Serotonin stimulates corticotropin-releasing factor gene expression in the hypothalamic paraventricular nucleus of conscious rats

Neuroscience Letters

Volumn 243, Issue 1-3, 1998, Pages 17-20

  Kageyama, Kazunori ^a   Tozawa, Fumiko ^a   Horiba, Nobuo ^a   Watanobe, Hajime ^a   Suda, Toshihiro ^a  

^a HIROSAKI UNIVERSITY   (Japan)

Author keywords

Adrenocorticotropic hormone; Corticotropin releasing factor mRNA; In vivo; Microinjection; Proopiomelanocortin; Serotonin

Indexed keywords

1 ISOPROPYL 6 METHYLERGOLINE 8 CARBOXYLIC ACID 2 HYDROXY 1 METHYLPROPYL ESTER; 1 METHYL 3 INDAZOLECARBOXYLIC ACID N TROPANYLAMIDE; CORTICOTROPIN; CORTICOTROPIN RELEASING FACTOR; MESSENGER RNA; PROOPIOMELANOCORTIN; SEROTONIN; SEROTONIN 1A RECEPTOR; SEROTONIN 3 RECEPTOR;

ADOLESCENT; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; GENE INDUCTION; HORMONE RELEASE; HORMONE SYNTHESIS; MALE; MICROINJECTION; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; RAT; THALAMUS MIDLINE NUCLEUS;

ADRENOCORTICOTROPIC HORMONE; ANIMALS; BLOTTING, NORTHERN; CONSCIOUSNESS; CORTICOTROPIN-RELEASING HORMONE; DOSE-RESPONSE RELATIONSHIP, DRUG; ERGOLINES; GENE EXPRESSION; MALE; MICROINJECTIONS; NEURONS; PARAVENTRICULAR HYPOTHALAMIC NUCLEUS; PINDOLOL; PRO-OPIOMELANOCORTIN; RATS; RATS, WISTAR; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; RNA, MESSENGER; SEROTONIN; SEROTONIN ANTAGONISTS;

EID: 0031911558     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(98)00097-4     Document Type: Article

References (14)

1. Antoni F.A. Hypothalamic control of adrenocorticotropin secretion: advances since the discovery of 41-residue corticotropin-releasing factor. Endocr. Rev. 7:1986;351-378.
2. Calogero A.E., Bagdy G., Szemerdi K., Tartaglia M.E., Gold P.W., Chrousos G.P. Mechanism of serotonin receptor agonist-induced activation of the hypothalamic-pituitary adrenal axis in the rat. Endocrinology. 126:1990;1888-1894.
3. 3 receptor. J. Med. Chem. 30:1987;1535-1537.
4. Gibbs D.M., Vale W. Effect of the serotonin reuptake inhibitor fluoxetine on corticotropin-releasing factor and vasopressin secretion into hypophysial portal blood. Brain Res. 280:1983;176-179.
5. Itoi K., Suda T., Tozawa F., Dobashi I., Ohmori N., Sakai Y., Abe K., Demura H. Microinjection of norepinephrine into the paraventricular nucleus of the hypothalamus stimulates corticotropin-releasing factor gene expression in conscious rats. Endocrinology. 135:1994;2177-2182.
6. Itoi K., Horiba N., Tozawa F., Sakai Y., Sakai K., Abe K., Demura H., Suda T. Major role of 3′, 5′-cyclic adenosine monophosphate-dependent protein kinase A pathway in corticotropin-releasing factor gene expression in the rat hypothalamus in vitro. Endocrinology. 137:1996;2389-2396.
7. 1A receptor-mediated regulation of plasma neuroendocrine hormones. J. Pharmacol. Exp. Ther. 271:1994;1246-1252.
8. Negro-Vilar A., Johnston C., Spinedi E., Valen M., Lopez F. Physiological role of peptides and amines on the regulation of ACTH secretion. Ann. N. Y. Acad. Sci. 512:1987;218-236.
9. Ohmori N., Itoi K., Tozawa F., Sakai Y., Sakai K., Horiba N., Demura H., Suda T. Effect of acetylcholine on corticotropin-releasing factor gene expression in the hypothalamic paraventricular nucleus of conscious rats. Endocrinology. 136:1994;4858-4863.
10. 1A receptor subtype in the paraventricular nuclei of the hypothalamus induces CRH and ACTH release in the rat. Neuroendocrinology. 56:1992;797-802.
11. 3 receptors. J. Med. Chem. 33:1990;3176-3181.
12. Suda T. Corticotropin-releasing factor gene expression. Methods Neurosci. 9:1992;23-31.
13. Suda T., Nakano Y., Tozawa F., Sumitomo T., Sato Y., Yamada M., Demura H. The role of corticotropin-releasing factor and vasopressin in hypoglycemia-induced proopiomelanocortin gene expression in the rat anterior pituitary gland. Brain Res. 579:1992;303-308.
14. 2 agonist, (±)-1-(2, 5-dimethoxy-4-iodophenyl)-2-aminopropane. J. Pharmacol. Exp. Ther. 270:1994;918-928.