Treatment of chronic, refractory cough with baclofen

Respiration

Volumn 65, Issue 1, 1998, Pages 86-88

  Dicpinigaitis, Peter V ^a,b   Rauf, Khalid ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b Albert Einstein Hospital   (United States)

Author keywords

Baclofen; Capsaicin; Cough; GABA

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR STIMULATING AGENT; ANTITUSSIVE AGENT; BACLOFEN; CAPSAICIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR;

ADULT; AGED; ARTICLE; CASE REPORT; CLINICAL FEATURE; CLINICAL TRIAL; CONTROLLED STUDY; COUGHING; DOUBLE BLIND PROCEDURE; FEMALE; HUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; PROVOCATION TEST; RANDOMIZED CONTROLLED TRIAL; TIME; TREATMENT OUTCOME;

ADMINISTRATION, ORAL; ADULT; AGED; BACLOFEN; BRONCHIAL PROVOCATION TESTS; CAPSAICIN; CHRONIC DISEASE; COUGH; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; FEMALE; GABA AGONISTS; HUMANS;

EID: 0031908998     PISSN: 00257931     EISSN: None     Source Type: Journal    
DOI: 10.1159/000029232     Document Type: Article

References (7)

1. Choudry NB, Fuller RW: Sensitivity of the cough reflex in patients with chronic cough. Eur Respir J 1992;5:296-300.
2. Ong J, Kerr DIB: GABA-receptors in peripheral tissues. Life Sci 1990;46:1489-1501.
3. Bolser DC, DeGennaro FC, O'Reilly S, Chapman RW, Kreutner W, Egan RW, Hey JA: Peripheral and central sites of action of GABA-B agonists to inhibit the cogh reflex in the cat and guinea pig. Br J Pharmacol 1994;113: 1344-1348.
4. Chapman RW, Hey JA, Rizzo CA, Bolser DC: GABA-B receptors in the lung. Trends Pharmacol Sci 1993;14:26-29.
5. Dicpinigaitis PV, Dobkin JB: Antitussive effect of the GABA-agonist baclofen. Chest 1997; 111:996-999.
6. Dicpinigaitis PV: Use of baclofen to suppress cough induced by angiotensin-converting enzyme inhibitors. Ann Pharmacother 1996;30: 1242-1245.
7. Dicpinigaitis PV, Spungen AM, Bauman WA, Absgarten A, Almenoff PL: Inhibition of bronchial hyperresponsiveness by the GABA-agonist baclofen. Chest 1994;106:758-761.