Chronic exposure to aluminum impairs neuronal glutamate-nitric oxide- cyclic GMP pathway

Journal of Neurochemistry

Volumn 70, Issue 4, 1998, Pages 1609-1614

  Cucarella, Carmen ^a   Montoliu, Carmina ^a   Hermenegildo, Carlos ^a   Sáez, Rosana ^a   Manzo, Luigi ^b   Miñana, María Dolores ^a   Felipo, Vicente ^a,c  

^a CENTRO DE INVESTIGACIÓN PRÍNCIPE FELIPE   (Spain)

^b Toxicology Research Centre   (Italy)

^c Laboratorio de Neurobiologia de Prince Felipe Research Centre   (Spain)

Author keywords

Aluminum; Cyclic GMP; Glutamate; Neurotoxicity; Nitric oxide synthase; NMDA receptors

Indexed keywords

ALUMINUM SULFATE; CYCLIC GMP; GLUTAMIC ACID; GUANYLATE CYCLASE; N ACETYL S NITROSOPENICILLAMINE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CEREBELLUM; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; LONG TERM EXPOSURE; NERVE CELL CULTURE; NEUROTOXICITY; NONHUMAN; PRENATAL EXPOSURE; PRIORITY JOURNAL; RAT;

EID: 0031906589     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1998.70041609.x     Document Type: Article

References (28)

1. Alfrey A. C., Legendre G. R., and Kaehny W. D. (1976) The dialysis encephalopathy syndrome. Possible aluminum intoxication. N. Engl. J. Med. 294, 184-188.
2. Anwyl R. (1989) Protein kinase C and long-term potentiation in the hippocampus. Trends Pharmacol. Sci. 10, 236-239.
3. Boegman R. J. and Bates L. A. (1984) Neurotoxicity of aluminum. Can. J. Physiol. Pharmacol. 62, 1010-1014.
4. Boulton C. L., Southam E., and Garthwaite J. (1995) Nitric oxide-dependent long-term potentiation is blocked by a specific inhibitor of soluble guanylyl cyclase. Neuroscience 69, 699-703.
5. Farnell B. J., Crapper-McLachlan D. R., Baimbridge K., DeBoni U., Wong L., and Wood P. L. (1985) Calcium metabolism in aluminum encephalopathy. Exp. Neurol. 88, 68-83.
6. Felipo V., Miñana M. D., and Grisolía S. (1993) Inhibitors of protein kinase C prevent the toxicity of glutamate in primary neuronal cultures. Brain Res. 604, 192-196.
7. Gadjusek C. D. and Salazar A. M. (1982) Amyotrophic lateral sclerosis and parkinsonian syndromes in high incidence among the Avyu and Japoi people of West New Guinea. Neurology 32, 107.
8. Gonda Z. and Lehotzky K. (1996) Effect of prenatal aluminium lactate exposure on conditioned taste aversion and passive avoidance task in the rat. J. Appl. Toxicol. 16, 529-532.
9. Harrington C. R., Wischik C. M., McArthur F. K., Taylor G. A., Edwardson J. A., and Candy J. M. (1994) Alzheimer's-disease-like changes in tau protein processing : association with aluminium accumulation in brain of renal dialysis patients. Lancet 343, 993.
10. Hawkins R. D. (1996) NO honey, I don't remember. Neuron 16, 465-467.
11. Johnson G. V. W. and Jope R. S. (1988) Phosphorylation of rat brain cytoskeletal proteins is increased after orally administered aluminum. Brain Res. 456, 95-103.
12. Jope R. S. and Johnson G. V. W. (1992) Neurotoxic effects of dietary aluminium. Ciba Found. Symp. 169, 254-267.
13. Kiedrowski L., Costa E., and Wroblewski J. T. (1992) Glutamate receptor agonists stimulate nitric oxide synthase in primary cultures of cerebellar granule cells. J. Neurochem. 58, 335-341.
14. Marcaida G., Miñana M. D., Burgal M., Grisolía S., and Felipo V. (1995) Ammonia prevents activation of NMDA receptors by glutamate in rat cerebellar neuronal cultures. Eur. J. Neurosci. 7, 2389-2396.
15. Perl P. D. and Brody A. K. (1980) X-ray spectrometric evidence of aluminum accumulation in neurofibrillary tangle-bearing neurons. Science 208, 297-299.
16. Perl D. P., Gadjusek C. D., Garruto R. M., Yanagihara R. T., and Gibbs C. J. Jr. (1982) Intraneuronal aluminum accumulation in amyotrophic lateral sclerosis and parkinsonism dementia. Science 217, 1053-1055.
17. Platt B. and Reyman K. G. (1996) Inhibition of TEA-induced LTP by aluminum. Exp. Neurol. 141, 240-247.
18. Platt B., Haas H., and Büsselberg D. (1994) Aluminium reduces glutamate-activated currents of rat hippocampal neurones. Neuroreport 5, 2329-2332.
19. Platt B., Carpenter D. O., Büsselberg D., Reyman K. G., and Riedel G. (1995) Aluminum impairs hippocampal long-term potentiation in rats in vitro and in vivo. Exp. Neurol. 134, 73-86.
20. Provan S. D. and Yokel R. A. (1992) Aluminum inhibits glutamate release from transverse rat hippocampal slices: role of G proteins, Ca channels and protein kinase C. Neurotoxicology 13, 413-420.
21. Richardt G., Federolf G., and Habermann E. (1985) The interaction of aluminum and other metal ions with calcium-calmodulin-dependent phosphodiesterase. Arch. Toxicol. 57, 257-259.
22. Siegel N. and Haug A. (1983) Aluminum interaction with calmodulin. Evidence for altered structure and function from optical and enzymatic studies. Biochim. Biophys. Acta 744, 36-45.
23. Siegel N., Coughlin R., and Haug A. (1983) A thermodynamic and electron paramagnetic resonance study of structural changes in calmodulin induced by aluminum binding. Biochem. Biophys. Res. Commun. 115, 512-517.
24. Suarez-Fernandez M. B., Torreblanca-Pacios A., Goenaga-Infanta H., Soldado A. B., Sanz-Medel A., Vega J. A., and Novelli A. (1996) Aluminium accumulation and toxicity in cultured neurons and astrocytes, in Metal Ions in Biology and Medicine, Vol. 4 (Collery Ph., Corbella J., Domingo J. L., Etienne J. C., and Llobet J. M., eds), pp. 284-286. John Libbey, Paris.
25. Suhayda C. G. and Haug A. (1984) Organic acids prevent aluminum-induced conformational changes in calmodulin. Biochem. Biophys. Res. Commun. 119, 376-381.
26. Vig P. J., Nath R., and Desaiah D. (1989) Metal inhibition of calmodulin activity in monkey brain. J. Appl. Toxicol. 9, 313-316.
27. Weis C. and Haug A. (1987) Aluminum-induced conformational changes in calmodulin alter the dynamics of interaction with melittin. Arch. Biochem. Biophys. 254, 304-312.
28. 2+ ion binding to methionine and tyrosine spin-labeled bovine brain calmodulin. J. Inorg. Biochem. 41, 283-291.