Identification of a functional glucocorticoid response element in the CYP3A1/IGC2 gene

DNA and Cell Biology

Volumn 17, Issue 1, 1998, Pages 39-49

  Pereira, Teresa M ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

16ALPHA CYANOPREGNENOLONE; CYTOCHROME P450; DEXAMETHASONE; GLUCOCORTICOID RECEPTOR; MIFEPRISTONE;

ARTICLE; ENZYME INDUCTION; GENETIC TRANSCRIPTION; HEPATOMA CELL; HUMAN; HUMAN CELL; POINT MUTATION; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; STEROID METABOLISM; TRANSCRIPTION INITIATION;

EID: 0031906058     PISSN: 10445498     EISSN: None     Source Type: Journal    
DOI: 10.1089/dna.1998.17.39     Document Type: Article

References (8)

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2. AOYAMA, T., YAMANO, S., WAXMAN, D.J., LAPENSON, D.P., MEYER, U.A., FISCHER, V., TYNDALE, R., INABA, T., KALOW, W., GELBOIN, H.V., and GONZALEZ, F.J. (1989). Cytochrome P-450 hPCN3, a novel cytochrome P-450 IIIA gene product that is differentially expressed in adult human liver. cDNA and deduced amino acid sequence and distinct specificities of cDNA-expressed hPCN1 and hPCN3 for the metabolism of steroid hormones and cyclosporine. J. Biol. Chem. 264, 10388-10395.
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5. BEN-OR, S., and OKRET, S. (1993). Involvement of a C/EBP-like protein in the acquisition of responsiveness to glucocorticoid hormones during chick neural retina development. Mol. Cell. Biol. 13,331-340.
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7. BRIAN, W.R., SARI, M.-A., IWASAKI, M., SHIMADA, T., KAMINSKY, L.S., and GUENGERICH, F.P. (1990). Catalytic activities of human liver cytochrome P-450 IIIA4 expressed in Sacharomyces cerevisiae. Biochemistry 29, 11280-11292.
8. BURGER, H.-J., SCHUETZ, J.D., SCHUETZ, E.G., and GUZELIAN, P.S. (1992). Paradoxical transcription activation of rat liver cytochrome P-450 3A1 by dexamethasone and antiglucocorticoid pregnenolone 16α-carbonitrile: analysis by transit transfection into primary monolayer cultures of adult rat hepatocytes. Proc. Natl. Acad. Sci. USA 89, 2145-2149.