Effects of tanshinone II-A sulfonate on adhesion molecule expression of endothelial cells and platelets in vitro

Acta Pharmacologica Sinica

Volumn 19, Issue 1, 1998, Pages 47-50

  Jiang, Kai Yu ^a   Ruan, Chang Geng ^a   Gu, Zhen Lun ^a   Wen Xuan, Zhou ^b   Ci Yi, Guo ^b  

^a Sudiou Medical College   (China)

^b Hong Kong Association for Health Care Ltd   (Hong Kong)

Author keywords

Blood platelets; Cell adhesion; Cell adhesion molecules; Flow cytometry; HL 60 cells; P selectin; Tanshinone II A; Thrombin; Tumor necrosis factor; Umbilical veins; Vascular endothelium

Indexed keywords

CELL ADHESION MOLECULE; INTERCELLULAR ADHESION MOLECULE 1; PADGEM PROTEIN; TANSHINONE; TANSHINONE IIA SULFONIC ACID; THROMBIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; CELL ADHESION; CELL STRAIN HL 60; CELL SURFACE; CONCENTRATION RESPONSE; DRUG INHIBITION; ENDOTHELIUM CELL; FLOW CYTOMETRY; GENE EXPRESSION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; THROMBOCYTE; UMBILICAL VEIN; VASCULAR ENDOTHELIUM;

BLOOD PLATELETS; CARDIOVASCULAR AGENTS; CELL ADHESION; CELL MEMBRANE; CELLS, CULTURED; DRUGS, CHINESE HERBAL; ENDOTHELIUM, VASCULAR; HL-60 CELLS; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; P-SELECTIN; PHENANTHRENES; UMBILICAL VEINS;

EID: 0031905929     PISSN: 02539756     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Li CZ, Yang SC, Zhao FD. Effect of tanshinone II -A sulfonate on thrombus formation, platelet and coagulation in rats and mice. Acta Pharmacol Sin 1984; 5: 39-42.
2. 2+-ATPase activity in platelets. Acta Acad Med Shanghai 1988; 15: 289-92.
3. Li, XH, Tang RY. Relationship between inhibitory action of tanshinone on neutrophil function and its prophylactic effects on myocardial infarction. Acta Pharmacol Sin 1991; 12: 269-72.
4. Xu LL, Wu Q, Wang BY, Yang XJ, Wu LP. Inhibitory effect of tanshinone on oxygen free radical production by human neutrophils. Chin J Pathophysiol 1994; 10: 635-8.
5. Wang SF, Gao JY, Zhang KJ, Wang CW. Effect of tanshinone on human polymorphonuclear leukocyte chemokinesis. Chin J Pathophysiol 1986; 2: 91-3.
6. Gao JY, Wang SF, Zhang KJ, Wang CW. Observation on inhibitory actions of tanshinone on leukocyte chemotaxis. Chin J Integ Trad West Med 1985; 5: 684-5.
7. Wu GX, Xi XD, U PX, Chu XH, Ruan CG. Preparation of a monoclonal antibody, SZ-51, that recognizes an α-granule membrane protein (GMP-140) on the surface of activated human platelets. Nouv Rev Fr Hematol 1990; 32: 231-5.
8. Wu GX, Xi XD, U PX, Ruan CG. SZ-51, a monoclonal antibody directed against human activated platelets. Chin J Hematol 1991; 12: 67-9.
9. Jaffe EA, Nachman RL, Becker CG, Minick CR. Culture of human endothelial cells derived from umbilical veins: identification by morphologic and immunologic criteria. J Clin Invest 1973; 52: 2745-56.
10. Chiang MY, Chan H, Zounes MA, Freier SM, Lima WF, Bennett CF. Antisense oligonucleotides inhibit intercellular adhesion molecule 1 expression by two distinct mechanisms. J Biol Chem 1991; 266: 18162-71.
11. Larsent E, Celi A, Gilbert GE, Furie BC, Erban JK, Bonfanti R, et al. PADGEM protein: a receptor that mediates the interaction of activated platelets with neutrophils and monocytes. Cell 1969; 59: 305-12.
12. Hamburger SA, McEver RP. GMP-140 mediates adhesion of stimulated platelets to neutrophils. Blood 1990; 75: 550-4.