Validation of an improved reversed-phase high-performance liquid chromatography assay with reductive electrochemical detection for the determination of artemisinin derivatives in man

Therapeutic Drug Monitoring

Volumn 20, Issue 1, 1998, Pages 109-116

  Van Agtmael, Michiel A ^a   Butter, Jan J ^a   Portier, Els J G ^a   Van Boxtel, Chris J ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Artemether; Artemisinin derivative; Assay; Dihydroartemism; Electrochemical detection; High performance liquid chromatography; Validation

Indexed keywords

ARTEMETHER; ARTEMISIN DERIVATIVE; DIHYDROARTEMISININ;

ACCURACY; ARTICLE; DRUG DETERMINATION; ELECTROCHEMICAL DETECTION; HUMAN; INTERMETHOD COMPARISON; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; REPRODUCIBILITY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ANTIMALARIALS; ARTEMISININS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ELECTROCHEMISTRY; HUMANS; SESQUITERPENES;

EID: 0031911636     PISSN: 01634356     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007691-199802000-00020     Document Type: Article

References (17)

1. White NJ. Artemisinin: current status. Transactions of the Royal Society of Tropical Medicine & Hygiene 1994;88(suppl 1):S3-S4.
2. Hien TT. An overview of the clinical use of artemisinin and its derivatives in the treatment of falciparum malaria in Viet Nam. [Review]. Transactions of the Royal Society of Tropical Medicine & Hygiene 1994;88(suppl 1):S7-S8.
3. Zhou ZM, Anders JC, Chung H, Theoharides AD. Analysis of artesunic acid and dihydroqinghaosu in blood by high-performance liquid chromatography with reductive electrochemical detection. J Chromatogr 1987;414:77-90.
4. van Boxtel CJ, van Agtmael MA, de Vries PJ, Tran Khac Dien, Koopmans R-P, Kager PA. Some pharmacokinetic and dynamic comparisons of artemisinin derivatives in man. Jpn J Trop Med Hyg 1996;24:49-54.
5. Melendez V, Peggins JO, Brewer TG, Theoharides AD. Determination of the antimalarial arteether and its deethylated metabolite dihydroartemisinin in plasma by high-performance liquid chromatography with reductive electrochemical detection. J Pharm Sci 1991;80:132-8.
6. Edwards G. Measurement of artemisinin and its derivatives in biological fluids. Transactions of the Royasl Society of Tropical Medicine and Hygiene 1994;88(suppl 1):37-39.
7. Mount DL Todd GD, Navaratnam V. Packed-column supercritical fluid chromatography of artemisinin (qinghaosu) with electron-capture detection. J Chromatogr B Biomed Appl 1995;666:183-7.
8. Green MD, Mount DL, Todd GD, Capomacchia AC. Chemiluminescent detection os artemisinin-novel endoperoxide analysis usine luminol without hydrogen peroxide. J Chromatogr 1995;695: 237-42.
9. Sandrenan N, Sioufi A, Godbillon J, Netter C, Donker M, van Valkenburg C. Determination of artemether and its metabolite, dihydroartemisinin, in plasma by high-performance liquid chromatography and electro-chemical detection in the reductive mode. J Chromatogr B 1997;691:145-53.
10. Navaratnam V, Mansor SM, Chin LK, Mordi MN, Asokan M, Nair NK Determination of artemether and dihydroartemisinin in blood plasma by high-performance liquid chromatography for application in clinical pharmacological studies. J Chromatogr B Biomed Appl 1995;669:289-94.
11. White NJ. Clinical pharmacokinetics and pharmacodynamics of artemisinin and derivatives. Transactions of the Royal Society of Tropical Medicine & Hygiene 1994;88(suppl 1):S41-3.
12. Looareesuwan S. Overview of clinical studies on artemisinin derivatives in Thailand. [review]. Transactions of the Royal Society of Tropical Medicine & Hygiene 1994;88(suppl 1):S9-11.
13. de Vries PJ, Tran KD. Clinical pharmacology and therapeutic potential of artemisinin and its derivatives in the treatment of malaria. Drugs 1996;52:818-36.
14. Edwards G, Winstanley PA, Ward SA. Clinical pharmacokinetics in the treatment of tropical diseases: Some applications and limitations. [review]. Clin Pharmacokinet 1994;27:150-65.
15. Duc DD, de Vries PJ, Nguyen XK, Le Nguyen B, Kager PA, van Boxtel CJ. The pharmacokinetics of a single dose of artemisinin in healthy Vietnamese subjects. Am J Trop Med Hyg 1994;51:785-90.
16. Kager PA, Schultz MJ, Zijlstra EE, van den Berg B, van Boxtel CJ. Arteether administration in humans: preliminary studies of pharmacokinetics, safety and tolerance. Transactions of the Royal Society of Tropical Medicine & Hygiene 1994;88(suppl 1):S53-4.
17. van Boxtel CJ, de Vries PJ, Tran KD, Koopmans RP, Kager PA. Pharmacokinetics of artemisinin and derivatives. Proceedings of the 7th Southeast Asian/Western Pacific Regional Meeting of Pharmacologists "Towards Rational Drug Therapy at the Turn of the Century." November 1995, Manila, Philippines 1996;498-504.