Long-term results of autologous marrow transplantation for relapsed or refractory male or female germ cell tumors

Bone Marrow Transplantation

Volumn 21, Issue 6, 1998, Pages 569-576

  Mandanas, R A ^a,b   Saez, R A ^a   Epstein, R B ^a   Confer, D L ^a   Selby, G B ^a  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^b NONE   (United States)

Author keywords

Bone marrow transplantation; Cisplatin refractory; Germ cell tumors; Relapsed

Indexed keywords

CARBOPLATIN; CISPLATIN; CYCLOPHOSPHAMIDE; ETOPOSIDE; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; RECOMBINANT GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR;

ADOLESCENT; ADULT; ARTICLE; ASPERGILLOSIS; AUTOLOGOUS BONE MARROW TRANSPLANTATION; BLEEDING; CANCER CHEMOTHERAPY; CANCER SURVIVAL; CAUSE OF DEATH; CLINICAL ARTICLE; DYSGERMINOMA; FEMALE; GASTROINTESTINAL SYMPTOM; GERM CELL TUMOR; HEARING LOSS; HUMAN; INTERSTITIAL PNEUMONIA; LIVER TOXICITY; MALE; NEUROPATHY; OVARY TUMOR; PINEAL BODY TUMOR; PRIORITY JOURNAL; SEMINOMA; SURVIVAL RATE; TESTIS TUMOR;

EID: 0031907291     PISSN: 02683369     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bmt.1701132     Document Type: Article

References (26)

1. Williams SD, Loehrer PJ, Nichols CR, Einhorn LN. Chemotherapy of male and female germ cell tumors. Semin Oncol 1992; 19 (Suppl. 5): 19-23.
2. Loehrer PJ, Einhorn LH, Williams SD. VP-16 plus ifosfamide plus cisplatin as salvage therapy in refractory germ cell cancer. J Clin Oncol 1986; 4: 528-536.
3. Einhorn L. Salvage therapy for germ cell tumors. Semin Oncol 1994; 21 (Suppl. 7): 47-51.
4. Nichols CR, Tricot G, Williams SD et al. Dose-intensive chemotherapy in refractory germ cell cancer - a phase I/II trial of high-dose carboplatin and etoposide with autologous bone marrow transplantation. J Clin Oncol 1989; 7: 932-939.
5. Nichols CR, Anderson J, Lazarus HM et al. High-dose carboplatin and etoposide with autologous bone marrow transplantation in refractory germ cell cancer: an Eastern Cooperative Oncology Group protocol. J Clin Oncol 1992; 10: 558-563.
6. Broun ER, Nichols CR, Mandanas R et al. Dose escalation study of high-dose carboplatin and etoposide with autologous bone marrow support in patients with recurrent and refractory germ cell tumors. Bone Marrow Transplant 1995; 16: 353-358.
7. Broun ER, Nichols CR. Kneebone P et al. Long-term outcome of patient with relapsed and refractory germ cell tumors treated with high-dose chemotherapy and autologous bone marrow rescue. Ann Intern Med 1992; 117: 124-128.
8. Broun ER, Nichols CR, Tricot G et al. High-dose carboplatin/VP-16 plus ifosfamide with autologous bone marrow support in the treatment of refractory germ cell tumors. Bone Marrow Transplant 1991; 7: 53-56.
9. Droz JP, Pico JL, Ghosn M et al. Long-term survivors after salvage high-dose chemotherapy with bone marrow rescue in refractory germ cell cancer. Eur J Cancer 1991; 27: 831-835.
10. Beyer J, Kramar A, Mandanas R et al. High-dose chemotherapy as salvage treatment in germ cell tumors: a multivariate analysis of prognostic variables. J Clin Oncol 1996; 14: 2638-2645.
11. Birch R, Williams S, Cone A et al. Prognostic factors for unfavorable outcome in disseminated germ cell tumors. J Clin Oncol 1986; 4: 400-407.
12. Thomas ED, Storb R, Technique for human marrow grafting. Blood 1970; 36: 507-515.
13. Buckner CD, Clift RA, Sanders JE et al. Marrow harvesting from normal donors. Blood 1984; 64: 630-634.
14. Cantor AB. Extending SAS survival analysis techniques for medical research. SAS Institute: Cary, NC, 1997, pp 20, 59.
15. Motzer RJ, Gulati SC, Crown JP et al. High-dose chemotherapy and autologous bone marrow rescue for patients with refractory germ cell tumors. Early intervention is better tolerated. Cancer 1992; 69: 550-556.
16. Motzer RJ, Mazumdar M, Gulati SC et al. Phase II trial of high-dose carboplatin and etoposide with autologous bone marrow transplantation in first-line therapy for patients with poor risk germ cell tumors. J Natl Cancer Inst 1993; 85: 1828-1835.
17. Rodenhuis S, van der Wall E, ten Bokkel Huinink WW et al. Pilot study of a high-dose carboplatin-based strategy for relapsing or refractory germ cell cancer. Cancer Invest 1995; 13: 355-362.
18. Margolin K, Doroshow JH, Ahn C et al. Treatment of germ cell cancer with two cycles of high-dose ifosfamide, carboplatin, and etoposide with autologous stem-cell support. J Clin Oncol 1996; 14: 2631-2637.
19. Broun ER, Nichols CR, Turns M et al. Early salvage therapy for germ cell cancer using high dose chemotherapy with autologous bone marrow support. Cancer 1994; 73: 1716-1720.
20. Barnett MJ, Coppin CM, Murray N et al. High-dose chemotherapy and autologous bone marrow transplantation for patients with poor prognosis nonseminomatous germ cell tumours. Br J Cancer 1993; 68: 594-598.
21. Broun ER, Nichols CR, Einhorn LH, Tricot GJK. Salvage therapy with high-dose chemotherapy and autologous bone marrow support in the treatment of primary nonseminomatous mediastinal germ cell tumors. Cancer 1991; 68: 1513-1515.
22. Lotz J-P, Andre T, Donsimoni R et al. High-dose chemotherapy with ifosfamide, carboplatin, and etoposide combined with autologous bone marrow transplantation for the treatment of poor-prognosis germ cell tumors and metastatic trophoblastic disease in adults. Cancer 1995; 75: 874-885.
23. Motzer RJ, Bosl GJ. High-dose chemotherapy for resistant germ cell tumors: recent advances and future directions. J Natl Cancer Inst 1992; 84: 1703-1709.
24. Motzer RJ, Mazumdar M, Bosl GJ et al. High-dose carboplatin, etoposide, and cyclophosphamide for patients with refractory germ cell tumors: treatment results and prognostic factors for survival and toxicity. J Clin Oncol 1996, 14: 1098-1105.
25. Droz JP, Kramar A, Pico JL. Prediction of long-term response after high-dose chemotherapy with autologous hone marrow transplantation in the salvage treatment of non-seminomatous germ cell tumors. Eur J Cancer 1993; 29A: 818-821.
26. Droz J-P, Pico J-L, Kramar A. Role of autologous bone marrow transplantation in germ-cell cancer. Urol Clin N Am 1993; 20: 161-171.