Enhancement of antibody-dependent cellular cytotoxicity of neonatal cells by interleukin-2 (IL-2) and IL-12

Clinical and Diagnostic Laboratory Immunology

Volumn 5, Issue 1, 1998, Pages 98-104

  Nguyen, Quoc H ^a   Roberts, Robert L ^a   Ank, Bonnie J ^a   Lin, Syh Jae ^a,b   Lau, Casey K ^a   Stiehm, E Richard ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CHANG GUNG CHILDREN S HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 12; INTERLEUKIN 2;

ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY; ARTICLE; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; INFECTION RISK; INFECTION SENSITIVITY; MONONUCLEAR CELL; NATURAL KILLER CELL; PRIORITY JOURNAL;

EID: 0031906088     PISSN: 1071412X     EISSN: None     Source Type: Journal    
DOI: 10.1128/cdli.5.1.98-104.1998     Document Type: Article

References (52)

1. lek modulation in CD3-or CD2-activated T-cells from neonates. Pediatr. Res. 37:64-68.
2. Armant, M., G. Delespesse, and M. Sarfati. 1995. IL-2 and IL-7 but not IL-12 protect natural killer cells from death by apoptosis and up-regulate bcl-2 expression. Immunology 85:331-337.
3. Baum, L. L., K. J. Cassutt, K. Knigge, R. Khattri, J. Margolick, C. Rinaldo, C. A. Kleeberger, P. Nishanian, D. R. Henrard, and J. Phair. 1996. HIV-1 gp120-specific antibody-dependent cell-mediated cytotoxicity correlates with rate of disease progression. J. Immunol. 157:2168-2173.
4. Bonnema, J. D., K. A. Rivlin, A. T. Ting, R. A. Schoon, R. T. Abraham, and P. J. Leibson. 1994. Cytokine-enhanced NK cell-mediated cytotoxicity: positive modulatory effects of IL-2 and IL-12 on stimulus dependent granule exocytosis. J. Immunol. 152:2098-2104.
5. Chchimi, J., S. E. Starr, I. Frank, M. Rengaraju, S. J. Jackson, C. Lianes, M. Kobayashi, B. Perussia, D. Young, E. Nickbarg, S. F. Wolf, and G. Trinchieri. 1992. Natural killer (NK) cell stimulatory factor increases the cytotoxic activity of NK cells from both healthy donors and human immunodeficiency virus-infected patients. J. Exp. Med. 175:789-796.
6. Chehimi, J., N. M. Valiante, A. D'Andrea, M. Regaraju, Z. Rosado, M. Kobayashi, B. Perussia, S. F. Wolf, S. E. Starr, and G. Trinchieri. 1993. Enhancing effect of natural killer cell stimulatory factor (NKSF/interleukin-12) on cell-mediated cytotoxicity against tumor-derived and virus-infected cells. J. Immunol. 23:1825 -1830.
7. Clerici, M., A. Sarin, R. L. Coffman, T. A. Wynn, S. P. Blatt, C. W. Hendrix, S. F. Wolf, G. M. Shearer, and P. A. Henkart. 1994. Type 1/type 2 cytokinc modulation of T-cell programmed death as a model for human Immunodeficiency virus pathogenesis. Proc. Natl. Acad. Sci. USA 91:11811-11815.
8. Cummins, L. M., K. J. Weinhold, T. J. Matthews, A. J. Langlois, C. F. Perno, R. M. Condie, and J. Allain. 1991. Preparation and characterization of an intravenous solution of IgG from human immunodeficiency virus-seropositive donors. Blood 77:1111 -1117.
9. DeBlaker-Hohe, D. F., A. Yamauchi, and C. R. Yu. 1995. IL-12 synergizes with IL-2 to induce lymphokine-activated cytotoxicity and perform and granzyme gene expression in fresh NK cells. Cell. Immunol. 165:33-43.
10. Gaddy, J., G. Risdon, and H. Broxmeyer. 1995. Cord blood natural killer cells are functionally and phenotypically immature but readily respond to interleukin-2 and interleukin-12. J. Interferon Cytokine Res. 15:527-536.
11. Hassan, J., and R. J. Reen. 1996. Reduced primary-antigen specific T-cell precursor frequencies in neonates is associated with deficient interleukin-2 production. Immunology 87:604-608.
12. Henney, C. S., K. Kuribayashi, D. E. Kern, and S. Gillis. 1981. Interleukin-2 augments natural killer activity. Nature 291:335-338.
13. Jacobson, E. L., F. Pilaro, and K. A. Smith. 1996. Rational interleukin 2 therapy for HIV positive individuals: daily low doses enhance immune function without toxicity. Proc. Natl. Acad. Sci. USA 93:10405-10410.
14. Jenkins, M., J. Mills, and S. Kohl. 1993. Natural killer cytotoxicity and antibody dependent cellular cytotoxicity or human immunodeficiency virusinfected cells by leukocytes from human neonates and adults. Pediatr. Res. 33:469-474.
15. Jewett, A., and B. Bonavida. 1994. Activation of human immature natural killer cell subset by IL-12 and its regulation by endogenous TNF-α and IFN-γ secretion. Cell. Immunol. 154:273-286.
16. Kohl, S., M. Sigaroudinia, E. D. Charlebois, and M. A. Jacobson. 1996. Interleukin-12 administered in vivo decreases human NK cell cytotoxicity and antibody dependent cytotoxicity to human immunodeficiency virus-in-fected cells. J. Infect. Dis. 174:1105-1108.
17. Kohl, S., M. S. West, and L. S. Loo. 1988. Defects in interlcukin-2 stimulation of neonatal natural killer cytotoxicity to herpes simplex virus-infected cells. J. Pediatr. 112:976-981.
18. Landers, D. V., J. P. Smith, C. K. Walker, T. Milam, L. Sanchez-Pescador, and S. Kohl. 1994. Human fetal antibody-dependent cellular cytotoxicity to herpes simplex virus-infected cells. Pediatr. Res. 35:289-292.
19. Lau, A. S., M. Sigaroudinia, M. C. Yeung, and S. Kohl. 1995. Interleukin-12 induces interferon-γ expression and natural killer cytotoxicity in cord blood mononuclear cells. Pediatr. Res. 39:150-155.
20. Lee, S. M., Y. Suen, L. Chang, V. Burner, J. Quian, J. Indes, E. Knoppel, C. van de Ven, and M. S. Cairo. 1996. Decreased interleukin-12 (IL-12) from activated cord versus adult peripheral blood mononuclear cells and upregulation of interferon-γ, natural killer, and lymphokine-activated killer activity by IL-12 in cord blood mononuclear cells. Blood 88:945-954.
21. Leibson, P. J., M. H. Laszlo, G. S. Douvas, and A. R. Hayward. 1986. Impaired neonatal natural killer-cell activity to herpes simplex virus: decreased inhibition of viral replication and altered response to lymphokines. J. Clin. Immunol. 6:216-224.
22. Lewis, D. B., C. C. Yu, J. Meyer, B. K. English, S. J. Kahn, and C. B. Wilson. 1991. Cellular and molecular mechanisms for reduced interleukin-4 and interteron-γ production by neonatal T-cells. J. Clin. Invest. 87:194-202.
23. +) subjects: enhancement with interlcukin-2 (IL-2), IL-12, and IL-15. Clin. Immunol. Immunopathol. 82:163-173.
24. Lubens, R. G., S. E. Gard, M. S. Warner, and E. R. Stichm. 1982. Lectindependent T-lymphocyte and natural killer cytotoxic deficiencies in human newborns. Cell. Immunol. 74:40-53.
25. Merrill, J. D., M. Sigaroudinia, and S. Kohl. 1996. Characterization of natural killer and antibody-dependent cellular cytotoxicity of preterm infants against human immunodeficiency virus-infected cells. Pediatr. Res. 40:498-503.
26. Miller, J. S., S. Klingsporn, J. Lund, E. H. Perry, C. Verfaillie, and P. McClave. 1994. Large scale ex vivo expansion and activation of human natural killer cells for autologous therapy. Bone Marrow Transplant. 14:555-562.
27. Milosevits, J., E. Pocsik, B. Schimdt, P. Remenyi, Z. Intodi, M. Reti, A. Batai, P. Illes, R. Mihhalik, G. G. Petranyi, and K. Paloczi. 1995. Immunotypic and functional characteristics of haemopoietic cells from human cord blood. Scand. J. Immunol. 42:493-500.
28. Murphy, W. J., C. W. Reynolds, P. Tiberghien, and D. L. Longo. 1993. Natural killer cells and bone marrow transplantation. J. Natl. Cancer Inst. 85:1475-1482.
29. Naume, B., M. Gately, and T. Espevik. 1992. A comparative study of IL-12 (cytotoxic lymphocyte maturation factor)-, IL-2-and IL-7-induced effects on immunomagnetically purified CD56 NK cells. J. Immunol. 148:2429-2436.
30. Nelson, D. L., C. C. Kurman, M. E. Fritz, B. Boutin, and L. A. Rubin. 1986. The production of soluble and cellular interleukin-2 receptors by cord blood mononuclear cells following in vitro activation. Pediatr. Res. 20:136-139.
31. Ogata, K., H. Tamua, N. Yokose, E. An, K. Dan, H. Hamaguchi. H. Sakamaki, Y. Onozawa, S. C. Clark, and T. Nomura. 1995. Eflects of interleukin-12 on natural killer cell cytotoxicity and the production of interferongamma and tumor necrosis factor-alpha in patients with myelodysplastic syndromes. Br. J. Haematol. 90:15-21.
32. Osugi, Y., J. Hara, H. Kurahashi, N. Sakata, M. Inoue, K. Yumura-Yagi, K. Kawa-Ha, S. Okada, and A. Tawa. 1995. Age-related changes in surface antigens on peripheral lymphocytes of healthy children. Clin. Exp. Immunol. 100:543-548.
33. Philips, J. H., T. Hori, A. Nagler, N. Bhat, H. Spits, and L. L. Lanier. 1992. Ontogeny of human natural killer (NK) cells: fetal NK cells mediate cytolytic function and express cytoplasmic CD3 epsilon and gamma proteins. J. Exp. Med. 175:1055-1066.
34. Philips, J. H., and L. L. Lanier. 1986. Dissection of the lymphokine-activated killer phenomenon: relative contribution of peripheral blood natural killer cells and T-lymphocyte cytolysis. J. Exp. Med. 164:814.
35. Rosenberg, S. A., M. T. Lotze, and L. M. Muul. 1987. A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukin-2 or high dose interleukin-2 alone. N. Engl. J. Med. 316:889-897.
36. Sahin, U., S. Kraft-Bauer, S. Ohnesorge, M. Pfreundschuh, and C. Renner. 1996. Interleukin-12 increases bispecific-antibody-mediated natural killer cell cytotoxicity against human tumors. Cancer Immunol. lmmunother. 42:9-14.
37. Saito, 7., T. Morii, 11. Umekage, K. Makita, K. Nishikawa, N. Narita, M. Ichijo, H. Morikawa, N. Ishii, M. Nakamura, and K. Sugamura. 1996 Expression of the interleukin-2 receptor γ chain on cord blood mononuclear cells. Blood 87:3344-3350.
38. + and Leu-11 cell populations in cord blood and adult peripheral blood. J. Immunol. 135:2341-2356.
39. Smith, K. A. 1993. Lowest dose interleukin-2 immunotherapy. Blood 81: 1414-1423.
40. Soiffer, R. J., C. Murray, and K. Cochran. 1992. Clinical and immunologic effects of prolonged infusion of low-dose recombinant interleukin-2 after autologous and T-cell-depleted allogenic bone marrow transplantation. Blood 79:517-526.
41. Soiffer, R. J., M. J. Robertson, C. Murray, K. Cochran, and J. Ritz. 1993 Interleukin-12 augments cytolytic activity of peripheral blood lymphocytes from patients with hematologie and solid malignancies. Blood 82:2790-2796.
42. Stiehm, E. R., R. L. Roberts, B. J. Ank, S. Plaeger-Marshall, N. Salman, L. Shen, and M. Fanger. 1994. Comparison of cytotoxic properties of neonatal and adult neutrophils and monocytes and enhancement by cytokines. Clin. Diagn. Lab. Immunol. 1:342-347.
43. Takeshita, T., H. Asao, N. Ishii, S. Kumaki, N. Tanaka, H. Munakata, and K. Sugamura. 1992. Cloning of the gamma-chain of the human IL-2 receptor. Science 257:379.
44. Takeshita, T., K. Ohtani, H. Asao, S. Kumaki, M. Nakamura, and K. Sugamura. 1992. An associated molecule. p64, with IL-2 receptor beta chain. Its possible involvement in the formation of the functional intermediate affinity IL-2 receptor complex. J. Immunol. 148:2154-2158.
45. Trinchieri, G., M. Matsumoto-Kobayashi, S. Clark, J. Seehra, L. London, and B. Perussia. 1994. Response of resting human peripheral blood natural killer cells to interleukin-2. J. Exp. Med. 160:1147-1153.
46. Ueno, Y., T. Miyawaki, H. Seki, A. Matsuda, K. Taga, H. Sato, and N. Taniguchi. 1985. Differential effects of human interferon-gamma and interleukin-2 on natural killer cell activity of peripheral blood in early human development. J. Immunol. 135:180-184.
47. Watson, W., K. Oen, R. Ramdahin, and C. Harman. 1991. Immunoglobulin and cytokine production by neonatal lymphocytes. Clin. Exp. Immunol. 83: 169-174.
48. Wilson, C., J. Wetsall, L. Johnston, D. Lewis, S. Dower, and A. Alpert. 1986. Decreased production of interferon-γ by human neonatal cells. J. Clin. Invest. 77:860-867.
49. Wilson, C. B., D. B. Lewis, and L. A. Penix. 1996. The physiologic immunodeficiency of immaturity, p. 253-295. In E. R. Stiehm (ed.), Immunologic disorders in infants and children, 4th ed. The W. B. Saunders Co., Philadelphia. Pa.
50. Yabuhara, A., H. Kawai, and A. Komiyama. 1990. Development of natural killer cytotoxicity during childhood: marked increases in number of natural killer cells with adequate cytotoxic abilities during infancy to early childhood. Pediatr. Res. 28:316-322.
51. Ye, J., J. R. Ortaldo, K. Conion, R. Winkler-Pickett, and H. A. Young. 1995 Cellular and molecular mechanisms of IFN-γ production induced by IL-2 and IL-12 in a human NK cell line. J. Leukocyte Biol. 58:225-233.
52. Zola, H., M. Fuseo, H. Weedon, P. J. Macardle, J. Ridings, and D. M. Robertson. 1996. Reduced expression of the interleukin-2 receptor γ chain on cord blood lymphocytes: relationship to functional immaturity of the neonatal immune response. Immunology 87:86-91.