Increased apolipoprotein E mRNA in the hippocampus in Alzheimer disease and in rats after entorhinal cortex lesioning

Experimental Neurology

Volumn 149, Issue 1, 1998, Pages 79-86

  Zarow, Chris ^a   Victoroff, Jeff ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Alzheimer disease; Apolipoprotein E; Astrocytes; Entorhinal cortex lesion

Indexed keywords

APOLIPOPROTEIN E;

AGED; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN CORTEX LESION; CLINICAL ARTICLE; CONTROLLED STUDY; ENTORHINAL CORTEX; FEMALE; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; MALE; NEUROPIL; NONHUMAN; PERIKARYON; PRIORITY JOURNAL; RAT;

EID: 0031911126     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1006/exnr.1997.6709     Document Type: Article

References (55)

1. Angerer L. M., Cox K. H., Angerer R. C. Demonstration of tissue-specific gene expression by in situ hybridization. Methods Enzymol. 152:1987;649-661.
2. Basheeruddin K., Rechtoris C., Mazzone T. Transcriptional and post-transcriptional control of apolipoprotein E gene expression in differentiating human monocytes. J. Biol. Chem. 267:1992;1219-1224.
3. Bertrand P., Poirier J., Oda T., Finch C. E., Pasinetti G. M. Association of apolipoprotein E genotype with brain levels of apolipoprotein E and apolipoprotein J (clusterin) in Alzheimer's disease. Mol. Brain Res. 33:1995;174-178.
4. Betard C., Robitaille Y., Gee M., Tiberghien D., Larrivee D., Roy P., Mortimer J. A., Gauvreau D. Apo E allele frequencies in Alzheimer's disease, Lewy body dementia, Alzheimer's disease with cerebrovascular disease and vascular dementia. NeuroReport. 5:1994;1893-1896.
5. Boyles J. K., Notterpek L. M., Anderson L. J. Accumulation of apolipoproteins in the regenerating and remyelinating mammalian peripheral nerve. Identification of apolipoprotein D, apolipoprotein A-IV, apolipoprotein E, and apolipoprotein A-I. J. Biol. Chem. 265:1990;17805-17815.
6. Boyles J. K., Pitas R. E., Wilson E., Mahley R. W., Taylor J. M. Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system. J. Clin. Invest. 76:1985;1501-1513.
7. Boyles J. K., Zoellner C. D., Anderson L. J., Kosik L. M., Pitas R. E., Weisgraber K. H., Hui D. Y., Mahley R. W., Gebicke-Haerter P. J., Ignatius M. J. A role for apolipoprotein E, apolipoprotein A-I, and low density lipoprotein receptors in cholesterol transport during regeneration and remyelination of the rat sciatic nerve. J. Clin. Invest. 83:1989;1015-1031.
8. Caceres A., Busciglio J., Ferreira A., Steward O. An immunocytochemical and biochemical study of the microtubule-associated protein MAP-2 during post-lesion dendritic remodeling in the central nervous system of adult rats. Brain Res. 1988;233-246.
9. Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:1987;156-159.
10. Corder E. H., Saunders A. M., Strittmatter W. J., Schmechel D. E., Gaskell P. C., Small G. W., Roses A. D., Haines J. L., Pericak-Vance M. A. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science. 261:1993;921-923.
11. Couderc R., Mahieux F., Bailleul S., Fenelon G., Mary R., Fermanian J. Prevalence of apolipoprotein E phenotypes in ischemic cerebrovascular disease. A case-control study. Stroke. 24:1993;661-664.
12. Davignon J., Gregg J. E., Sing C. F. Apolipoprotein E polymorphism and atherosclerosis. Arteriosclerosis. 8:1988;1-21.
13. Day J. R., Min B. H., Laping N. J., Martin G., Osterburg H. H., Finch C. E. New mRNA probes for hippocampal responses to entorhinal cortex lesions in the adult male rat: A preliminary report. Exp. Neurol. 117:1992;97-99.
14. Diedrich J. F., Minnigan H., Carp R. I., Whitaker J. N., Race R., Frey W., Haase A. T. Neuropathological changes in scrapie and Alzheimer's disease are associated with increased expression of apolipoprotein E and cathepsin D in astrocytes. J. Virol. 65:1991;4759-4768.
15. Dory L. Regulation of apolipoprotein E secretion by high density lipoprotein 3 in mouse macrophages. J. Lipid Res. 32:1991;783-792.
16. Eichner J. E., Ferrell R. E., Kamboh M. I., Kuller L. H., Becker D. J., Drash A. L., Stein E. A., Orchard T. J. The impact of the apolipoprotein E polymorphism on the lipoprotein profile in insulin-dependent diabetes: The Pittsburgh Epidemiology of Diabetes Complications Study IX. Metabolism. 41:1992;347-351.
17. Elshourbagy N. A., Liao W. S., Mahley R. W., Taylor J. M. Apolipoprotein E mRNA is abundant in the brain and adrenals, as well as in the liver, and is present in other peripheral tissues of rats and marmosets. Proc. Natl. Acad. Sci. USA. 87:1985;203-207.
18. Feussner G., Wey S., Bommer J., Deppermann D., Grützmacher P., Ziegler R. Apolipoprotein E phenotypes and hyperlipidemia in patients under maintenance hemodialysis. Hum. Genet. 88:1992;307-312.
19. Gage F. H., Olejniczak P., Armstrong D. M. Astrocytes are important for sprouting in the septohippocampal circuit. Exp. Neurol. 102:1988;2-13.
20. Gao W., Hatten M. E. Neuronal differentiation rescued by implantation of weaver granule cell precursors into wild-type cerebellar cortex. Science. 260:1993;367-369.
21. Geddes J. W., Hess E. J., Hart R. A., Kesslak J. P., Cotman C. W., Wilson M. C. Lesions of hippocampal circuitry define synaptosomal-associated protein-25 (SNAP-25) as a novel presynaptic marker. Neuroscience. 38:1990;515-525.
22. Geddes J. W., Monaghan D. T., Cotman C. W., Lott I. T., Kim R. C., Chui H. C. Plasticity of hippocampal circuitry in Alzheimer's disease. Science. 230:1985;1179-1181.
23. Geddes J. W., Wilson M. C., Miller F. D., Cotman C. W. Molecular markers of reactive plasticity. Adv. Exp. Med. Biol. 268:1990;425-432.
24. Goodrum J. F. Cholesterol from degenerating nerve myelin becomes associated with lipoproteins containing apolipoprotein E. J. Neurochem. 56:1991;2082-2086.
25. Hyman B. T., Van Hoesen G. W., Damasio A. R., Barnes C. L. Alzheimer's disease: Cell-specific pathology isolates the hippocampal formation. Science. 225:1984;1168-1170.
26. Ignatius M. J., Gebicke-Haerter P. J., Pitas R. E., Shooter E. M. Apolipoprotein E in nerve injury and repair. Prog. Brain Res. 71:1987;177-183.
27. Ignatius M. J., Gebieke-Harter P. J., Skene J. H. P., Schilling J. W., Weisgraber K. H., Mahley R. W., Shooter E. M. Expression of apolipoprotein E during nerve degeneration and regeneration. Proc. Natl. Acad. Sci. 83:1986;1125-1229.
28. Kosaka T., Hama K. Three-dimensional structure of astrocytes in the rat dentate gyrus. J. Comp. Neurol. 249:1986;242-260.
29. Lee J. J., Costlow N. A. A molecular titration assay to measure transcript prevalence levels. Methods Enzymol. 152:1987;633-648.
30. Mahley R. W. Apolipoprotein E: Cholesterol transport protein with an expanding role in cell biology. Science. 240:1988;622-629.
31. Metzger R. E., Falduto M. T., Pan J. B., Frail D. E., Ladu M. J., Getz G. S., Mufson E. Human cerebral cortical neurons display apolipoprotein E immunoreactivity. Soc. Neurosci. Abstracts. 20:1994;1032.
32. Müller H. W., Gebicke-Härter P. J., Hangen D. H., Shooter E. M. A specific 37,000-dalton protein that accumulates in regenerating but not in nonregenerating mammalian nerves. Science. 228:1985;499-501.
33. Nakai M., Kawamata T., Taniguchi T., Maeda K., Tanaka C. Expression of apolipoprotein E mRNA in rat microglia. Neurosci. Lett. 211:1996;41-44.
34. Namba Y., Tomonaga M., Kawasaki H., Otomo E., Ikeda K. Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease. Brain Res. 541:1991;163-166.
35. Namba Y., Tsuchiya H., Ikeda K. Apolipoprotein B immunoreactivity in senile plaque and vascular amyloids and neurofibrillary tangles in the brains of patients with Alzheimer's disease. Neurosci. Lett. 134:1992;264-266.
36. Noguchi S., Murakami K., Yamada N. Apolipoprotein E genotype and Alzheimer's disease. Lancet. 342:1993;737.
37. Pedro-Botet J., Senti M., Noguës X., Rubiës-Prat J., Roquer J., D'Olhaberriague L., Olivë J. Lipoprotein and apolipoprotein profile in men with ischemic stroke. Role of lipoprotein(a), triglyceride-rich lipoproteins, and apolipoprotein E polymorphism. Stroke. 23:1992;1556-1562.
38. Pitas R. E., Boyles J. K., Lee S. H., Foss D., Mahley R. W. Astrocytes synthesize apolipoprotein E and metabolize apolipoprotein E-containing lipoproteins. Biochem. Biophys. Res. Commun. 917:1987;148-161.
39. Poirier J., Davignon J., Bouthillier D., Kogan S., Bertrand P., Gauthier S. Apolipoprotein E polymorphism and Alzheimer's disease. Lancet. 342:1993;697-699.
40. Poirier J., Hess M., May P. C., Finch C. E. Cloning of hippocampal poly(A) RNA sequences that increase after entorhinal cortex lesion in adult rat. Mol. Brain Res. 9:1991;191-195.
41. Poirier J., Hess M., May P. C., Finch C. E. Astrocytic apolipoprotein E mRNA and GFAP mRNA in hippocampus after entorhinal cortex lesioning. Mol. Brain Res. 11:1991;97-106.
42. Rebeck G. W., Reiter J. S., Strickland D. K., Hyman B. T. Apolipoprotein E in sporadic Alzheimer's disease: Allelic variation and receptor interactions. Neuron. 11:1993;575-580.
43. Rose G., Lynch G., Cotman C. W. Hypertrophy and redistribution of astrocytes in the deafferented dentate gyrus. Brain Res. Bull. 1:1976;87-92.
44. Rouis M., Nigon F., Eggerman T. L., Brewer H. B. Jr., Chapman M. J. Apolipoprotein E expression by human-monocyte-derived macrophages - Modulation by opsonised zymosan and cholesterol. Eur. J. Biochem. 189:1990;447-453.
45. Salomon R. N., Underwood R., Doyle M. V., Wang A., Libby P. Increased apolipoprotein E and c-fms gene expression without elevated interleukin 1 or 6 mRNA levels indicates selective activation of macrophage functions in advanced human atheroma. Proc. Natl. Acad. Sci. USA. 89:1992;2814-2818.
46. Scheff S. W., Bernardo L. S., Cotman C. W. Decline in reactive fiber growth in the dentate gyrus of aged rats compared to young adult rats following entorhinal cortex removal. Brain Res. 199:1980;21-38.
47. Simmons D. M., Arriza J. L., Swanson L. W. A complete protocol for in situ hybridization of messenger RNAs in brain and other tissues with radiolabeled single-stranded RNA probes. J. Histochem. Cytochem. 12:1989;169-181.
48. Snipes G. J., McGuire C. B., Norden J. J., Freeman J. A. Nerve injury stimulates the secretion of apolipoprotein E by nonneuronal cells. Proc. Natl. Acad. Sci. USA. 83:1986;1130-1134.
49. Strittmatter W. J., Saunders A. M., Schmechel D., Pericak-Vance M., Enghild J., Salvesen G. S., Roses A. D. Apolipoprotein E: High-avidity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc. Natl. Acad. Sci. 90:1993;1977-1981.
50. Tukey J. W. Exploratory Data Analysis. 1977;Addison-Wesley, Reading.
51. Van Bockxmeer F. M., Mamotte C. D. Apolipoprotein epsilon 4 homozygosity in young men with coronary heart disease. Lancet. 340:1992;879-880.
52. Vijayan V. K., Geddes J. W., Anderson K. J., Chang-Chui H., Ellis W. G., Cotman C. W. Astrocyte hypertrophy in the Alzheimer's disease hippocampal formation. Exp. Neurol. 112:1991;72-78.
53. Wisniewski T., Frangione B. Apolipoprotein E: A pathological chaperone protein in patients with cerebral and systemic amyloid. Neurosci. Lett. 135:1992;235-238.
54. Wisniewski T., Golabek A., Matsubara E., Ghiso J., Frangione B. Apolipoprotein E: Binding to soluble Alzheimer's β-amyloid. Biochem. Biophys. Res. Commun. 192:1993;359-365.
55. Zarow C., Finch C. E. Rapid septal astrocytic response following entorhinal cortex lesion. Soc. Neurosci. Abstracts. 16:1990;658.