Therapeutic effects of an injectable new quinolone, pazufloxacin, against polymicrobial infections in the uterine endometritis model

Chemotherapy

Volumn 44, Issue 2, 1998, Pages 99-102

  Mikamo, Hiroshige ^a   Kawazoe, Kyoko ^a   Sato, Yasumasa ^a   Tamaya, Teruhiko ^a  

^a GIFU UNIVERSITY   (Japan)

Author keywords

Ceftazidime; Experimental model; Pazufloxacin (T 3762); Uterine endometritis

Indexed keywords

CEFTAZIDIME; PAZUFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT;

ADNEXITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL COUNT; BACTERIAL INFECTION; BACTEROIDES FRAGILIS; CONTROLLED STUDY; DRUG EFFICACY; DRUG FORMULATION; ENDOMETRITIS; ESCHERICHIA COLI; FEMALE; FEMALE GENITAL TRACT INFECTION; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANTI-INFECTIVE AGENTS; BACTEROIDES FRAGILIS; BACTEROIDES INFECTIONS; CEFTAZIDIME; CEPHALOSPORINS; COLONY COUNT, MICROBIAL; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOMETRITIS; ESCHERICHIA COLI INFECTIONS; FEMALE; FLUOROQUINOLONES; GENITAL DISEASES, FEMALE; INJECTIONS, INTRAVENOUS; MICROBIAL SENSITIVITY TESTS; OXAZINES; RATS; RATS, SPRAGUE-DAWLEY; SPECIES SPECIFICITY;

EID: 0031906794     PISSN: 00093157     EISSN: None     Source Type: Journal    
DOI: 10.1159/000007099     Document Type: Article

References (5)

1. Wolfson JS, Hooper DC: The fluoroquinolones: Clinical and laboratory considerations. Clin Microbiol Newslett 1992;14:1-7.
2. Muratani T, Inoue M, Mitsuhashi S: In vitro activity of T-3761, a new fluoroquinolone. Antimicrob Agents Chemother 1992;36:2293-2303.
3. Fukuoka Y, Ikeda Y, Yamashiro Y, Takahata M, Todo T, Narita H: In vitro and in vivo antibacterial activities of T-3761, a new quinolone derivative. Antimicrob Agents Chemother 1993;37:384-392.
4. Mikamo H, Ito K, Izumi K, Kawazoe K, Yamada Y, Tamaya T: Fundamental and clinical studies of cefluprenam (CFLP) in the fields of obstetrics and gynecology. Jpn J Chemother 1995;43(S-4):204-209.
5. Fukuoka Y, Ikeda Y, Noumi S, Minami S, Hayakawa H: T-3761, a novel pyridonecarboxylic acid, its pharmacokinetics and safety in experimental animals (abstract 389). 30th Intersci Conf Antimicrob Agents Chemother.