intravenous tissue plasminogen activator in acute myocardial infarction
    • Topol EJ, Califf RM, George BS, Kereiakes DJ, Abbottsmith CW, Candela RJ, Lee KL, Pitt B, Stack RS, O'Neill WW, for the Thrombolysis and Angioplasty in Myocardial Infarction Study Group. A randomized trial of immediate versus delayed elective angioplasty after intravenous tissue plasminogen activator in acute myocardial infarction. N Engl J Med. 1987;317:581-588.
    • (1987) N Engl J Med , vol.317 , pp. 581-588
    • Topol, E.J.1    Califf, R.M.2    George, B.S.3    Kereiakes, D.J.4    Abbottsmith, C.W.5    Candela, R.J.6    Lee, K.L.7    Pitt, B.8    Stack, R.S.9    O'Neill, W.W.10
  • 18
    • 0023771557 scopus 로고
    • Immediate vs delayed catheterization and angioplasty following thrombolytic therapy for acute myocardial infarction: TIMI II A results
    • TIMI Research Group. Immediate vs delayed catheterization and angioplasty following thrombolytic therapy for acute myocardial infarction: TIMI II A results. JAMA. 1988;260:2849-2858.
    • (1988) JAMA , vol.260 , pp. 2849-2858
  • 19
    • 0024428375 scopus 로고
    • Reperfusion momentum: Lessons from the randomized trials of immediate coronary angioplasty for acute myocardial infarction
    • Holmes DR, Topol EJ. Reperfusion momentum: lessons from the randomized trials of immediate coronary angioplasty for acute myocardial infarction. J Allergy Clin Immunol. 1989;14:1572-1578.
    • (1989) J Allergy Clin Immunol , vol.14 , pp. 1572-1578
    • Holmes, D.R.1    Topol, E.J.2
  • 20
    • 0025978544 scopus 로고
    • SWIFT trial of delayed elective intervention v conservative treatment after thrombolysis with anistreplase in acute myocardial infarction
    • SWIFT Trial Study Group. SWIFT trial of delayed elective intervention v conservative treatment after thrombolysis with anistreplase in acute myocardial infarction. BMJ. 1991;302:555-560.
    • (1991) BMJ , vol.302 , pp. 555-560
  • 21
    • 0026599237 scopus 로고
    • Plasma fibrinopeptide A levels in patients with acute myocardial infarction treated with alteplase: Correlation with concomitant heparin, coronary artery patency, and recurrent ischemia
    • Rapold JH, de Bono D, Arnold AER, Arnout J, DeCock F, Collen D, Verstraete M. for the European Cooperative Study Group. Plasma fibrinopeptide A levels in patients with acute myocardial infarction treated with alteplase: correlation with concomitant heparin, coronary artery patency, and recurrent ischemia. Circulation. 1992;85:928-934.
    • (1992) Circulation , vol.85 , pp. 928-934
    • Rapold, J.H.1    De Bono, D.2    Arnold, A.E.R.3    Arnout, J.4    DeCock, F.5    Collen, D.6    Verstraete, M.7
  • 22
    • 0025943594 scopus 로고
    • Plasma levels of plasminogen activator inhibitor type 1, B-thromboglobulin and fibrinopeptide A before, during and after treatment of acute myocardial infarction with alteplase
    • Rapold HJ, Brimaudo V, Declerck PJ, Kruithof KO, Bachmann F. Plasma levels of plasminogen activator inhibitor type 1, B-thromboglobulin and fibrinopeptide A before, during and after treatment of acute myocardial infarction with alteplase. Blood. 1991;78:1490-1495.
    • (1991) Blood , vol.78 , pp. 1490-1495
    • Rapold, H.J.1    Brimaudo, V.2    Declerck, P.J.3    Kruithof, K.O.4    Bachmann, F.5
  • 27
    • 0019504566 scopus 로고
    • Release of prostaglandins and thromboxane into the coronary circulation in patients with ischemic heart disease
    • Hirsh PD, Hillis CD, Campbell WB, Firth BG, Willerson JT. Release of prostaglandins and thromboxane into the coronary circulation in patients with ischemic heart disease. N Engl J Med. 1981;304:685-691.
    • (1981) N Engl J Med , vol.304 , pp. 685-691
    • Hirsh, P.D.1    Hillis, C.D.2    Campbell, W.B.3    Firth, B.G.4    Willerson, J.T.5
  • 28
    • 0022628119 scopus 로고
    • Speculation regarding mechanisms responsible for acute ischemic heart disease syndromes
    • Willerson JT, Hillis LD, Winniford M, Buja M. Speculation regarding mechanisms responsible for acute ischemic heart disease syndromes. J Allergy Clin Immunol. 1986;8:245-250.
    • (1986) J Allergy Clin Immunol , vol.8 , pp. 245-250
    • Willerson, J.T.1    Hillis, L.D.2    Winniford, M.3    Buja, M.4
  • 32
    • 0025187574 scopus 로고
    • Endogenous prostaglandin endoperoxides and prosracyclin modulate the thrombolytic activity of tissue plasminogen activator
    • Golino P, Rosolowsky M, Yao SK, McNatt J, DeClerck F, Buja LM, Willerson JT. Endogenous prostaglandin endoperoxides and prosracyclin modulate the thrombolytic activity of tissue plasminogen activator. J Clin Invest. 1990;86:1095-1102.
    • (1990) J Clin Invest , vol.86 , pp. 1095-1102
    • Golino, P.1    Rosolowsky, M.2    Yao, S.K.3    McNatt, J.4    DeClerck, F.5    Buja, L.M.6    Willerson, J.T.7
  • 33
    • 0025892010 scopus 로고
    • Is thrombolysis alone the best therapy for acute myocardial infarction?
    • Golion P, Willerson JT. Is thrombolysis alone the best therapy for acute myocardial infarction? Texas Heart Inst J. 1991;18:50-61.
    • (1991) Texas Heart Inst J , vol.18 , pp. 50-61
    • Golion, P.1    Willerson, J.T.2
  • 34
    • 0028519887 scopus 로고
    • Conner Memorial Lecture. Mechanisms leading to myocardial infarction: Insights from studies of vascular biology
    • Fuster V. Lewis A. Conner Memorial Lecture. Mechanisms leading to myocardial infarction: insights from studies of vascular biology. Circulation. 1994;90:2126-2146.
    • (1994) Circulation , vol.90 , pp. 2126-2146
    • Fuster, V.1    Lewis, A.2
  • 35
    • 0027125530 scopus 로고
    • The pathogenesis of coronary artery disease and the acute coronary syndromes
    • Fuster V, Badimon L, Badimon JJ, Chesebro JH. The pathogenesis of coronary artery disease and the acute coronary syndromes. N Engl J Med. 1992;326:242-250.
    • (1992) N Engl J Med , vol.326 , pp. 242-250
    • Fuster, V.1    Badimon, L.2    Badimon, J.J.3    Chesebro, J.H.4
  • 38
    • 0028087616 scopus 로고
    • Caveats about elective coronary stenring
    • Topol EJ. Caveats about elective coronary stenring. N Engl J Med. 1994;331:539-541.
    • (1994) N Engl J Med , vol.331 , pp. 539-541
    • Topol, E.J.1
  • 39
    • 0029113980 scopus 로고
    • The stentor and the sea change
    • Topol EJ. The stentor and the sea change. Am J Cardiol. 1995;76:307- 308.
    • (1995) Am J Cardiol , vol.76 , pp. 307-308
    • Topol, E.J.1
  • 44
    • 2242477091 scopus 로고
    • Use of a monoclonal antibody directed against the platelet glycoprotein IIb/IIIa receptor in high-risk coronary angioplasty
    • The EPIC Investigators. Use of a monoclonal antibody directed against the platelet glycoprotein IIb/IIIa receptor in high-risk coronary angioplasty. N Engl J Med. 1994;330:956-961.
    • (1994) N Engl J Med , vol.330 , pp. 956-961
  • 45
    • 1842369101 scopus 로고    scopus 로고
    • Effect of the platelet glycoprotein IIb/IIIa receptor inhibitor abciximab with lower heparin dosages on ischemic complications of percutaneous coronary revasculanzation
    • EPILOG Invesngators. Effect of the platelet glycoprotein IIb/IIIa receptor inhibitor abciximab with lower heparin dosages on ischemic complications of percutaneous coronary revasculanzation. N Engl J Med. 1997;336:1689-1696.
    • (1997) N Engl J Med , vol.336 , pp. 1689-1696
  • 46
    • 0029798675 scopus 로고    scopus 로고
    • Glycoprotein IIb/IIIa receptor inhibitors: Putting the EPIC, IMPACT II, RESTORE, and EPILOG trials into perspective
    • Tcheng JE. Glycoprotein IIb/IIIa receptor inhibitors: putting the EPIC, IMPACT II, RESTORE, and EPILOG trials into perspective. Am J Cardiol. 1996;78(suppl 3A):35-40.
    • (1996) Am J Cardiol , vol.78 , Issue.SUPPL. 3A , pp. 35-40
    • Tcheng, J.E.1
  • 47
    • 0000656559 scopus 로고    scopus 로고
    • Effects of competitive platelet glycoprotein IIb/IIIa inhibition with Integrilm in reducing complications ot percutaneous coronary intervention
    • The IMPACT II Investigators. Effects of competitive platelet glycoprotein IIb/IIIa inhibition with Integrilm in reducing complications ot percutaneous coronary intervention. Lancet. 1997;349:1422-1428.
    • (1997) Lancet , vol.349 , pp. 1422-1428
  • 48
    • 0345082238 scopus 로고    scopus 로고
    • Chimeric 7E3 AntiPlatelet in Unstable Angina Refractory to Standard Treatment (CAPTURE)
    • Birmingham. UK, August
    • Simoons M. Chimeric 7E3 AntiPlatelet in Unstable Angina Refractory to Standard Treatment (CAPTURE). Presented at the European Society- of Cardiology, Birmingham. UK, August 1996.
    • (1996) European Society- of Cardiology
    • Simoons, M.1
  • 49
    • 0000440354 scopus 로고    scopus 로고
    • A randomized trial of potent platelet IIb/IIIa antagonism, heparin or both in patients with unstable angina: The PARAGON Study
    • Abstract
    • PARAGON Investigators. A randomized trial of potent platelet IIb/IIIa antagonism, heparin or both in patients with unstable angina: the PARAGON Study. Circulation. 1996;94:I-553. Abstract.
    • (1996) Circulation , vol.94
  • 50
    • 3542998294 scopus 로고    scopus 로고
    • Platelet Receptor Inhibition for Ischemic Syndrome Management study (PRISM)
    • Anaheim, Calif, March
    • White H. Platelet Receptor Inhibition for Ischemic Syndrome Management study (PRISM). Presented at the American College of Cardiology, Anaheim, Calif, March 1997.
    • (1997) American College of Cardiology
    • White, H.1
  • 51
    • 1842836754 scopus 로고    scopus 로고
    • Platelet Receptor Inhibition for Ischémie Syndrome Management Study (PRISM) Plus
    • Anaheim, Calif, March
    • Theroux P. Platelet Receptor Inhibition for Ischémie Syndrome Management Study (PRISM) Plus. Presented at the American College of Cardiology, Anaheim, Calif, March 1997.
    • (1997) American College of Cardiology
    • Theroux, P.1
  • 52
    • 85036603831 scopus 로고    scopus 로고
    • Platelet IIb/IIIa Underpinning the Receptor for Suppression of Unstable Ischemia Trial (PURSUIT)
    • Stockholm, Sweden, August 24-28
    • Platelet IIb/IIIa Underpinning the Receptor for Suppression of Unstable Ischemia Trial (PURSUIT). Presented at the XIX Congress of the European Society of Cardiology, Stockholm, Sweden, August 24-28, 1997.
    • (1997) XIX Congress of the European Society of Cardiology
  • 54
    • 0028120906 scopus 로고
    • Collaborative overview of randomized trials of antiplatelet therapy-I: Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients
    • Anciplatelet Trialists' Collaboration. Collaborative overview of randomized trials of antiplatelet therapy-I: prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients. BMJ. 1994;308:81-106.
    • (1994) BMJ , vol.308 , pp. 81-106
  • 57
    • 0026475623 scopus 로고
    • Inhibitors of the platelet glycoprotein IIb/IIIa receptor as conjunctive therapy for coronary artery thrombolysis
    • Coller BS. Inhibitors of the platelet glycoprotein IIb/IIIa receptor as conjunctive therapy for coronary artery thrombolysis. Coron Artery Dis. 1992;3:1016-1029.
    • (1992) Coron Artery Dis , vol.3 , pp. 1016-1029
    • Coller, B.S.1
  • 58
    • 0023838863 scopus 로고
    • Rapid and sustained coronary artery recanalization with combined bolus injection of recombinant tissue-type plasminogen activator and monoclonal antiplatelet GP IIb/IIIa antibody in a canine preparation
    • Gold HK, Coller BS, Yasuda T, Saito T, Fallon JT, Guerrero JL, Leinbach RC, Ziskind AA, Collen D. Rapid and sustained coronary artery recanalization with combined bolus injection of recombinant tissue-type plasminogen activator and monoclonal antiplatelet GP IIb/IIIa antibody in a canine preparation. Circulation. 1988;77:670-677.
    • (1988) Circulation , vol.77 , pp. 670-677
    • Gold, H.K.1    Coller, B.S.2    Yasuda, T.3    Saito, T.4    Fallon, J.T.5    Guerrero, J.L.6    Leinbach, R.C.7    Ziskind, A.A.8    Collen, D.9
  • 59
    • 0025689389 scopus 로고
    • Lysis of plasminogen activator-resistant platelet-rich coronary artery thrombus with combined bolus injection of recombinant tissue-type plasminogen activator and antiplatelet GP IIb/IIIa antibody
    • Yasuda T, Gold HK, Leinbach RC, Saito T, Guerrero JL, Jang IK, Holt R, Fallon JT, Collen D. Lysis of plasminogen activator-resistant platelet-rich coronary artery thrombus with combined bolus injection of recombinant tissue-type plasminogen activator and antiplatelet GP IIb/IIIa antibody. J Am Coll Cardiol. 1990;7:1728-1735.
    • (1990) J Am Coll Cardiol , vol.7 , pp. 1728-1735
    • Yasuda, T.1    Gold, H.K.2    Leinbach, R.C.3    Saito, T.4    Guerrero, J.L.5    Jang, I.K.6    Holt, R.7    Fallon, J.T.8    Collen, D.9
  • 60
    • 0025350512 scopus 로고
    • Acceleration of recombinant tissue-type plasminogen activator-induced thrombolysis and prevention of reocclusion by the combination of heparin and the Arg-Gly-Asp-containing peptide bitistatin in a canine model of coronary thrombosis
    • Shebuski RJ, Stabihto IJ, Sitko GR, Polokoff MH. Acceleration of recombinant tissue-type plasminogen activator-induced thrombolysis and prevention of reocclusion by the combination of heparin and the Arg-Gly-Asp-containing peptide bitistatin in a canine model of coronary thrombosis. Circulation. 1990;82:169-177.
    • (1990) Circulation , vol.82 , pp. 169-177
    • Shebuski, R.J.1    Stabihto, I.J.2    Sitko, G.R.3    Polokoff, M.H.4
  • 61
    • 0026020072 scopus 로고
    • Kistrin, a polypeptide platelet GP IIb/IIIa receptor antagonist, enhances and sustains coronary arterial thrombolysis with recombinant tissue-type plasminogen activator in a canine preparation
    • Yasuda T, Gold HK, Leinbach RC, Yaoita H, Fallon JT, Guerrero L, Napier MA, Bunting S, Collen D. Kistrin, a polypeptide platelet GP IIb/IIIa receptor antagonist, enhances and sustains coronary arterial thrombolysis with recombinant tissue-type plasminogen activator in a canine preparation. Circulation. 1991;83:1038-1047.
    • (1991) Circulation , vol.83 , pp. 1038-1047
    • Yasuda, T.1    Gold, H.K.2    Leinbach, R.C.3    Yaoita, H.4    Fallon, J.T.5    Guerrero, L.6    Napier, M.A.7    Bunting, S.8    Collen, D.9
  • 63
    • 0025737479 scopus 로고
    • Prevention of reocclusion following tissue-type plasminogen activator-induced thrombolysis by the RGD-containing peptide, echistatin, in a canine model of coronary thrombosis
    • Holahan MA, Mellott MJ, Garsky VM, Shebuski RJ. Prevention of reocclusion following tissue-type plasminogen activator-induced thrombolysis by the RGD-containing peptide, echistatin, in a canine model of coronary thrombosis. Pharmacology. 1991;42:340-348.
    • (1991) Pharmacology , vol.42 , pp. 340-348
    • Holahan, M.A.1    Mellott, M.J.2    Garsky, V.M.3    Shebuski, R.J.4
  • 64
    • 0030033884 scopus 로고    scopus 로고
    • Pharmacokinetics and phannacodynamics of TP-9201, a GP IIbIIIa antagonist, administered in combination with recombinant tissue-type plasminogen activator, heparin, and aspirin in beagles
    • Modi NB, Reynolds T, Baughman SA, Thomas DA, Paasch BD, Smith SY. Pharmacokinetics and phannacodynamics of TP-9201, a GP IIbIIIa antagonist, administered in combination with recombinant tissue-type plasminogen activator, heparin, and aspirin in beagles. J Cardiovasc Pharmacol. 1996;27:105-112
    • (1996) J Cardiovasc Pharmacol. , vol.27 , pp. 105-112
    • Modi, N.B.1    Reynolds, T.2    Baughman, S.A.3    Thomas, D.A.4    Paasch, B.D.5    Smith, S.Y.6
  • 65
    • 0028346254 scopus 로고
    • Combination of platelet fibrinogen receptor antagonist and direct antithrombin inhibitor at low doses markedly improves thrombolysis
    • Nicolmi FA, Lee P, Rios G. Kottke-Marchant K. Topol EJ. Combination of platelet fibrinogen receptor antagonist and direct antithrombin inhibitor at low doses markedly improves thrombolysis. Circulation. 1994;89: 1802-1809.
    • (1994) Circulation , vol.89 , pp. 1802-1809
    • Nicolmi, F.A.1    Lee, P.2    Rios, G.3    Kottke-Marchant, K.4    Topol, E.J.5
  • 66
    • 0027501062 scopus 로고
    • Effects of hepann. aspirin and a synthetic platelet glycoprotein IIb/IIIa receptor antagonist (Ro 43-5054) on coronary artery repertusion and reocclusion alter thrombolysis with tissue-type plasminogen activator in the dog
    • Roux SP, Tschopp TB, Kuhn H, Steiner B, Hadvary P. Effects of hepann. aspirin and a synthetic platelet glycoprotein IIb/IIIa receptor antagonist (Ro 43-5054) on coronary artery repertusion and reocclusion alter thrombolysis with tissue-type plasminogen activator in the dog. J Pharmacol Exp Ther. 1993;264:501-508.
    • (1993) J Pharmacol Exp Ther , vol.264 , pp. 501-508
    • Roux, S.P.1    Tschopp, T.B.2    Kuhn, H.3    Steiner, B.4    Hadvary, P.5
  • 67
    • 0027281977 scopus 로고
    • Effects of G4120, a Arg-Gly-Asp containing synthetic platelet glycoprotein IIb/IIIa receptor antagonist, on arterial and venous thrombolysis with recombinant tissue-type plasminogen activator in dogs
    • Rapold HJ, Gold HK, Wu Z, Napier M, Bunting S, Collen D. Effects of G4120, a Arg-Gly-Asp containing synthetic platelet glycoprotein IIb/IIIa receptor antagonist, on arterial and venous thrombolysis with recombinant tissue-type plasminogen activator in dogs. Fibrinilysis. 1993;7:248-256.
    • (1993) Fibrinilysis , vol.7 , pp. 248-256
    • Rapold, H.J.1    Gold, H.K.2    Wu, Z.3    Napier, M.4    Bunting, S.5    Collen, D.6
  • 68
    • 0027302232 scopus 로고
    • Intravenous and endobronchial administration of G4120, 3 cyclic Arg-Gly-Asp-containing platelet GPIIb/IIIa receptorblocking pentapeptide, enhances and sustains coronary arterial thrombolysis with rt-PA in a canine preparation
    • Yasuda T, Gold HK, Kohmura C, Guerrero L, Yaoita H, Fallon JT, Bunting S, Collen D. Intravenous and endobronchial administration of G4120, 3 cyclic Arg-Gly-Asp-containing platelet GPIIb/IIIa receptorblocking pentapeptide, enhances and sustains coronary arterial thrombolysis with rt-PA in a canine preparation. Arterioscler Thromb. 1993;13:738-747.
    • (1993) Arterioscler Thromb , vol.13 , pp. 738-747
    • Yasuda, T.1    Gold, H.K.2    Kohmura, C.3    Guerrero, L.4    Yaoita, H.5    Fallon, J.T.6    Bunting, S.7    Collen, D.8
  • 70
    • 0027373742 scopus 로고
    • A chimeric murine/human antibody Fab fragment directed against the platelet GP IIb/IIIa receptor enhances and sustains arterial thrombolysis with recombinant tissue-type plasminogen activator m baboons
    • Kohmura C, Gold HK, Yasuda T, Holdt R, Nedelman MA, Guerrero JL, Weisman HF, Collen D. A chimeric murine/human antibody Fab fragment directed against the platelet GP IIb/IIIa receptor enhances and sustains arterial thrombolysis with recombinant tissue-type plasminogen activator m baboons. Anenoscler Thromb. 1993;13:1837-1842.
    • (1993) Anenoscler Thromb , vol.13 , pp. 1837-1842
    • Kohmura, C.1    Gold, H.K.2    Yasuda, T.3    Holdt, R.4    Nedelman, M.A.5    Guerrero, J.L.6    Weisman, H.F.7    Collen, D.8
  • 71
    • 0030981950 scopus 로고    scopus 로고
    • Antiplatelet effect of FK633, a platelet glycoprotein IIb/IIIa antagonist, on thrombus formation and vascular patency after thrombolysis in the injured hamster carotid artery
    • Kaida T, Matsuno H, Niwa M, Kozawa O, Miyata H, Uematsu T. Antiplatelet effect of FK633, a platelet glycoprotein IIb/IIIa antagonist, on thrombus formation and vascular patency after thrombolysis in the injured hamster carotid artery. Thromb Haemost. 1997;77:562-567.
    • (1997) Thromb Haemost , vol.77 , pp. 562-567
    • Kaida, T.1    Matsuno, H.2    Niwa, M.3    Kozawa, O.4    Miyata, H.5    Uematsu, T.6
  • 72
    • 0027194452 scopus 로고
    • Profound inhibition of platelet aggregation with monoclonal antibody 7E3 Fab after thrombolytic therapy: Results of the Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) 8 pilot study
    • Kleiman NS, Ohman EM, Califf RM, George BS, Kereliakes D, Aguirre FV, Weisman H, Schaible T, Topol EJ. Profound inhibition of platelet aggregation with monoclonal antibody 7E3 Fab after thrombolytic therapy: results of the Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) 8 pilot study. J Allergy Clin Immunol. 1993;22:381-389.
    • (1993) J Allergy Clin Immunol , vol.22 , pp. 381-389
    • Kleiman, N.S.1    Ohman, E.M.2    Califf, R.M.3    George, B.S.4    Kereliakes, D.5    Aguirre, F.V.6    Weisman, H.7    Schaible, T.8    Topol, E.J.9
  • 76
    • 0030998690 scopus 로고    scopus 로고
    • Restoration of coronary flow in myocardial infarction by intravenous chimeric 7E3 antibody without exogenous plasminogen activators: Observations in animals and humans
    • Gold HK, Garabedian HD, Dinsmore RE, Guerrero LJ, Cigarroa JE, Palacios IF, Leinbach RC. Restoration of coronary flow in myocardial infarction by intravenous chimeric 7E3 antibody without exogenous plasminogen activators: observations in animals and humans. Circulation. 1997; 95:1755-1759.
    • (1997) Circulation , vol.95 , pp. 1755-1759
    • Gold, H.K.1    Garabedian, H.D.2    Dinsmore, R.E.3    Guerrero, L.J.4    Cigarroa, J.E.5    Palacios, I.F.6    Leinbach, R.C.7
  • 77
    • 0030004098 scopus 로고    scopus 로고
    • Effects of platelet glycoprotein IIb/IIIa receptor blockade by a chimeric monoclonal antibody improves acute and 6-month outcomes following PTCA for acute myocardial infarction: Insights from the EPIC Trial
    • Lefkovits J, Ivanhoe RJ, Califf RM, Bergekon BA, Anderson KM, Stoner GL, Weisman HF, Topol EJ, for the EPIC Invesrigators. Effects of platelet glycoprotein IIb/IIIa receptor blockade by a chimeric monoclonal antibody improves acute and 6-month outcomes following PTCA for acute myocardial infarction: insights from the EPIC Trial. Am J Cardiol. 1996;77:1045-1051.
    • (1996) Am J Cardiol , vol.77 , pp. 1045-1051
    • Lefkovits, J.1    Ivanhoe, R.J.2    Califf, R.M.3    Bergekon, B.A.4    Anderson, K.M.5    Stoner, G.L.6    Weisman, H.F.7    Topol, E.J.8
  • 78
    • 0009503448 scopus 로고    scopus 로고
    • RAPPORT: Outcomes in patients with acute myocardial infarction with abciximab and primary PTCA
    • Stockholm, Sweden
    • Topol EJ. RAPPORT: outcomes in patients with acute myocardial infarction with abciximab and primary PTCA. Presented at the XIX Congress of the European Society of Cardiology, Stockholm, Sweden.
    • XIX Congress of the European Society of Cardiology
    • Topol, E.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.