Gene expression of luteinizing hormone receptor and steroidogenic enzymes during Leydig cell development

Journal of Molecular Endocrinology

Volumn 20, Issue 1, 1998, Pages 119-127

  Abney, T O ^a   Zhai, J ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); LUTEINIZING HORMONE RECEPTOR; STEROID 17ALPHA MONOOXYGENASE;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL REGENERATION; CONTROLLED STUDY; GENE EXPRESSION; LEYDIG CELL; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STEM CELL;

ANIMALS; BLOTTING, NORTHERN; CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME; CYTOCHROME P-450 ENZYME SYSTEM; LEYDIG CELLS; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, LH; RNA, MESSENGER; STEROID 17-ALPHA-HYDROXYLASE;

EID: 0031909220     PISSN: 09525041     EISSN: None     Source Type: Journal    
DOI: 10.1677/jme.0.0200119     Document Type: Article

References (37)

1. Bartke A, Hafiez AA, Bex FJ & Dalterio S 1978 Hormonal interactions in regulation of androgen secretion. Biology of Reproduction 18 44-54.
2. Bhalla VK, Abney TO & Mahesh VB 1993 Gonadotropin receptor gene expression in regenerating Leydig cells following a single in vivo injection of ethylene dimethylsufonate. Endocrine Journal 1 427-434.
3. Edwards G, Robertson WR & Morris ID 1988 Characterization of the regenerated Leydig cell population of the rat after destruction by ethylene-1,2-dimethanesulphonate. Journal of Endocrinology 117 11-18.
4. Hall PF 1985 Trophic stimulation of steroidogenesis: in search of the elusive trigger. Recent Progress in Hormone Research 41 1-59.
5. SCC: one enzyme with two actions: hydroxylase and lyase. Journal of Steroid Biochemistry and Molecular Biology 40 527-532.
6. Hardy MP, Zirkin BR & Ewing LL 1989 Kinetic studies on the development of the adult population of Leydig cells in the testes of the pubertal rat. Endocrinology 124 762-770.
7. Hardy MP, Kelce WR, Klinefelter GR & Ewing LL 1990 Differentiation of Leydig cell precursors in vitro: a role for androgen. Endocrinology 127 488-490.
8. Jackson AE, O'Leary PC, Ayers MM & de Kretser KM 1986 The effects of ethylene dimethane sulphonate (EDS) on rat Leydig cells: evidence to support a connective tissue origin of Leydig cells. Biology of Reproduction 35 425-437.
9. Jackson CM & Jackson H 1984 Comparative protective actions of gonadotrophins and testosterone against the antispermatogenic action of ethane dimethanesulfonate. Journal of Reproduction and Fertility 71 393-401.
10. Kerr JB, Donachie K & Rommerts FFG 1985 Selective destruction and regeneration of rat Leydig cells in vivo. Cell Tissue Research 242 145-156.
11. Kerr JB Bartlett JMS, Donachie K & Sharpe RM 1987 Origin of regenerating Leydig cells in the testis of the adult rat. Cell Tissue Research 249 367-377.
12. Klinefelter GR, Hall PF & Ewing LL 1987 Effect of luteinizing hormone deprivation in situ on steroidogenesis of rat Leydig cells purified by a multi step procedure. Biology of Reproduction 36 768-783.
13. McFarland KC, Sprengel R, Phillips HS, Kohler M, Rosemblit N, Nikolics K, Segaloff DL & Seeburg PH 1989 Lutropin chorio-gonadotropin receptor: an unusual member f of the G protein-coupled receptor family. Science 245 494-499.
14. Mendis-Handagama SMLC, Risbridger GP & de Kretser DM 1987 Morphometric analysis of the components of the neonatal and the adult rat testis interstitium. International Journal of Andrology 10 525-534.
15. Misrahi M, Beau I, Ghinea N, Vannier B, Loosfelt H, Meduri G, Vu Hai MT & Milgrom E 1996 The LH/CG and FSH receptors: different molecular forms and intracellular traffic. Molecular and Cellular Endocrinology 125 161-167.
16. Morris ID, Phillips DM & Bardin CW 1986 Ethylene dimethanesulfonate destroys Leydig cells in the rat testis. Endocrinology 118 709-719.
17. Myers RB & Abney TO 1990 Testosterone and androstanediol production by regenerating Leydig cells in the ethylene dimethane sulphonate-treated rat. International Journal of Andrology 13 4-16.
18. Myers RB & Abney TO 1991 Interstitial cell proliferation in the testis of the ethylene dimethane sulfonate-treated rat. Steroids 56 91-96.
19. 17-20 lyase cytochrome P-450. Journal of Biological Chemistry 259 3971-3976.
20. O'Shaughnessy PJ & Murphy L 1991 Steroidogenic enzyme activity in the rat testis following Leydig cell destruction by ethylene-1,2-dimethanesulphonate and during subsequent Leydig cell regeneration. Journal of Endocrinology 131 451-157.
21. Paync AH, Youngblood GL, Sha L, Burgos-Trinidad M & Hammond SH 1992 Hormonal regulation of steroidogenic enzyme gene expression in Leydig cells. Journal of Steroid Biochemistry and Molecular Biology 43 895-906.
22. Scc in rat adrenal gland. Proceedings of the National Academy of Sciences of the USA 80 702-706.
23. Reiter E, McNamara M, Closset J & Hennen G 1995 Expression and functionality of luteinizing hormone/ chorionic gonadotropin receptor in the rat prostate. Endocrinology 136 917-923.
24. Risbridger GP & Davies A 1994 Isolation of rat Leydig cells and precursor forms after administration of ethane dimethane sulfonate. American Journal of Physiology 266 E975-E979.
25. Russell LD, Corbin TJ, Ren HP, Amador A, Bartke A & Ghosh S 1992 Structural changes in rat Leydig cells post-hypophysectomy: a morphometric and endocrine study. Endocrinology 131 498-508.
26. Saez JM 1994 Leydig cells: endocrine, paracrine, and autocrine regulation. Endocrine Review 15 574-625.
27. Segaloff DL & Ascoli M 1993 The lutropin/choriogonadotropin receptor 4 years later. Endocrine Review 14 324-347.
28. Segaloff DL, Sprengel R, Nikolics K & Ascoli M 1990 The structure of the lutropin choriogonadotropin receptor. Recent Progress in Hormone Research 46 261-303.
29. Shan LX & Hardy MP 1992 Developmental changes in levels of luteinizing hormone receptor and androgen receptor in rat Leydig cells. Endocrinology 131 1107-1114.
30. Tapanainen J, Kupoio T, Pelliniemi LJ & Huhtaniemi I 1984 Rat testicular endogenous steroids and number of Leydig cells between the fetal period and sexual maturity. Biology of Reproduction 31 1027-1035.
31. Teerds KJ Closset J, Rommerts FFG, De Rooij DG, Stocco DM, Colenbrander B, Wensing GJG & Hennen G 1989 The effects of pure FSH and LH preparations on the number and function of Leydig cells in immature hypophysectomized rats. Journal of Endocrinology 120 97-106.
32. Tena-Sempere M, Zhang FP & Huhtaniemi I 1994 Persistent expression of a truncated form of the luteinizing hormone receptor messenger ribonucleic acid in the rat testis after selective Leydig cell destruction by ethylene dimethane sulfonate. Endocrinology 135 1018-1024.
33. Tena-Sempere M, Rannikko A, Kero J, Zhang FP & Huhtaniemi IT 1997 Molecular mechanisms of reappearance of luteinizing hormone receptor expression and function in rat testis after selective Leydig cell destruction by ethylene dimethane sulfonate. Endocrinology 138 3340-3348.
34. Veldhuizen-Tsoerkan MB, Ivell R & Teerds KJ 1994 hCG-induced changes in the LH/hCG receptor mRNA transcript levels in the testis of adult hypophysectomized, ethane dimethyl sulphonate-treated rats. Molecular and Cellular Endocrinology 105 37-44.
35. Vihko KK, Nishimori K, LaPolt PS & Hsueh JW 1992 Expression of testicular messenger ribonucleic acid for luteinizing hormone receptor in the rat: developmental regulation of multiple transcripts during postnatal life. Biology of Reproduction 46 1016-1020.
36. Vreeburg JTM, Oms MP, Rommerts RRG & Teerds KJ 1988 Functional properties of developing rat Leydig cells after treatment with ethylene dimethanesulphonate (EDS). Journal of Reproduction and Fertility 84 63-69.
37. Zhai J, Lanclos KD & Abney TO 1996 Estrogen receptor mRNA changes during Leydig cell development. Biology of Reproduction 55 782-788.