Training intensity-dependent and tissue-specific increases in lactate uptake and MCT-1 in heart and muscle

Journal of Applied Physiology

Volumn 84, Issue 3, 1998, Pages 987-994

  Baker, Steven K ^a   Mccullagh, Karl J A ^a   Bonen, Arend ^a  

^a UNIVERSITY OF WATERLOO   (Canada)

Author keywords

Citrate synthase; Extensor digitorum longus; Red gastrocnemius; Soleus; White gastrocnemius

Indexed keywords

CARBOXYLIC ACID DERIVATIVE; LACTIC ACID;

AEROBIC METABOLISM; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; EXTENSOR DIGITORUM LONGUS MUSCLE; GASTROCNEMIUS MUSCLE; HEART MUSCLE METABOLISM; HUMAN TISSUE; MUSCLE METABOLISM; NONHUMAN; PRIORITY JOURNAL; SOLEUS MUSCLE; TRAINING; TREADMILL;

EID: 0031913233     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.1998.84.3.987     Document Type: Article

References (40)

1. Bonen, A., and D. Homonko. Effects of exercise and glycogen depletion on glyconeogenesis in muscle. J. Appl. Physiol. 76: 1753-1758, 1994.
2. Bonen, A., and K. J. A. McCullagh. Effects of exercise on lactate transport into mouse skeletal muscles. Can. J. Appl. Physiol. 19: 275-285, 1994.
3. Bonen, A., J. C. McDermott, and M. H. Tan. Glycogenesis and glyconeogenesis in skeletal muscle: effects of pH and hormones. Am. J. Physiol. 258 (Endocrinol. Metab. 21): E693-E700, 1990.
4. Carpenter, L., R. C. Poole, and A. P. Halestrap. Cloning and sequencing of the monocarboxylate transporter from mouse Ehrlich-Lettre tumour cells confirms its identity as MCT-1 and demonstrates that glycosylation is not required for MCT-1 function. Biochim. Biophys. Acta 1279: 157-163, 1996.
5. Chi, M. M.-Y., C. S. Hintz, E. F. Coyle, W. H. Martin, J. L. Ivy, P. M. Nemeth, J. O. Holloszy, and O. H. Lowry. Effects of detraining on enzymes of energy metabolism in individual human muscle fibers. Am. J. Physiol. 244 (Cell Physiol. 13): C276-C287, 1983.
6. Dubouchaud, H., P. Granier, J. Mercier, C. Le Peuch, and C. Prefaut. Lacate uptake by skeletal muscle sarcolemmal vesicles decreases after 4 wk of hindlimb unweighting in rats. J. Appl. Physiol. 80: 416-421, 1996.
7. Ferdinandy, P., M. Koltai, A. Tosaki, P. Berthet, T. Tarrade, A. Esanu, and P. Braquet. Cicletanine improves myocardial function deteriorated by ischemia/reperfusion in isolated working hearts. J. Cardiovasc. Pharmacol. 19: 181-189, 1992.
8. Garcia, C. K., M. S. Brown, R. K. Pathak, and J. L. Goldstein. cDNA cloning of MCT-2, a second monocarboxylate transporter expressed in different cells than MCT-1. J. Biol. Chem. 270: 1843-1849, 1995.
9. Garcia, C. K., J. L. Goldstein, R. K. Pathak, G. W. Anderson, and M. S. Brown. Molecular characterization of a membrane transporter for lactate, pyruvate, and other monocarboxylates: implications for the Cori cycle. Cell 76: 865-873, 1994.
10. Henriksen, E. J., and A. E. Halseth. Early alterations in soleus GLUT-4, glucose transport, and glycogen in voluntary running rats. J. Appl. Physiol. 76: 1862-1867, 1994.
11. Johannsson, E., K. J. A. McCullagh, X.-X. Han, P. K. Fernando, J. Jensen, H. A. Dahl, and A. Bonen. Effect of overexpressing GLUT-1 and GLUT-4 on insulin- and contraction-stimulated glucose transport in muscle. Am. J. Physiol. 271 (Endocrinol. Metab.) 34: E547-E555, 1996.
12. Johannsson, E., E. A. Nagelhus, K. J. A. McCullagh, O. M. Sejersted, T. W. Blackstad, A. Bonen, and O.-P. Otterson. Cellular and subcellular expression of the monocarboxylate transporter MCT-1 in rat heart. A high resolution immunogold analysis. Circ. Res. 400-407, 1997.
13. Juel, C. Symmetry and pH dependency of the lactate/proton carrier in skeletal muscle studied with rat sarcolemmal giant vesicles. Biochim. Biophys. Acta 1283: 106-110, 1996.
14. Juel, C., A. Honig, and H. Pilegaard. Muscle lactate transport studied in sarcolemmal giant vesicles: dependence on fiber type and age. Acta Physiol. Scand. 143: 361-365, 1991.
15. Juel, C., and F. Wibrand. Lactate transport in isolated mouse muscles studied with a tracer technique - kinetics, stereospecificity, pH dependency and maximal capacity. Acta Physiol. Scand. 137: 33-39, 1989.
16. Mann, G. E. B., B. V. Zlokovic, and D. L. Yudilevich. Evidence for lactate transport system in the sarcolemmal membrane of the perfused rabbit heart: kinetics of unidirectional influx, carrier, specificity and effects of glucagon. Biochim. Biophys. Acta 19: 241-248, 1985.
17. McCullagh, K. J. A., and A. Bonen. Reduced lactate transport in denervated rat skeletal muscle. Am. J. Physiol. 269 (Regulatory Integrative Comp. Physiol. 38): R884-R888, 1995.
18. McCullagh, K. J. A., C. Juel, M. O'Brien, and A. Bonen. Chronic muscle stimulation increases lactate transport in rat skeletal muscle. Mol. Cell. Biochem. 156: 51-57, 1996.
19. McCullagh, K. J. A., R. C. Poole, A. P. Halestrap, M. O'Brien, and A. Bonen. Chronic electrical stimulation increases MCT-1 and lactate uptake in red and white skeletal muscle. Am. J. Physiol. 273 (Endocrinol. Metab. 36): E239-E246, 1997.
20. McCullagh, K. J. A., R. C. Poole, A. P. Halestrap, M. O'Brien, and A. Bonen. Role of the lactate transporter (MCT-1) in skeletal muscles. Am. J. Physiol. 271 (Endocrinol. Metab. 34): E143-E150, 1996.
21. McDermott, J. C., and A. Bonen. Endurance training increases skeletal muscle lactate transport. Acta Physiol. Scand. 147: 323-327, 1993.
22. McDermott, J. C., and A. Bonen. Lactate transport by skeletal muscle sarcolemmal vesicles. Mol. Cell. Biochem. 122: 113-121, 1993.
23. McDermott, J. C., and A. Bonen. Lactate transport in rat sarcolemmal vesicles and intact skeletal muscle, and after muscle contraction. Acta Physiol. Scand. 151: 17-28, 1994.
24. Phillips, S., X.-X. Han, H. J. Green, and A. Bonen. Increments in skeletal muscle GLUT-1 and GLUT-4 after endurance training in humans. Am. J. Physiol. 270 (Endocrinol. Metab. 33): E456-E462, 1996.
25. Pilegaard, H., C. Juel, and F. Wibrand. Lactate transport studied in sarcolemmal giant vesicles from rats: effects of training. Am. J. Physiol. 264 (Endocrinol. Metab. 27): E156-E160, 1993.
26. Poole, R. C., S. L. Cranmer, A. P. Halestrap, and A. J. Levi. Substrate and inhibitor specificity of monocarboxyolate transport into heart cells and erythrocytes. Biochem. J. 269: 827-829, 1990.
27. Powers, S. K., D. Criswell, J. Lawler, D. Martin, F. K. Liue, L. L. Ji, and R. A. Herb. Rigorous exercise training increases superoxide dismutase activity in ventricular myocardium. Am. J. Physiol. 265 (Heart Circ. Physiol. 34): H2094-H2098, 1993.
28. Ren, J. M., C. F. Semenkovich, E. A. Gulve, J. Gao, and J. O. Holloszy. Exercise induces rapid increases in GLUT-4 expression, glucose transport capacity, and insulin-stimulated glycogen storage in muscle. J. Biol. Chem. 269: 14396-14401, 1994.
29. Roth, D. A., and G. A. Brooks. Lactate and pyruvate transport is dominated by a pH gradient-sensitive carrier in rat skeletal muscle sarcolemmal vesicles. Arch. Biochem. Biophys. 279: 386-394, 1990.
30. Roth, D. A., and G. A. Brooks. Lactate transport is mediated by a membrane-bound carrier in rat skeletal muscle sarcolemmal membranes. Arch. Biochem. Biophys. 279: 377-385, 1990.
31. Takanaga, H., I. Tamai, S. Inaba, Y. Sai, H. Higashida, H. Yamamoto, and A. Tsuji. cDNA cloning and functional characterization of rat intestinal monocarboxylate transporter. Biochem. Biophys. Res. Commun. 217: 370-377, 1995.
32. Tamai, I., H. Takanaga, H. Maeda, Y. Sai, T. Ogihara, H. Higashida, and A. Tsuji. Participation of a proton-cotransporter, MCT-1, in the intestinal transport of monocarboxylic acids. Biochem. Biophys. Res. Commun. 214: 482-489, 1995.
33. Tidiius, P. M., and M. E. Houston. Antioxidant and oxidative enzyme adaptations to vitamin E deprivation and training. Med. Sci. Sports Exerc. 26: 354-359, 1994.
34. Trosper, T. L., and K. D. Philipson. Functional characteristics of the cardiac sarcolemmal monocarboxylate transporter. J. Membrane Biol. 112: 15-23, 1989.
35. Trosper, T. L., and K. D. Philipson. Lactate transport by cardiac sarcolemmal vesicles. Am. J. Physiol. 252 (Cell Physiol. 21): C483-C489, 1987.
36. i recovery after global ischemia in the perfused heart. Circ. Res. 72: 993-1003, 1993.
37. i. Am. J. Physiol. 267 (Heart Circ. Physiol. 36): H1759-H1769, 1994.
38. Wang, X., A. J. Levi, and A. P. Halestrap. Substrate and inhibitor specificities of the monocarboxylate transporters of single rat heart cells. Am. J. Physiol. 270 (Heart Circ. Physiol. 39): H476-H484, 1996.
39. Wang, X., R. C. Poole, A. P. Halestrap, and A. J. Levi. Characterization of the inhibition by stilbene disulphonates and phloretin of lactate and pyruvate transport into rat and guinea-pig cardiac myocytes suggests the presence of two kinetically distinct carriers in heart cells. Biochem. J. 290: 249-258, 1993.
40. Watt, P. W., P. A. MacLennan, H. S. Hundal, C. M. Kuret, and M. J. Rennie. L(+)-Lactate transport in perfused rat skeletal muscle: kinetic characteristics and sensitivity to pH and transport inhibitors. Biochim. Biophys. Acta 944: 213-222, 1988.