Structural features of the combining site region of Erythrina corallodendron lectin: Role of tryptophan 135

Protein Science

Volumn 7, Issue 1, 1998, Pages 52-63

  Adar, Rivka ^a   Moreno, Ernesto ^b,c   Streicher, Hansjörg ^a   Karlsson, Karl Anders ^b   Ångström, Jonas ^b   Sharon, Nathan ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

^c CENTER OF MOLECULAR IMMUNOLOGY   (Cuba)

Author keywords

Erythrina corallodendron lectin; Metal ion binding; Molecular dynamics simulations; N dansylgalactosaminide binding; Site directed mutagenesis

Indexed keywords

LECTIN;

AMINO ACID SEQUENCE; ARTICLE; ERYTHRINA; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

ERYTHRINA CORALLODENDRON;

EID: 0031914964     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1002/pro.5560070105     Document Type: Article

References (37)

1. Adar R, Sharon N. 1996. Mutational studies of the amino acids in the combining site of Erythrina corallodendron lectin. Eur J Biochem 239:668-674.
2. Arango R, Adar R, Rozenblatt S, Sharon N. 1992. Expression of Erythrina corallodendron lectin in Escherichia coli. Eur J Biochem 205:575-581.
3. Arango R, Rodriguez-Arango E, Adar R, Belenky D, Loontiens F, Rozenblatt S, Sharon N. 1993. Modification by site-directed mutagenesis of the specificity of Erythrina corallodendron lectin for galactose derivatives with bulky substituents at C-2. FEBS Lett 330:133-136.
4. Arango R, Rozenblatt S, Sharon N. 1990. Cloning and sequence analysis of the Erythrina corallodendron lectin cDNA. FEBS Lett 264:109-112.
5. Bock K, Breimer ME, Brignole A, Hansson GC, Karlsson KA, Larson G, Leffler H, Samuelsson BE, Strömberg N, Svanborg-Edén C, Thurin J. 1985. Specificity of binding of a strain of uropathogenic Escherichia coli to Galα1 → 4Gal-containing glycosphingolipids. J Biol Chem 260:8545-8551.
6. Bouckaert J, Loris R, Poortmans F, Wyns L. 1995. Crystallographic structure of metal-free concanavalin A at 2.5 Å resolution. Proteins Struct Fund Genet 23:510-524.
7. 2+ ions. Biochemistry 16:3883-3896.
8. De Boeck H, Loontiens FG, Lis H, Sharon N. 1984. Binding of simple carbohydrates and some N-acetyllactosamine-containing oligosaccharides to Erythrina cristagalli agglutinin as followed with a fluorescent indicator ligand. Arch Biochem Biophys 234:297-304.
9. Dessen A, Gupta D, Sabesan S, Brewer CF, Sacchetini C. 1995. X-ray structure of the soybean agglutinin cross-linked with a biantennary analog of the blood group I carbodyrate antigen. Biochemistry 34:4933-4942.
10. Emmerich C, Helliwell JR, Redshaw M, Naismith JH, Harrop SJ, Raftery J, Kalb (Gilboa) AJ, Yariv J, Dauter Z, Wison KS. 1994. High-resolution structures of single-metal-substituted concanavalin A: The Co, Ca-protein at 1.6 Å resolution and the Ni, Ca-protein at 2.0 Å. Acta Crystallogr D 50:749-756.
11. Fiedler K, Simons K. 1995. The role of N-glycans in the secretory pathway. Cell 81:309-312.
12. Halgren TA. 1995. Potential energy functions. Curr Opin Struct Biol 5:205-5210.
13. Hamelryck TW, Minh-Hoa DT, Poortmans F, Chrispeels MJ, Wyns L, Loris R. 1996. The crystallographic structure of phytohemagglutinin-L. J Biol Chem 271:20479-20485.
14. Higuchi R, Krummel B, Saiki RK. 1988. A general method of in vitro preparation and specific mutagenesis of DNA fragments: Study of protein and DNA interactions. Nucleic Acid Res 167:351-7367.
15. Horejsi V, Ticha M, Kocourek J. 1977. Determination of dissociation constants of lectin-sugar complexes by means of affinity electrophoresis. Biochim Biophys Acta 499:290-300.
16. Imberty A, Mikros E, Koca J, Mollicone R, Oriol R, Perez S. 1995. Computer simulation of histo-blood group oligosaccharides: Energy maps of all constituting disaccharides and potential energy surfaces of 14 ABH and Lewis carbohydrate antigens. Glycoconjugate J 12:331-349.
17. Jaffe CL, Ehrlich-Rogozinski S, Lis H, Sharon N. 1977. Transition metal requirements of soybean agglutinin. FEBS Lett 82:191-196.
18. Jordan ET, Goldstein IJ. 1994. The sequence of a second member of the lima bean lectin gene family and the expression and characterization of recombinant lectin in Escherichia coli. J Biol Chem 269:7674-7681.
19. Kinzy WR, Belenky DM, Loontiens FG, Sharon N. 1992. Synthesis of methyl α- and β-N-dansyl-D-galactosaminides, probes for the combining sites of N-acetyl-D-galactosamine-specific lectins. Glycoconjugate J 9:225-227.
20. 2+-concanavalin A complexes. Biochemistry 20:4251-4260.
21. Konami Y, Yamamoto K, Osawa T, Irimura T. 1995. A putative carbohydrate-binding domain of the lactose-binding Cytisus sessilifolius anti-H(O) lectin has a similar amino acid sequence to that of the L-fucose-binding Ulex europeus anti-H(O) lectin. Glycoconjugate J 12:128-134.
22. Loris R, Stas PPG, Wyns L. 1994. Conserved waters in legume lectin crystal structures. The importance of bound water for the sequence-structure relationship within the legume lectins. J Biol Chem 269:26722-26733.
23. Lotan R, Skutelsky E, Danon D, Sharon N. 1975. The purification, composition and specificity of the anti-T lectin from peanut (Arachis hypogaea). J Biol Chem 250:8515-8523.
24. Moreno E, Teneberg S, Adar R, Sharon N, Karlsson KA, Ångström J. 1997. Redefinition of the carbohydrate specificity of Erythrina corallodendron lectin based solid-phase binding assays and molecular modeling of native and recombinant forms obtained by site-directed mutagenesis. Biochemistry 36:4429-4437.
25. Nicolau C, Kalb AJ, Yariv J. 1969. Electron spin resonance study of the transition metal-binding site of concanavalin A. Biochim Biophys Acta 194: 71-73.
26. Reed GH, Cohn M. 1970. Electron paramagnetic resonance spectra of manganese (II)-protein complexes. J Biol Chem 245:662-667.
27. Rini JM. 1995. X-ray crystal structures of animal lectins. Anna Rev Biophys Biomol Struct 24:551-577.
28. Roche AC, Monsigny M. 1996. Trafficking of endogenous glycoproteins mediated by intracellular lectins: Facts and hypotheses. Chemtracts-Biochem Mol Biol 6:188-201.
29. Shaanan B, Lis H, Sharon N. 1991. Structure of a legume lectin with an ordered N-linked carbohydrate in complex with lactose. Science 254:862-866.
30. Sharon N, Lis H. 1989. Lectins. London: Chapman and Hall. 127 pp.
31. Sharon N, Lis H. 1990. Legume lectins - A large family of homologous proteins. FASEB J 4:3198-3208.
32. Srinivasan N, Rufino SD, Pepys MB, Wood SP, Blundell TL. 1996. A superfamily of proteins with the lectin fold. Chemtracts - Biochem Mol Biol 6:149-164.
33. Surolia A, Sharon N, Schwarz FP. 1996. Thermodynamics of monosaccharide and disaccharide binding to Erythrina corallodendron lectin. J Biol Chem 271:17697-17703.
34. Teneberg S, Ångström J, Jovall PÅ, Karlsson KA. 1994. Characterization of binding of Galβ4GlcNAc-specific lectins from Erythrina cristagalli and Erythrina corallodendron to glycosphingolipids. Detection, isolation and characterization of a novel glycosphingolipid of bovine buttermilk. J Biol Chem 269:8554-8563.
35. Weis W, Drickamer K. 1996. Structural basis of lectin-carbohydrate recognition. Annu Rev Biochem 65:441-473.
36. Yang JT, Wu CC, Martinez HM. 1986. Calculation of protein conformation from circular dichroism. Methods Enzymol 130:208-269.
37. Young NM, Watson DC, Yaguchi M, Adar R, Arango R, Rodriguez-Arango E, Sharon N, Blay PKS, Thibault P. 1995. C-terminal post-translational proteolysis of plant lectins and their recombinant forms expressed in Escherichia coli. J Biol Chem 270:2563-2570.