A new concept of drug delivery for acne

Dermatology

Volumn 196, Issue 1, 1998, Pages 165-170

  Shroot, Braham ^a   Michel, S ^a   Allec, J ^a   Chatelus, A ^a   Wagner, N ^a  

^a Galderma R and D   (France)

Author keywords

Acne; Adapalene; Drug delivery; Follicular penetration; Retinoids

Indexed keywords

ADAPALENE; ANTI ACNE AGENT; RETINOIC ACID RECEPTOR;

ACNE; ANTIINFLAMMATORY ACTIVITY; CELL DIFFERENTIATION; CELL PROLIFERATION; CONFERENCE PAPER; DRUG DELIVERY SYSTEM; GENETIC TRANSCRIPTION; HUMAN; PRIORITY JOURNAL; TOPICAL DRUG ADMINISTRATION;

ACNE VULGARIS; ADMINISTRATION, TOPICAL; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELL DIFFERENTIATION; GELS; HUMANS; NAPHTHALENES; SKIN;

EID: 0031905664     PISSN: 10188665     EISSN: None     Source Type: Journal    
DOI: 10.1159/000017854     Document Type: Conference Paper

References (16)

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2. Shroot B: Medicinal chemistry in dermatology; in Priestley GC (ed): Molecular Aspects of Dermatology. Chichester, Wiley & Sons, 1993, pp 189-209.
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5. Bailly J, Delescluse C, Bernardon JM, Charpentier B, Martin B, Pilgrim WR, Shroot B, Darmon M: Differentiation of F9 embryonal carcinoma cells by synthetic retinoids: Amplitude of plasminogen activator production does not depend on retinoid potency or affinity for F9 nuclear retinoic acid receptors. Skin Pharmacol 1990;3:256-267.
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7. Lotan R, Kramer RH, Neumann G. Lotan D, Nicholson GL: Retinoic acid induced modifications in the growth and cell surface components of a human carcinoma (HeLa) cell line. Exp Cell Res 1980;130:401-414.
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10. Allec J, Chatelus A, Wagner N: Skin distribution and pharmaceutical aspects of adapalene gel. J Am Acad Dermatol, in press.
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12. Bouclier M, Luginbuhl B, Shroot B, Hensby CM: Arachidonic-acid-induced ear oedema in four strains of rats and mice: A comparative study of anti-inflammatory drugs. Agents Actions 1990;29:62-64.
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14. Chambon P: The retinoid signal pathway: Molecular and genetic analyses. Cell Biol 1994;5: 115-125.
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16. Elder JT, Aström A, Pettersson U, Tavakkol A, Griffiths CEM, Krust A, Kastner P, Chambon P, Voorhees JJ: Differential regulation of retinoic acid receptors and binding proteins in human skin. J Invest Dermatol 1992;98: 673-679.