메뉴 건너뛰기




Volumn 5, Issue 3, 1998, Pages 388-393

In vitro and in vivo antisense-mediated growth inhibition of a mammary adenocarcinoma from MMTV-neu transgenic mice

Author keywords

Antisense therapy; Liposome; Mammary adenocarcinoma; MMTV neu; Transgenic mice

Indexed keywords

COMPLEMENTARY DNA; MESSENGER RNA;

EID: 0031908626     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3300592     Document Type: Article
Times cited : (16)

References (19)
  • 1
    • 0024796824 scopus 로고
    • Transgenic mice as probes into complex systems
    • Hanahan D Transgenic mice as probes into complex systems. Science 1989; 246: 1265-1275.
    • (1989) Science , vol.246 , pp. 1265-1275
    • Hanahan, D.1
  • 2
    • 0024457750 scopus 로고
    • Animal models of human disease. Pathology and molecular biology of spontaneous neoplasms occurring in transgenic mice carrying and expressing activated cellular oncogenes
    • Pattengale PK et al. Animal models of human disease. Pathology and molecular biology of spontaneous neoplasms occurring in transgenic mice carrying and expressing activated cellular oncogenes. Am J Pathol 1989; 135: 39-61.
    • (1989) Am J Pathol , vol.135 , pp. 39-61
    • Pattengale, P.K.1
  • 3
    • 0030444452 scopus 로고    scopus 로고
    • Tumor suppressor gene mutations in mice
    • Jacks T. Tumor suppressor gene mutations in mice. Annu Rev Genet 1996; 30: 603-636.
    • (1996) Annu Rev Genet , vol.30 , pp. 603-636
    • Jacks, T.1
  • 4
    • 0029165298 scopus 로고
    • Local regression of breast tumors following intramammary ganciclov̈ir administration in double transgenic mice expressing neu oncogene and herpes symplex virus thyrmidine kinase
    • Sacco MG et al. Local regression of breast tumors following intramammary ganciclov̈ir administration in double transgenic mice expressing neu oncogene and herpes symplex virus thyrmidine kinase. Gene Therapy 1995; 2: 493-497.
    • (1995) Gene Therapy , vol.2 , pp. 493-497
    • Sacco, M.G.1
  • 5
    • 12544260776 scopus 로고    scopus 로고
    • Partial regression, yet incomplete eradication of mammary tumors in transgenic mice by retrovirally mediated HSVtk transfer in vivo
    • Sacco MG et al. Partial regression, yet incomplete eradication of mammary tumors in transgenic mice by retrovirally mediated HSVtk transfer in vivo. Gene Therapy 1996; 3: 1151-1156.
    • (1996) Gene Therapy , vol.3 , pp. 1151-1156
    • Sacco, M.G.1
  • 6
    • 0026633920 scopus 로고
    • Early and multifocal tumors in breast, salivary, harderian and epididimal tissues developed in MMTV-Neu transgenic mice
    • Lucchini F et al. Early and multifocal tumors in breast, salivary, harderian and epididimal tissues developed in MMTV-Neu transgenic mice. Cancer Lett 1992; 64: 203-209.
    • (1992) Cancer Lett , vol.64 , pp. 203-209
    • Lucchini, F.1
  • 7
    • 0028670125 scopus 로고
    • The biology of erbB-2neu/HER-2 and its role in cancer
    • Hynes NE, Stern DF. The biology of erbB-2neu/HER-2 and its role in cancer. Biochem Biophys Acta 1994; 1198: 165-184.
    • (1994) Biochem Biophys Acta , vol.1198 , pp. 165-184
    • Hynes, N.E.1    Stern, D.F.2
  • 8
    • 0028290891 scopus 로고
    • The neu-oncogene: Signal transduction pathways, transformation mechanisms and evolving therapies
    • Dougall WC et al. The neu-oncogene: signal transduction pathways, transformation mechanisms and evolving therapies. Oncogene 1994; 9: 2109-2123.
    • (1994) Oncogene , vol.9 , pp. 2109-2123
    • Dougall, W.C.1
  • 9
    • 14444275536 scopus 로고    scopus 로고
    • Establishment and characterization of a new mammary adenocarcinoma cell line derived from MMTV neu transgenic mice
    • (in press)
    • Sacco MG et al. Establishment and characterization of a new mammary adenocarcinoma cell line derived from MMTV neu transgenic mice. Breast Cancer Res Treat (in press).
    • Breast Cancer Res Treat
    • Sacco, M.G.1
  • 10
    • 0023713558 scopus 로고
    • Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene
    • Muller WJ, Pattengale PK, Wallace R, Leder P. Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene. Cell 1988; 54: 105-115.
    • (1988) Cell , vol.54 , pp. 105-115
    • Muller, W.J.1    Pattengale, P.K.2    Wallace, R.3    Leder, P.4
  • 11
    • 0029997433 scopus 로고    scopus 로고
    • Activated neu induces rapid tumor progression
    • Guy CT, Cardiff RD, Muller WJ. Activated neu induces rapid tumor progression. J Biol Chem 1996; 271: 7673-7678.
    • (1996) J Biol Chem , vol.271 , pp. 7673-7678
    • Guy, C.T.1    Cardiff, R.D.2    Muller, W.J.3
  • 12
    • 0026721173 scopus 로고
    • Therapeutic applications of oligonucleotides
    • Crooke ST. Therapeutic applications of oligonucleotides. Annu Rev Pharmacol Toxicol 1993; 32: 329-376.
    • (1993) Annu Rev Pharmacol Toxicol , vol.32 , pp. 329-376
    • Crooke, S.T.1
  • 13
    • 19144363671 scopus 로고    scopus 로고
    • Selective gene therapy for proliferative disorders: Sense and antisense
    • Indolfi C Chiariello M, Avvedimento EV. Selective gene therapy for proliferative disorders: sense and antisense. Nature Med 1996; 2: 634-635.
    • (1996) Nature Med , vol.2 , pp. 634-635
    • Indolfi, C.1    Chiariello, M.2    Avvedimento, E.V.3
  • 14
    • 0029977448 scopus 로고    scopus 로고
    • Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against C-raf kinase
    • Monia BP et al. Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against C-raf kinase. Nature Med 1996, 2: 668-675.
    • (1996) Nature Med , vol.2 , pp. 668-675
    • Monia, B.P.1
  • 15
    • 0031056656 scopus 로고    scopus 로고
    • Suppression of SPARC expression by antisense RNA abrogates the tumorigenicity of human melanoma cells
    • Ledda MF et al. Suppression of SPARC expression by antisense RNA abrogates the tumorigenicity of human melanoma cells. Nature Med 1997; 3: 171-176
    • (1997) Nature Med , vol.3 , pp. 171-176
    • Ledda, M.F.1
  • 16
    • 0030855812 scopus 로고    scopus 로고
    • Antisense targeting of basic fibroblast growth factor receptor-1 in human melanomas blocks intrarumoral angiogenesis and tumor growth
    • Wang Y, Becker D. Antisense targeting of basic fibroblast growth factor receptor-1 in human melanomas blocks intrarumoral angiogenesis and tumor growth. Nature Med 1997; 3: 887-893.
    • (1997) Nature Med , vol.3 , pp. 887-893
    • Wang, Y.1    Becker, D.2
  • 17
    • 0029145127 scopus 로고
    • Antisense DNA downregulation of the ERBB2 oncogene measured by a flow cytometric assay
    • Vaughn JP et al. Antisense DNA downregulation of the ERBB2 oncogene measured by a flow cytometric assay. Proc Natl Acad Sci USA 1995; 92: 8338-8342.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8338-8342
    • Vaughn, J.P.1
  • 18
    • 0026023289 scopus 로고
    • Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice
    • Soriano P, Montgomery C, Geske R, Bradley A. Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice. Cell 1991; 64: 693-702.
    • (1991) Cell , vol.64 , pp. 693-702
    • Soriano, P.1    Montgomery, C.2    Geske, R.3    Bradley, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.