Skin necrosis at the injection site induced by low-molecular-weight heparin: Case report and review

Dermatology

Volumn 196, Issue 2, 1998, Pages 264-265

  Santamaría, Amparo ^a   Romani J ^a   Souto, J C ^a   Lopez A ^a   Mateo, J ^a   Fontcuberta, J ^a  

^a HOSPITAL DE LA SANTA CREU I SANT PAU   (Spain)

Author keywords

Antibodies to heparin platelet factor 4 complex; Low molecular weight heparins; Skin necrosis

Indexed keywords

LOW MOLECULAR WEIGHT HEPARIN; THROMBOCYTE FACTOR 4;

AGED; ARTICLE; CASE REPORT; FEMALE; HEART FAILURE; HUMAN; INJECTION SITE; PRIORITY JOURNAL; PROPHYLAXIS; SKIN NECROSIS;

AGED; AGED, 80 AND OVER; ANTICOAGULANTS; FEMALE; HEPARIN, LOW-MOLECULAR-WEIGHT; HUMANS; INJECTIONS, SUBCUTANEOUS; NECROSIS; SKIN; SKIN DISEASES;

EID: 0031909011     PISSN: 10188665     EISSN: None     Source Type: Journal    
DOI: 10.1159/000017889     Document Type: Article

References (10)

1. Rongioletti F, Pisany S, Ciaccio M, Rebora A: Skin necrosis due to intravenous heparin. Dermatologica 1989:178:47-50.
2. Balestra B, Quadri P, Demarmels Biasiutti F, Furlam M, Lämmle B: Low molecular weight heparin-induced thrombocytopenia and skin necrosis distant from injection sites. Eur J Haematol 1994;53: 61-63.
3. Manoharan A: Heparin-induced skin reaction with low molecular weight heparin. Eur J Haematol 1992;48:234.
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9. Real E, Grau E, Rubio M, Torrecilla T: Skin necrosis after subcutaneous low molecular weight heparin injection. Am J Hematol 1995;49:253-266.
10. Amiral J, Bridey F, Dreyfus M, Vissac AM, Fressinaud E, Wolf M, Meyer A: Platelet factor 4 complexed to heparin is the target for antibodies generated in heparin-induced thrombocytopenia. Thromb Haemost 1992;68:95-96.