The immunophenotype of adult acute myeloid leukemia: High frequency of lymphoid antigen expression and comparison of immunophenotype, French- American-British classification, and karyotypic abnormalities

American Journal of Clinical Pathology

Volumn 109, Issue 2, 1998, Pages 211-220

  Khalidi, Hasan S ^a   Medeiros, L Jeffrey ^a   Chang, Karen L ^a   Brynes, Russell K ^a   Slovak, Marilyn L ^a   Arber, Daniel A ^a  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

Acute myeloid leukemia; Cytogenetics; Flow cytometry; French American British Cooperative Group classification; Immunophenotyping

Indexed keywords

CD33 ANTIGEN; CD45 ANTIGEN; MICROSOMAL AMINOPEPTIDASE;

ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LEUKEMIA; ADULT; AGED; ANTIGEN EXPRESSION; ARTICLE; CANCER CLASSIFICATION; CHROMOSOME TRANSLOCATION; CYTOGENETICS; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOPHENOTYPING; KARYOTYPE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL;

EID: 0031908246     PISSN: 00029173     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcp/109.2.211     Document Type: Article

References (42)

1. Bennett JM, Catovsky D, Daniel M, et al. Proposals for the classification of the acute leukemias. Br J Haematol. 1976;33:451-458.
2. Bennett JM, Catovsky D, Daniel MT, et al. Proposed revised criteria for the classification of acute myeloid leukemia: a report of the French-American-British Cooperative Group. Ann Intern Med. 1985;103:626-629.
3. Bennett JM, Catovsky D, Daniel M, et al. Proposal for the recognition of minimally differentiated acute myeloid leukaemia (AML-M0). Br J Haematol. 1991;78:325-329.
4. Second MIC Cooperative Study Group. Morphologic, immunologic, and cytogenetic (MIC) working classification of the acute myeloid leukemias. Report of the Workshop held in Leuven, Belgium, September 15-17, 1986. Cancer Genet Cytogenet. 1988;30:1-15.
5. First MIC Cooperative Study Group. Morphologic, immunologic and cytogenetic (MIC) working classification of acute lymphoblastic leukemias. Report of the workshop held in Leuven, Belgium, April 22-23, 1985. Cancer Genet Cytogenet. 1986;23:189-197.
6. Neame PB, Soamboonsrup P, Browman GP, et al. Classifying acute leukemia by immunophenotyping: a combined FAB-immunologic classification of AML. Blood. 1986;68:1355-1362.
7. Bene MC, Castoldi G, Knapp W, et al. Proposal for the immunologic classification of acute leukemias. Leukemia. 1995;9:1783-1786.
8. Kaplan SS, Penchansky L, Stolc V, et al. Immunophenotyping in the classification of acute leukemia in adults: interpretation of multiple lineage reactivity. Cancer. 1989;63:1520-1527.
9. Traweek ST. Immunophenotypic analysis of acute leukemia. Am J Clin Pathol. 1993;99:504-512.
10. Drexler HG, Thiel E, Ludwig W-D. Acute myeloid leukemias expressing lymphoid-associated antigens: diagnostic incidence and prognostic significance. Leukemia. 1993;7:489-198.
11. Reading CL, Estey EH, Huh YO, et al. Expression of unusual immunophenotype combinations in acute myelogenous leukemia. Blood. 1993;81:3083-3090.
12. Launder TM, Bray RA, Stempora L, et al. Lymphoid-associated antigen expression by acute myeloid leukemia. Am J Clin Pathol. 1996;106:185-191.
13. Head DR. Revised classification of acute myeloid leukemia. Leukemia. 1996;10:1826-1831.
14. Paietta E, Wiernik PH, Andersen J, et al. Acute myeloid leukemia M4 with inv(16) (p13q22) exhibits a specific immunophenotype with CD2 expression. Blood. 1993;82:2595.
15. Claxton DF, Reading CL, Nagarajan L, et al. Correlation of CD2 expression with PML gene breakpoints in patients with acute promyelocytic leukemia. Blood. 1992;80:582-586.
16. Rovelli A, Biondi A, Rajnoldi AC, et al. Microgranular variant of acute promyelocytic leukemia in children. J Clin Oncol. 1992;10:1413-1418.
17. Kita K, Nakase K, Miwa H, et al. Phenotypical characteristics of acute myelocytic leukemia associated with the t(8;21)(q22;q22) chromosomal abnormality: frequent expression of immature B-cell antigen CD19 together with stem cell antigen CD34. Blood. 1992;80:470-477.
18. Hurwitz CA, Raimondi SC, Head D, et al. Distinctive immunophenotypic features of t(8;21)(q22;q22) acute myeloblastic leukemia in children. Blood. 1992;80:3182-3188.
19. Porwit-MacDonald A, Janossy G, Ivory K, et al. Leukemia-associated changes identified by quantitative flow cytometry: IV. CD34 expression in acute myelogenous leukemia M2 with t(8;21). Blood. 1996;87:1162-1169.
20. Bennett JM, Catovsky D, Daniel M, et al. Criteria for the diagnosis of acute leukemia of megakaryocytic lineage (M7): a report of the French-American-British Cooperative Group. Ann Intern Med. 1985;103:460-462.
21. Borowitz MJ, Guenther KL, Shults KE, et al. Immunophenotyping of acute leukemia by flow cytometric analysis: use of CD45 and right-angle light scatter to gate on leukemic blasts in three-color analysis. Am J Clin Pathol. 1993;100:534-540.
22. Mitelman F, ed. An International System for Human Cytogenetic Nomenclature. Basel, Switzerland: S Karger; 1995.
23. Vinante F, Pizzolo G, Rigo A, et al. The CD4 molecule belongs to the phenotypic repertoire of most cases of acute myeloid leukemia. Leukemia. 1992;6:1257-1262.
24. Alsabeh R, Brynes RK, Slovak ML, et al. Acute myeloid leukemia with t(6;9) (p23;q34): association with myelodysplasia, basophilia, and initial CD34 negative immunophenotype. Am J Clin Pathol. 1997;107:430-437.
25. Arber DA, Glackin C, Lowe G, et al. Presence of t(8;21)(q22;q22) in myeloperoxidase-positive, myeloid surface antigen-negative acute myeloid leukemia. Am J Clin Pathol. 1997;107:68-73.
26. Bradstock K, Matthews J, Benson E, et al. Prognostic value of immunophenotyping in acute myeloid leukemia. Blood. 1994;84:1220-1225.
27. Urbano-Ispizua A, Matutes E, Villamor N, et al. The value of detecting surface and cytoplasmic antigens in acute myeloid leukaemia. Br J Haematol. 1992;81:178-183.
28. Kita K, Miwa H, Nakase K, et al. Clinical importance of CD7 expression in acute myelocytic leukemia. Blood. 1993;81:2399-2405.
29. Vidriales MB, Orfao A, González M, et al. Expression of NK and lymphoid-associated antigens in blast cells of acute myeloblastic leukemia. Leukemia. 1993;7:2026-2029.
30. Del Poeta G, Stasi R, Venditti A, et al. Prognostic value of cell marker analysis in de novo acute myeloid leukemia. Leukemia. 1994;8:388-394.
31. Ball ED, Davis RB, Griffin JD, et al. Prognostic value of lymphocyte surface markers in acute myeloid leukemia. Blood. 1991;77:2242-2250.
32. Cross AH, Goorha RM, Nuss R, et al. Acute myeloid leukemia with T-lymphoid features: a distinct biologic and clinical entity. Blood. 1988;72:579-587.
33. Solary E, Casasnovas R-O, Campos L, et al. Surface markers in adult acute myeloblastic leukemia: correlation with CD19+, CD34+ and CD14+/DR- phenotypes with shorter survival. Leukemia. 1992;6:393-399.
34. Terstappen LWMM, Safford M, Könemann S, et al. Flow cytometric characterization of acute myeloid leukemia: Part II. Phenotypic heterogeneity at diagnosis. Leukemia. 1991;5:757-767.
35. Betz SA, Foucar K, Head DR, et al. False-positive flow cytometric platelet glycoprotein IIb/IIIa expression in myeloid leukemias secondary to platelet adherence to blasts. Blood. 1992;9:2399-2403.
36. Scott AA, Head DR, Kopecky KJ, et al. HLA-DR-, CD33+, CD56+, CD16- myeloid/natural killer cell acute leukemia: a previously unrecognized form of acute leukemia potentially misdiagnosed as French-American-British acute myeloid leukemia-M3. Blood. 1994;84:244-255.
37. Reuss-Borst MA, Steinke B, Waller HD, et al. Phenotypic and clinical heterogeneity of CD56-positive acute nonlymphoblastic leukemia. Ann Hematol. 1992;64:78-82.
38. Drexler HG. Classification of acute myeloid leukemias: a comparison of FAB and immunophenotyping. Leukemia. 1987;1:687-705.
39. Brandt JT, Tisone JA, Bohman JE, et al. Aberrant expression of CD19 as a marker of monocytic lineage in acute myelogenous leukemia. Am J Clin Pathol. 1997;107:283-291.
40. Cuneo A, Michaux J-L, Ferrant A, et al. Correlation of cytogenetic patterns and clinicobiological features in adult acute myeloid leukemia expressing lymphoid markers. Blood. 1992;79:720-727.
41. Cuneo A, Ferrant A, Michaux J-L, et al. Clinical review on features and cytogenetic patterns in adult acute myeloid leukemia with lymphoid markers. Leukemia Lymphoma. 1993;9:285-291.
42. Tien H-F, Wang C, Chen YC, et al. Characterization of acute myeloid leukemia (AML) coexpressing lymphoid markers: different biologic features between T-cell antigen positive and B-cell antigen positive AML. Leukemia. 1993;7:688-695.