Binding of phospholipid transfer protein (PLTP) to apolipoproteins A-I and A-II: Location of a PLTP binding domain in the amino terminal region of apoa-I

Journal of Lipid Research

Volumn 39, Issue 1, 1998, Pages 152-161

  Pussinen, Pirkko J ^a   Jauhiainen, Matti ^a   Metso, Jari ^a   Pyle, Louise E ^b   Marcel, Yves L ^c   Fidge, Noel H ^b   Ehnholm, Christian ^a  

^a NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^b BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

^c UNIVERSITY OF OTTAWA HEART INSTITUTE   (Canada)

Author keywords

ELISA; High density lipoproteins; Pig lipoproteins

Indexed keywords

APOLIPOPROTEIN A1; APOLIPOPROTEIN A2; PHOSPHOLIPID TRANSFER PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; MOLECULAR INTERACTION; PHOSPHOLIPID TRANSFER; PRIORITY JOURNAL; PROTEIN LIPID INTERACTION; PROTEIN PURIFICATION; SEQUENCE ANALYSIS;

ANTIBODIES; ANTIBODIES, MONOCLONAL; APOLIPOPROTEIN A-I; APOLIPOPROTEIN A-II; BINDING SITES; BINDING, COMPETITIVE; CARRIER PROTEINS; CHROMATOGRAPHY, AFFINITY; CYANOGEN BROMIDE; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; MEMBRANE PROTEINS; PEPTIDE FRAGMENTS; PHOSPHOLIPID TRANSFER PROTEINS; RECOMBINANT PROTEINS;

EID: 0031907176     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (64)

1. Castro, G. R., and C. J. Fielding. 1988. Early incorporation of cell-derived cholesterol into pre-β-migrating high-density lipoprotein. Biochemistry. 27: 25-29.
2. Jauhiainen, M., J. Metso, R. Pahlman, S. Blomqvist, A. van Tol, and C. Ehnholm. 1993. Human plasma phospholipid transfer protein causes high density lipoprotein conversion. J. Biol. Chem. 268: 4032-4036.
3. Tu, A-Y., H. I. Nishida, and T. Nishida. 1993. High density lipoprotein conversion mediated by human plasma phospholipid transfer protein. J. Biol. Chem. 268: 23098-23105.
4. von Eckardstein, A., M. Jauhiainen, Y. Huang, J. Metso, C. Langer, P. Pussinen, S. Wu, C. Ehnholm, and G. Assmann. 1996. Phospholipid transfer protein-mediated conversion of high density lipoprotein generates preβ1-HDL. Biochim. Biophys. Acta. 1301: 255-262.
5. Jiang, X-C., O. L. Francone, C. Bruce, R. Milne, J. Mar, A. Walsh, J. L. Breslow, and A. R. Tall. 1996. Increased preβ-high density lipoprotein, apolipoprotein A-I, and phospholipid in mice expressing the human phospholipid transfer protein and human apolipoprotein A-I transgenes. J. Clin. Invest. 96: 2373-2380.
6. Lagrost, L., A. Athias, P. Gambert, and C. Lallemant. 1994. Comparative study of phospholipid transfer activities by cholesteryl ester transfer protein and phospholipid transfer protein. J. Lipid Res. 35: 825-835.
7. Kostner, G. M., K. Oettl, M. Jauhiainen, C. Ehnholm, H. Esterbauer, and H. Dieplinger. 1995. Human plasma phospholipid transfer protein accelerates exchange/transfer of α-tocopherol between lipoproteins and cells. Biochem. J. 305: 659-667.
8. Tollefson, J. H., S. Ravnik, and J. J. Albers. 1988. Isolation and characterization of a phospholipid transfer protein (LTP-II) from human plasma. J. Lipid Res. 29: 1593-1602.
9. Mallov, M. J., A. Zoppo, A-Y. Tu, P. O'Connor, S. T. Kunitake, R. L. Hamilton, E. Robbins, C. J. Fielding, and J. P. Kane. 1994. A new metabolic disorder: phospholipid transfer protein deficiency. Clin. Res. 42: 85A.
10. Massey, J. B., D. Hickson-Bick, D. P. Via, A. M. Gotto, Jr., and H. J. Pownall. 1985. Fluorescence assay of the specificity of human plasma and bovine liver phospholipid transfer protein. Biochim. Biophys. Acta. 835: 124-131.
11. Huuskonen, J., V. M. Olkkonen, M. Jauhiainen, J. Metso, P. Somerharju, and C. Ehnholm. 1996. Acyl chain head-group specificity of human plasma phospholipid transfer protein. Biochim. Biophys. Acta. 712: 444-452.
12. Lusa, S., M. Jauhiainen, J. Metso, P. Somerharju, and C. Ehnholm. 1996. The mechanism of human plasma phospholipid transfer protein-induced enlargement of high-density lipoprotein particles: evidence for particle fusion. Biochem. J. 313: 275-282.
13. Pussinen, P. J., M. Jauhiainen, and C. Ehnholm. 1997. ApoA-II/apoA-I molar ratio in the HDL particle influences phospholipid transfer protein-mediated HDL interconversion. J. Lipid Res. 38: 12-21.
14. Speijer, H., J. E. M. Groener, E. van Ramshorst, and A. van Tol. 1991. Different locations of cholesteryl ester transfer protein and phospholipid transfer protein activities in plasma. Atherosclerosis. 90: 159-168.
15. Havel, R. J., H. A. Eder, and J. R. Bragdon. 1955. The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. J. Clin. Invest. 34: 1345-1353.
16. Scanu, A. 1966. Forms of human serum high density lipoprotein protein. J. Lipid Res. 7: 295-306.
17. Scanu, A., and C. Edelstein. 1971. Solubility in aqueous solutions of ethanol of small molecular weight peptides of the serum very low density and high density lipoproteins: relevance to the recovery problem during delipidation of serum lipoproteins. Anal. Biochem. 44: 576-588.
18. Scanu, A. M., C. T. Lim, and C. Edelstein. 1972. On the subunit structure of the protein of human serum high density lipoprotein. J. Biol. Chem. 247: 5850-5855.
19. Morrison, J. R., N. H. Fidge, and B. Grego. 1990. Studies on the formation, separation, and characterization of cyanogen bromide fragments of human A-I apolipoprotein. Anal. Biochem. 186: 145-152.
20. Avrameas, S., and T. Ternynck. 1971. Peroxidase labelled antibody and Fab conjugates with enhanced intracellular penetration. Immunochemistry. 8: 1175-1179.
21. Pyle, L. E., W. H. Sawyer, Y. Fujiwara, A. Mitchell, and N. H. Fidge. 1996. Structural and functional properties of full-length and truncated human proapolipoprotein A-I expressed in Escherichia coli. Biochemistry. 35: 12046-12052.
22. Pussinen, P., M. Jauhiainen, J. Metso, J. Tyynelä, and C. Ehnholm. 1995. Pig plasma phospholipid transfer protein facilitates HDL interconversion. J. Lipid Res. 36: 975-985.
23. Lowry, O. H., N. J. Rosebrough, A. L. Farr, and R. J. Randall. 1951. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193: 265-275.
24. Riepponen, P., J. Marniemi, and T. Rautaoja. 1987. Immunoturbidimetric assays of apolipoproteins A-I and B in serum. Scand. J. Clin. Lab. Invest. 47: 739-745.
25. Groener, J. E. M., R. W. Pelton, and G. M. Kostner. 1986. Improved estimation of cholesteryl ester transfer/exchange activity in serum or plasma. Clin. Chem. 32: 283-286.
26. 14C]phosphatidylcholine between liposomes and human plasma high density lipoprotein. Partial purification of a transfer-stimulating plasma factor using a rapid transfer assay. Biochim. Biophys. Acta. 712: 444-452.
27. Laemmli, U. K. 1979. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227: 680-685.
28. Towbin, H., T. Staehelin, and J. Gordon. 1979. Electrophoretic transfer of protein from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. USA. 76: 4350-4357.
29. Fidge, N., J. Morrison, T. Nugent, and M. Tozuka. 1989. Monoclonal antibodies to human A-I apolipoprotein and characterisation of cyanogen bromide fragments of apoA-I. Biochim. Biophys. Acta. 1003: 84-90.
30. Fielding, P. E., M. Kawano, A. L. Catapano, A. Zoppo, S. Marcovina, and C. J. Fielding. 1994. Unique epitope of apolipoprotein A-I expressed in pre-β-1 high-density lipoprotein and its role in the catalyzed efflux of cellular cholesterol. Biochemistry. 33: 6981-6985.
31. Marcel, Y. L., E. Rassart, L. Brissette, and R. W. Milne. 1992. Immunochemical studies of apolipoprotein structure and function. In Structure and Function of Apolipoproteins. M. Rosseneu, editor. CRC Press, Inc., Boca Raton, Fl. 363-399.
32. Cheung, M. C., and J. J. Albers. 1982. Distribution of high density lipoprotein particles with different apolipoprotein composition: particles with A-I and A-II and particles with A-I but not A-II. J. Lipid Res. 23: 747-753.
33. Ikewaki, K., L. A. Zech, M. Kindt, H. B. Brewer, Jr., and D. J. Rader. 1995. Apolipoprotein A-II production rate is a major factor regulating the distribution of apolipoprotein A-I among HDL subclasses LpA-I and LpA-I:A-II in normolipidemic humans. Arterioscler. Thromb. Vasc. Biol. 15: 306-312.
34. Barbaras, R., P. Puchois, J. C. Fruchart, and G. Ailhaud. 1987. Cholesterol efflux from cultured adipose cells is mediated by LpA-I particles but not by LpA-I:A-II particles. Biochem. Biophys. Res. Commun. 142: 63-69.
35. Puchois, P., A. Kandoussi, P. Fievet, J. L. Fourrier, M. Bertrand, E. Koren, and J. C. Fruchart. 1987. Apolipoprotein A-I-containing lipoproteins in coronary artery disease. Atherosclerosis. 68: 35-40.
36. Barkia, A., P. Puchois, N. Ghalim, G. Torpier, R. Barbaras, G. Ailhaud, and J. C. Fruchart. 1991. Differential rate of apolipoprotein A-I-containing particles in cholesterol efflux from adipose tissue. Atherosclerosis. 87: 135-146.
37. Lagrost, L., C. Dangremont, A. Athias, C. de Geitere, J-C. Fruchart, C. Lallemant, P. Gambert, and G. Castro. 1995. Modulation of cholesterol efflux from Fu5AH hepatoma cells by the apolipoprotein content of high density lipoprotein particles. J. Biol. Chem. 270: 13004-13009.
38. Huang, Y., A. von Eckardstein, S. Wu, and G. Assmann. 1995. Cholesterol efflux, cholesterol esterification, and cholesteryl ester transfer by LpA-I and LpA-I/A-II in native plasma. Arterioscler. Thromb. Vasc. Biol. 15: 1412-1418.
39. Rubin, E. M., B. Y. Ishida, S. M. Clift, and R. M. Krauss. 1991. Expression of human apolipoprotein A-I in transgenic mice results in reduced plasma levels of murine apolipoprotein A-I and appearance of two new high density lipoprotein size subclasses. Proc. Natl. Acad. Sci. USA. 88: 434-438.
40. Warden, C. H., C. C. Hedrick, J-H. Qiao, L. W. Castellani, and A. J. Lusis. 1993. Atherosclerosis in transgenic mice overexpressing apolipoprotein A-II. Science. 261: 469-472.
41. Yamazaki, S., T. Mitsunaga, Y. Furukawa, and T. Nishida. 1983. Interaction of lecithin:cholesterol acyltransferase with human plasma lipoproteins and with lecithin-cholesterol vesicles. J. Biol. Chem. 258: 5847-5853.
42. Cheung, M. C., A. C. Wolf, K. D. Lum, J. H. Tollefson, and J. J. Albers. 1986. Distribution and localization of lecithin: cholesterol acyltransferase and cholesteryl ester transfer activity in A-I-containing lipoproteins. J. Lipid Res. 27: 1135-1144.
43. Nishida, H. I., H. Kato, and T. Nishida. 1990. Affinity of lipid transfer protein for lipid and lipoprotein particles as influenced by lecithin:cholesterol acyltransferase. J. Biol. Chem. 265: 4876-4883.
44. 2 subfractions with hepatic lipase. J. Lipid Res. 33: 1269-1279.
45. Mowri, H-O., J. R. Patsch, A. Ritsch, B. Foger, S. Brown, and W. Patsch. 1994. High density lipoproteins with differing apolipoproteins: relationships to postprandial lipemia, cholesteryl ester transfer protein, and activities of lipoprotein lipase, hepatic lipase, and lecithin:cholesterol acyltransferase. J. Lipid Res. 35: 291-300.
46. Francone, O. L., A. Gurakar, and C. J. Fielding. 1989. Distribution and functions of lecithin:cholesterol acyltransferase and cholesteryl ester transfer protein in plasma lipoproteins. Evidence for a functional unit containing these activities together with apolipoprotein A-I and D that catalyzes the esterification and transfer of cell-derived cholesterol. J. Biol. Chem. 264: 7066-7072.
47. Francone, O. L., E. L. Gong, D. S. Ng, C. J. Fielding, and E. M. Rubin. 1995. Expression of human lecithin:cholesterol acyltransferase in transgenic mice. Effect of human apolipoprotein A-I and human apolipoprotein A-II on plasma lipoprotein cholesterol metabolism. J. Clin. Invest. 96: 1440-1448.
48. Hayek, T., T. Chajek-Shaul, A. Walsh, L. B. Agellon, P. Moulin, A. R. Tall, and J. L. Breslow. 1992. An interaction between the human cholesteryl ester transfer protein (CETP) and apolipoprotein A-I genes in transgenic mice results in a profound CETP-mediated depression of high density lipoprotein cholesterol levels. J. Clin. Invest. 90: 505-510.
49. Albers, J. J., G. Wolfbauer, M. C. Cheung, J. R. Day, A. F. T. Ching, and A-Y. Tu. 1995. Functional expression of human and mouse plasma phospholipid transfer protein: effect of recombinant and plasma PLTP on HDL subspecies. Biochim. Biophys. Acta. 1258: 27-34.
50. Palgunachari, M. N., V. K. Mishra, S. Lund-Katz, M. C. Phillips, S. O. Adeyeye, S. Alluri, G. M. Anantharamaiah, and J. P. Segrest. 1996. Only the two end helixes of eight tandem amphipathic helical domains of human apoA-I have significant lipid affinity. Arterioscler. Thromb. Vasc. Biol. 16: 328-338.
51. Sviridov, D., L. E. Pyle, and N. Fidge. 1996. Efflux of cellular cholesterol and phospholipid to apolipoprotein A-I mutants. J. Biol. Chem. 271: 33277-33283.
52. Allan, C. M., N. H. Fidge, and J. Kanellos. 1992. Antibodies to the carboxyl terminus of human apolipoprotein A-I. J. Biol. Chem. 267: 13257-13261.
53. Collet, X., B. Perret, G. Simard, E. Raffai, and Y. L. Marcel. 1991. Differential effects of cholesterol in the immunoreactivities and conformation of apolipoprotein A-I in high density lipoprotein. J. Biol. Chem. 266: 9145-9152.
54. Frank, P. G., J. Bergeron, F. Emmanuel, J-P. Lavigne, D. L. Sparks, P. Denefle, E. Rassart, and Y. L. Marcel. 1997. Deletion of central α-helices in human apolipoprotein A-I: effect on phospholipid association. Biochemistry. 36: 1798-1806.
55. Nishida, H. I., and T. Nishida. 1997. Phospholipid transfer protein mediates transfer of not only phosphatidylcholine but also cholesterol from phosphatidylcholine-cholesterol vesicles to high density lipoproteins. J. Biol. Chem. 272: 6959-6964.
56. Guyard-Dangremont, V., L. Lagrost, and P. Gambert. 1994. Comparative effects of purified apolipoproteins A-I, A-II, and A-IV on cholesteryl ester transfer protein activity. J. Lipid Res. 35: 982-992.
57. Bruce, C., W. S. Davidson, P. Kussie, S. Lund-Katz, M. C. Phillips, R. Ghosh, and A. R. Tall. 1995. Molecular determinants of plasma cholesteryl ester transfer protein binding to high density lipoproteins. J. Biol. Chem. 270: 11532-11542.
58. Massamiri, T., P. S. Tobias, and L. K. Curtiss. 1997. Structural determinants for the interaction of lipopolysaccharide binding protein with purified high density lipoproteins: role of apolipoprotein A-I. J. Lipid Res. 38: 516-525.
59. Day, J. R., J. J. Albers, C. E. Lofton-Day, T. L. Gilbert, A. F. T. Ching, F. J. Grant, P. J. O'Hara, S. M. Marcovina, and J. L. Adolphson. 1994. Complete cDNA encoding human phospholipid transfer protein from human endothelial cells. J. Biol. Chem. 269: 9388-9391.
60. Jonas, A., K. E. Kezdy, and J. H. Wald. 1989. Defined apolipoprotein A-I conformations in reconstituted high density lipoprotein discs. J. Biol. Chem. 264: 4818-4824.
61. Brasseur, R., J. De Meutter, B. Vanloo, E. Goormaghtigh, J. M. Ruysschaert, and M. Rosseneu. 1990. Mode of assembly of amphipathic α-helical segments in model high density lipoproteins. Biochim. Biophys. Acta. 1043: 245-252.
62. Jonas, A., A. Steinmetz, and L. Churgay. 1993. The number of amphipathic a-helical segments of apolipoproteins A-I, E, and A-IV determines the size and functional properties of their reconstituted lipoprotein particles. J. Biol. Chem. 268: 1596-1602.
63. Talussot, P., and G. Ponsin. 1991. Cholesterol-induced alteration of apolipoprotein A-I conformation in reassembled high density lipoprotein. Biochimie. 73: 1173-1178.
64. Rosseneu, M., P. Van Tornout, M-J. Lievens, and G. Assmann. 1981. Displacement of the human apoprotein A-I by the human apoprotein A-II from complexes of (apoprotein A-I)-phosphatidylcholine-cholesterol. Eur. J. Biochem. 117: 347-352.