Electrophysiology: A review of signal origins and applications to investigating glaucoma

Australian and New Zealand Journal of Ophthalmology

Volumn 26, Issue 1, 1998, Pages 71-85

  Graham, Stuart L ^a   Klistorner, Alexander ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Electroretinogram; Glaucoma; Multifocal stimulus; Pattern electroretinogram; Visual evoked response

Indexed keywords

ELECTROPHYSIOLOGY; ELECTRORETINOGRAM; EVOKED VISUAL RESPONSE; GLAUCOMA; HUMAN; OSCILLATORY POTENTIAL; REVIEW; SIGNAL PROCESSING;

ANIMALS; CATS; ELECTRORETINOGRAPHY; EVOKED POTENTIALS, VISUAL; GLAUCOMA; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; PHOTIC STIMULATION; VISUAL FIELDS;

EID: 0031913305     PISSN: 08149763     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1606.1998.00082.x     Document Type: Review

References (159)

1. Dewar J. The physiologic action of light. Mature 1877; 15: 433-5.
2. Riggs LA. Continuous and reproducible records of the electrical activity of the human retina. Proc. Soc. Exp. Biol. Med. 1941; 48: 204-7.
3. Karpe G. The basis of clinical electroretinography. Acta Ophthalmol. 1945; 24 1-118.
4. Rodieck RW. Components of the electroretinogram: A reappraisal. Vis. Res. 1972; 12: 773-80.
5. Granit R. Sensory mechanisms of the retina with an appendix on electroretinography. London: Oxford University Press, 1947.
6. Rodieck RW. The Vertebrate Retina. Principles of Structure and Function. San Francisco: WH Freeman and Co., 1973.
7. Dowling JE. Organization of the vertebrate retinas. Invest. Ophthalmol. 1970; 9: 655-80.
8. Kline RP, Ripps H, Dowling JE. Generation of b-wave currents in the skate retina. Proc. Natl Acad. Sci. USA 1978; 75: 5727-31.
9. + hypothesis. J. Neurophysiol 1984; 51: 164-82.
10. Stockton RA, Slaughter MM. B-wave of the electroretinogram: A reflection of ON bipolar cell activity. J. Gen. Physiol. 1989; 93: 101-22.
11. Karwoski CJ, Proenza LM. Relationship between Muller cell responses: A local transretinal potential and potassium flux. J Neurophysiol. 1977; 40: 244-59.
12. Marmor MF, Lurie M. Light-induced electrical responses of the retinal pigment epithelium. In: Zinn KM, Marmor MF, eds. The Retinal Pigment Epithelium. Cambridge, MA: Harvard University Press, 1979; 226-44.
13. Nagata M. Studies on the photopic ERG of the human retina. Jpn. J. Ophthalmol. 1963; 7: 96-124.
14. Dodt E, Wadenstein L. The use of flicker electroretinography in the human eye. Acta Ophthalmol. 1954; 32: 165.
15. Sandberg MA, Ariel M. A hand-held, two channel stimulator ophthalmoscope. Arch. Ophthalmol. 1978; 95: 1881-2.
16. Brindley GS, Westheimer G. Spatial properties of the human electroretinogram. J. Physiol. 1965, 179: 518-37.
17. Sieving PA, Steinberg RH. Contribution from proximal retina to intraretinal pattern ERG: The M-wave. Invest. Ophthalmol. Vis. Sci. 1985; 26: 1642-7.
18. Sieving PA, Frishman LJ, Steinberg RH. Scotopic threshold response of proximal retina in cat. J. Neurophysiol 1986; 56: 1049-61.
19. Sieving PA, Nino C. Scotopic threshold response of the human electroretinogram. Invest. Ophthalmol. Vis. Sci. 1988; 29: 1608-14.
20. Wakabayashi K, Gieser J, Sieving PA. Aspartate separation of the scotopic threshold response from the photoreceptor a-wave of the cat and monkey. Invest. Ophthalmol. Vis. Sci. 1988; 29: 1615-22.
21. 0 in proximal portion of the dark-adapted cat retina. J. Neurophysiol. 1989; 61: 1233-43.
22. Aylward GW. The STR in diabetic retinopathy. Eye 1989; 3: 626-37.
23. Graham SL, Vaegan. High correlation between psychophysical threshold and the scotopic threshold response (STR). Br. J. Ophthalmol. 1991; 75: 603-7.
24. Aylward GW, Vaegan, Billson FA. The scotopic threshold response. Clin. Vis. Sci. 1989; 4: 373-7.
25. Brown KT, Murakami M. A new receptor potential of the monkey retina with no detectable latency. Nature 1964; 201: 626-8.
26. Park WL, Cone RA. Isolation and identification of the initial peak of the early receptor potential. Nature 1965; 204: 836-8.
27. Goldstein EB, Berson EL. Rod and cone contributions to the human early receptor potential. Vis. Res. 1970; 10: 207-18.
28. Cobb WA, Morton HB. A new component of the human electroretinogram. J. Physiol. 1954; 123: P36-7.
29. Yonemura D. The oscillatory potential of the electroretinogram. Acta Soc. Ophthalmol. Jpn. 1962; 66: 1566-84.
30. Speros P, Price J. Oscillatory potentials: History, techniques and potential use in the evaluation of disturbances of the retinal circulation. Surv. Ophthalmol. 1981; 25: 237-52.
31. Peachey NS, Alexander KR, Fishman GA. Rod and cone system contributions to oscillatory potentials: An explanation for the conditioning flash effect. Vis. Res. 1987; 27: 859-66.
32. Ogden T. The oscillatory potentials of the primate electroretinogram. Vis. Res. 1973; 13: 1059-74.
33. Heynen H, Wachtmeister L, van Norren D. Origin of the oscillatory potentials in the primate retina. Vis. Res. 1985; 25: 1365-73.
34. Kojima M, Zrenner E. Off-components in response to brief light flashes in the oscillatory potential of the human electroretinogram. Graefes Arch. Clin. Exp. Ophthalmol. 1978; 206: 107-20.
35. King-Smith P, Loffing DH, Jones R. Rod and cone ERGs and their oscillatory potentials. Invest. Ophthalmol. Vis. Sci. 1986; 27: 270-3.
36. Wachtmeister L. Basic research and clinical aspects of the oscillatory potentials of the electroretinogram. Doc. Ophthal. 1987; 66: 187-94.
37. Miyake Y, Shiroyama N, Horiguchi M, Ota I. Asymmetry of focal ERG in human macular region. Invest. Ophthalmol. Vis. Sci. 1989; 30: 1743-9.
38. Lachapelle P. Analysis of the photopic electroretinogram recorded before and after dark adaptation. Can. J. Ophthalmol. 1987; 22: 354-61.
39. Wachtmeister L. Further studies of the chemical sensitivity of the oscillatory potentials of the electroretinogram (ERG). I. GABA and glycine antagonists. Acta Ophthalmol. 1980; 58: 712-25.
40. Wachtmeister L. Further studies of the chemical sensitivity of the oscillatory potentials of the electroretinogram (ERG). II. Glutamate, aspartate and dopamine antagonists. Acta Ophthalmol. 1981; 59: 247-58.
41. Riggs LA, Johnson EP, Schick AML. Electrical responses of the human eye to moving stimulus pattern-reversals. Science 1964; 144: 567-70.
42. Johnson EP, Riggs LA, Schick AML. Photopic retinal potentials evoked by phase alternation of a barred pattern. Vis. Res. 1966; 6: 75-9.
43. Maffei L, Fiorentini A. Electroretinographic responses to alternating gratings before and after section of the optic nerve. Science 1981; 211: 953-5.
44. Maffei L, Fiorentini A, Bisti S, Hollander H. Pattern ERG in the monkey after section of the optic nerve. Exp. Brain Res. 1985; 59: 423-5.
45. Fiorentini A, Maffei L, Pirchio M, Spinelli D, Porciatti V. The ERG in response to alternating gratings in patients with diseases of the peripheral visual pathway. Invest. Ophthalmol. Vis. Sci. 1981; 21: 490-3.
46. Arden CB, Vaegan, Hogg CR. Clinical and experimental evidence that the pattern electroretinogram (PERG) is generated in more proximal retinal layers than the focal electroretinogram (FERG). Ann. N.Y. Acad. Sci. 1982; 388: 580-607.
47. Baker CL, Hess RF, Olsen BT, Zrenner E. Current source density analysis of linear and non-linear components of the primate electroretinogram. J. Physiol. 1988; 407: 155-76.
48. Groneberg A, Teping C. Topodiagnostik von Sehstorungen durch Ableitung retinaler und kortikaler Antworten auf Umkehr-Kontrastmuster. Berlin. Deutsch. Ophthalmol. Ges. 1980; 77: 409-17.
49. Harrison JM, O'Connor PS, Young RSL, Kincaid M, Bentley R. The pattern ERG in man following surgical resection of the optic nerve. Invest. Ophthalmol. Vis. Sci. 1987, 28: 492-9.
50. Trick GL, Nesher R, Cooper DG, Shields SM. The human pattern ERG: Alteration of response properties with aging. Optom. Vis. Sci. 1992; 69: 122-8.
51. Odom JV, Maida T, Dawson WW. Pattern evoked retinal responses (PERR) in human: Effects of spatial frequency, luminance and defocus. Curr. Eye Res. 1982; 2: 99-108.
52. Korth M, Rix R, Sembritzki O. Spatial contrast transfer functions of the pattern evoked electroretinogram. Invest. Ophthalmol. Vis. Sci. 1985; 26: 303-8.
53. Drasdo N, Thompson DA, Thompson CM, Edward L. Complementary components and local variations of the pattern electroretinogram. Invest. Ophthalmol. Vis. Sci. 1987; 28: 158-62.
54. Thompson DA, Drasdo N. Computation of the luminance and pattern components of the bar pattern electroretinogram. Doc. Ophthalmol. 1987; 66: 233-44.
55. Sutler EE, Vaegan. Lateral interaction component and local luminance nonlinearities in the human pattern reversal ERG. Vis. Res. 1990; 30: 659-71.
56. Van den Berg TJ, Boltjes B, Spekreijse H. Pattern electroretinogram can be more than the sum of local luminance responses. Doc. Ophthalmol. 1988; 69: 307-14.
57. Arden G, Carter R, Macfarlan A. Pattern and Ganzfeld electroretinograms in macular disease. Br. J. Ophthalmol. 1984; 68: 878-84.
58. Lawwill T. The bar pattern electroretinogram for clinical evaluation of the central retina. Am. J. Ophthalmol. 1974; 78: 22-48
59. Berninger TA, Arden GB, Hogg CR, Frumkes T. Separable evoked retinal and cortical potentials from each major visual pathway: Preliminary results. Br. J. Ophthalmol. 1989; 73: 502-11.
60. Dawson WW, Parmer R, Hope GM, Trick GL. Excitation and inhibition of the pattern evoked retinal response in a foveate animal. Doc. Ophthalmol. 1984; 40: 11-20.
61. Trick GL, Wintermeyer DH. Spatial and temporal frequency tuning of pattern-reversal retinal potentials. Invest. Ophthalmol. Vis. Sci. 1982; 23: 774-9.
62. Dawson WW, Trick GL, Litzkow C. Improved electrode for electroretinography. Invest. Ophthalmol. Vis. Sci. 1979; 18: 988-91.
63. Arden GB, Carter RM, Hogg C, Siegel IM, Margolis S. A gold foil electrode: Extending the horizons for clinical electroretinography. Invest. Ophthalmol. Vis. Sci. 1979; 18: 421-6.
64. Steinberg RH, Linsenmeier RA, Griff ER. Three light-evoked responses of the retinal pigment epithelium. Vis. Res. 1983; 23: 1315-23.
65. Arden GB, Barrada A, Kelsey JH. New clinical test of retinal function based upon the standing potential of the eye. Br. J. Ophthalmol. 1962; 46: 449-67.
66. Riggs LA, Wooten BR. Electrical measures and psychophysical data on human vision. In: Jamison D, Hurvich LM, eds. Handbook of sensory physiology, Vol. 7. New York: Springer-Verlag, 1972; 690-731.
67. Bodis-Wollner I. Electrophysiological and psychophysical testing of vision in glaucoma. Surv. Ophthalmol. 1989; 33 (Suppl.): 301-7.
68. Schmeisser ET, Smith TJ. High-frequency flicker visual evoked potential losses in glaucoma. Ophthalmology 1989; 96: 620-3.
69. Ducatti A, Fava E, Motti EDF. Neuronal generators of the visual evoked potentials: Intracerebral recordings in awake humans. Electroencephalogr. Clin. Neurophysiol 1988; 71: 89-99.
70. Kraut MA, Arezzo JC, Vaughan HG. Intracortical generators of the flash VEP in monkey. Electroencephalogr Clin. Neurophysiol. 1985; 62: 300-12.
71. Maier J, Dagrielle G, Spekreije H, van Duk BW. Principal component analysis for source localisation of VEPs in man. Vis. Res. 1987; 27: 165-77.
72. Sokol S. The visually evoked cortical potential in optic nerve and visual pathway disorders. In: Fishman G, ed. Electrophysiological testing in disorders of the retina, optic nerve and visual pathway. San Francisco: American Academy of Ophthalmology, 1990; 105-41.
73. Simonsen SW. The value of the oscillatory potential in selecting juvenile diabetics at risk of developing proliferative retinopathy. Acta Ophthalmol. 1980; 58: 865-78.
74. Bresnick GH, Palta M. Predicting progression to severe proliferative diabetic retinopathy. Arch. Ophthalmol. 1987; 105: 810-14.
75. Bresnick GH, Palta M. Oscillatory potential amplitudes: Relation to severity of diabetic retinopathy. Arch. Ophthalmol. 1987; 105: 929-33.
76. Coupland SG. A comparison of pattern electroretinogram and oscillatory potential measures in diabetic retinopathy. Doc. Ophthalmol. 1987; 66: 207-18.
77. Arden GB, Hamilton AMP, Wilson-Holt J, Ryan S, Yudkin JS, Kurtz A. Pattern electroretinograms become abnormal when background diabetic retinopathy deteriorates to a pre-proliferative stage. Br J. Ophthalmol. 1986; 70: 330-5.
78. Coupland SG. A comparison of oscillatory potentials and pattern ERG measures in diabetic retinopathy. Doc. Ophthalmol. 1987; 66: 207-18.
79. Sabates R, Hirose T, McMeel JW. Electroretinography in the prognosis and classification of central retinal vein occlusion. Arch. Ophthalmol. 1983; 101: 232-5.
80. Barber C, Galloway NR, Reacher M. The role of the electroretinogram in the management of central retinal vein occlusion. Doc. Ophthalmol. Proc. Ser. 1984; 40: 149-59.
81. Leydhecker G. The electroretinogram in glaucomatous eyes. Br. J. Ophthalmol. 1950; 34: 550-4.
82. Henkes HE. Electroretinography: An evaluation of the influence of the retinal and general metabolic condition on the electrical responses of the retina. Am. J. Ophthalmol. 1957; 43: 67-81.
83. Francois J. L'electroretinographie dans le glaucome. Acta Ophthalmol. 1953; 31: 205-18.
84. Schmoger E, Zimmer W. Das Elektroretinogramm bei primarem Glaukom. Klin. Monatsbl. Augenheilkd 1965; 146: 122-3.
85. Wanger P, Persson H. Pattern reversal electroretinograms in unilateral glaucoma. Invest. Ophthalmol. Vis. Sci. 1982; 24: 749-53.
86. Johnson MA, Drum BA, Quigley HA, Sanchez RM, Dunkelberger GR. Pattern-evoked potentials and optic nerve fiber loss in monocular laser induced glaucoma. Invest. Ophthalmol. Vis. Sci. 1989; 30: 897-907.
87. Berson EL. Electrical phenomena in the retina. In: Moses RA, ed. Adler's Physiology of the Eye. St Louis: CV Mosby Co., 1981; 466-81.
88. Fiorentini A, Maffei L, Pirchio M, Porchiatti V, Spinelli D. Pattern ERG in patients with unilateral alterations of the retinal ganglion cells. Doc. Ophthalmol. Proc. Ser. 1982; 31: 131-3.
89. Uji Y, Yokoyama M. Blue-cone response in glaucomatous eyes studied with electroretinography. Doc. Ophthalmol. Proc. Ser. 1982; 31: 103 (Abstract).
90. Henkes HE. The electroretinogram in glaucoma. Ophthalmologica 1951; 121: 44-5.
91. Alvis DL. Electroretinographic changes in controlled chronic open-angle glaucoma. Am. J. Ophthalmol. 1966; 61: 121-31.
92. Lowitzsch K, Welt R. VEP und Elektroretinographie durch Musterumkehrreizung in der Fruhdiagnose des Glaucoma chronicum simplex. Z. EEG-EMG 1991; 22: 217-23.
93. Bartl G. Das Elektroretinogram und das evozierte Sehrindenpotential bei normalen and an Glaukom erdrankten Augen. Graefes Arch. Clin. Exp. Ophthalmol. 1978; 207: 243-69.
94. Khvatova AB, Kovalchuck NZ, Bogoslovsky AI. Infantile glaucoma: Electrophysiology. Acta Ophthalmol. 1979; 57: 637-42.
95. Halatek R, Kozjello T. ERG investigations of patients with congenital glaucoma. Klin. Oczna 1978; 48: 657-8.
96. Fazio DT, Heckenlively JR, Martin DA, Christensen RE. The electroretinogram in advanced open angle glaucoma. Doc. Ophthalmol. 1986; 63: 45-54.
97. Vass C, Menapace R, Gottlob I. Neranderungen des Helligkeits-Elektroretinogramms bei Patienten mit Glaucoma chronicum simplex. Spectrum Augenheilkd 1990; 4: 226-9.
98. Holopigian K, Seiple W, Mayron C, Koty R, Lorenzo M. Electrophysiological and psychophysical flicker sensitivity in patients with primary open angle glaucoma and ocular hypertension. Invest. Ophthalmol. Vis. Sci. 1990; 31: 1863-8.
99. Nao-l NFM, Nakazaki S, Liu M, Sawada A. Luminance electroretinogram in young patients with primary open angle glaucoma. Invest. Ophthalmol. Vis. Sci. 1994; 35: 581 (Abstract).
100. Vaegan, Graham SL, Goldberg I, Buckland L, Hollows FC. Flash and pattern electroretinogram changes with optic atrophy and glaucoma. Exp. Eye Res. 1995; 60: 697-706.
101. Graham SL, Drance SM, Chauhan BC et al. Comparison of psychophysical and electrophysiological testing in early glaucoma. Invest. Ophthalmol. Vis. Sci. 1996; 37: 2651-62.
102. Wachtmeister L, el Azazi M. Oscillatory potentials of the electroretinogram in patients with unilateral optic atrophy. Ophthalmologica 1985; 191: 39-50.
103. Gur M, Zeevi YY, Bielik M, Neumann E. Changes in the oscillatory potentials of the electroretinogram in glaucoma. Curr. Eye Res. 1987; 6: 457-66.
104. Brodie SE, Frisch S, Siebold E et al. Fourier analysis of the oscillatory potentials in glaucoma and ocular hypertension. Invest. Ophthalmol. Vis. Sci. 1988; 29: 239 (Abstract).
105. Vaegan, Graham SL, Goldberg I, Millar TJ. Selective reduction of oscillatory potentials and pattern electroretinograms after retinal ganglion cell damage by disease in humans or by kainic acid toxicity in cats. Doc. Ophthalmol. 1991; 77: 237-53.
106. Sieving PA. Retinal ganglion cell loss does not abolish the scotopic threshold response (STR) of the cat and human ERG. Clin. Vis. Sci. 1991; 6: 149-58.
107. Korth M, Nguyen NX, Horn F, Martus P. Scotopic threshold response and scotopic PIi in glaucoma. Invest. Ophthalmol. Vis. Sci. 1994; 35: 619-25.
108. Frishman LJ, Robson JG, Du L. Contributions of the positive and negative scotopic threshold responses to the scotopic cat ERG. Invest. Ophthalmol. Vis. Sci. 1993; 34: 1273 (Abstract).
109. Frishman LJ, Shen FF, Due L et al. The scotopic electroretinogram of macaque after retinal ganglion cell loss from experimental glaucoma. Invest. Ophthalmol. Vis. Sci. 1996; 37: 125-41.
110. Howe JW, Mitchell KW. Visual evoked potential changes in chronic glaucoma and ocular hypertension. Doc. Ophthalmol. 1986; 105: 457-62.
111. Motolko M, Drance SM, Douglas GR. The early psychophysical disturbances in chronic open-angle glaucoma. A study of visual functions with asymmetric disc cupping. Arch. Ophthalmol. 1982; 100: 1632-4.
112. Sokol S, Domar A, Moskovitz A, Schwarz B. Pattern evoked potential latency and contrast sensitivity in glaucoma and ocular hypertension. Doc. Ophthalmol. Proc. Ser. 1981; 27: 79-86.
113. Towle VL, Moskovitz A, Sokol S, Schwartz B. The visual evoked potential in glaucoma and ocular hypertension: Effects of check size, field size, and stimulation rate. Invest. Ophthalmol. Vis. Sci. 1983; 26: 175-83.
114. Mitchell KW. The visual evoked potential in the differential diagnosis of ocular hypertension and chronic simple glaucoma. PhD Thesis, University of Newcastle upon Tyne, United Kingdom. 1987.
115. Bray LC, Mitchell KW, Howe JW. Prognostic significance of the pattern visual evoked potential in ocular hypertension. Br. J. Ophthalmol. 1991; 75: 79-83.
116. Holder GE. Significance of abnormal pattern electroretinography in anterior visual pathway dysfunction. Br. j. Ophthalmol. 1987; 71: 166-71.
117. Korth M, Horn F, Storck B, Jonas J. The pattern-evoked electroretinogram (PERG): Age-related alterations and changes in glaucoma. Graefes Arch. Gin. Exp. Ophthalmol. 1989; 227: 123-30.
118. Weinstein C, Arden G, Hitchings R, Ryan S, Calthorpe C, Odom J. The pattern electroretinogram in ocular hypertension and glaucoma. Arch. Ophthalmol. 1988; 106: 923-8.
119. O'Donaghue E, Arden GB, O'Sullivan F et al. The pattern electroretinogram in glaucoma and ocular hypertension. Br. J. Ophtahlmol. 1992; 76: 387-94.
120. Wanger P, Persson HE. Pattern-reversal electroretinograms and high-pass resolution perimetry in suspected or early glaucoma. Ophthalmology 1987; 94: 1098-103.
121. Trick G. Pattern reversal retinal potentials in ocular hypertensives at high and low risk of developing glaucoma. Doc. Ophthalmol. 1987; 65: 79-85.
122. Pfeiffer N, Tillmon B, Bach M. Predictive value of the pattern electroretinogram in high-risk ocular hypertension. Invest. Ophtahlmol. Vis. Sci. 1993; 34: 1710-15.
123. Bach M, Hiss P, Rover J. Check-size specific changes of pattern electroretinogram in patients with early open-angle glaucoma. Doc. Ophthalmol. 1988; 69: 315-22.
124. Watanabe I, Iijima H, Tsukahara S. The pattern electroretinogram in glaucoma: An evaluation by relative amplitude from the Bjerrum area. Br. J. Ophthalmol. 1989; 73: 131-5.
125. Van den Berg TJTP, Riemslag FCC, de Vos GWGA, Verduyn Lunel HFE. Pattern ERG and glaucomatous visual field defects. Doc. Ophthalmol. 1986; 61: 335-41.
126. Marx MS, Podos SM, Bodis-Wollner I et al. Flash and pattern electroretinograms in normal and laser-induced glaucomatous primate eyes. Invest. Ophthalmol. Vis. Sci. 1986; 27: 378-86.
127. Marx MS, Podos SM, Bodis-Wollner I et al. Signs of early damage in glaucomatous monkey eyes: Low spatial frequency losses in the pattern ERG and VEP. Exp. Eye Res. 1988; 46: 173-84.
128. Trick GL. Retinal potentials in patients with primary open-angle glaucoma. Physiological evidence for temporal frequency tuning defects. Invest. Ophthalmol. Vis. Sci. 1985; 16: 1750-8.
129. Holder GE. Abnormalities of the pattern ERG in optic nerve lesions: Changes specific for proximal retinal dysfunction. In: Barber C, Blum T, eds. Evoked potentials III. London: Butterworth, 1987; 221-4.
130. Trick GL. PRRP abnormalities in glaucoma and ocular hypertension. Invest. Ophthalmol. Vis. Sci. 1986; 27: 1730-6.
131. Ruben ST, Hitchings RA, Fitzke F, Arden GB. Electrophysiology and psychophysics in ocular hypertension and glaucoma: Evidence for different pathomechanisms in early glaucoma. Eye 1994; 8: 516-20.
132. Porciatti V, Falsini B, Brunori S et al. Pattern electroretinograms as a function of spatial frequency in ocular hypertension and early glaucoma. Doc. Ophthalmol. 1987; 65: 349-55.
133. Nesher R, Trick GL. The pattern electroretinogram in retinal and optic nerve disease: A quantitative comparison of the pattern of visual dysfunction. Doc Ophthalmol. 1991; 77: 225-35.
134. Ambrosio G, Arienzo G, Aurilla P et al. Pattern electroretinograms in ocular hypertension. Doc. Ophthalmol. 1988; 69: 161-5.
135. Wanger P, Persson HE. Pattern-reversal electroretinograms in ocular hypertension. Doc Ophthalmol. 1985; 29: 1486-91.
136. Trick GL, Nesher RN, Cooper D et al. Dissociation of visual deficits in ocular hypertension. Invest. Ophthalmol. Vis. Sci. 1988; 29: 1486-91.
137. Trick CL. Visual impairments in a glaucoma and ocular hypertension (OHT): Results of a 4-year prospective study. Invest. Ophthalmol. Vis. Sci. 1991; 32 (Suppl.): 1192.
138. Trick G. Pattern electroretinogram: An electrophysiological technique applicable to primary open-angle glaucoma and ocular hypertension. J. Glaucoma 1992; 1: 271-9.
139. Neoh C, Kaye SB, Brown M, Ansons AM, Wishart P. Pattern electroretinogram and automated perimetry in patients with glaucoma and ocular hypertension. Br. J. Ophthalmol. 1994; 78: 359-62.
140. Trick GL. The pattern electroretinogram in glaucoma and ocular hypertension. In: Heckenlively JB, Arcon GB, eds. Principles and practice of clinical electrophysiology of vision. St Louis: Mosby, 1991; 766-72.
141. Siliprandi R, Bucci MG, Canella R, Cormignoto G. Flash and pattern electroretinograms during and after acute intraocular pressure elevation in cats. Invest. Ophthalmol. Vis. Sci. 1988; 29: 558-65.
142. Trick GL, Bickler-Bluth M, Cooper DG et al. Pattern reversal electroretinogram (PRERG) abnormalities in ocular hypertension: Correlation with glaucoma risk factors. Curr. Eye Res. 1988; 7: 201-6.
143. Graham SL, Wong VA, Drance SM, Mikelberg FS. Pattern electroretinograms from hemifields in normal and glaucoma patients. Invest. Ophthalmol. Vis. Sci. 1994; 35: 3347-56.
144. Holopigian K, Snow J, Seiple W, Siegel I. Variability of the pattern electroretinogram. Doc. Ophthalmol. 1988; 70: 103-15.
145. Birch DG, Anderson JL, Fish GE, Jost BF. Pattern-reversal electroretinographic acuity in untreated eyes with subfoveal neovascular membranes. Invest. Ophthalmol. 1992; 33: 2097-104.
146. Trick GL. Retinal and cortical evoked potentials in diabetics with minimal retinopathy. Clin. Vis. Sci. 1991; 6: 209-18.
147. Berninger T, Schuurmans RP. Spatial tuning of the pattern ERG across temporal frequency. Doc. Ophthalmol. 1985; 61: 17-25.
148. Sutter EE, Tran D. The field topography of ERC components in man 1. The photopic luminance response. Vis. Res. 1992; 32: 433-46.
149. Victor JD. Nonlinear systems analysis in vision. Overview of kernel methods. In: Pinter RB, Nabet B eds. Nonlinear vision: Determination of neural receptive fields, functions and networks. Cleveland: CRC Press, 1992; 1-37.
150. Sutter EE. A deterministic approach to non-linear systems analysis. In: Pinter RB, Nabet B eds. Nonlinear vision. Determination of neural receptive fields, functions and networks. Cleveland: CRC Press, 1992; 171-220.
151. Baseler HA, Sutter EE, Klein SA, Carney T. The topography of visual evoked response properties across the visual field. Electroencephalogr. Clin. Neurophysiol. 1994; 90: 65-81.
152. Vaegan, Buckland L. The spatial distribution of ERG losses across the posterior pole of glaucomatous eyes in multifocal recordings. Aust. N.Z. J. Ophthalmol. 1996; 24 (Suppl.): 28-31.
153. Klistorner A. Temporal non-linear analysis of human retinal and cortical visual evoked potentials: Relation to parallel processing. PhD Thesis, University of NSW, Sydney, NSW, Australia. 1997.
154. Hetherington APB, Arden GB, Wolf JE. Comparison of perimeter testing and multifocal ERGs in glaucoma. Invest. Ophthalmol. Vis. Sci. 1997; 38 (Suppl.): S568.
155. Klistorner A, Crewther DP, Crewther SG. Temporal analysis of the VEP: Evidence for separable magnocellular and parvocellular contributions. Aust. N.Z. J. Ophthalmol. 1996; 24 (Suppl.): 32-4.
156. Lee BB, Pokorny J, Smith VC, Martin PR, Valberg A. Luminance and chromatic modulation sensitivity of macaque ganglion cells and human observers. J. Optom. Soc. Am. 1990; 7: 2223-36.
157. Quigley HA, Sanchez RM, Dunkelburger GR, Henaut NL, Baginski TA. Chronic glaucoma selectively damages large optic nerve fibers. Invest. Ophthalmol. Vis. Sci. 1987; 28: 913-18.
158. Glovinsky Y, Quigley HA, Dunkelberger GR. Retinal ganglion cell loss is size dependent in experimental glaucoma. Invest. Ophthalmol. Vis. Sci. 1991; 32: 484-91.
159. Graham SL. Selective nerve fibre loss in glaucoma: Magnocellular or parvocellular. Aust. N.Z. J. Ophthalmol. 1997; 25: 189-91 (Editorial).