Molecular characterisation of tumour infiltrating lymphocytes in oral squamous cell carcinoma

Cancer Immunology Immunotherapy

Volumn 46, Issue 1, 1998, Pages 34-40

  Stephens, Mark ^a   Lim, Kenneth ^a   Stephens, Philip ^a   Thomas, David W ^a   Lim, Seah H ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

OSCC; T cell clonal expansion; TILs

Indexed keywords

CD3 ANTIGEN; CD56 ANTIGEN; CD8 ANTIGEN; HLA DR ANTIGEN; T LYMPHOCYTE RECEPTOR;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLONOGENESIS; FEMALE; GENETIC ANALYSIS; HISTOLOGY; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; LYMPHOCYTIC INFILTRATION; MALE; MOUTH CARCINOMA; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA; T LYMPHOCYTE; T LYMPHOCYTE RECEPTOR GENE; TUMOR ASSOCIATED LEUKOCYTE;

ADULT; AGED; AGED, 80 AND OVER; AMINO ACID SEQUENCE; BASE SEQUENCE; CARCINOMA, SQUAMOUS CELL; FEMALE; GENES, T-CELL RECEPTOR; HUMANS; LYMPHOCYTES, TUMOR-INFILTRATING; MALE; MOLECULAR SEQUENCE DATA; MOUTH NEOPLASMS; T-LYMPHOCYTE SUBSETS;

EID: 0031913796     PISSN: 03407004     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002620050457     Document Type: Article

References (12)

1. Brennan J, Mao L, Huban RH, Boyle JO, Eby YJ, Koch WM, Goodman SN, Sidransky D (1995) Molecular assessment of histopathological staging in squamous cell carcinoma of the head and neck. N Engl J Med 332:429
2. Bryne M (1991) Prognostic factors of various molecular and cellular features in oral squamous cell carcinoma. A review. J Oral Pathol Med 20:413
3. Caignard A, Dietrich PY, Morand V, Lim A, Pannetier C, Leridant AM, Hercend T, Even J, Kourilsky P, Triebel F (1994) Evidence for T cell clonal expansion in patients with squamous cell carcinomas of the head and neck. Cancer Res 54:1292
4. Chikamatsu K, Eura M, Nakano K, Kanzaki Y, Matsuoka H, Masuyama K, Ishikawa T (1994) Analysis of T cell receptor variability in fresh tumour-infiltrating lymphocytes from human head and neck cancer. Jpn J Cancer Res 85:626
5. Chomczynski P, Sacchi N (1987) Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156
6. Coleman S, Perera P, Fisher J, Hoy T, Burned AK, Lim SH (1995) Abnormal TCR Vb repertoire in chronic myeloid leukaemia. Brit J Haematol 90:358
7. Houbiers JGA, Nijman HW, van der Burg SH, Drijfhout JW, Kenemans P, van de Velde CJH, Brand A, Mombury F, Kast WN, Melief CJM (1993) In vitro induction of human cytotoxic T lymphocyte responses against peptides of mutant and wild-type p53. Eur J Immunol 23:2072
8. Jung S, Schluesener HJ (1991) Human T lymphocytes recognize a peptide of single point-mutated, oncogeic ras proteins. J Exp Med 173:273
9. Lim SH, Thomas DW, Coleman S, Stephens P (1996) T cell receptor Vβ repertoire of tumour infiltrating lymphocytes in oral squamous cells carcinoma. Cancer Immunol Immunother 42:69
10. Mouri T, Nakamura S, Ohyama Y, Matsuzaki G, Shinohara M, Kishihara K, Hiroki A, Oka M, Shirasuna K, Nomoto K (1996) T cell receptor Vα and Vβ gene usage by tumour-infiltrating lymphocytes in oral squamous cell carcinoma. Cancer Immunol Immunother 43: 10-18
11. Sakai E, Rikimaru K, Ueda M, Matsumoto Y, Ishii N, Enomoto S, Yamamoto H, Tsuchida N (1992) The p53 tumour-suppressor gene and ras oncogene mutations in oral squamous cell carcinoma. Int J Cancer 52:867
12. Thomas DW, Matthews JB, Patel V, Game SM, Prime SS (1995) Inflammatory cell infiltrate associated with primary and transplanted tumours in an inbred model of oral carcinogenesis. J Oral Pathol Med 24:23