An acidic modification of the cytoplasmic domain contributes to the charge heterogeneity of the MHC class I antigens

Immunogenetics

Volumn 47, Issue 5, 1998, Pages 381-389

  Balomenos, D ^a,b   Poretz, R D ^a  

^a RUTGERS UNIVERSITY   (United States)

^b UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

2 D PAGE; Glycan; H2; Histocompatibility; Phosphorylation

Indexed keywords

GLYCOPROTEIN; H2 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PAPAIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; LYMPHOMA CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN MODIFICATION;

AMINO ACID SEQUENCE; ANIMALS; CELL CULTURE TECHNIQUES; CYTOPLASM; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ELECTROSTATICS; GLYCOPROTEINS; H-2 ANTIGENS; IMMUNOGLOBULIN HEAVY CHAINS; MICE; MOLECULAR SEQUENCE DATA; N-ACETYLNEURAMINIC ACID; NEURAMINIDASE; PAPAIN; PEPTIDE FRAGMENTS; PHOSPHORYLATION; PHOSPHOSERINE; PROTEIN ISOFORMS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; TIME FACTORS; TUMOR CELLS, CULTURED;

EID: 0031913362     PISSN: 00937711     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002510050373     Document Type: Article

References (42)

1. Archibald, A. L., Thompson, N. A., and Kvist, S. A single nucleotide difference at the 3' end of an intron causes differential splicing of two histocompatibility genes. EMBO J 5: 957-965, 1986
2. Brodsky, F. M. Intracellular routes for antigen processing and presentation. Res Immunol 142: 453-458, 1991
3. Capps, G. G. and Zuniga, M. C. A double-labeling method for measuring induction of protein phosphorylation. Biotechniques 8: 62-69, 1990
4. Capps, G. G., Van Kampen, M., Ward, C. L., and Zuniga, M.C. Endocytosis of the class I major histocompatibility antigen via a phorbol myristate acetate-inducible pathway is a cell-specific phenomenon and requires the cytoplasmic domain. J Cell Biol 108: 1317-1329, 1989
5. Eichholtz, T., Vossebeld, P., van Overveld M., and Ploegh, H. Activation of protein kinase C accelerates internalization of transferrin receptor but not of major histocompatibility complex class I, independent of their phosphorylation status. J Biol Chem 267: 22490-22495, 1992
6. Guild, B. C. and Strominger J. L. Human and murine class 1 MHC antigens share conserved serine 335, the site of HLA phosphorylation in vivo. J Biol Chem 259: 9235-9240, 1984
7. Hart, G. W. The role of asparagine-linked oligosaccharides in cellular recognition by thymic lymphocytes. J Biol Chem 257: 151-158, 1982
8. Henning, R., Milner R. J., Rieske, K., Cunningham, B. A., and Edelman, G. M. Subunit structure, cell surface orientation, and partial amino-acid sequences of murine histocompatibility antigens. Proc Natl Acad Sci USA 73: 118-122, 1976
9. Hille, A. and Huttner, W. B. Occurrence of tyrosine sulfate in proteins - a balance sheet. Eur J Biochem 188: 587-596, 1990
10. 2 microglobulin. J Immunol 146: 1862-1867, 1991
11. Huttner, W. B. Protein tyrosine sulfation. TIBS 12: 361-363, 1987
12. Hynes, R. O. Alteration of cell surface proteins by viral transformation and proteolysis. Proc Natl Acad Sci USA 70: 3170-3174, 1973
13. Jones, P. P. Analysis of H-2 and Ia antigens by two-dimensional polyacrylamide gel electrophoresis. Methods Enzymol 108: 452-466, 1984
14. Kemp, B. E. and Pearson, R. B. Protein kinase recognition sequence motifs. TIBS 15: 342-346, 1990
15. Lew, A. M., McCluskey, J., Maloy, W. L., Margulies, D. H., and Coligan, J. E. Multiple class I molecules generated from single genes by alternative splicing of pre-mRNAs. Immunol Res 6: 117-132, 1987
16. Loube, S. R., Owen, M. C., and Crumpton, M. J. Human class I histocompatibility antigens (HLA-A,B,C). Biochem J 210: 79-87, 1983
17. Machy, P., Truneh, A., Gennaro, D., and Hoffstein, S. Major histocompatibility complex class I molecules internalized via coated pits in T lymphocytes. Nature 328: 724-726, 1987
18. Maloy, W. L., Lew, A. M., Anderson, R. W., and Coligan, J. E. H-2 K molecules have two different C-termini, one of which is K-region specific. Mol Immunol 25: 453-463, 1988
19. d pre-mRNAs results in membrane expression of differentially phosphorylated protein products. EMBO J 5: 2477-2483, 1986
20. Moller, L. B., Kaufman, J., Verland, S., Salomonsen, J., Avila, D., Lambris, J. D., and Skjodt, K. Variations in the cytoplasmic region account for the heterogeneity of the chicken MHC class I (B-F) molecules. Immunogenetics 34: 110-120, 1991
21. Murre, C., Reiss, C. S., Bernabeu, C., Chen, L. B., Burakoff, S. J., and Seidman J. G. Construction, expression, and recognition of an H-2 molecule lacking its carboxyl terminus. Nature 307: 432-436, 1984
22. Nag, B., Arimilli, S., Koukis, B., Rhodes, E., Baichwal, V., and Sharma, D. Intramolecular charge heterogeneity in purified major histocompatability class II α and β polypeptide chains. J Biol Chem 269: 10061-10070, 1994
23. Nathenson, S. G., Uehara, H., Ewenstein, B. W., Kindt, T. J., and Coligan, J. E. Primary structural analysis of the transplantation antigens of the murine H-2 major histocompatibility complex. Annu Rev Biochem 50: 1025-1052, 1981
24. O'Farrell, P. H. High resolution two-dimensional electrophoresis of proteins. J Biol Chem 25: 4007-4021, 1975
25. Parham, P., Humphreys, R. E, Turner, M. J., and Strominger, J. L. Heterogeneity of HLA antigen preparations is due to variable sialic acid content. Proc Natl Acad Sci USA 71: 3998-4001, 1974
26. Pober, J. S., Guild, B. C., Strominger, J. L., and Veatch, W. R. Purification of HLA-A2 antigen, fluorescent labeling of its intracellular region, and demonstration of an interaction between fluorescently labeled HLA-A2 antigen and lymphoblastoid cell cytoskeleton proteins in vitro. Biochemistry 20: 5625-5633, 1981
27. Powell, L. D., Smith, K., and Hart, G. W. Site specific glycosylation patterns of H-2 K: Effects of allelic polymorphism and mitogenic stimulation. J Immunol 139: 1206-1213, 1987
28. Reichner, J. S., Whiteheart, S. W., and Hart, G. W. Intracellular trafficking of cell surface sialoglycoconjugates. J Biol Chem 263: 16316-16326, 1988
29. Reid, P. A. and Watts, C. Cycling of cell-surface MHC glycoproteins through primaquine-sensitive intracellular compartments. Nature 346: 655-657, 1990
30. k histocompatibility antigen. Proc Natl Acad Sci USA 7: 4239-4243, 1980
31. Shackelford, D. A. and Trowbridge, I. A. Identification of lymphocyte integral membrane proteins as substrates for protein kinase C. J Biol Chem 261: 8334-8341, 1986
32. Snider, M. D. and Rogers, O. C. Intracellular movement of cell surface receptor after endocytosis: resialylation of asialo-transferrin receptor in human erythroleukemia cells. J Cell Biol 10: 826-834, 1985
33. Springer, T. A. and Strominger, J. L. Detergent-soluble HLA antigens contain a hydrophilic region at the COOH-terminus and a penultimate hydrophobic region. Proc Natl Acad Sci USA 73: 2481-2485, 1976
34. Swiedler, S. J., Freed, J. H., Tarentino, A. L., Plummer, Jr. T. H., and Hart, G. W. Oligosaccharide microheterogeneity of the murine major histocompatibility antigens. J Biol Chem 260, 4046-4054, 1985
35. Swiedler, S. J., Hart, G. W., Tarentino, A. L., Plummer, Jr. T. H., and Freed, J. H. Stable oligosaccharide microheterogeneity at individual glycosylation sites of a murine major histocompatibility antigen derived from a B-cell lymphoma. J Biol Chem 258: 11515-11523, 1983
36. Turner, M. M., Cresswell, P., Parham, P., and Strominger, J. L. Purification of papain-solubilized histocompatibility antigens from a cultured human lymphoblastoid line, RPMI 4265. J Biol Chem 250: 4512-4519, 1975
37. Ueda, K. and Hayaishi, O. ADP-Ribosylation. Annu Rev Biochem 54: 73-100, 1985
38. Vega, M. A. and Strominger, J. L. Constitutive endocytosis of HLA class I antigens requires a specific portion of the intracytoplasmic tail that shares structural features with other endocytosed molecules. Proc Natl Acad Sci USA 86: 2688-2692, 1989
39. Wright, H. T. Nonenzymatic deamidation of asparaginyl and glutaminyl residues in proteins. Crit Rev Biochem Mol Biol 26: 1-52, 1991
40. Van, S. C. B., Grinnell, B. W., and Wold, F. Post-translational modifications of proteins: some problems left to solve. TIBS 14: 264-268, 1989
41. Zuniga, M. C. and Hood, L. E. Clonal variation in cell surface display of an H-2 protein lacking a cytoplasmic tail. J Cell Biol 102: 1-10, 1986
42. Zuniga, M. C., Malissen, B., McMillan, M., Brayton, P. R., Clark, S. S., Forman, J., and Hood, L. Expression and function of transplantation antigens with altered or deleted cytoplasmic domains. Cell 34: 535-544, 1983