β-adrenergic blockade does not prevent polycythemia or decrease in plasma volume in men at 4300 m altitude

European Journal of Applied Physiology and Occupational Physiology

Volumn 77, Issue 3, 1998, Pages 264-270

  Grover, R F ^b   Selland, M A ^b   McCullough, R G ^b   Dahms, T E ^d   Wolfel, E E ^b   Butterfield, G E ^c   Reeves, J T ^b   Greenleaf, J E ^a  

^a NASA AMES RESEARCH CENTER   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c VA PALO ALTO HEALTH CARE SYSTEM   (United States)

^d SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Blood volume; Erythropoietin; Hypoxia; Propranolol; Red cell volume

Indexed keywords

BETA ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CARBON MONOXIDE; ERYTHROPOIETIN; PROPRANOLOL;

ADRENERGIC RECEPTOR BLOCKING; ADRENERGIC SYSTEM; ADULT; ALTITUDE; ARTICLE; BLOOD VOLUME; BODY WATER; CLINICAL ARTICLE; CONTROLLED STUDY; ERYTHROCYTE; ERYTHROCYTE VOLUME; HEART OUTPUT; HEMATOCRIT; HUMAN; HUMAN EXPERIMENT; HYPOVOLEMIA; HYPOXIA; MALE; NORMAL HUMAN; OXYGEN SATURATION; PLASMA VOLUME; POLYCYTHEMIA; PRIORITY JOURNAL; RETICULOCYTE COUNT; WEIGHT REDUCTION;

NASA CENTER ARC; NASA DISCIPLINE REGULATORY PHYSIOLOGY;

ADRENERGIC BETA-ANTAGONISTS; ADULT; ALTITUDE; ANOXIA; BLOOD VOLUME; ERYTHROPOIESIS; ERYTHROPOIETIN; HUMANS; MALE; PLASMA VOLUME; POLYCYTHEMIA; PROPRANOLOL;

EID: 0031907299     PISSN: 03015548     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004210050331     Document Type: Article

References (27)

1. Anand IS, Chandrashekhar Y, Rao SK, Ferrai R, Chandana J, Ramesh B, Shetty KJ, Bhoparai MS (1993) Body fluid compartments, renal blood flow and hormones at 6000 m in normal subjects. J Appl Physiol 74:1234-1239
2. Bender PR, Groves BM, McCullough RE, McCullouch RG, Huang S-Y, Hamilton AJ, Wagner PD, Cymerman A, Reeves JT (1988) Oxygen transport to exercising leg in chronic hypoxia. J Appl Physiol 65:2592-2597
3. Butterfield GE, Gates J, Fleming S, Brooks GA, Sutton JR, Reeves JT (1992) Increased energy intake minimizes weight loss in men at high altitude. J Appl Physiol 72:1741-1748
4. Claybaugh JR, Brooks DP, Cymerman A (1992) Hormonal control of fluid and electrolyte balance at high altitude in normal subjects. In: Sutton JR, Coates G, Houston CS (eds) Hypoxia and mountain medicine. Pergamon Press, Oxford, pp 61-72
5. Dahms TE, Horvath SM (1974) Rapid, accurate technique for determination of carbon monoxide in blood. Clin Chem 20:533-537
6. Dill DB, Horvath SM, Dahms TE, Parker RE, Lynch JR (1969) Hemoconcentration at altitude. J Appl Physiol 27:514-518
7. Faura J, Reynafarje C (1970) Uso de la metandrostenolona para acelerar la eritropoyesis en la exposicion a la altura. Arch Inst Biol Andina (Lima) 3:94-98
8. Fink GD, Fisher JW (1977) Role of the sympathetic nervous system in the control of erythropoietin production. In: Fisher JW (ed) Kidney hormones vol 2, Erythropoietin. Academic Press, New York, pp 387-413
9. Greenleaf JE, Convertino VA, Mangseth GR (1979) Plasma volume during stress in man: osmolality and red cell volume. J Appl Physiol 47:1031-1038
10. Hollenberg NK, Adams DF, McKinstry DN, Williams GH, Borucki LJ, Sullivan JM (1979) Beta-adrenocepter-blocking agents and the kidney: effect of nadolol and propranolol on the renal circulation. Br J Clin Pharmacol 7 [Suppl 2]:219S-225S
11. Hoyt RW, Honig A (1996) Body fluid and energy metabolism at high altitude. In: Fregly MJ, Blattes CM (eds) Handbook of physiology: Section 4: Environmental physiology. V. The terrestrial altitude environment. Oxford University Press, New York, pp 1277-1289
12. Huang S-Y, Alexander JK, Grover RF, Maher JT, McCullough RE, McCullough RG, Moore LG, Weil JV, Sampson JB, Reeves JT (1984) Increased metabolism contributes to increased resting ventilation at high altitude. Respir Physiol 57:377-385
13. Hughson RL, Yamamoto Y, McCullough RE, Sutton JR, Reeves JT (1994) Sympathetic and parasympathetic indicators of heart rate control at altitude studied by spectral analysis. J Appl Physiol 77:2537-2542
14. Lyons TP, Muza SR, Rock PB, Cymerman A (1995) The effect of altitude pre-acclimation on acute mountain sickness during reexposure. Aviat Space Environ Med 66:957-962
15. Mazzeo RS, Brooks GA, Butterfield GE, Cymerman A, Roberts AC, Selland M, Wolfel EE, Reeves JT (1994a) b-adrenergic blockade does not prevent the lactate response to exercise after acclimatization to high altitude. J Appl Physiol 76:610-615
16. Mazzeo RS, Wolfel EE, Butterfield GE, Reeves JT (1994b) Sympathetic response during 21 days at high altitude (4300m) as determined by urinary and arterial catecholamines. Metabolism 43:1226-1232
17. Moore LC, Harrison GL, McCullough RE, Micco AJ, Tucker A, Weil JV, Reeves JT (1986a) Low acute hypoxic ventilatory response and hypoxic depression in acute mountain sickness. J Appl Physiol 60:1407-1412
18. Moore LC, Cymerman A, Huang S-Y, McCullough RE, McCullough RG, Rock PB, Young A, Young PM, Bloedow D, Weil JV, Reeves JT (1986b) Propranolol does not impair exercise oxygen uptake in normal men at high altitude. J Appl Physiol 61:1935-1941
19. Myhre LG, Dill DB, Hall FG, Brown DK (1970) Blood volume chances during three-week residence at high altitude. Clin Chem 16:7-14
20. Ostadal B, Ressl J, Urbanovç D, Widimsky J, Prochçzka J, Pelouch V (1978) The effect of beta adrenergic blockade on pulmonary hypertension, right ventricular hypertrophy, and polycythemia, induced in rats by intermittent high altitude hypoxia. Basic Res Cardiol 73:422-432
21. Paillard F, Lantz B, Leviel F, Ardaillou R (1986) Renal hemodynamic effects of tertatolol in essential hypertension. Am J Nephrol 6 [Suppl 2]:40-44
22. Richalet J-P, Souberbielle J-C, Antezana A-M, Dechaux M, Le Trong J-L, Bienvenu A, Daniel F, Blanchot C, Zittoun J (1994) Control of erythropoiesis in humans during prolonged exposure to the altitude of 6542m. Am J Physiol 266:R756-R764
23. Surks MI, Chinn KSK, Matoush LR (1966) Alterations in body composition in man after acute exposure to high altitude. J Appl Physiol 21:1741-1746
24. 125I-albumin and the T 1824 technique. Scand J Clin Lab Invest 51:185-190
25. Voelkel NF, McMurtry IF, Reeves JT (1980) Chronic propranolol treatment blunts right ventricular hypertrophy in rats at high altitude. J Appl Physiol 48:473-476
26. Wolfel EE, Groves BM, Brooks GA, Butterfield GE, Mazzeo RS, Moore LG, Sutton JR, Bender PR, Dahms TE, McCullough RE, McCullough RG, Huang S-Y, Sun S-F, Grover RF, Hultgren HN, Reeves JT (1991) Oxygen transport during steady-state submaximal exercise in chronic hypoxia. J Appl Physiol 70:1129-1136
27. Wolfel EE, Selland MA, Mazzeo RS, Reeves JT (1994) Systemic hypertension at 4300 m is related to sympatho-adrenal activity. J Appl Physiol 76:1643-1650