Permeability, cytotoxicity, and genotoxicity of chromium(V) and chromium(VI) complexes in V79 chinese hamster lung cells

Chemical Research in Toxicology

Volumn 11, Issue 2, 1998, Pages 119-129

  Dillon, Carolyn T ^a   Lay, Peter A ^a   Bonin, Antonio M ^b   Cholewa, Marian ^c,d   Legge, George J F ^c   Collins, Terrence J ^e   Kostka, Kimberly L ^e  

^a UNIVERSITY OF SYDNEY   (Australia)

^b National Institute of Occupational Health and Safety   (Australia)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d INSTITUTE OF NUCLEAR PHYSICS   (Poland)

^e CARNEGIE MELLON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMIUM DERIVATIVE;

ANIMAL CELL; ARTICLE; CELL STRAIN V 79; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CULTURE MEDIUM; DRUG CARCINOGENICITY; DRUG CYTOTOXICITY; DRUG DISTRIBUTION; DRUG PENETRATION; GENOTOXICITY; MICRONUCLEUS TEST; NONHUMAN;

ANIMALS; CARCINOGENS; CELL MEMBRANE PERMEABILITY; CELLS, CULTURED; CHROMIUM COMPOUNDS; CRICETINAE; CRICETULUS; DNA DAMAGE; LUNG; MICRONUCLEUS TESTS; NEOPLASMS; TOXICITY TESTS;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS; MAMMALIA;

EID: 0031907785     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx9701541     Document Type: Article

References (72)

1. IARC. (1990) IARC Monographs on the Evaluation of Carcinogenic Risk to Humans: Chromium, Nickel and Welding, Vol. 49, pp 49-508, International Agency for Research on Cancer, Lyon, France.
2. Nriagu, J. O., and Nieboer, E. (1988) Chromium in the Natural and Human Environments, Wiley, New York.
3. Langård, S. (1982) Biological and Environmental Aspects of Chromium, Elsevier Biomedical, Amsterdam.
4. Burrows, D. (1983) Chromium: Metabolism and Toxicity; CRC, Boca Raton, FL.
5. Cohen, M. D., Kargacin, B., Klein, C. B., and Costa, M. (1993) Mechanisms of chromium carcinogenicity and toxicity. Crit. Rev. Toxicol. 23, 225-281.
6. De Flora, S., Bagnasco, M., Serra, D., and Zanacchi, P. (1990) Genotoxicity of chromium compounds. A review. Mutat. Res. 238, 99-172.
7. Howard, W. R., Hoffman, S. A., and Kochhar, T, S, (1992) Enhanced production of micronuclei by hexavalent chromium in cultured CHO cells. Bull. Environ. Contam. Toxicol. 49, 535- 540.
8. Léonard, A., and Lauwerys, R. R. (1980) Carcinogenicity and mutagenicity of chromium. Mutat. Res. 76, 227-239.
9. Bryson, W. G., and Goodall, C. M. (1981) Improved spectrophotometric determination of chromium in animal tissue digests with diphenylcarbazide. Anal. Chim. Acta 124, 391-401.
10. Levis, A. G., Bianchi, V., Tamino, G., and Pegoraro, B. (1978) Cytotoxic effects of hexavalent and trivalent chromium on mammalian cells in vitro. Br. J. Cancer 37, 386-396.
11. Dillon, C. T., Lay, P. A., Cholewa, M., Legge, G. J. F., Bonin, A. M., Collins, T. J., Kostka, K. L., and Shea-McCarthy, G. (1997) Microprobe X-ray absorption spectroscopic determination of the oxidation state of intracellular chromium following exposure of V79 Chinese hamster lung cells to genotoxic chromium complexes. Chem. Res. Toxicol. 10, 533-535.
12. Connett, P. H., and Wetterhahn, K. E. (1983) Metabolism of the carcinogen chromate by cellular constituents. Struct. Bonding (Berlin) 54, 93-124.
13. Arslan, P., Beltrame, M., and Tomasi, A. (1987) Intracellular chromium reduction. Biochim. Biophys. Acta 931, 10-15.
14. Farrell, R. P., Judd, R. J., Lay, P. A., Dixon, N, E., Baker, R. S. U., and Bonin, A. M. (1989) Chromium(V)-induced cleavage of DNA: Are chromium(V) complexes the active carcinogens in chromium(VI)-induced cancers? Chem. Res. Toxicol. 2, 227-229.
15. Kortenkamp, A., Ozolins, Z., Beyersmann, D., and O'Brien, P. (1989) Generation of PM2 DNA breaks in the course of reduction of chromium(VI) by glutathione. Mutat. Res. 216, 19-26.
16. Farrell, R. P., Judd, R. J., Lay, P. A., Bramley, R, and Ji, J.-Y. (1989) Ligand exchange and reduction reactions of oxochromate(V) complexes: Characterization of the common chromium(V) intermediates in the reductions of chromium(VI) and of transbis(2-ethyl-2-hydroxybutanoato(2-))oxochromate(V) by oxalic acid. Inorg, Chem. 28, 3401-3403.
17. Bramley, R., Farrell, R. P., Ji, J.-Y., and Lay, P. A. (1990) Ligand exchange and redox reactions of chromium(V): Isolation of the chromium(V) oxalato complexes from the ligand exchange reaction of bis[2-ethyl-2-hydroxybutanoato(2-)]oxochromate(V) with oxalate in 50% aqueous acetic acid. Aust. J. Chem. 43, 263-279.
18. Bramley, R., Ji, J.-Y., and Lay, P. A. (1991) Ligand-exchange reactions of chromium(V): Characterization of the ligand-exchange equilibria of bis(2-ethyl-2-hydroxybutanoato(2-))oxochromate(V) in aqueous 1,2-ethanediol and the solution structure of bis(1,2-ethanediolato(2-))oxochromate(V). Inorg. Chem. 30, 1557-1564.
19. Martin, B. D. (1989) Studies on the mechanism and prevention of chromium induced cancer. BSc (Honors) Thesis, University of Sydney, NSW, Australia.
20. 2COO}]. Inorg. Chem. 31, 4906-4908.
21. Dillon, C. T., Lay, P. A., Bonin, A. M., Dixon, N. E., Collins, T. J., and Kostka, K. L. (1993) In vitro DNA damage and mutations induced by a macrocyclic tetraamide chromium(V) complex: Implications for the role of Cr(V) peptide complexes in chromium-induced cancers. Carcinogenesis 14, 1875-1888.
22. Dillon, C. T. (1995) The role of Cr(V) complexes in chromiuminduced genotoxicities. PhD Thesis, University of Sydney, NSW, Australia.
23. Biedermann, K. A., and Landolph, J. R. (1990) Role of valence state and solubility of chromium compounds on induction of cytotoxicity, mutagenesis and anchorage independence in diploid human fibroblasts. Cancer Res. 50, 7835-7842.
24. Gray, S. J., and Sterling, K. (1950) The tagging of red cells and plasma proteins with radioactive chromium. J. Clin. Invest. 29, 1604-1613.
25. Debetto, P., Arslan, P., Antolini, M., and Luciani, S. (1988) Uptake of chromate by rat thymocytes and role of glutathione in its cytoplasmic reduction. Xenobiotica 18, 657-664.
26. Popper, H. H., Grygar, E., Ingolic, E., and Wawschinek, O. (1993) Cytotoxicity of chromium-III and -VI compounds. I. In vitro studies using different cell culture systems. Inhalat, Toxicol. 5, 345-369.
27. Kortenkamp, A., Beyersmann, D., and O'Brien, P. (1987) Uptake of chromium(III) complexes by erythrocytes. Toxicol. Environ. Chem. 14, 23-32.
28. Debetto, P., Lazzarini, A., Tomasi, A., Beltrame, M., and Arslan, P. (1986) Chromate uptake and oxidation state of intracellular chromium in rat thymocytes. Cell Biol. Int. Rep. 10, 214.
29. Bianchi, V., and Levis, A. G. (1987) Recent advances in chromium genotoxicity. Toxicol. Environ. Chem. 15, 1-24.
30. Elias, Z., Poirot, O., Schneider, O., Danière, M. C., Terzetti, F., Guedenet, J. C., and Cavelier, C. (1986) Cellular uptake, cytotoxic and mutagenic effects of insoluble chromic oxide in V79 Chinese hamster cells. Mutat. Res. 169, 159-170.
31. Warren, G., Schultz, P., Bancroft, D., Bennett, K., Abbott, E. H., and Rogers, S. (1981) Mutagenicity of a series of hexacoordinate chromium(III) compounds. Mutat. Res. 90, 111-118.
32. Sugden, K. D., Burris, R. B., and Rogers, S. J. (1990) An oxygen dependence in chromium mutagenesis. Mutat. Res. 244, 239-244.
33. Beyersmann, D., and Köster, A. (1987) On the role of trivalent chromium in chromium genotoxicity. Toxicol. Environ. Chem. 14, 11-22.
34. Cholewa, M., Legge, G. J. F., Weigold, H., Holan, G., and Birch, C. (1993) The use of a scanning proton microprobe in AIDS research. Nucl. Instrum. Methods Phys. Res., Sect. B B77, 282- 286.
35. Landsberg, J. P., McDonald, B., and Watt, F. (1992) Absence of aluminium in neuritic plaque cores in Alzheimer's disease. Nature (London) 360, 65-68.
36. Lindh, U., Sunde, T., Juntti-Berggren, L., Berggren, P.-O., and Pålsgård, E. (1991) Nuclear microscopy and the application to diabetes research. Nucl. Instrum. Methods Phys. Res., Sect. B B56/ 57, 1279-1283.
37. Lindh, U. (1993) Nuclear microscopy in trace-element biology from cellular studies to the clinic. Nucl. Instrum. Methods Phys. Res., Sect. B B77, 261-267.
38. Cholewa, M., Turnbull, I. F., Legge, G. J. F., Weigold, H., Marcuccio, S. M., Holan, G., Tomlinson, E., Wright, P. J., Dillon, C. T., Lay, P. A., and Bonin, A. M. (1995) Investigation of the uptake of drugs, carcinogens and mutagens by individual mammalian cells using a scanning proton microprobe. Nucl. Instrum. Methods Phys. Res., Sect. B B104, 317-323.
39. Fenech, M., and Morley, A. A. (1985) Measurement of micronuclei in lymphocytes. Mutat. Res. 147, 29-36.
40. Fenech, M., and Morley, A. (1985) Solutions to the kinetic problem in the micronucleus assay. Cytobios 43, 233-246.
41. Lasne, C., Gu, Z. W., Venegas, W., and Chouroulinkov, I. (1984) The in vitro micronucleus assay for detection of cytogenetic effects induced by mutagen-carcinogens : Comparison with the in vitro sister-chromatid exchange assay. Mutat. Res. 130, 273-282.
42. Matsuoka, A., Yamazaki, N., Suzuki, T., Hayashi, M., and Sofuni, T, (1993) Evaluation of the micronucleus test using a Chinese hamster cell line as an alternative to the conventional in vitro chromosomal aberration test. Mutat. Res. 272, 223-236.
43. Legator, M. S., and Au, W. W. (1994) Application of integrated genetic monitoring: The optimal approach for detecting environmental carcinogens. Environ. Health Perspect. 102, 125-132.
44. Raj, A. S., and Heddle, J. A. (1980) Simultaneous detection of chromosomal aberrations and sister-chromatid exchanges. Experience with DNA intercalating agents. Mutat. Res. 78, 253-260.
45. Heddle, J. A., Hite, M., Kirkhart, B., Mavournin, K., MacGregor, J. T., Newell, G. W., and Salamone, M. F. (1983) The induction of micronuclei as a measure of genotoxicity. A report of the U.S. environmental protection agency gene-tox program. Mutat. Res. 123, 61-118.
46. Krumpolc, M., and Roček, J. (1979) Synthesis of stable chromium(V) complexes of tertiary hydroxy acids. J. Am. Chem. Soc. 101, 3206-3209.
47. 18O-labeling reagent and a structure with four nonplanar amides. Inorg. Chem. 29, 3433-3436.
48. Collins, T. J. (1994) Designing ligands for oxidizing complexes. Acc. Chem. Res. 27, 279-285.
49. Inskeep, R. G., and Bjerrum, J. (1961) Preliminary investigations of the reactions of the hexaquo chromium(III) ion with α,α'- dipyridyl and with o-phenanthroline. Acta Chem. Scand. 15, 62- 68.
50. Inskeep, R. G., and Benson, M. (1961) Further studies of the hexaquo chromium(III) ion o-phenanthroline reaction. J. Inorg. Nucl. Chem. 20, 290-294.
51. Ford, D. K., and Yerganian, G. (1958) Observations on the chromosomes of Chinese hamster cells in tissue culture. J. Natl. Cancer Inst. 21, 393-425.
52. Bakke, O., Jakobsen, K., and Eik-Nes, K. B. (1984) Concentrationdependent effects of potassium dichromate on the cell cycle. Cytometry 5, 482-486.
53. Blankenship, L. J., Manning, F. C. R., Orenstein, J. M., and Patierno, S. R. (1994) Apoptosis is the mode of cell death caused by carcinogenic chromium. Toxicol. Appl. Pharmacol. 126, 75-83.
54. Kirby, B. J., and Legge, G. J. F. (1993) The preparation of biological tissue for a trace element analysis on the proton microprobe. Nucl. Instrum. Methods Phys. Res., Sect. B B77, 268-274.
55. Allan, G. L., Camakaris, J., and Legge, G. J. F. (1991) The elemental analysis of normal and Menkes' fibroblast cells with the SPMP. Nucl. Instrum. Methods Phys. Res., Sect. B B54, 175-179.
56. Legge, G. J. F. (1980) Elemental microanalysis of biological and medical specimens with a scanning proton microprobe. Nucl. Instrum. Methods Phys. Res. 168, 563-569.
57. Legge, G. J. F., McKenzie, C. D., and Mazzolini, A. P. (1979) The Melbourne proton microprobe. J. Microsc. (Oxford) 117, 185-200.
58. Legge, G. J. F., and Hammond, I. (1979) Total quantitative recording of elemental maps and spectra with a scanning microprobe. J. Microsc. (Oxford) 117, 201-210.
59. Galactic (1996) Win-IR Bio-Rad Reference Manual, Digilab Division, Bio-Rad Laboratories, Inc., Cambridge, MA.
60. Paschoa, A. S., Wrenn, M. E., Bruenger, F. W., Cholewa, M., and Jones, K. W. (1984) Some uncertainties associated with self-calibration in microPIXE analysis. Presented at the Fifth International Conference on Nuclear Methods in Environmental and Energy Research, Mayaguez, Puerto Rico.
61. Cholewa, M., Bench, G., Kirby, B. J., and Legge, G. J. F. (1991) Changes in organic materials with scanning particle microbeams. Nucl. Instrum. Methods Phys. Res., Sect. B B54, 101-108.
62. Sealock, R. M., Jamieson, D. N., and Legge, G. J. F. (1987) Scanning transmission microscopy with a 2 MeV alpha particle microbeam. Nucl. Instrum. Methods Phys. Res., Sect. B B29, 557-566.
63. Fenech, M. (1993) The cytokinesis-block micronucleus technique and its application to genotoxicity studies in human populations. Environ. Health Perspect. 101, 101-107.
64. Pagano, M., and Gauvreau, K. (1993) Principles of Biostatistics, Duxbury, Belmont.
65. Dawson-Saunders, B., and Trapp, R. G. (1990) Basic and Clinical Biostatistics, Appleton and Lange, East Norwalk.
66. GraphPad Software, Inc. (1993) GraphPad Instat, GraphPad Software, San Diego, CA.
67. Cholewa, M., Legge, G. J. F., Weigold, H., Holan, G., and Birch, C. J. (1994) The use of a scanning proton microprobe to observe anti-HIV drugs within cells. Life Sci. 54, 1607-1612.
68. Keeton, W. T., and Gould, J. L. (1986) Biological Science, 4th ed., W. W. Norton, New York.
69. Costa, M., Cantoni, O., de Mars, M., and Swartzendruber, D. E. (1982) Toxic metals produce an S-phase specific cell cycle block. Res. Commun. Chem. Pathol. Pharmacol. 38, 405-419.
70. Brochiero, E., Bonaly, J., and Mestre, J. C. (1984) Toxic action of hexavalent chromium on Euglena gracilis cells strain Z grown under heterotrophic conditions. Arch. Environ. Contam. Toxicol. 13, 603-608.
71. Jakobsen, K., Bakke, O., Østgaard, K., White, L. R., and Eiknes, K. B. (1982) Effects of potassium dichromate on the cell cycle of an established human cell line (NHIK 3025). Toxicology 24, 281-292.
72. Buttner, B., and Beyersmann, D. (1985) Modification of the erythrocyte anion carrier by chromate. Xenobiotica 15, 735-741.