Human herpesvirus 8 (HHV-8) in the pathogenesis of Kaposi's sarcoma and other diseases

Leukemia and Lymphoma

Volumn 28, Issue 3-4, 1998, Pages 255-264

  Humphrey, Rachel W ^a   Davis, David A ^a   Newcomb, Fonda M ^a   Yarchoan, Robert ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Castleman's disease; Herpesvirus; Kaposi's sarcoma; KSHV; Lymphoma

Indexed keywords

ANGIOFOLLICULAR LYMPH NODE HYPERPLASIA; ENDEMIC DISEASE; HOMOSEXUALITY; HUMAN; HUMAN HERPESVIRUS 8; IMMUNOSUPPRESSIVE TREATMENT; KAPOSI SARCOMA; LYMPHOMA; NONHUMAN; PRIORITY JOURNAL; REVIEW;

EID: 0031905552     PISSN: 10428194     EISSN: None     Source Type: Journal    
DOI: 10.3109/10428199809092681     Document Type: Review

References (73)

1. Armes, J. (1989). A review of Kaposi's sarcoma. Adv Cancer Res, 53, 73-87.
2. DiGiovanna, J. J. and Safai, B. (1981). Kaposi's sarcoma. Retrospective study of 90 cases with particular emphasis on the familial occurrence, ethnic background and prevalence of other diseases. Am J Med, 71(5), 779-83.
3. McHardy, J., Williams, E. H., Gese, A., de-The, G., Beth, E. and Giraldo, G. (1984). Endemic Kaposi's sarcoma: incidence and risk factors in the West Nile District of Uganda. Int J Cancer, 33(2), 203-12.
4. Bayley, A. C. (1991). Occurrence, clinical behaviour and management of Kaposi's sarcoma in Zambia. Cancer Surv, 10, 53-71.
5. Penn, I. (1993). Tumors after renal and cardiac transplantation. Hematol Oncol Clin North Am, 7(2), 431-45.
6. Brunner, F. P., Landais, P. and Selwood, N. H. (1995). Malignancies after renal transplantation: the EDTA-ERA registry experience. European Dialysis and Transplantation Association-European Renal Association. Nephrol Dial Transplant, 10(1), 74-80.
7. Montagnino, G., Bencini, P. L., Tarantino, A., Caputo, R. and Ponticelli, C. (1994). Clinical features and course of Kaposi's sarcoma in kidney transplant patients: report of 13 cases. Am J Nephrol, 14(2), 121-6.
8. Beral, V., Peterman, T. A., Berkelman, R. L. and Jaffe, H. W. (1990). Kaposi's sarcoma among persons with AIDS: a sexually transmitted infection? [see comments]. Lancet, 335(8682), 123-8.
9. Friedman-Kien, A. E., Saltzman, B. R., Cao, Y. Z., et al. (1990). Kaposi's sarcoma in HIV-negative homosexual men [letter]. Lancet, 335(8682), 168-9.
10. Afrasiab, R., Mitsuyasu, R. T., Nishanian, P., Schwartz, K. and Fahey, J. L. (1986). Characterization of a distinct subgroup of high-risk persons with Kaposi's sarcoma and good prognosis who present with normal T4 cell number and T4:T8 ratio and negative HTLV-III/LAV serologic test results. Am J Med, 81(6), 969-73.
11. Giraldo, G., Beth, E. and Huang, E. S. (1980). Kaposi's sarcoma and its relationship to cytomegalovirus (CMNV). III. CMV DNA and CMV early antigens in Kaposi's sarcoma. Int J Cancer, 26(1), 23-9.
12. Giraldo, G., Beth, E., Kourilsky, F. M., et al. (1975). Antibody patterns to herpesviruses in kaposi's sarcoma: serological association of european kaposi's sarcoma with cytomegalovirus. Int J Cancer, 15(5), 839-48.
13. Siddiqui, A. (1983). Hepatitis B virus DNA in Kaposi sarcoma. Proc Natl Acad Sci USA, 80(15), 4861-4.
14. Marmor, M., Friedman-Kien, A. E., Laubenstein, L., et al. (1982). Risk factors for Kaposi's sarcoma in homosexual men. Lancet, 1(8281), 1083-7.
15. Morabia, A. (1995). Poppers, Kaposi's sarcoma, and HIV infection: empirical example of a strong confounding effect. Prev Med, 24, 90-95.
16. Fiorelli, V., Gendelman, R., Samaniego, F., Markham, P. D. and Ensoli, B. (1995). Cytokines from activated T cells induce normal endothelial cells to acquire the phenotypic and functional features of AIDS-Kaposi' s sarcoma spindle cells. J Clin Invest, 95(4), 1723-34.
17. Chang, Y., Cesarman, E., Pessin, M. et al. (1994). Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma. Science, 266, 1865-1869.
18. Moore, P., Gao, S-J., Dominguez, G., et al. (1996). Primary characerization of a herpesvirus agent associated with Kaposi's Sarcoma. J. Virol, 70(1), 549-558.
19. Chang, Y. and Moore, P. S. (1996). Kaposi's Sarcoma (KS)-associated herpesvirus and its role in KS. Infect Agents Dis, 5(4), 215-22.
20. Nador, R. G., Cesarman, E., Chadburn, A., et al. (1996). Primary effusion lymphoma: a distinct clinicopathologic entity associated with the Kaposi's sarcoma-associated herpes virus. Blood, 88(2), 645-56.
21. Dupin, N., Gorin, I., Deleuze, J., et al. (1995). Herpes-like DNA sequences, AIDS-related tumors, and Castleman's disease [letter]. N Engl J Med, 333(12), 798; discussion 798-9.
22. Karcher, D. S. and Alkan, S. (1995). Herpes-like DNA sequences, AIDS-related tumors, and Castleman's disease [letter; comment]. N Engl J Med, 333(12), 797-8; discussion 798-9.
23. Giraldo, G., Beth, E., Coeur, P., Vogel, C. L. and Dhru, D. S. (1972). Kaposi's sarcoma: a new model in the search for viruses associated with human malignancies. J Natl Cancer Inst, 49(6), 1495-507.
24. Giraldo, G., Beth, E. and Kyalwazi, S. K. (1984). Role of cytomegalovirus in Kaposi's sarcoma. IARC Sci Publ, (63), 583-606.
25. Rady, P., Yen, A., Rollefson, J., et al. (1995). Herpesvirus-like DNA sequences in non-Kaposi's sarcoma skin lesions of transplant patients. The Lancet, 345, 1339-1340.
26. Dupin, N., Grandadam, M., Calvez, V., et al. (1995). Herpesvirus-like DNA sequences in patients with Mediterranean Kaposi's sarcoma. The Lancet, 345, 761-762.
27. Bochoff, C., Whitby, D., Hatziioannou, T., et al. (1995). Kaposi's-sarcoma-associated herpesvirus in HIV-negative Kaposi's sarcoma. Lancet, 345, 1043-44.
28. Huang, Y., Li, J., Kaplan, M., et al. (1995). Human herpesvirus-like nucleic acid in various forms of Kaposi's sarcoma. The Lancet, 345, 759-761.
29. Schalling, M., Ekman, M., Kaaya, E. E., Linde, A. and Biberfeld, P. (1995). A role for a new herpes virus (KSHV) in different forms of Kaposi's sarcoma. Nat Med, 1(7), 707-8.
30. Whitby, D., Howard, M., Tenant-Flowers, M., et al. (1995). Detection of Kaposi sarcoma associated herpesvirus in peripheral blood of HIV-infected individuals and progression to Kaposi's sarcoma. Lancet, 346, 799-802.
31. Moore, P., Kingsley, L., Holmberg, S., et al. (1995). Kaposi's sarcoma-associated herpesvirus infection prior to the onset of Kaposi's sarcoma. AIDS, 10, 175-180.
32. Lin, J. C., Lin, S. C., Mar, E. C., et al. (1995). Is Kaposi's-sarcoma-associated herpesvirus detectable in semen of HIV-infected homosexual men? Lancet., 346(8990), 1601-2.
33. Gao, S-J., Kingsley, L., Hoover, D., et al. (1996). Seroconversion to antibodies against kaposi's sarcoma-associated herpesvirus-related latent nuclear antigens before the development of kaposi's sarcoma. N Engl J Med, 335, 233-41.
34. Lennette, E., Blackbourn, D. and Levy, J. (1996). Antibodies to human herpesvirus type 8 in the general population and in kaposi's sarcoma patients. Lancet, 348, 858-61.
35. Davis, D., Humphrey, R., Newcomb, F., et al. (1997). Detection of serum antibodies to a kaposi's sarcoma associated herpesvirus-specific peptide. Jour. Infect. Dis., in press.
36. Said, W., Chien, K., Takeuchi, S., et al. (1996). Kaposi's sarcoma-associated herpesvirus (KSHV or HHV8) in primary effusion lymphoma: ultrastructural demonstration of herpesvirus in lymphoma cells. Blood, 87(12), 4937-43.
37. Corbellino, M., Poirel, L., Bestetti, G., et al. (1996). Human herpesvirus-8 in AIDS-related and unrelated lymphomas [letter]. Aids, 10(5), 545-6.
38. Luppi, M., Barozzi, P., Maiorana, A., et al. (1996). Human herpesvirus-8 DNA sequences in human immunodeficiency virus-negative angioimmunoblastic lymphadenopathy and benign lymphadenopathy with giant germinal center hyperplasia and increased vascularity. Blood, 87(9), 3903-9.
39. Humphrey, R., O'Brien, T., Newcomb, F., et al. (1996). Kaposi's sarcoma (KS)-associated herpesvirus-like DNA sequences in peripheral blood mononuclear cells: association with KS and persistence in patients receiving anti-herpesvirus drugs. Blood, 88, 297-301.
40. Bigoni, B., Dolcetti, R., Lelli, L. D., et al. (1996). Human Herpesvirus 8 is Present in the Lymphoid System of Healthy Persons and Can Reactivate in the Course of AIDS. J. Infect. Dis., 173, 542-549.
41. Corbellino, M., Bestetti. G., Poirel, L., et al. (1996). Is human herpesvirus type 8 fairly prevalent among healthy subjects in Italy? [letter]. J Infect Dis, 174(3), 668-70.
42. Monini, P., DeLellis, L., Fabris, M., Rigolin, F. and Cassai, E. (1996). Kaposi's sarcoma-associated herpesvirus DNA sequences in prostate tissue and human semen. NEJM, 334, 1168-72.
43. Ambroziak, J. A., Blackbourn, D. J., Herndier, B. G., et al. (1995). Herpes-like sequences in HIV-infected and uninfected Kaposi's sarcoma patients [letter; comment]. Science, 268(5210), 582-3.
44. Humphrey, R., Davis, D., Newcomb, F., et al. (1996). Analysis of human herpesvirus-8 infection in children and adults by measuring serum antibodies to a peptide of a minor capsid protein or by PCR. J. AIDS Hum. Retro., IHV Abstracts, 56.
45. Simpson, G., Schulz, T., Whitby, D., et al. (1996). Prevalence of kaposi's sarcoma associated herpesvirus infection measured by antibodies to recombinant capsid protein and latent immunofluorescence antigen. Lancet, 349, 1133-38.
46. Kedes, D., Operskalski, E., Busch, M., Kohn, R., Flood, J. and Ganem, D. (1996). The seroepidemiology of human herpesvirus 8 (Kaposi's sarcoma-associated herpesvirus): Distribution of infection in KS risk groups and evidence for sexual transmission. Nature Medicine, 2, 918-924.
47. Gao, S-J., Kingsley, L., Li, M. et al. (1996). KSHV antibodies among Americans, Italians and Ugandans with and without Kaposi's sarcoma. Nat. Med., 2, 925-928.
48. Jameson, B. and Wolf, H. (1988). A novel algorithm, for predicting antigenic determinants. Comput Applic Biosci, 4, 181-6.
49. Weller, T. (1971). The cytomegalovirus: ubiquitous agents with protean clinical manifestations. N Engl J Med, 285, 203-214.
50. Morris, J., Eddleston, A. and Crook, T. (1995). Viral infection and cancer. Lancet, 346, 754-758.
51. Cleary, M. L., Smith, S. D. and Sklar, J. (1986). Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation. Cell, 47(1), 19-28.
52. Moore, P., Boshoff, C., Weiss, R. and Chang, Y. (1996). Molecular mimicry of human cytokine and cytokine response pathway genes by KSHV. Science, 274, 1739-1744.
53. Chang, Y., Moore, P., Talbot, S., et al. (1996). Cyclin encoded by KS herpesvirus. Nature, 382, 410.
54. Russo, J. J., Bohenzky, R. A., Chien, M. C., et al. (1996). Nucleotide sequence of the Kaposi sarcoma-associated herpesvirus (HHV8). Proc Natl Acad Sci USA, 93(25), 14862-7.
55. Soulier, J.,Grollet, L., Oksenhendler, E., et al. (1995). Kaposi's sarcoma-associated herpesvirus-like DNA sequences in multicentric Castleman's disease. Blood, 86(4), 1276-80.
56. Yoshizaki, K., Matsuda, T., Nishimoto, N., et al. (1989). Pathogenic significance of interleukin-6 (IL-6/BSF-2) in Castleman's disease. Blood, 74(4), 1360-7.
57. Ishiyama, T., Nakamura, S., Akimoto, Y., et al. (1994). Immunodeficiency and IL-6 production by peripheral blood monocytes in multicentric Castleman's disease. Br. J Haematol, 86(3), 483-9.
58. Giraudo, E., Arese, M., Toniatti, C., et al. (1996). IL-6 is an in vitro and in vivo autocrine growth factor for middle T antigen-transformed endothelial cells. J Immunol, 157(6), 2618-23.
59. Murakami-Mori, K., Taga, T., Kishimoto, T. and Nakamura, S. (1996). The soluble form of the IL-6 receptor (sIL-6R alpha) is a potent growth factor for AIDS-associated Kaposi's sarcoma (KS) cells; the soluble form of gp 130 is antagonistic for sIL-6R alpha-induced AIDS-KS cell growth. Int Immunol, 8(4), 595-602.
60. Jones, K., Rivera, C., Sgadari, C., et al. (1995). Infection of human endothelial cells with Epstein-Barr virus. J Exp Med, 182(5), 1213-21.
61. Tosato, G., Tanner, J., Jones, K. D., Revel, M. and Pike, S. E. (1990). Identification of interleukin-6 as an autocrine growth factor for Epstein-Barr virus-immortalized B cells. J Virol, 64(6), 3033-41.
62. Tosato, G and Jones, K. D. (1990). Interleukin-1 induces interleukin-6 production in peripheral blood monocytes. Blood, 75(6), 1305-10.
63. Oksenhendler, E., Duarte, M., Soulier, J., et al. (1996). Multicentric Castleman's disease in HIV infection: a clinical and pathological study of 20 patients. Aids, 10(1), 61-7.
64. Zhong, W., Wang, H., Herndier, B. and Ganem, D. (1996). Restricted expression of Kaposi sarcoma-associated herpesvirus (human herpesvirus 8) genes in Kaposi sarcoma. Proc Natl Acad Sci U S A, 93(13), 6641-6.
65. Jones, J., Hanson, D., Chu, S., Ward, J. and Jaffe, H. (1995). AIDS-associated Kaposi's sarcoma. Science, 267, 1078-1080.
66. Costagliola, D. and Mary-Krause, M. (1995). Can antiviral agents decrease the occurrence of Kaposi's sarcoma? Clinical Epidemiology Group from Centres d'Information et de Soins de l'Immunodeficience Humaine [letter]. Lancet, 346(8974), 578.
67. Morfeldt, L. and Torssander, J. (1994). Long-term remission of Kaposi's sarcoma following foscarnet treatment of HIV-infected patients. Scad J Infect Dis, 26, 749-752.
68. Tosato, G. (1987). The Epstein-Barr virus and the immune system. Adv Can Res, 49, 75-125.
69. Resnick, L., Herbst, J. and Ablashi, D. (1988). Regression of oral "hairy" leukoplakia after orally administered acyclovir therapy. JAMA, 15, 384-388.
70. Nicholson, A. G., Wotherspoon, A. C., Diss, T. C., et al. (1996). Lymphomatoid granulomatosis: evidence that some cases represent Epstein-Barr virus-associated B-cell lymphoma. Histopathology, 29(4), 317-24.
71. Hui, P. K., Tokunaga, M., Chan, W. Y., Ng, C. S., Chow, J. and Lee, J. C. (1994). Epstein-Barr virus-associated gastric lymphoma in Hong Kong Chinese. Hum Pathol, 25(9), 947-52.
72. Mueller, N. (1995). Overview: viral agents and cancer. Environ Health Perspect, 103 Suppl 8, 259-61.
73. Ambinder, R. F. (1990). Human lymphotropic viruses associated with lymphoid malignancy: Epstein-Barr and HTLV-1. Hematol Oncol Clin North Am, 4(4), 821-33.