Morphogenesis of benign prostatic hyperplasia and prostate carcinoma;Morphogenese der benignen prostatahyperplasie und des Prostatakarzinoms

Pathologe

Volumn 19, Issue 1, 1998, Pages 12-20

  Bonkhoff, H ^a   Remberger, K ^a  

^a SAARLAND UNIVERSITY   (Germany)

Author keywords

Benign prostate hyperplasia; Morphogenesis; Prostate carcinoma; Stem cell modell

Indexed keywords

BASEMENT MEMBRANE; CANCER GRADING; CELL POPULATION; GENETIC STABILITY; HUMAN; MORPHOGENESIS; ONCOGENE; PATHOGENESIS; PROSTATE CARCINOMA; PROSTATE HYPERTROPHY; REVIEW; STEM CELL; TUMOR GROWTH;

CELL TRANSFORMATION, NEOPLASTIC; EPITHELIUM; HUMANS; MALE; NEOPLASM INVASIVENESS; NEOPLASMS, HORMONE-DEPENDENT; PRECANCEROUS CONDITIONS; PROSTATE; PROSTATIC HYPERPLASIA; PROSTATIC NEOPLASMS;

EID: 0031909922     PISSN: 01728113     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002920050250     Document Type: Review

References (31)

1. Mc Neal JE (1989) Normal histology of the prostate. Am J Surg Pathol 12:619-633
2. Dhom G (1991) Pathologie der Prostata. In Dörr W, Seifert G (Hrsg) Pathologie des männlichen Genitale, Bd 21. Spezielle pathologische Anatomie. Springer, Berlin Heidelberg New York, S 455-642
3. Ware JL (1994) Prostate cancer progession. Implications of histopathology. Am J Pathol 145:983-993
4. Bonkhoff H, Remberger K (1996) Differentiation pathways and histogenetic aspects of normal and abnormal prostatic growth: a stem cell model. Prostate 28:98-106
5. Bonkhoff H (1996) Role of the basal cells in premalignant changes of the human prostate: a stem cell concept for the development of prostate cancer. Eur Urol 30:201-205
6. Bonkhoff H, Stein U, Remberger K (1994) Multidirectional differentiation in the normal, hyperplastic and neoplastic human prostate. Simultaneous demonstration of cell specific epithelial markers. Hum Pathol 25:42-46
7. Bonkhoff H, Stein U, Remberger K (1994) The proliferative function of basal cells in the normal and hyperplastic human prostate. Prostate 24:224-118
8. Bonkhoff H, Stein U, Remberger K (1995) Endocrine-paracrine cell types in the prostate and prostatic adenocarcinoma are postmitotic cells. Hum Pathol 26:167-170
9. Bonkhoff H, Fixemer T, Remberger K (1997) Relation between Bcl-2, cell proliferation and the androgen receptor status in prostate tissue and precursors of prostate cancer. Prostate (in press)
10. Bonkhoff H, Remberger K (1993) Widespread distribution of nuclear androgen receptors in the basal layer of the normal and hyperplastic human prostate. Virchows Archiv [A] 422:35-38
11. Bonkhoff H, Stein U, Aumuller G, Remberger K (1996) Differential expression of 5 α-reductase isoenzymes in the human prostate and prostatic carcinoma. Prostate 29:261-267
12. Bostwick DG (1995) High grade prostatic intraepithelial neoplasia. The most likely precusor of prostate cancer. Cancer 75:1823-1836
13. Qian J, Jenkins RB, Bostwick DG (1996) Potential markers of aggressiveness in prostatic intraepithelial neoplasia detected by fluorescence in situ hybridisation. Eur Urol 30:177-184
14. Myers RB, Grizzle WE (1996) Biomarker expression in prostatic intraepithelia neoplasia. Eur Urol 30:153-166
15. Montironi R, Bostwick DG, Bonkhoff H, Cockett A, Helpap B, Troncoso P, Waters D (1996) Origins of prostate cancer. Cancer 78:362-365
16. Grignon DJ, Sakr WA (1996) Atypical adenomatous hyperplasia of the prostate: a critical review. Eur Urol 30:206-211
17. Bostwick DG (1997) Neoplasms of the prostate. In: Bostwick DG, Eble JN (eds) Urologic surgical pathology. Mosby-Year Book, St. Louis
18. Bonkhoff H, Stein U, Remberger K (1993) Differential expression of α-6 and α-2 very late antigen integrins in the normal, hyperplastic and neoplastic human prostate. Simultaneous demonstration of cell surface receptors and their extracellular ligands. Hum Pathol 24:243-248
19. Bonkhoff H, Wernert N, Dhom G, Remberger K (1991) Basement membranes in fetal, adult normal, hyperplastic and neoplastic human prostate. Virchows Archiv [A] 418:375-381
20. Bonkhoff H, Wernert N, Dhom G, Remberger K (1992) Distribution of basement membranes in primary and metastatic carcinomas of the prostate. Hum Pathol 23:934-939
21. Pföhler C, Remberger K, Bonkhoff H (1996) Expressionsanalyse von Laminin- und Typ IV Coltagen-codierenden Genen in der Prostata und im Prostatakarzinom. Verh Dtsch Ges Path 80:646
22. Nagle RB, Hao J, Knox JD, Dalkin BC, Clark V, Cress AE (1995) Expression of hemidesmosomal and extracellular matrix proteins by normal and malignant human prostate tissue. Am J Pathol 146:1498-1507
23. Di Sant'Agnese PA (1992) Neuroendocrine differentiation in carcinoma of the prostate: diagnostic, prognostic and therapeutic implications. Cancer 70:254-268
24. Weinstein MH, Partin AW, Veltri RW, Epstein JI (1996) Neuroendocrine differentiation in prostate cancer: enhanced prediction of progession after radical prostatectomy. Hum Pathol 27:683-687
25. Grignon D, Caplan R, Sakr W, Porter A, Dogen RLS, John M, Abrams R, Lawtom C (1995) Neuroendocrine (NE) differentiation as a prognostic indicator in locally advanced prostate cancer (PCa). Lab Invest 72:76A
26. Bonkhoff H, Wernert N, Dhom G, Remberger K (1991) Relation of endocrine-paracrine cells to cell proliferation in normal, hyperplastic and neoplastic human prostate. Prostate 18:91-98
27. Bonkhoff H, Stein U, Remberger K (1993) Androgen receptor status in endocrine paracrine cell types of the normal, hyperplastic and neoplastic human prostate. Virchows Archiv [A] 423:291-294
28. Gottlieb B, Trifiro M, Lumbroso R, Vasiliou DM, Pinsky L (1996) The androgen receptor gene mutations database. Nucl Acids Res 24:151-154
29. Trapman J, Brinkmann AO (1996) The androgen receptor in prostate cancer. Pathol Res Pract 192:752-760
30. Visakorpi T, Hyytinen E, Koivisto P, Tanner M, Keinänen R, Palmberg C, Palotie A, Jammela T, Isola J, Kallioniemi OP (1995) In vivo amplification of the androgen receptor gene and progression of human prostate cancer. Nature Genet 9:401-406
31. Bonkhoff H (1997) Neuroendocrine cells in benign and malignant prostate tissue. Morphogenesis, proliferation and androgen receptor status. Prostate (in press)